Digestive Endoscopy最新文献

{"title":"Wave height fluctuations in the waveforms of an endoscopic pressure study integrated system have the potential to predict acid reflux in gastroesophageal reflux disease (with video)","authors":"Satoshi Abiko,&nbsp;Yuto Shimamura,&nbsp;Haruhiro Inoue,&nbsp;Masachika Saino,&nbsp;Kei Ushikubo,&nbsp;Miyuki Iwasaki,&nbsp;Kazuki Yamamoto,&nbsp;Yohei Nishikawa,&nbsp;Ippei Tanaka,&nbsp;Hidenori Tanaka,&nbsp;Mayo Tanabe,&nbsp;Boldbaatar Gantuya,&nbsp;Manabu Onimaru,&nbsp;Naoya Sakamoto","doi":"10.1111/den.15049","DOIUrl":"10.1111/den.15049","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>The endoscopic pressure study integrated system (EPSIS) is a useful diagnostic tool for gastroesophageal reflux disease (GERD). Although wave height fluctuations have been observed in EPSIS waveforms, their clinical significance remains unclear. We hypothesized that the magnitude of these fluctuations may reflect lower esophageal sphincter functionality. This study aimed to evaluate the association between wave height fluctuations and objective acid reflux parameters.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A retrospective analysis was conducted on patients with GERD symptoms who underwent both EPSIS and 24-h multichannel intraluminal impedance-pH monitoring at a single tertiary center between June 2020 and December 2023. Abnormal acid reflux was defined as an acid exposure time (AET) ≥6.0%. Wave height was defined as the difference in intragastric pressure between the crest and trough of the EPSIS waveform. A diagnostic cut-off value for wave height was determined, and factors associated with elevated wave height were analyzed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 129 patients were included, of whom 29 (22.5%) had abnormal acid reflux. The median wave height was 2.5 mmHg. Patients with AET ≥6% had significantly higher wave heights than those with AET &lt;6% (<i>P</i> = 0.0141). A wave height of 3.1 mmHg demonstrated optimal diagnostic performance for predicting abnormal AET. Multivariate analysis revealed that abnormal AET (odds ratio 3.43, 95% confidence interval 1.39–8.44, <i>P</i> = 0.0074) was independently associated with wave heights ≥3.1 mmHg.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Wave height fluctuations in EPSIS waveforms may reflect lower esophageal sphincter dysfunction and serve as a novel predictor of pathological acid reflux in patients with GERD.</p>\u0000 </section>\u0000 </div>","PeriodicalId":159,"journal":{"name":"Digestive Endoscopy","volume":"37 9","pages":"981-988"},"PeriodicalIF":4.7,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144188620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Kaizen: Perpetual improvement in biliary ablation – From technical validation to clinical translation","authors":"Eisuke Iwasaki,&nbsp;Fateh Bazerbachi","doi":"10.1111/den.15053","DOIUrl":"10.1111/den.15053","url":null,"abstract":"&lt;p&gt;The evolution of minimally invasive endoscopic techniques has established endoscopic papillectomy (EP) as a primary treatment for ampullary adenomas, with support from international guidelines.&lt;span&gt;&lt;sup&gt;1, 2&lt;/sup&gt;&lt;/span&gt; Despite its widespread adoption and proven efficacy, EP faces a critical challenge: the management of residual lesions that extend into the biliary or pancreatic ducts. These intraductal extensions present a unique therapeutic dilemma, as conventional ablative techniques like argon plasma coagulation and additional endoscopic resection often prove inadequate.&lt;span&gt;&lt;sup&gt;3&lt;/sup&gt;&lt;/span&gt; While intraductal radiofrequency ablation (ID-RFA) has emerged as a promising solution, having demonstrated success in biliary malignancy, its application in post-EP scenarios requires technical validation. The optimization of device settings, particularly with newer-generation radiofrequency (RF) generator, represents a knowledge gap that impacts both treatment efficacy and safety.