Journal of Glaucoma最新文献

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Treatment Outcomes of Micropulse Transscleral Laser Therapy as an Adjunctive Therapy in African American Individuals With Prior Procedural Interventions. 微脉冲经巩膜激光治疗作为非裔美国人先前手术干预的辅助治疗的治疗结果。
IF 2 4区 医学
Journal of Glaucoma Pub Date : 2025-06-01 Epub Date: 2025-03-04 DOI: 10.1097/IJG.0000000000002559
Anna Dickinson, Luke Leidy, Jella An, Mona Kaleem, Aleksandra Mihailovic, Constance Okeke
{"title":"Treatment Outcomes of Micropulse Transscleral Laser Therapy as an Adjunctive Therapy in African American Individuals With Prior Procedural Interventions.","authors":"Anna Dickinson, Luke Leidy, Jella An, Mona Kaleem, Aleksandra Mihailovic, Constance Okeke","doi":"10.1097/IJG.0000000000002559","DOIUrl":"10.1097/IJG.0000000000002559","url":null,"abstract":"<p><strong>Prcis: </strong>Micropulse transscleral laser therapy is a clinically beneficial adjunctive treatment option for African American individuals with severe-stage primary open angle glaucoma who have undergone prior glaucoma procedural interventions.</p><p><strong>Purpose: </strong>To assess the safety and efficacy of micropulse transscleral laser therapy as an adjunctive treatment in reducing intraocular pressure and ocular hypotensive medications in African American patients.</p><p><strong>Methods: </strong>We analyzed 44 eyes of 44 African American individuals with severe-stage primary open angle glaucoma who underwent prior procedural interventions and received a subsequent micropulse treatment. Mean intraocular pressure and ocular hypotensive medications were evaluated at all postoperative visits through 12 months. Main outcome measures included within-group reductions in intraocular pressure and ocular hypotensive medications at 12 months compared with baseline. Univariate and multivariable logistic regression models were used to calculate odds ratios to evaluate characteristics associated with the likelihood of success at 12 months. Success was defined as achieving a target intraocular pressure of ≤12 mm Hg without additional medications and no secondary surgical interventions.</p><p><strong>Results: </strong>Mean intraocular pressure was significantly reduced from 22.9±6.2 mm Hg at baseline to 13.8±4.8 at 12 months following micropulse, a 40% reduction ( P <0.001). The majority of patients were on 4-6 ocular hypotensive medications at baseline. By 12 months, the proportion of patients requiring ≥3 ocular hypotensive medications was significantly reduced compared with baseline ( P =0.03). Univariate analysis revealed that a history of trabeculectomy before micropulse treatment increased the likelihood of successful surgery at 12 months by nearly 5-fold (OR: 4.67; P =0.03).</p><p><strong>Conclusion: </strong>Micropulse is an effective adjunctive treatment in African Americans with severe-stage primary open angle glaucoma and a history of prior glaucoma procedures.</p>","PeriodicalId":15938,"journal":{"name":"Journal of Glaucoma","volume":" ","pages":"440-446"},"PeriodicalIF":2.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143542236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Anti-Inflammatory Regimen on Selective Laser Trabeculoplasty Outcomes: A Randomized Controlled Trial. 抗炎方案对选择性激光小梁成形术结果的影响:一项随机对照试验。
IF 2 4区 医学
Journal of Glaucoma Pub Date : 2025-06-01 Epub Date: 2025-02-19 DOI: 10.1097/IJG.0000000000002555
Juliana F Miranda, Heloísa A Maestrini, Carolinne C P Barbosa, Laura Oltramari, Guilherme B Guedes, Marcelo M Nascimento, Tiago S Prata, Carla N Urata, Ricardo Y Abe
