Journal of Glaucoma最新文献

{"title":"Comparison of Dorzolamide and Netarsudil on Intraocular Pressure and Ocular Perfusion in Early Glaucoma: A Randomized Controlled Trial.","authors":"Vanaja Jain, Dewang Angmo, Gazella Bruce Warjri, Namrata Sharma, Shorya Vardhan Azad, Tanuj Dada","doi":"10.1097/IJG.0000000000002615","DOIUrl":"https://doi.org/10.1097/IJG.0000000000002615","url":null,"abstract":"<p><strong>Precis: </strong>Netarsudil shows promise as a second line drug in early glaucoma patients with an increase in most OCTA parameters as compared to Dorzolamide, with comparable rates of side effects.</p><p><strong>Objective: </strong>To compare the effect of Netarsudil and Dorzolamide on macular and optic nerve head (ONH) perfusion changes on Optical Coherence Tomography Angiography (OCTA), and macular ganglion cell layer (mGCL) and peripapillary retinal nerve fiber layer (pRNFL) thickness on OCT in preperimetric/early glaucoma patients.</p><p><strong>Participants and methods: </strong>In this prospective, randomized, parallel group, active controlled trial 90 preperimetric/early glaucoma eyes were recruited. The primary outcome measure was change in macular and ONH perfusion, and intraocular pressure (IOP). 45 eyes were randomised and prescribed Netarsudil 0.02% (Group 1) and 45 eyes were prescribed Dorzolamide 2% (Group 2). The IOP, ONH perfusion, ONH flux index (FI) and macular vessel density (mVD) on OCTA; pRNFL thickness and mGCL thickness on OCT of the two groups was recorded at baseline, 4 months, 8 months and 12 months.</p><p><strong>Results: </strong>The mean baseline IOP in Group 1 was 19.52±3.2 mmHg and in Group 2 it was 19.5±2.97 mmHg. Group 1 showed 2.77 mmHg (13.23±8.27%) decrease in IOP (P<0.001), while Group 2 showed 1.85 mmHg (8.98±7.32%) decrease in IOP (P<0.001) at 12 months. Group 1 showed 1.58 mm/mm2 increase in mVD (P<0.001), and 0.03 (7.6%) increase in ONH FI (P<0.001) at 12 months. However, no trend in mVD or ONH FI was seen in Group 2. Group 1 showed 1.03% increase in ONH Perfusion (P<0.001) while Group 2 showed 1.16% increase in ONH perfusion (P<0.001). There was no significant difference in ONH perfusion between the two group. The OCT (pRNFL and mGCL) showed normal variability in both the groups. Congestion (40%) was the most common side effect observed in the Netarsudil Group while metallic taste (42.5%) was the most common side effect in the Dorzolamide group. The side effect profile of the two drugs was comparable (P=0.65).</p><p><strong>Conclusion: </strong>Netarsudil causes an increase in all the OCTA parameters - mVD, ONH perfusion, and ONH FI whereas Dorzolamide causes an increase only in ONH perfusion in preperimetric/early glaucoma patients. Netarsudil monotherapy also showed a higher decrease in IOP as compared to dorzolamide therapy.</p>","PeriodicalId":15938,"journal":{"name":"Journal of Glaucoma","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144731737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Visual Field Progression in Glaucoma During COVID-19.","authors":"Bhavini Johri, Lingam Vijaya, Trupti Sudhir Patil, Ronnie George","doi":"10.1097/IJG.0000000000002567","DOIUrl":"10.1097/IJG.0000000000002567","url":null,"abstract":"<p><strong>Prcis: </strong>Visual fields in glaucoma significantly progressed during the COVID-19 pandemic, likely due to reduced compliance and lack of availability of medication.</p><p><strong>Purpose: </strong>To study the impact of the COVID-19 pandemic on the rate of visual field progression in glaucoma and to validate the factors affecting progression.</p><p><strong>Methods: </strong>This hospital-based prospective cohort study included patients diagnosed with primary open angle glaucoma, primary angle closure glaucoma, and ocular hypertension who fulfilled the eligibility criteria. We included 234 eyes with at least 5 reliable Humphrey visual fields (24-2 SITA Standard) before March 24, 2020 and 2 or more after. Glaucoma Progression Analysis software was used to carry out both trend and event-based analysis. Rates of progression prepandemic and postpandemic were compared. Univariate and multivariate logistic regression analyses were done to identify factors affecting progression.