Journal of Glaucoma最新文献

{"title":"Socioeconomic and Racial Disparities in Primary Open Angle Glaucoma in the United States.","authors":"Carolyn S Downs, Paul J Percelay, Brandon Williams, Patricia J Goedecke, Jess M Wesberry, Nawajes Mandal","doi":"10.1097/IJG.0000000000002513","DOIUrl":"10.1097/IJG.0000000000002513","url":null,"abstract":"<p><strong>Prcis: </strong>Socioeconomic status is a potentially significant, although difficult to isolate, factor in determining glaucoma severity.</p><p><strong>Purpose: </strong>To analyze the level of glaucoma severity (mild, moderate, or severe) based on demographic factors, including age, gender, ethnicity, insurance profile, and zip code, and to use this data to extrapolate the effect of socioeconomic status (SES) and race on glaucoma severity at the community level in Memphis, TN.</p><p><strong>Patients and methods: </strong>Totally, 2913 patients from a tertiary care center with 3 clinic locations in Memphis, TN who had been given the diagnosis of primary open angle glaucoma (POAG) through use of the ICD-10 codes for mild (H40.1111, H40.1121, H40.1131), moderate (H40.1112, H40.1122, H40.1132), and severe (H40.1113, H40.1123, H40.1133) POAG between January 2016 and July 2021 were included in this study. Diagnoses were made after a complete glaucoma workup consisting of Snellen visual acuity, applanation IOP measurement, gonioscopy, automated Humphreys visual fields (10-2 and 24-2), and optic nerve OCT. Demographic information, including age, gender, ethnicity, insurance profile, and zip code, was also collected with disease severity for each patient. SES was approximated using zip code-level census poverty data and insurance profiles. Statistical analyses were performed, including descriptive, multivariable ordinal logistic modeling, and stepwise multivariable linear modeling.</p><p><strong>Results: </strong>Glaucoma severity was shown to increase with poverty rate (OR=1.089, P <0.0071), age (OR=1.030, P <0.0001), male sex (OR=1.374, P <0.0001), and Black race (OR=1.896, P <0.0001). Severity was shown to be decreased in patients with private insurance compared with Medicare (OR=0.895, P <0.093) and those from Shelby County compared with other counties (OR=0.703, P <0.0001).</p><p><strong>Conclusions: </strong>Our findings indicate that worsening glaucoma severity was associated with higher poverty rates in our patient population. However, isolating socioeconomic status (SES) as an independent factor influencing the incidence and severity of glaucoma remains challenging, given the strong correlation between race and SES.</p>","PeriodicalId":15938,"journal":{"name":"Journal of Glaucoma","volume":" ","pages":"157-163"},"PeriodicalIF":2.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142501981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optical Coherence Tomography Angiography Analysis of Peripapillary Choroidal Microvascular Density in Normal Tension Glaucoma and Primary Open Angle Glaucoma.","authors":"Yongdong Lin, Hongxi Wang, Shirong Chen, Kailin Xiao, Xujia Liu, Xiaolin Xie, Xin Zheng, Li Tan, Di Ma","doi":"10.1097/IJG.0000000000002499","DOIUrl":"10.1097/IJG.0000000000002499","url":null,"abstract":"<p><strong>Prcis: </strong>Glaucoma patients had a reduction in the inner annulus peripapillary choroidal microvascular density (PCMD) that became worse as the glaucoma severity progressed, which might provide new evidence supporting the vascular theory.</p><p><strong>Purpose: </strong>To compare PCMD among normal tension glaucoma (NTG), primary open angle glaucoma (POAG), and healthy controls using optical coherence tomography (OCT) angiography (OCTA).</p><p><strong>Materials and methods: </strong>The study included 40 POAG, 25 NTG, and 33 healthy controls. All subjects underwent OCT and OCTA testing. The inner annulus and outer annulus PCMD, as well as peripapillary vessel density (VD), were calculated. One-way analysis of variance was used to compare the vascular parameters of the 3 groups. Pearson correlation analysis or Spearman correlation test was used to evaluate the correlation between PCMD and glaucomatous severity factors. The spatial positional relationship between PCMD and corresponding peripapillary retinal nerve fiber layer (RNFL) thickness and visual field (VF) mean deviation (MD) was also assessed.