{"title":"Effect of Anti-Inflammatory Regimen on Selective Laser Trabeculoplasty Outcomes: A Randomized Controlled Trial.","authors":"Juliana F Miranda, Heloísa A Maestrini, Carolinne C P Barbosa, Laura Oltramari, Guilherme B Guedes, Marcelo M Nascimento, Tiago S Prata, Carla N Urata, Ricardo Y Abe","doi":"10.1097/IJG.0000000000002555","DOIUrl":"10.1097/IJG.0000000000002555","url":null,"abstract":"<p><strong>Prcis: </strong>Patients in the prednisolone acetate 1% group post-SLT had higher treatment success rates comparing with other anti-inflammatory drugs.</p><p><strong>Purpose: </strong>To investigate the effect of different anti-inflammatory regimens on selective laser trabeculoplasty (SLT) outcomes.</p><p><strong>Patients and methods: </strong>A prospective randomized controlled trial. We included newly diagnosed primary open angle glaucoma (POAG) patients that underwent a primary SLT session. Patients were randomly divided into 3 groups (prednisolone acetate 1%, prednisolone acetate 0.12%, and ketorolac tromethamine 0.5%). After SLT, intraocular pressure (IOP) data were collected at different time points: days 7 and 30, and at 3, 6, and 12 months post-SLT. The main outcome measure was the comparison of success rates (Kaplan-Meier survival analysis) between groups (log-rank test).</p><p><strong>Results: </strong>We included a total of 134 eyes from 134 newly diagnosed POAG patients (mean age: 62.64±13.86 y) with a mean follow-up of 287±104 days. We observed a significant IOP reduction following SLT treatment in all groups at 12 months (baseline IOP 19.57±3.78 vs. final IOP: 14.39±2.29 mm Hg, P <0.001). Patients in the acetate prednisolone 1% group presented higher survival rates (83.7%) comparing with the other groups (prednisolone acetate 0.12%=63.9%; ketorolac tromethamine 0.5%=67.0%) at 12 months ( P =0.003). Patients in the acetate prednisolone 1% group had higher chances of treatment success [hazard ratio (HR) 0.30; 95% CI: 0.13-0.68, P =0.004], as well as younger patients (HR: 1.03; 95% CI: 1.00-1.05, P =0.005) and those with higher baseline IOP (HR: 0.78; 95% CI: 0.72-0.85 P <0.001). In the multivariable analysis, patients in the acetate prednisolone 1% group remained with higher chances of treatment success (HR: 0.37; 95% CI: 0.15-0.91, P =0.031). No sight-threatening adverse events was reported during follow-up in all groups.</p><p><strong>Conclusions: </strong>In summary, when evaluating the effect of different anti-inflammatory regimens on SLT outcomes in newly diagnosed POAG patients, we found higher success rates in patients treated with prednisolone acetate 1% after SLT. In addition, higher baseline IOP appears to positively influence postoperative outcomes.</p>","PeriodicalId":15938,"journal":{"name":"Journal of Glaucoma","volume":" ","pages":"421-427"},"PeriodicalIF":2.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143440918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Influence of Retinopathy of Prematurity and Laser Therapy on Intraocular Pressure in Preterm Infants. 早产儿视网膜病变及激光治疗对早产儿眼压的影响。
IF 2 4区 医学
Journal of Glaucoma Pub Date : 2025-05-30 DOI: 10.1097/IJG.0000000000002600
Poonam Verma, Deeksha Katoch, Simar Rajan Singh, Praveen Kumar, Ashok Kumar Singh, Faisal Thattaruthody, Surinder Singh Pandav, Sushmita Kaushik
{"title":"Influence of Retinopathy of Prematurity and Laser Therapy on Intraocular Pressure in Preterm Infants.","authors":"Poonam Verma, Deeksha Katoch, Simar Rajan Singh, Praveen Kumar, Ashok Kumar Singh, Faisal Thattaruthody, Surinder Singh Pandav, Sushmita Kaushik","doi":"10.1097/IJG.0000000000002600","DOIUrl":"https://doi.org/10.1097/IJG.0000000000002600","url":null,"abstract":"<p><strong>Precis: </strong>Intraocular pressure (IOP) decreases as preterms mature and in moderate retinopathy of prematurity, IOP is initially low and transiently rises after laser treatment.