</p><p><strong>Results: </strong>The rate of visual field progression increased significantly post lockdown, mean deviation (MD) prelockdown -0.1(SD:0.8) (95% CI: -0.196, 0.001) dB/year versus -0.3 (SD:0.6) (95% CI: -0.362, -0.208) dB/year post lockdown ( P <0.001) and Visual Field Index(VFI) pre lockdown -0.001(SD:0.007) (95% CI: -0.002, 0) %/year versus -0.6 (SD:2.2) (95% CI: -0.903, -0.342) %/year post lockdown ( P <0.001). According to either trend or event analysis, of 234 eyes, 45.3% progressed and 37.6% progressed on any progression post-COVID. The MD of the last field pre-COVID was significantly affecting progression post-COVID based on both trend and event analysis or any progression ( P <0.001).</p><p><strong>Conclusion: </strong>In patients with glaucoma on follow-up, higher rates and proportions of visual field progression were found post the COVID-19 pandemic compared with prepandemic.</p>","PeriodicalId":15938,"journal":{"name":"Journal of Glaucoma","volume":" ","pages":"555-560"},"PeriodicalIF":2.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143604833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"SMOTE-Enhanced Explainable Artificial Intelligence Model for Predicting Visual Field Progression in Myopic Normal Tension Glaucoma.","authors":"So Yeon Kim, Jung Jong Jin, Ahnul Ha, Chae Hyun Song, Se Hie Park, Kyoung Hae Kang, Jaekyoung Lee, Min Gu Huh, Jin Wook Jeoung, Ki Ho Park, Young Kook Kim","doi":"10.1097/IJG.0000000000002579","DOIUrl":"10.1097/IJG.0000000000002579","url":null,"abstract":"<p><strong>Prcis: </strong>The AI model, enhanced by SMOTE to balance data classes, accurately predicted visual field deterioration in patients with myopic normal tension glaucoma. Using SHAP analysis, the key variables driving disease progression were identified.</p><p><strong>Purpose: </strong>To develop and validate a Synthetic Minority Over-sampling Technique (SMOTE)-enhanced artificial intelligence (AI) model for predicting visual field progression in myopic normal tension glaucoma (NTG) patients.</p><p><strong>Methods: </strong>This retrospective cohort study included 100 eyes from myopic NTG patients with a mean follow-up of 10.3±3.2 years. Baseline parameters included intraocular pressure (IOP), central corneal thickness, axial length, and visual field metrics. A SMOTE-enhanced AI model was created to address class imbalance in progression events. Model performance was evaluated using receiver operating characteristic (ROC) analysis, cross-validation, and calibration plots. Predictive factor importance was evaluated through SHapley Additive exPlanations (SHAP) analysis.</p><p><strong>Results: </strong>Visual field progression was observed in 28% of patients, with a median progression time of 3.2 years. The AI model achieved an area under the ROC curve (AUC) of 0.83 (95% CI, 0.75-0.91), with promising sensitivity (0.81) and specificity (0.77). SHAP analysis identified baseline mean deviation (MD), age, axial length, baseline IOP, and visual field index (VFI) as key predictors. When patients were stratified based on model-predicted risk scores, those with scores above 0.8 had significantly higher observed progression rates (82.6%) compared with those with lower risk scores. Subgroup analysis revealed strong correlations between progression risks and older age, greater axial length, and worse baseline MD.</p><p><strong>Conclusions: </strong>The SMOTE-enhanced AI model shows reasonable predictive performance and potential clinical utility for identifying visual field progression in myopic NTG patients, though further validation in larger cohorts is needed. By addressing class imbalance and myopia-specific challenges, this approach enables personalized risk stratification and early intervention.</p>","PeriodicalId":15938,"journal":{"name":"Journal of Glaucoma","volume":" ","pages":"520-527"},"PeriodicalIF":2.