&lt;/p&gt;&lt;p&gt;RFA has evolved from its established applications in Barrett's esophagus and hepatocellular carcinoma to become an increasingly refined tool for biliary interventions. The technology's core strength lies in its precise delivery of thermal energy through bipolar electrode arrays, achieving controlled coagulative necrosis in confined anatomical spaces. Modern RFA systems pair sophisticated generators with specialized catheters, enabling precise control of both voltage and power – critical parameters that determine treatment efficacy and safety in the biliary tract.&lt;/p&gt;&lt;p&gt;The study by Yamamoto &lt;i&gt;et al&lt;/i&gt;., published in this issue of &lt;i&gt;Digestive Endoscopy&lt;/i&gt;, provides crucial insights into the technical optimization of ID-RFA through a comprehensive three-tier investigation.&lt;span&gt;&lt;sup&gt;4&lt;/sup&gt;&lt;/span&gt; Their methodical approach commenced with in-vitro validation using porcine liver models, which revealed a critical technical principle: achieving the desired ablation effect requires sufficient voltage to enable the generator to reach its set power output. This initial phase allowed precise measurement of ablation patterns and tissue effects under controlled conditions. Building on these findings, they progressed to in-vivo experiments in live porcine models, where they could evaluate the real-time tissue response and assess healing patterns over time. Through systematic comparison with the conventional VIO300D generator (Erbe, Tübingen, Germany), they established optimal parameters for the newer VIO3 system (bipolar 3.0, 125 Vp, 30 W, 30 s) (Erbe, Tübingen, Germany) to achieve effective ablation patterns. Their findings translated successfully to clinical practice, with their preliminary five-patient experience demonstrating complete ablation without recurrence over a median 24-month follow-up period. A key advantage of the VIO3 system is its ability to display real-time power output during the procedure, providing better visualization of the automatic power reducti","PeriodicalId":159,"journal":{"name":"Digestive Endoscopy","volume":"37 9","pages":"955-957"},"PeriodicalIF":4.7,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/den.15053","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144153055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endoscopic ultrasound-guided tissue acquisition for assessment of resectability in pancreatobiliary cancer","authors":"Yasunobu Yamashita,&nbsp;Masayuki Kitano","doi":"10.1111/den.15052","DOIUrl":"10.1111/den.15052","url":null,"abstract":"&lt;p&gt;Five-year survival rates for pancreatic cancer and biliary tract cancer are the first and second poorest, respectively, among all cancers in Japan. In clinical practice, computed tomography (CT) and other imaging modalities play a major role in determining treatment options, including surgery. Patients with pancreatic cancer are divided into three groups (i.e., resectable, borderline resectable, and unresectable). The degree of tumor invasion into the great vessels determines resectability. Therefore, diagnosis of perivascular soft-tissue cuffing (PSTC) is important when deciding whether a tumor is resectable.&lt;span&gt;&lt;sup&gt;1&lt;/sup&gt;&lt;/span&gt;&lt;/p&gt;&lt;p&gt;Some pancreatobiliary cancers appear as PSTC on CT and magnetic resonance imaging (MRI). PSTC is thought to be caused by the complexity of lymphatic drainage,&lt;span&gt;&lt;sup&gt;2&lt;/sup&gt;&lt;/span&gt; a process called extravascular migratory metastasis (EVMM); however, differential diagnoses of PSTC include benign diseases such as retroperitoneal fibrosis and chronic pancreatitis. Diagnosis of EVMM among PSTCs on CT and MRI is difficult due to nonspecific, often diminutive, overlapping imaging features indicative of inflammation, as well as changes induced by therapy.&lt;/p&gt;&lt;p&gt;Endoscopic ultrasound (EUS) is superior to other modalities for detection of small lesions due to its superior spatial resolution.