</p><p><strong>Purpose: </strong>This study aimed to measure intraocular pressure (IOP) in preterm infants with and without retinopathy of prematurity (ROP) and evaluate the effect of laser treatment on IOP.</p><p><strong>Method: </strong>This prospective non-randomized comparative study included infants born before 34 weeks of gestation weighing less than 2000 grams at a tertiary care research and referral institute. Those with ocular or systemic conditions or requiring surgical intervention for ROP were excluded. Infants were divided into three groups: Group 1 (no ROP), Group 2 (ROP without treatment), and Group 3 (ROP requiring peripheral retinal ablation by laser photocoagulation). IOP was measured using a Perkins tonometer at presentation and one and three months. The primary outcome was IOP in preterm infants with and without ROP; and the secondary outcome was change in IOP post-laser treatment.</p><p><strong>Results: </strong>Of 107 infants, 40 (37.38%) had no ROP (Group 1), 25 (23.36%) had untreated ROP (Group 2), and 42 (39.25%) required laser treatment (Group 3). Average post-menstrual ages were 37.89±2.74 weeks 36.98±3.38 and 35.47±2.84 weeks respectively. A moderate negative correlation between IOP and post-menstrual age was found in Group 1 (r2=-0.382; P=0.01) and Group 2 (r2= -0.6; P=0.001). Baseline IOP was significantly lower in Group 3 compared to the other groups, with a transient increase post-laser treatment that typically normalized without needing IOP treatment.</p><p><strong>Conclusions: </strong>IOP decreases as preterm infants mature. Infants with ROP requiring laser treatment exhibit significantly low IOP at presentation, but have a post-laser spike which generally normalises without treatment.</p>","PeriodicalId":15938,"journal":{"name":"Journal of Glaucoma","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144174011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of Standard Automated Visual Field Tests in Glaucoma and the Role of Facial Contour. 青光眼标准自动视野测试分析及面部轮廓的作用。
IF 2 4区 医学
Journal of Glaucoma Pub Date : 2025-05-19 DOI: 10.1097/IJG.0000000000002599
Sepideh Jamali D, Armin Garmany, Tyler M Kaplan, Mostafa Sadegh Mousavi, Helia Ashourizadeh, Zin Tarakji, Cheryl L Khanna
{"title":"Analysis of Standard Automated Visual Field Tests in Glaucoma and the Role of Facial Contour.","authors":"Sepideh Jamali D, Armin Garmany, Tyler M Kaplan, Mostafa Sadegh Mousavi, Helia Ashourizadeh, Zin Tarakji, Cheryl L Khanna","doi":"10.1097/IJG.0000000000002599","DOIUrl":"https://doi.org/10.1097/IJG.0000000000002599","url":null,"abstract":"<p><strong>Prcis: </strong>Using a CNN-enhanced platform, 60-4 visual fields identified peripheral glaucomatous defects missed by central testing in mild cases; facial contour correction showed these defects occurred exclusively outside the temporal visual field.</p><p><strong>Purpose: </strong>To develop a methodology to separate facial contour-induced visual field defects from defects related to glaucoma in patients with peripheral field defects.</p><p><strong>Methods: </strong>Ninety-seven eyes from fifty patients previously diagnosed with glaucoma were enrolled in the study. Thirty-one (62%) participants were male, and 86% were white. The study involved patients with glaucoma who underwent visual field testing using standard automated perimetry, including 10-2, 24-2, 30-2, and 60-4 visual fields. A convolutional neural network (CNN)-enhanced platform, previously developed to identify facial contour-dependent defects in healthy subjects, was used to analyze the visual field data.</p><p><strong>Patients: </strong>The study included ninety-seven eyes from fifty patients with glaucoma, with the majority having primary open angle glaucoma.