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144011316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optical Coherence Tomography Alteration of the Choroid and Lamina Cribrosa in Pseudoexfoliation Syndrome and Glaucoma.","authors":"Sepehr Fekrazad, Mahdi Gouravani, Golnar Hassanzadeh, Asma Mafhoumi, Mina Mirzad, Saeed S Vafa, Benjamin Xu, J Fernando Arevalo","doi":"10.1097/IJG.0000000000002571","DOIUrl":"10.1097/IJG.0000000000002571","url":null,"abstract":"<p><strong>Prcis: </strong>This meta-analysis demonstrates significant thinning of the choroid and lamina cribrosa in eyes with pseudoexfoliation syndrome and pseudoexfoliative glaucoma compared with healthy controls, emphasizing OCT's potential utility for early glaucoma detection in these patients.</p><p><strong>Background: </strong>Pseudoexfoliation syndrome (PXS) is a significant risk factor for pseudoexfoliative glaucoma (PXG), impacting posterior segment tissues such as the choroid and lamina cribrosa (LC). This research aims to investigate the effects of PXS on these layers compared with healthy controls using optical coherence tomography (OCT).</p><p><strong>Methods: </strong>Following the PRISMA checklist, this systematic review, registered at PROSPERO (CRD42023415302), examined OCT measurements in PXS and PXG patients. Searches were conducted in PubMed, Scopus, and EMBASE until April 2023. Selection criteria included human observational studies assessing choroid and lamina cribrosa layers with OCT in PXS and PXG patients. Statistical analyses, including meta-analysis, bias detection, subgroup analysis, and metaregression, were performed.</p><p><strong>Results: </strong>A total of 22 studies, comprising 2293 participants (717 PXG patients, 708 PXS patients, and 868 healthy controls), underwent meta-analysis. In PXG cases, subfoveal choroidal thickness (CT), as well as CT at 1500 µm and 3000 µm temporal and nasal to the fovea, were significantly decreased compared with healthy individuals. In addition, average peripapillary CT and average LCT were significantly reduced in PXG eyes compared with healthy controls. Similarly, eyes with PXS exhibited significantly lower values for subfoveal CT, CT at 1500 µm temporal and 3000 µm nasal to the fovea, average peripapillary CT, and average LC thickness compared with healthy controls.</p><p><strong>Conclusion: </strong>This meta-analysis confirms previously reported decreases in CT and LC thickness in patients with PXG and PXS. Continuous monitoring of choroid and LC using OCT may facilitate the early detection of glaucoma in patients with PXS, addressing a key concern in their management.</p>","PeriodicalId":15938,"journal":{"name":"Journal of Glaucoma","volume":" ","pages":"507-519"},"PeriodicalIF":2.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143700673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Role of Vitreous Zonule Attachments to the Posterior Lens Equator in Primary Angle Closure Glaucoma.","authors":"Jie Huang, Mubin Li, Chukai Huang","doi":"10.1097/IJG.0000000000002577","DOIUrl":"10.1097/IJG.0000000000002577","url":null,"abstract":"<p><strong>Prcis: </strong>Shorter axial length was associated with the absence of the attachments between the posterior insertion zone of the vitreous zonules and the posterior lens equator. Primary angle closure disease eyes without vitreous zonules had a more anteriorly rotated ciliary body.</p><p><strong>Purpose: </strong>To assess the clinical significance of the attachments between the posterior insertion zone of the vitreous zonules and the posterior lens equator (PVZ INS-LE strands) and vitreous zonules (VZ) in primary angle closure disease (PACD).</p><p><strong>Methods: </strong>This cross-sectional study consisted of 90 PACD and 30 cataract eyes from an eye clinic. PVZ INS-LE strands, VZ, and anterior segment parameters were assessed by ultrasound biomicroscopy (UBM). The presence of PVZ INS-LE strands and VZ was compared between groups. Baseline ocular characteristics and UBM parameters were compared among PACD eyes. Factors associated with the absence of PVZ INS-LE strands and VZ were identified.