&lt;span&gt;&lt;sup&gt;3&lt;/sup&gt;&lt;/span&gt; Moreover, preoperative EUS is better than CT for diagnosing vascular invasion by pancreatic cancer. In fact, a meta-analysis of nine studies comparing EUS with CT for assessment of vascular invasion by pancreatic cancer revealed that the diagnostic abilities of EUS and CT were a sensitivity of 69% and 48%, respectively, with an area under the curve (AUC) of 0.94 and 0.86, respectively.&lt;span&gt;&lt;sup&gt;4&lt;/sup&gt;&lt;/span&gt; In addition, EUS-guided tissue acquisition (EUS-TA) enables a pathological diagnosis based on samples taken from lesions; this is especially important in cases where the differential diagnosis of PSTC is difficult, or when PSTC is detected by EUS alone. Moreover, accurate diagnosis based on EUS-TA is important for determining treatment strategies and avoiding unnecessary surgery. However, it should be noted that the accuracy of EUS-TA depends on the skill level of the endoscopist (i.e., expert vs. nonexpert).&lt;/p&gt;&lt;p&gt;Maehara &lt;i&gt;et al&lt;/i&gt;. reported the sensitivity, specificity, and accuracy of EUS-TA for PSTC as 92.1%, 100%, and 92.5%, respectively, with a technical success rate of 98.1%.&lt;span&gt;&lt;sup&gt;5&lt;/sup&gt;&lt;/span&gt; There are only two previous reports of EUS-TA for PSTC.&lt;span&gt;&lt;sup&gt;6, 7&lt;/sup&gt;&lt;/span&gt; One of these found that the diagnostic yield of PSTC by EUS-guided fine-needle aspiration was 65%.&lt;span&gt;&lt;sup&gt;7&lt;/sup&gt;&lt;/span&gt; Another recent report found that EUS-TA for PSTC had a sensitivity, specificity, and diagnostic accuracy of 81.1%, 100%, and 85.8%, respectively.&lt;span&gt;&lt;sup&gt;6&lt;/sup&gt;&lt;/span&gt; Compared with previous reports,&lt;span&gt;&lt;sup&gt;6, 7&lt;/sup&gt;&lt;/span&gt; the data presented in that report&lt;span&gt;&lt;sup&gt;5&lt;/sup&gt;&lt;/sp","PeriodicalId":159,"journal":{"name":"Digestive Endoscopy","volume":"37 9","pages":"958-959"},"PeriodicalIF":4.7,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/den.15052","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144103250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility of endoscopic transpapillary gallbladder drainage for acute gangrenous cholecystitis in poor surgical candidates","authors":"Kazunari Nakahara,&nbsp;Shinjiro Kobayashi,&nbsp;Tsuyoshi Morimoto,&nbsp;Yosuke Igarashi,&nbsp;Akihiro Sekine,&nbsp;Yusuke Satta,&nbsp;Haruka Niwa,&nbsp;Junya Sato,&nbsp;Tomoko Norose,&nbsp;Nobuyuki Ohike,&nbsp;Keisuke Tateishi","doi":"10.1111/den.15050","DOIUrl":"10.1111/den.15050","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Surgery is generally the first choice of treatment for gangrenous cholecystitis (GC). However, some patients are not fit for surgery because of their comorbidities. We evaluated the feasibility of endoscopic transpapillary gallbladder drainage (ETGBD) for GC in poor surgical candidates.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This retrospective study compared the outcomes of ETGBD for acute cholecystitis (AC) with and without complicated GC. Of the 136 patients who underwent ETGBD for AC at a single tertiary referral center between January 2019 and July 2023, 91 who underwent contrast-enhanced computed tomography (CT) before ETGBD were included in the analysis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Patients were assigned to the GC (<i>n</i> = 29) and non-GC (<i>n</i> = 62) groups based on CT findings. The technical success rate of ETGBD, clinical success rate for AC, and rate of early adverse events (AEs) in the GC and non-GC groups were 86.2% vs. 91.9% (<i>P</i> = 0.63), 79.3% vs. 91.9% (<i>P</i> = 0.17), and 27.6% vs. 16.1% (<i>P</i> = 0.32), respectively. The technical and clinical success rates were slightly lower, while the early AE rate was higher in the GC group. However, the differences were not significant. The incidence of late AEs was 15.8% in the GC group and 17.9% in the non-GC group, with no significant difference (<i>P</i> = 0.87). Elective cholecystectomy was significantly less frequent in the GC group (<i>P</i> = 0.023).