</p><p><strong>Results: </strong>The average and 4 quadrants of the inner annulus PCMD and peripapillary VD in the 2 glaucomatous groups were significantly lower than in normal eyes ( P <0.05). Strong correlations were found between inner annulus PCMD and VF MD, peripapillary VD, and RNFL in POAG patients. Similarly, the inner annulus PCMD in NTG patients was strongly correlated with peripapillary VD and RNFL (all r >0.5). Strong positional correlations were found between inner superior quadrantal PCMD and RNFL thickness in both POAG and NTG patients ( r =0.566 and 0.731, respectively). Likewise, inner inferior quadrantal PCMD exhibited a strong correlation with RNFL thickness in POAG patients ( r =0.608). Strong positional correlations were also found between inner superior PCMD and VF MD in both POAG and NTG patients ( r =0.589 and 0.622, respectively). Inner inferior PCMD exhibited a moderate correlation with VF MD in both POAG and NTG patients ( r =0.487 and 0.440, respectively).</p><p><strong>Conclusion: </strong>The study found that the inner annulus PCMD decreased to varying degrees in NTG and POAG patients. The inner annulus PCMD was closely related to the structural and visual function parameters of glaucoma in both NTG and POAG. Furthermore, inner PCMD demonstrated a spatial correlation with corresponding RNFL thickness and VF MD.</p>","PeriodicalId":15938,"journal":{"name":"Journal of Glaucoma","volume":" ","pages":"189-197"},"PeriodicalIF":2.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142307904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Guardian Knowledge in Primary Congenital Glaucoma.","authors":"Ahmad Samir Alfaar, Doaa M Hassan, Mohammed Bawazir, Zeinab Elsanabary, Sameera Ezzat, Yasmine Elsayed","doi":"10.1097/IJG.0000000000002517","DOIUrl":"10.1097/IJG.0000000000002517","url":null,"abstract":"<p><strong>Prcis: </strong>Guardian education level and frequency of surgical interventions are key determinants of knowledge in primary congenital glaucoma, highlighting the need for targeted educational strategies.</p><p><strong>Objective: </strong>Management of congenital glaucoma poses unique challenges, particularly concerning the patient guardians' understanding of the condition, which is crucial for treatment adherence and follow-up compliance. This study aimed to assess guardians' knowledge levels and identify the influencing factors.</p><p><strong>Methods: </strong>This cross-sectional study included 103 guardians of pediatric patients with primary congenital glaucoma. Participants with missing data were excluded from the study. The participants were assessed using a 20-question survey covering various aspects of glaucoma. Descriptive and inferential statistics were used for analysis.</p><p><strong>Results: </strong>The sample included 96 guardians, primarily females (80.2%). The children's ages varied significantly, averaging ∼44 months (SD = 39.8). The guardians predominantly had secondary education (34.4%) and most were housewives (77.1%). There was a positive correlation between higher education levels and the overall knowledge score of guardians ( P = 0.006). Similarly, the guardian's locality showed a positive correlation with knowledge scores, with urban guardians having higher scores than rural guardians. In addition, there was a positive correlation between the number of surgical operations performed on the child and the guardians' knowledge. For the subtotals, variables such as the child order among siblings and the age of the child showed significant positive correlations, emphasizing the multifaceted influences on guardians' understanding. In the multivariate analysis, the guardian's education level showed a significant positive correlation with the overall score, as did the number of operations performed on the patient.</p><p><strong>Conclusions: </strong>The study revealed gaps in guardian knowledge, irrespective of educational level or other demographic factors. Guardians' education level and the number of operations performed on the child are critical determinants of guardians' understanding of congenital glaucoma. Traditional approaches to educational interventions may require reevaluation, and there is a pressing need for targeted educational interventions.</p>","PeriodicalId":15938,"journal":{"name":"Journal of Glaucoma","volume":" ","pages":"216-223"},"PeriodicalIF":2.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142962152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optical Microangiography and Progressive Retinal Nerve Fiber Layer Loss in Primary Angle Closure Glaucoma.","authors":"Harsha L Rao, Srilakshmi Dasari, Narendra K Puttaiah, Zia S Pradhan, Sasan Moghimi, Kaweh Mansouri, Carroll A B Webers, Robert N Weinreb","doi":"10.1097/IJG.0000000000002524","DOIUrl":"10.1097/IJG.0000000000002524","url":null,"abstract":"<p><strong>Prcis: </strong>Younger patient age (coefficient: 0.10, P =0.04) and greater peak IOP during follow-up (coefficient: -0.14, P =0.03), but not baseline optical microangiography parameters, were significantly associated with a faster rate of RNFL loss in mild-moderate PACG.