</p><p><strong>Results: </strong>In ninety out of ninety-seven eyes, there were 60-4 visual field defects. However, 20 (22%) of these eyes did not have glaucomatous defects on the 10-2 or 30-2 visual fields. All patients with 60-4 defects in the absence of more central defects had mild glaucoma, and these eyes comprised 38% of the mild glaucoma group. 60-4 visual field increased the sensitivity of identifying glaucoma in mild disease. Without facial contour, the 60-4 visual field mean threshold summation was 1099.6±346.6 dB, and decreased to 1057±331 dB when accounting for facial contour, which affected 8.03±4.02% of test points. Facial contour-dependent visual field defects were exclusively found outside the temporal visual field.</p><p><strong>Conclusion: </strong>The study demonstrated the potential utility of 60-4 visual fields for identifying early functional glaucomatous changes that may not be detected by more central visual field tests (10-2 or 30-2). It may be important to consider peripheral visual field defects, which can be affected by facial contour, in the diagnosis and monitoring of glaucoma, particularly in mild cases.</p>","PeriodicalId":15938,"journal":{"name":"Journal of Glaucoma","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144078465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical Outcomes of Intraluminal Stent Removal After PAUL® Glaucoma Implant Surgery. PAUL®青光眼植入术后腔内支架移除的临床效果
IF 2 4区 医学
Journal of Glaucoma Pub Date : 2025-05-15 DOI: 10.1097/IJG.0000000000002594
Constance Weber, Diana Samarghitan, Leonie Bourauel, Wolfgang Walz, Sarah Hundertmark, Michael Petrak, Frank G Holz, Karl Mercieca
{"title":"Clinical Outcomes of Intraluminal Stent Removal After PAUL® Glaucoma Implant Surgery.","authors":"Constance Weber, Diana Samarghitan, Leonie Bourauel, Wolfgang Walz, Sarah Hundertmark, Michael Petrak, Frank G Holz, Karl Mercieca","doi":"10.1097/IJG.0000000000002594","DOIUrl":"https://doi.org/10.1097/IJG.0000000000002594","url":null,"abstract":"<p><strong>Precis: </strong>Intraluminal stent-removal post-PGI surgery significantly reduces IOP with high success rates but carries the risk of hypotony and complications, e.g. suprachoroidal hemorrhage. Long-term management often requires the eventual addition of IOP-lowering therapy despite initial efficacy.</p><p><strong>Background: </strong>To report outcomes after intraluminal stent removal following PAUL® Glaucoma Implant (PGI) surgery from a single-center cohort.</p><p><strong>Methods: </strong>Retrospective review of patients undergoing intraluminal prolene removal following PGI surgery at the University Eye Hospital Bonn, Germany, from 04/2021 to 10/2023.</p><p><strong>Results: </strong>70 eyes of 68 patients were included. Qualified and complete success rates (95% CI) were 92.9% and 55.7% after one year and 88.6% (81.4-95.7%) and 50% (37.1-62.9%) at the last follow-up time point for IOP≤18 mmHg and 81.4% and 54.3 and 70% and 42.9% IOP≤15 mmHg, respectively. Mean IOP decreased from 23.93 mmHg to 12.07 mmHg after 12 months, 11.32 mmHg after 24 months and 10.41 mmHg after 36 months. The mean number of IOP-lowering eye drops was zero before and immediately after removal and increased to 1.57 (0-2) at 12 months, 1.15 (0-4) at 24 months and 1.12 (0-4) at 36 months. Postoperative complications occurred in 5 eyes (7.1%). Two eyes had suprachoroidal hemorrhage with one needing vitrectomy and one external tube ligation; one required PGI explantation for persistent hypotony.</p><p><strong>Conclusions: </strong>Removal of the prolene stent following PGI surgery effectively lowers IOP in the short term, with a moderate increase in IOP and need for pressure-lowering therapy over time. However, it can also lead to adverse outcomes, such as hypotony and suprachoroidal hemorrhage, especially in patients with systemic risk factors or those undergoing early removal.