</p><p><strong>Results: </strong>Forty percent of control eyes and 71.1% of PACD showed PVZ INS-LE strands absent. PACD 22.2% and no control eyes showed VZ absent. PVZ INS-LE strands absent group had shorter axial length ( P =0.018), larger ciliary-ciliary angle ( P =0.010), and smaller trabecular-ciliary process distance at 750 μm ( P =0.022). Shorter axial length was independently associated with absence of PVZ INS-LE strands (OR=2.230; 95% CI: 1.027-4.838; P =0.043). VZ absent group had larger ciliary-ciliary angle ( P <0.001), smaller trabecular-ciliary angle ( P =0.040), shorter iris-ciliary process distance at 750 μm ( P =0.092), and shorter trabecular-ciliary process distance at 750 μm ( P =0.026).</p><p><strong>Conclusions: </strong>PVZ INS-LE strands were less likely to be seen in APACD and their fellow eyes. All types of PACD eyes had less presence of VZ. PACD eyes without VZ appeared to have more anterior rotation of the ciliary body. Shorter AL was independently associated with the absence of PVZ INS-LE strands.</p>","PeriodicalId":15938,"journal":{"name":"Journal of Glaucoma","volume":" ","pages":"528-534"},"PeriodicalIF":2.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143988415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gonioscopy-Assisted Transluminal Trabeculotomy in Patients With Angle Recession Glaucoma.","authors":"Enver Mirza, Gunsu D Mirza","doi":"10.1097/IJG.0000000000002568","DOIUrl":"https://doi.org/10.1097/IJG.0000000000002568","url":null,"abstract":"<p><strong>Prcis: </strong>Gonioscopy-assisted transluminal trabeculotomy (GATT) is a successful minimally invasive glaucoma surgery (MIGS) technique for treating patients with angle recession glaucoma (ARG).</p><p><strong>Purpose: </strong>To share 1-year follow-up outcomes of GATT in patients with ARG.</p><p><strong>Patients and methods: </strong>Six eyes of 6 patients with ARG were reviewed in this retrospective study. All of the patients had uncontrolled intraocular pressure (IOP) with antiglaucoma medications (AGM) and a history of blunt ocular trauma (BOT). Preoperative IOP; the number of preoperative AGM; postoperative IOP at first month, third, sixth, and 12th months; postoperative IOP spikes, the need for postoperative AGM, and the need for further surgical interventions were recorded.</p><p><strong>Results: </strong>Five patients underwent GATT and 1 patient underwent GATT combined with phacoemulsification. IOP decreased from 30.30 [7.20] mm Hg preoperatively to 11.95 [3.45] mm Hg postoperatively at the 12th month (P=0.028), with a median difference of -19.50 mm Hg (95% CI: -25.10 to -14.55). After GATT, all patients had varying degrees of hyphema that did not require surgical intervention. IOP peaks were observed in the postoperative first month in 3 patients and IOP was controlled with AGM in these patients. The median (IQR) preoperative number of AGM decreased significantly compared with the median (IQR) postoperative number of AGM at the 12th month [P=0.038, 4.00 (0.25) vs. 2.00 (1.25), median difference: -1.50, 95% CI: -2.00 to -0.50]. During the 1-year follow-up, no patients with ARG required additional surgical intervention.</p><p><strong>Conclusion: </strong>Due to its low complication rates and successful IOP-lowering effect, we recommended that GATT is an effective, safe, and considerable MIGS procedure for patients with ARG.</p>","PeriodicalId":15938,"journal":{"name":"Journal of Glaucoma","volume":"34 7","pages":"535-540"},"PeriodicalIF":2.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144497229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Staphylococcus Capitus Blebitis Following Preserflo MicroShunt Implantation.","authors":"Bachar Kudsieh, Elena Almazan-Alonso, Jorge Ruiz-Medrano, Muhsen Samaan, Jose Maria Ruiz-Moreno","doi":"10.1097/IJG.0000000000002578","DOIUrl":"10.1097/IJG.0000000000002578","url":null,"abstract":"<p><strong>Purpose: </strong>To report a case of early-onset blebitis following Preserflo MicroShunt implantation.</p><p><strong>Patients and methods: </strong>Case report.