</p><p><strong>Purpose: </strong>To evaluate the association between optical microangiography (OMAG) measurements and progressive retinal nerve fiber layer (RNFL) loss in primary angle closure glaucoma (PACG).</p><p><strong>Methods: </strong>In a prospective study, 45 eyes of 30 PACG patients (86 hemifields) with mild to moderate functional damage were longitudinally studied for at least 2 years and with a minimum of 3 optical coherence tomography (OCT) examinations. OMAG imaging was performed at the baseline visit. Effect of clinical parameters (age, sex, presence of systemic diseases, central corneal thickness, mean, peak, and fluctuation of intraocular pressure during follow-up), baseline hemifield mean deviation (MD) and baseline OMAG [quadrant peripapillary and macular perfusion density(PD)] on the rate of RNFL change was evaluated using linear mixed models.</p><p><strong>Results: </strong>The average (±SD) hemifield MD, RNFL thickness, peripapillary PD and macular PD of the analyzed quadrants at baseline were -6.0±3.4 dB, 89±21 µm, 40.1±3.5%, and 29.6±10.3%, respectively. The rate of quadrant RNFL change was -2.5±1.7 µm/year. Multivariate mixed models showed that younger patient age (coefficient: 0.10, P =0.04) and higher peak IOP during follow-up (coefficient: -0.14, P =0.03) were significantly associated with a faster rate of RNFL loss.</p><p><strong>Conclusions: </strong>Younger patient age and greater peak IOP during follow-up were significantly associated with a faster rate of RNFL loss in PACG patients with mild to moderate severity of functional damage. None of the OMAG parameters at baseline were associated with RNFL thinning suggesting a limited role of OCTA imaging in predicting structural progression in mild-moderate PACG.</p>","PeriodicalId":15938,"journal":{"name":"Journal of Glaucoma","volume":"34 3","pages":"175-181"},"PeriodicalIF":2.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143501768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Peripapillary Arterial Circle of Zinn-Haller With Glaucoma in Highly Myopic Eyes.","authors":"Ji Hong Kim, Jooyoung Yoon, Kyeong Ik Na, Rim Kyung Hong, Won June Lee","doi":"10.1097/IJG.0000000000002514","DOIUrl":"10.1097/IJG.0000000000002514","url":null,"abstract":"<p><strong>Prcis: </strong>The visualization of circle of Zinn-Haller (CZH) on optical coherence tomography angiography (OCTA) or its pattern does not have a clear effect on glaucoma, whereas the location of CZH is associated with axial length (AXL) in highly myopic eyes.</p><p><strong>Purpose: </strong>To investigate the association between the CZH and the presence of glaucoma using swept-source optical coherence tomography angiography (SS-OCTA) images of the optic nerve of patients with high myopia (HM).</p><p><strong>Methods: </strong>This retrospective case series included 227 eyes with HM, comprising 134 and 93 eyes with and without glaucoma, respectively. The characteristics of CZH, including visualization, pattern, and location, were assessed using SS-OCTA. Vascular parameters, such as vessel density and microvascular dropout (MvD), were quantified. The factors affecting the presence of glaucoma and the correlations between the CZH distance and AXL were identified using logistic regression analysis and Pearson correlation analysis, respectively.</p><p><strong>Results: </strong>CZH was detected more frequently in HM patients with glaucoma (71.6%) than in patients without glaucoma (51.6%) ( P <0.002). However, the visualization of CZH was not related to the presence of glaucoma in multivariate regression analysis (odds ratio [OR], 0.688; 95% confidence interval [CI], 0.328-1.444; P =0.322). Moreover, compared with the annular pattern used as a reference, triangular and irregular patterns were not associated with the presence of glaucoma (OR: 1.043, 95% CI: 0.101-10.763, P =0.971; OR: 0.527, 95% CI: 0.255-1.092, P =0.085, respectively). MvD was significantly higher in patients with glaucoma (61.2%) than that in patients without glaucoma (2.2%) ( P <0.001) and was identified as a significant factor affecting the presence of glaucoma (OR, 42.120; 95% CI, 9.416-188.413; P <0.001). AXL showed a significant correlation with CZH distance in all patients (R=0.399; P <0.001).