</p>","PeriodicalId":15938,"journal":{"name":"Journal of Glaucoma","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144025024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trabeculectomy Bleb Characteristics in Relation to Bleb Success using Anterior Segment Optical Coherence Tomography - A Systematic Review and Meta-Analysis. 小梁切除术泡状泡特征与前段光学相干断层成像泡状泡成功的关系——系统回顾和荟萃分析。
IF 1.8 4区 医学
Journal of Glaucoma Pub Date : 2025-05-15 DOI: 10.1097/IJG.0000000000002595
Jackie Jia Lin Sim, Bjorn Kaijun Betzler, Syril Dorairaj, Tanuj Dada, Bryan Chin Hou Ang
{"title":"Trabeculectomy Bleb Characteristics in Relation to Bleb Success using Anterior Segment Optical Coherence Tomography - A Systematic Review and Meta-Analysis.","authors":"Jackie Jia Lin Sim, Bjorn Kaijun Betzler, Syril Dorairaj, Tanuj Dada, Bryan Chin Hou Ang","doi":"10.1097/IJG.0000000000002595","DOIUrl":"10.1097/IJG.0000000000002595","url":null,"abstract":"<p><strong>Prcis: </strong>ASOCT features of greater bleb height, thicker bleb walls and lower reflectivity are associated with trabeculectomy success, supporting the ASOCT's utility in monitoring and predicting outcomes post-surgery through standardized imaging protocols.</p><p><strong>Purpose: </strong>To evaluate and quantify the relationship between bleb characteristics on ASOCT with surgical outcomes.</p><p><strong>Methods: </strong>Literature search was conducted across Medline, Embase, Cochrane, and Scopus for studies from the past 20 years, until 16 September 2024 on \"glaucoma\", \"trabeculectomy\", and \"ASOCT\". Data collected included patient characteristics, each study's definition of bleb success, clinical outcomes, as well as bleb characteristics. A literature review was conducted on studies which could not be used for meta-analysis.</p><p><strong>Results: </strong>11 studies, with a pooled total of 528 eyes in 517 patients, were included in the final meta-analysis. Successful blebs had significantly higher mean bleb height (mean difference [MD] 0.38 mm, 95%-CI: 0.20-0.56 mm, P=0.002), greater maximum bleb wall thickness (MD 0.21 mm, 95%-CI: 0.07-0.35 mm, P=0.009), and decreased reflectivity (MD -48.9%, 95%-CI: -78.3 to -19.4%, P=0.010), compared to failed blebs. No significant differences were found in bleb fluid cavity height and bleb area. Narrative synthesis revealed that wider blebs, increased fluid-filled cavity height, increased number of microcysts, larger filtration opening widths, and multiform bleb walls were also associated with higher rates of bleb success. Early bleb parameters were statistically significant predictors of bleb success up to 12 months post-operatively.</p><p><strong>Conclusions: </strong>Greater bleb height, thicker bleb walls, and lower reflectivity on ASOCT are consistently associated with successful trabeculectomy outcomes. The ASOCT may be useful in predicting bleb success and in supplementing post-operative monitoring, hence guiding timely medical or procedural interventions, to ensure long-term bleb success.</p>","PeriodicalId":15938,"journal":{"name":"Journal of Glaucoma","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144029184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Aqueous Humor Dynamics Changes and Predictors of IOP Response to Latanoprost in Healthy Subjects. 健康受试者对拉坦前列素IOP反应的房水动力学变化和预测因素。
IF 2 4区 医学
Journal of Glaucoma Pub Date : 2025-05-09 DOI: 10.1097/IJG.0000000000002585
Arash Kazemi, Jeremy C Reitinger, Carol B Toris, Vikas Gulati, Shan Fan, David M Reed, Sayoko E Moroi, Arthur J Sit