</p><p><strong>Results: </strong>A 73-year-old woman with a history of open angle glaucoma secondary to pseudoexfoliative syndrome in her right eye underwent Preserflo MicroShunt implantation augmented with mitomycin C. Three months postoperatively, she experienced ocular pain and a decrease in visual acuity. Clinical examination revealed conjunctival hyperemia surrounding a whitish filtering bleb, positive conjunctival fluorescein staining, and a positive Seidel sign leading to hypotony. In addition, an inflammatory reaction was observed in the anterior chamber, along with localized vitreous haze. Management included topical antibiotic therapy, removal of necrotic tissue, and explantation of the Preserflo MicroShunt. Staphylococcus capitis was isolated from both conjunctival and implant cultures, confirming the clinical diagnosis of infectious blebitis. Intraocular pressure and visual function were successfully restored after surgery.</p><p><strong>Conclusions: </strong>Blebitis is a rare but potentially serious complication following Preserflo MicroShunt implantation with mitomycin C. Device removal may be necessary to prevent bacterial infection from extending beyond the filtering bleb into the anterior chamber.</p>","PeriodicalId":15938,"journal":{"name":"Journal of Glaucoma","volume":" ","pages":"e38-e40"},"PeriodicalIF":2.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144029379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing Vascular and Structural Hemiretinal Asymmetry at Different Stages of Normal Tension Glaucoma Using Optical Coherence Tomography.","authors":"Xiaonan Lu, De-Fu Chen, Chenmin Wang, Jinrui Zhang, Tao Wang, Cong Zhang, Qiangjie Huang, Yuanbo Liang","doi":"10.1097/IJG.0000000000002572","DOIUrl":"10.1097/IJG.0000000000002572","url":null,"abstract":"<p><strong>Prcis: </strong>Hemiretinal asymmetry in different stages of normal tension glaucoma (NTG) may be helpful in diagnosis and staging.</p><p><strong>Purpose: </strong>To investigate hemiretinal asymmetry in peripapillary capillary vessel density (pcVD), macular vessel density (macVD), circumpapillary retinal nerve fibre layer (RNFL) thickness, and macular ganglion cell-inner plexiform layer (GCIPL) across various stages of normal tension glaucoma (NTG) and determine its potential as a staging tool.</p><p><strong>Subjects and methods: </strong>A total of 199 subjects were included, categorized into the preperimetric, early, moderate, and advanced stage based on mean deviation (MD). Vessel density was measured using optical coherence tomography angiography, while peripapillary RNFL and macular GCIPL thickness were assessed with spectral-domain optical coherence tomography scans. The asymmetry parameter was defined as the absolute difference between superior and inferior values in the same eye. We analysed the characteristics of these parameters across glaucoma stages and evaluated the distribution of structural damage among the groups.</p><p><strong>Results: </strong>Hemiretinal asymmetry parameters showed significant statistical differences across the 4 groups, following a trend of moderate > early > late > preperimetric stages. Furthermore, hemiretinal difference in pcVD (hd pcVD) ( P= 0.009) and hemiretinal difference in RNFL (hd RNFL) ( P= 0.003) have statistical differences between preperimetric and early stage. Besides, 50% to 80% of the participants in each stage exhibited smaller structural parameters in the inferior hemisphere.</p><p><strong>Conclusions: </strong>The hemiretinal asymmetry parameter exhibits a clear trend across different stages of NTG, aiding in the staging of NTG before reaching the moderate stage. Furthermore, it has advantages in differentiating between the preperimetric and early stages. In addition, the intraocular inferior hemisphere structure damage is more severe.</p>","PeriodicalId":15938,"journal":{"name":"Journal of Glaucoma","volume":" ","pages":"541-548"},"PeriodicalIF":2.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143700669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hemorrhagic Descemet's Membrane Detachment After Gonioscopy-Assisted Transluminal Trabeculotomy.","authors":"Gunsu D Mirza, Enver Mirza","doi":"10.1097/IJG.0000000000002551","DOIUrl":"10.1097/IJG.0000000000002551","url":null,"abstract":"<p><strong>Purpose: </strong>To report a rare case of hemorrhagic Descemet's membrane detachment (DMD) after gonioscopy-assisted transluminal trabeculotomy (GATT) and to discuss its management.