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>ETGBD is a feasible treatment option for GC in patients contraindicated for surgery.</p>\u0000 </section>\u0000 </div>","PeriodicalId":159,"journal":{"name":"Digestive Endoscopy","volume":"37 9","pages":"989-997"},"PeriodicalIF":4.7,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144112393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Truth will out: Endoscopic ultrasound-guided fine-needle biopsy for appendiceal adenocarcinoma","authors":"Xin Li,&nbsp;Xu-dong Wen,&nbsp;Wei-hui Liu","doi":"10.1111/den.15048","DOIUrl":"10.1111/den.15048","url":null,"abstract":"<p>Watch a video of this article.</p>","PeriodicalId":159,"journal":{"name":"Digestive Endoscopy","volume":"37 9","pages":"1014-1015"},"PeriodicalIF":4.7,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144095844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Computer-aided diagnosis for colorectal polyp in comparison with endoscopists: Systematic review and meta-analysis","authors":"Satoshi Shinozaki,&nbsp;Jun Watanabe,&nbsp;Takeshi Kanno,&nbsp;Yuhong Yuan,&nbsp;Tomonori Yano,&nbsp;Hironori Yamamoto","doi":"10.1111/den.15047","DOIUrl":"10.1111/den.15047","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Computer-aided diagnosis (CADx) is anticipated to enhance the prediction of colorectal polyp histology. This study aims to compare the diagnostic accuracy of CADx in the optical diagnosis of colorectal polyps, evaluating its performance against that of both experienced and inexperienced endoscopists.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The protocol of this study was registered in the International Prospective Register of Systematic Reviews (PROSPERO) (ID: CRD42024585097). Three electronic databases including MEDLINE, Embase, and the Cochrane Central Register of Controlled Trials (CENTRAL) were searched in September 2024. A bivariate random effects model was employed. The primary outcome was the comparison of sensitivity and specificity between CADx and experienced endoscopists; the secondary outcome was the comparison between CADx and inexperienced endoscopists.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Twenty-one studies involving 5477 polyps were included. The pooled sensitivities of CADx and experienced endoscopists were 0.87 (95% confidence interval [CI] 0.82–0.91) and 0.88 (95% CI 0.83–0.91), respectively (<i>P</i> = 0.93). The pooled specificities of CADx and experienced endoscopists were 0.85 (95% CI 0.78–0.90) and 0.87 (95% CI 0.82–0.92), respectively (<i>P</i> = 0.53). In nine studies comparing CADx with inexperienced endoscopists, the pooled sensitivities were 0.88 (95% CI 0.82–0.92) for CADx and 0.85 (95% CI 0.78–0.90) for inexperienced endoscopists (<i>P</i> = 0.46). The pooled specificities were 0.84 (95% CI 0.78–0.88) for CADx and 0.77 (95% CI 0.70–0.83) for inexperienced endoscopists (<i>P</i> = 0.16).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Computer-aided diagnosis does not demonstrate superior diagnostic accuracy in optical diagnosis of colorectal polyps compared to endoscopists, regardless of their experience level.</p>\u0000 </section>\u0000 </div>","PeriodicalId":159,"journal":{"name":"Digestive Endoscopy","volume":"37 9","pages":"933-947"},"PeriodicalIF":4.7,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/den.15047","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144082500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Painless pancreatic stones still need further discussion","authors":"Feng-Dong Wang","doi":"10.1111/den.15045","DOIUrl":"10.1111/den.15045","url":null,"abstract":"","PeriodicalId":159,"journal":{"name":"Digestive Endoscopy","volume":"37 9","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144082502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endoscopic features differentiating non-Helicobacter pylori Helicobacter-induced gastric mucosa-associated lymphoid tissue lymphoma with a nodular gastritis-like appearance and