{"title":"Aqueous Humor Dynamics Changes and Predictors of IOP Response to Latanoprost in Healthy Subjects.","authors":"Arash Kazemi, Jeremy C Reitinger, Carol B Toris, Vikas Gulati, Shan Fan, David M Reed, Sayoko E Moroi, Arthur J Sit","doi":"10.1097/IJG.0000000000002585","DOIUrl":"https://doi.org/10.1097/IJG.0000000000002585","url":null,"abstract":"<p><strong>Prcis: </strong>In our study of the factors predictive of latanoprost response, we found that normotensive subjects with higher intraocular pressure, lower uveoscleral outflow, and higher body mass index had a greater response to 1-week treatment.</p><p><strong>Purpose: </strong>To evaluate relationships between variable intraocular pressure (IOP) responses to latanoprost and participant characteristics, baseline values and changes in aqueous humor dynamics (AHD) parameters.</p><p><strong>Methods: </strong>We assessed 226 eyes from 113 healthy participants. AHD parameters measured at baseline and after 1-week treatment with latanoprost included: IOP by pneumatonometry, episcleral venous pressure (EVP) by venomanometry, aqueous humor flow rate by fluorophotometry, outflow facility by 2-minute pneumatonography, and uveoscleral outflow calculated using the modified Goldmann equation. IOP responses were categorized into 4 groups: non-responders (<10% reduction), all-responders (≥10% reduction), medium-responders (10-20% reduction), and high-responders (≥20% reduction). Generalized estimating equation models were used to analyze treatment effects and compare groups.</p><p><strong>Results: </strong>Baseline IOP was higher in high-responders than medium-responders and non-responders ( P =0.007 and P <0.001, respectively). Body mass index (BMI) was significantly higher in high-responders and all-responders compared to non-responders ( P =0.02 and P =0.03, respectively). Responders had lower baseline uveoscleral outflow ( P =0.03). There were no significant differences in other baseline characteristics including EVP, outflow facility, and aqueous flow rate between the 4 groups. IOP decreased while outflow facility and uveoscleral outflow increased after latanoprost treatment in all responder groups but did not change in non-responders. EVP and aqueous flow rate did not change significantly in any group. The change in uveoscleral outflow was greater in high-responders than in non-responders ( P =0.004).</p><p><strong>Conclusions: </strong>In healthy subjects, higher baseline IOP, lower uveoscleral outflow and higher BMI are predictors of a greater IOP reduction by latanoprost. A greater increase in uveoscleral outflow is responsible for this larger response.</p>","PeriodicalId":15938,"journal":{"name":"Journal of Glaucoma","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144028384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Accuracy of the Heijl-Krakau Method During Blind-Spot Stimulation With the Head Mounted Imo Perimeter in Patients With Glaucoma and Glaucoma Suspects. 在青光眼和疑似青光眼患者的头戴式Imo周长刺激盲点时Heijl-Krakau方法的准确性。
IF 2 4区 医学
Journal of Glaucoma Pub Date : 2025-05-01 Epub Date: 2025-02-04 DOI: 10.1097/IJG.0000000000002549
Mariko Eura, Hiroki Nomoto, Chota Matsumoto, Takuya Ishibashi, Fumi Tanabe, Keiji Yoshikawa, Mami Nanno, Shunji Kusaka