</p><p><strong>Methods: </strong>A 71-year-old male patient with advanced pseudoexfoliation glaucoma and dense cataract was planned to perform combined GATT and cataract extraction. DMD was noticed after blood reflux from Schlemm canal during GATT. Circumferential ab-interno trabeculotomy was completed and DMD was reattached with air tamponade. Cataract extraction was postponed to prevent the progression of DMD.</p><p><strong>Results: </strong>Hemorrhagic DMD was monitored during a 3-month follow-up. Spontaneous resorption was not observed. A side port incision was made at the site of hemorrhagic DMD during cataract extraction. The space upon DM was washed out with a balanced salt solution to allow drainage of the hemorrhage and an air bubble was left in the anterior chamber. On the first postoperative day after cataract extraction, DM was observed to be attached and the hemorrhage had disappeared completely.</p><p><strong>Conclusions: </strong>Hemorrhagic DMD is an unusual complication after GATT and it may be challenging to manage. Surgeons who perform GATT should be aware of this rare corneal complication.</p>","PeriodicalId":15938,"journal":{"name":"Journal of Glaucoma","volume":" ","pages":"e34-e37"},"PeriodicalIF":2.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143382652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Screening of Glaucoma in High-Risk Minority Populations.","authors":"Nariman Nassiri, M Roy Wilson","doi":"10.1097/IJG.0000000000002581","DOIUrl":"10.1097/IJG.0000000000002581","url":null,"abstract":"<p><strong>Precis: </strong>This chapter reviews the current recommendations on screening for open angle glaucoma in Black and Hispanic populations. Strategies for increasing case-finding and decreasing cost, with emphasis on evolving technologies, are presented.</p><p><strong>Purpose: </strong>To address the current recommendations on primary open angle glaucoma screening in high-risk minority populations and to discuss potential strategies to improve the screening of glaucoma in these populations.</p><p><strong>Methods: </strong>A literature review was performed by searching PubMed, EMBASE, and Google Scholar. All English-language papers that resulted from the search terms from January 1980 to October 2023 were reviewed.</p><p><strong>Results: </strong>In the next few decades, the societal burden of glaucoma will increase because of the demographic shift to an older and more diverse US population, including Black and Hispanic populations, which have been shown to have a higher prevalence of the disease. The current (2022) conclusion of the US Preventive Services Task Force is that the evidence to assess the balance of benefits and harms of screening for glaucoma in adults is insufficient to recommend widespread screening. The Preferred Practice Pattern guideline similarly states that screening for glaucoma in the general population is not cost-effective. However, the guidelines state that screening is more useful and cost-effective when it is targeted at populations at high risk for glaucoma, such as older adults, those with a family history of glaucoma, and Black and Hispanic individuals. Strategies for improving the effectiveness of glaucoma screening must increase case finding and decrease cost. New screening technologies, such as telemedicine and artificial intelligence, are expanding access for underserved populations.</p><p><strong>Conclusions: </strong>There is still no clear consensus on the effectiveness of glaucoma screening for the general population. However, glaucoma screening may be useful and cost-effective when it is targeted at populations at high risk for glaucoma, particularly using emerging technologies that improve access and case-finding.</p>","PeriodicalId":15938,"journal":{"name":"Journal of Glaucoma","volume":"34 7","pages":"561-564"},"PeriodicalIF":2.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144497230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}