H. pylori-induced conventional nodular gastritis","authors":"Yuki Kitadai,&nbsp;Hidehiko Takigawa,&nbsp;Daisuke Shimizu,&nbsp;Misa Ariyoshi,&nbsp;Akiyoshi Tsuboi,&nbsp;Hidenori Tanaka,&nbsp;Ken Yamashita,&nbsp;Yuichi Hiyama,&nbsp;Yoshihiro Kishida,&nbsp;Yuji Urabe,&nbsp;Akira Ishikawa,&nbsp;Toshio Kuwai,&nbsp;Shiro Oka","doi":"10.1111/den.15042","DOIUrl":"10.1111/den.15042","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Conventional nodular gastritis has been known to be caused by <i>Helicobacter pylori</i> infection. Several cases of gastric mucosa-associated lymphoid tissue (MALT) lymphoma with non-<i>H. pylori Helicobacters</i> (NHPH) exhibit endoscopic findings resembling nodular gastritis. Considering the differences in malignancy, distinguishing between these two conditions is crucial. This study aimed to identify the distinguishing endoscopic features of NHPH-induced gastric MALT lymphoma with nodular gastritis-like appearance (NHPHi-MNG) and <i>H.</i>-induced conventional nodular gastritis (HPi-NG).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Between 2011 and 2022, we analyzed 17 patients with NHPHi-MNG and 50 patients with HPi-NG at Hiroshima University Hospital and evaluated nodule morphology and distribution patterns.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Compared with the HPi-NG group, the NHPHi-MNG group exhibited significantly larger nodules (2.5 vs. 2.0 mm, <i>P</i> &lt; 0.05) with protruded morphology (protruded/superficial, elevated: 14/3 vs. 8/42, <i>P</i> &lt; 0.05), most prominently in the gastric angulus. The variability in nodule size was significantly higher in the NHPHi-MNG group than in the HPi-NG group (0.85 vs. 0.37 mm, <i>P</i> &lt; 0.05), reflecting nodule heterogeneity. The distance from the gastric angulus to the proximal end of the nodular lesions was significantly greater in the NHPHi-MNG group than in the HPi-NG group (4.4 vs. 1.7 cm, <i>P</i> &lt; 0.05). The nodules in the HPi-NG group were smaller, superficial, elevated, and most prominent in the gastric antrum compared with those in the NHPHi-MNG group. They were predominantly distributed in the gastric antrum with a homogeneous morphology.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>NHPHi-MNG and HPi-NG can be endoscopically differentiated according to nodule morphology and distribution. Recognizing these distinguishing features is essential for an accurate diagnosis.</p>\u0000 </section>\u0000 </div>","PeriodicalId":159,"journal":{"name":"Digestive Endoscopy","volume":"37 9","pages":"998-1009"},"PeriodicalIF":4.7,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/den.15042","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144044001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Best Reviewers Award for 2024","authors":"","doi":"10.1111/den.15031","DOIUrl":"https://doi.org/10.1111/den.15031","url":null,"abstract":"<p>\u0000 <b>Best Reviewers for 2024</b>\u0000 </p><p>\u0000 <b>Yusuke Horiuchi</b>\u0000 </p><p>\u0000 <b>Ken Inoue</b>\u0000 </p><p>\u0000 <b>Fumiaki Ishibashi</b>\u0000 </p><p>\u0000 <b>Takuya Ishikawa</b>\u0000 </p><p>\u0000 <b>Yasuharu Maeda</b>\u0000 </p><p>\u0000 <b>Akinori Maruta</b>\u0000 </p><p>\u0000 <b>Yosuke Minoda</b>\u0000 </p><p>\u0000 <b>Jun Miyoshi</b>\u0000 </p><p>\u0000 <b>Yasuhisa Mori</b>\u0000 </p><p>\u0000 <b>Takeshi Okamoto</b>\u0000 </p><p>\u0000 <b>Taishi Okumura</b>\u0000 </p><p>\u0000 <b>Shunsuke Omoto</b>\u0000 </p><p>\u0000 <b>Tatsunori Satoh</b>\u0000 </p><p>\u0000 <b>Hisashi Shiga</b>\u0000 </p><p>\u0000 <b>Ayaka Takasu</b>\u0000 </p><p>\u0000 <b>Yuki Tanisaka</b>\u0000 </p><p>\u0000 <b>Yosuke Toya</b>\u0000 </p><p>\u0000 <b>Daisuke Yamaguchi</b>\u0000 </p><p>\u0000 <b>Kazuki Yamamoto</b>\u0000 </p><p>\u0000 <b>Shinji Yoshii</b>\u0000 </p><p>\u0000 <b>\u0000 <i>Distinguished Reviewers - Reviewers who have received DEN Best Reviewers Award 3 or more times -</i>\u0000 </b>\u0000 </p><p><i>Seiichiro Abe, Osamu Dohi, Mitsuru Esaki, Motohiro Esaki, Yoshihiro Furuichi, Waku Hatta, Takuto Hikichi, Kenichiro Imai, Hirotoshi Ishiwatari, Hiroshi Kawakami, Hideki Kobara, Hiroki Kurumi, Masaki Kuwatani, Kosuke Minaga, Masanao Nakamura, Hiroki Sato, Yuto Shimamura, Mitsushige Sugimoto, Kazunori Takada, Yoji Takeuchi, Toshio Uraoka, Yasushi Yamasaki</i>.