{"title":"Accuracy of the Heijl-Krakau Method During Blind-Spot Stimulation With the Head Mounted Imo Perimeter in Patients With Glaucoma and Glaucoma Suspects.","authors":"Mariko Eura, Hiroki Nomoto, Chota Matsumoto, Takuya Ishibashi, Fumi Tanabe, Keiji Yoshikawa, Mami Nanno, Shunji Kusaka","doi":"10.1097/IJG.0000000000002549","DOIUrl":"10.1097/IJG.0000000000002549","url":null,"abstract":"<p><strong>Prcis: </strong>13.9% of fixation loss responses by the Heijl-Krakau method were observed even in stable fixation eyes. The Heijl-Krakau method would overestimate the fixation loss responses.</p><p><strong>Purpose: </strong>This study aimed to evaluate the accuracy of the Heijl-Krakau method by measuring eye positions during blind-spot stimulation.</p><p><strong>Methods: </strong>Two thousand one hundred fifty-three eyes of 1155 glaucoma and glaucoma-suspect patients. All patients underwent a head-mounted perimeter imo test. The imo has an eye tracking system that records eye position during tests and assists the device with stimulating corrected points corresponding to eye movement. All stimulus presentations were classified into 3 groups: (1) fixation loss (FL) stimulus: responded to Heijl-Krakau stimuli; (2) non-FL stimulus: did not respond to Heijl-Krakau stimuli; and (3) total stimuli: all other stimuli except for Heijl-Krakau stimuli. We compared the amount of fixation displacement between the FL, non-FL, and total stimuli by the Mann-Whitney U test. Relationships between the FL and mean deviation (MD), the FL and age were analyzed.</p><p><strong>Results: </strong>The median fixation displacements with the FL, non-FL, and total stimuli were 3.2, 1.4, and 1.5 degrees, respectively. The fixation displacement in the FL stimulus group was greater than that in the non-FL and total stimuli groups ( P <0.001). When we defined fixation displacement in the range of <1 degree as \"stable eye fixation,\" 13.9% of the stimulus points corresponded to \"stable eye fixation\" with the FL stimulus. No significant relationships were found in the FL and MD, as well as in the FL and age.</p><p><strong>Conclusion: </strong>In glaucoma and glaucoma suspected patients, after allowance for eye movement by imo patients still responded to the Heijl-Krakau blind spot monitor on 13.9% of occasions. Our results suggest that the Heijl-Krakau method overestimates the FL response in glaucoma and glaucoma suspected patients.</p>","PeriodicalId":15938,"journal":{"name":"Journal of Glaucoma","volume":" ","pages":"400-403"},"PeriodicalIF":2.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143189490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Telemedicine in Glaucoma Management: Patient Perspectives. 远程医疗在青光眼管理:病人的观点。
IF 1.8 4区 医学
Journal of Glaucoma Pub Date : 2025-05-01 Epub Date: 2025-03-04 DOI: 10.1097/IJG.0000000000002558
Angela J Oh, Ella Bouris, Brayden K Leyva, Mashal Malik, Joseph Caprioli
{"title":"Telemedicine in Glaucoma Management: Patient Perspectives.","authors":"Angela J Oh, Ella Bouris, Brayden K Leyva, Mashal Malik, Joseph Caprioli","doi":"10.1097/IJG.0000000000002558","DOIUrl":"10.1097/IJG.0000000000002558","url":null,"abstract":"<p><strong>Prcis: </strong>Patient satisfaction and perspectives on telemedicine for glaucoma are crucial for validating the efficacy of remote health care. This study underscores its acceptance by patients in a single academic practice.</p><p><strong>Purpose: </strong>To evaluate patient satisfaction and preferences with telemedicine visits integrated into a glaucoma practice.</p><p><strong>Methods: </strong>A prospective observational study of patients of a single glaucoma specialist's telemedicine practice was performed using an online questionnaire.</p><p><strong>Results: </strong>Of the 219 patients contacted, 153 (69%, mean age 67.0 y, 58% women) completed the survey. 