</p>","PeriodicalId":159,"journal":{"name":"Digestive Endoscopy","volume":"37 5","pages":"563-565"},"PeriodicalIF":5.0,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/den.15031","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143926145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"WEO Newsletter: The Impact of Artificial Intelligence on Gastrointestinal Endoscopy","authors":"","doi":"10.1111/den.15036","DOIUrl":"https://doi.org/10.1111/den.15036","url":null,"abstract":"<p>WEO Newsletter Editor: Nalini M Guda MD, MASGE, AGAF, FACG, FJGES</p><p>Michael B. Wallace MD MPH</p><p>John C. Anderson Professor of Medicine, Mayo Clinic Florida</p><p>Artificial intelligence (AI) is rapidly transforming the field of gastrointestinal (GI) endoscopy, enhancing diagnostic accuracy, efficiency, and workflow optimization. AI-driven technologies, including deep learning algorithms and computer-aided detection and diagnosis (CADe/CADx), are being increasingly integrated into endoscopic practice, particularly in areas such as adenoma detection, polyp classification, Barrett's esophagus evaluation, early gastric cancer detection, indeterminate bile duct strictures, and bowel preparation classification. This review explores these key areas and the implications of AI on endoscopic workflows.</p><p>Colorectal cancer (CRC) prevention relies heavily on the detection and removal of adenomatous colon polyps during colonoscopy. AI-powered CADe systems have been developed to enhance adenoma detection rates (ADR) by identifying subtle lesions that may be overlooked by endoscopists. Studies have shown that AI-assisted colonoscopy increases ADR, reduces polyp miss rates, and improves overall procedural quality. By providing real-time visual alerts and bounding boxes around suspected polyps, AI enables more effective and standardized detection.</p><p>Beyond detection, AI plays a critical role in polyp characterization (CADx), aiding endoscopists in distinguishing between neoplastic and non-neoplastic lesions. AI algorithms trained on large datasets of histologically confirmed polyps can provide real-time classification, potentially reducing the need for unnecessary polypectomies. Technologies such as narrow-band imaging (NBI) and confocal laser endomicroscopy, when combined with AI, can enhance the accuracy of in vivo histological assessments. While nearly all polyps in the proximal colon should be removed endoscopically, making pre resection diagnosis less relevant, there remains a value in the rectosigmoid where small hyperplastic polyps can be left in Situ when the endoscopist is confident that they are hyperplastic. Furthermore, large polyps must be stratified into those that are noninvasive, superficially invasive, and deeply invasive to guide therapies such as standard endoscopic mucosal resection, endoscopic submucosal dissection and surgery respectively.</p><p>AI has also been recently shown to facilitate polyps size classification which is notoriously variable and has impact on surveillance recommendations particularly for polyps 10 mm or larger. Having objective measures of size should further standardize surveillance recommendations.</p><p>Barrett's esophagus (BE) is a precursor to esophageal adenocarcinoma, requiring precise surveillance and risk stratification. AI-based systems have been developed to detect BE and its progression to dysplasia by analyzing endoscopic images with high sensitivity and specificity. These algorithms can ","PeriodicalId":159,"journal":{"name":"Digestive Endoscopy","volume":"37 5","pages":"566-568"},"PeriodicalIF":5.0,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/den.15036","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143926144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}