68% had glaucoma (43% mild, 44% moderate, and 13% severe) and 32% were glaucoma suspects. Patients had been under the care of the specialist for 10±6.2 years, with 41% having undergone surgery with the specialist. The mean number of prior office visits with the specialist was 9.7±6.3 (range 1-24 y) with an average of 0.8 (range 0-3) prior telemedicine visits at the time of the survey. Ninety-seven percent reported satisfaction with integrated telehealth visits, and 78% would recommend telemedicine visits. Ninety-three percent planned to continue with telemedicine; 5 patients (3%) requested switching to in-person only visits with another provider. Compared with their in-person visits, patients found integrated telemedicine visits less time-consuming and more convenient.</p><p><strong>Conclusions: </strong>This study demonstrates high satisfaction and support for integrated telemedicine visits among glaucoma patients within a specialized practice setting.</p>","PeriodicalId":15938,"journal":{"name":"Journal of Glaucoma","volume":" ","pages":"365-370"},"PeriodicalIF":1.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143542235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intraocular Pressure Measurements With the Tono-Vera: A New Handheld Rebound Tonometer. Tono-Vera®眼压测量,一种新的手持式反弹眼压计。
IF 2 4区 医学
Journal of Glaucoma Pub Date : 2025-05-01 Epub Date: 2025-03-04 DOI: 10.1097/IJG.0000000000002556
Luiz A F Beniz, Alessandro A Jammal, Davina A Malek, Henry Tseng, Felipe A Medeiros
{"title":"Intraocular Pressure Measurements With the Tono-Vera: A New Handheld Rebound Tonometer.","authors":"Luiz A F Beniz, Alessandro A Jammal, Davina A Malek, Henry Tseng, Felipe A Medeiros","doi":"10.1097/IJG.0000000000002556","DOIUrl":"10.1097/IJG.0000000000002556","url":null,"abstract":"<p><strong>Prcis: </strong>In a cross-sectional study comparing the novel Tono-Vera handheld rebound tonometer with the Ocular Response Analyzer, a strong agreement was found between the intraocular pressure measurements of the 2 devices.</p><p><strong>Purpose: </strong>To compare intraocular pressure (IOP) measurements obtained by the new Tono-Vera (Reichert Technologies), a novel handheld rebound tonometer with a proprietary camera-based positioning system, with those from the Ocular Response Analyzer (ORA, Reichert Technologies) non-contact tonometer.</p><p><strong>Patients: </strong>Fifty-four eyes of normal individuals and open angle glaucoma subjects.</p><p><strong>Methods: </strong>All subjects had at least 6 reliable measurements with the Tono-Vera and 3 with the ORA, acquired by the same technician in the same visit. The sample was randomly split into calibration and validation samples. An ordinary least squares linear regression model generated a calibration formula for Tono-Vera readings using ORA's Goldmann-correlated IOP (IOPg) as a target. Bland-Altman plots evaluated the agreement between Tono-Vera calibrated IOP (IOPtv) and ORA IOPg in the validation sample.</p><p><strong>Main outcome measures: </strong>Agreement between IOPtv and IOPg measurements.</p><p><strong>Results: </strong>Fifty glaucoma and 4 normal eyes were included, mean age 68.3 ± 9.4 years, mean central corneal thickness 535.0 ± 39.6 μm. In the validation sample, mean IOPtv was 14.6 ± 5.2 mmHg (range, 7.4-28.5 mmHg) versus 15.0 ± 5.3 mmHg (range, 6.6-28.6 mmHg) for ORA IOPg ( R ² = 0.782). Bland-Altman plots showed a mean difference of -0.4 ± 2.5 mmHg (95% limits of agreement: -5.4 to 4.5 mmHg). 58.6%, 79.3%, and 96.5% of IOPtv measurements fell within ± 2, ± 3, and ± 5 mmHg of ORA measurements. No fixed or proportional biases were observed ( P = 0.620).</p><p><strong>Conclusion: </strong>There was a strong correlation and agreement in IOP measurements between calibrated Tono-Vera IOP and ORA IOPg.</p>","PeriodicalId":15938,"journal":{"name":"Journal of Glaucoma","volume":" ","pages":"343-348"},"PeriodicalIF":2.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143542233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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