</p><p><strong>Conclusions: </strong>CZH was more commonly detected in HM patients with glaucoma. However, no clear associations of glaucoma with the visualization, pattern, or location of CZH were observed in the present study. The correlation between AXL and CZH distance in eyes with HM warrants further investigation. These results may offer insights into the pathogenesis of glaucoma in eyes with HM as OCTA technology advances.</p>","PeriodicalId":15938,"journal":{"name":"Journal of Glaucoma","volume":" ","pages":"205-215"},"PeriodicalIF":2.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142522062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Anti-Inflammatory Regimen on Selective Laser Trabeculoplasty Outcomes: A Randomized Controlled Trial.","authors":"Juliana F Miranda, Heloísa A Maestrini, Carolinne C P Barbosa, Laura Oltramari, Guilherme B Guedes, Marcelo M Nascimento, Tiago S Prata, Carla N Urata, Ricardo Y Abe","doi":"10.1097/IJG.0000000000002555","DOIUrl":"https://doi.org/10.1097/IJG.0000000000002555","url":null,"abstract":"<p><strong>Precis: </strong>Patients in the prednisolone acetate 1% group post-SLT had higher treatment success rates comparing to other anti-inflammatory drugs.</p><p><strong>Purpose: </strong>To investigate the effect of different anti-inflammatory regimens on selective laser trabeculoplasty (SLT) outcomes.</p><p><strong>Patients and methods: </strong>Prospective randomized controlled trial. We included newly diagnosed primary open angle glaucoma (POAG) patients that underwent a primary SLT session. Patients were randomly divided into 3 groups (prednisolone acetate 1%, prednisolone acetate 0.12% and ketorolac tromethamine 0.5%). After SLT, intraocular pressure (IOP) data were collected at different time points: days 7 and 30, and at 3, 6 and 12 months post-SLT. Main outcome measure was the comparison of success rates (Kaplan Meier survival analysis) between groups (log-rank test).</p><p><strong>Results: </strong>We included a total of 134 eyes from 134 newly diagnosed POAG patients (mean age: 62.64±13.86 y) with a mean follow-up of 287±104 days. We observed a significant IOP reduction following SLT treatment in all groups at 12 months (baseline IOP 19.57±3.78 vs. final IOP: 14.39±2.29 mmHg, P<0.001). Patients in the acetate prednisolone 1% group presented higher survival rates (83.7%) comparing to the other groups (prednisolone acetate 0.12%=63.9%; ketorolac tromethamine 0.5%=67.0%) at 12 months (P=0.003). Patients in the acetate prednisolone 1% group had higher chances of treatment success (hazard ratio [HR] 0.30; 95% CI: 0.13-0.68, P=0.004), as well as younger patients (HR 1.03; 95% CI: 1.00-1.05, P=0.005) and those with higher baseline IOP (HR 0.78; 95% CI: 0.72-0.85 P<0.001). In the multivariable analysis, patients in the acetate prednisolone 1% group remained with higher chances of treatment success (HR 0.37; 95% CI: 0.15-0.91, P=0.031). No sight-threatening adverse events was reported during follow-up in all groups.</p><p><strong>Conclusions: </strong>In summary, evaluating the effect of different anti-inflammatory regimens on SLT outcomes in newly diagnosed POAG patients, we found had higher success rates in patients treated with prednisolone acetate 1% after SLT. In addition, higher baseline IOP seem to positively influence post-operative outcomes.</p>","PeriodicalId":15938,"journal":{"name":"Journal of Glaucoma","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143440918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between Central Corneal Thickness and Inter-eye Disease Severity in Primary Angle Closure Glaucoma.","authors":"Shimna C Prasad, Ruthra M Umapathi, Tin Nwe Hlaing, Eray Atalay, Michael J Girard, Tin Aung, Monisha E Nongpiur","doi":"10.1097/IJG.0000000000002553","DOIUrl":"https://doi.org/10.1097/IJG.0000000000002553","url":null,"abstract":"<p><strong>Precis: </strong>Inter-ocular comparison of primary angle closure glaucoma subjects with asymmetrical and symmetrical visual field loss, revealed significantly thinner central corneal thickness and higher presenting intraocular pressure in the worse eye of the asymmetrical group.</p><p><strong>Purpose: </strong>To compare the inter-ocular clinical and biometric parameters of primary angle-closure glaucoma (PACG) with asymmetrical and symmetrical visual-field loss at presentation.</p><p><strong>Patient and methods: </strong>Retrospective study in which the following clinical data were extracted: presenting intraocular pressure (IOP), gonioscopy, visual-field mean deviation (MD), central corneal thickness (CCT), anterior chamber depth (ACD) and axial length (AL). Asymmetrical PACG was defined as the inter-eye visual-field MD difference >6 dB, symmetrical PACG <3 dB, and those with inter-eye difference between 3-6 dB were excluded. Linear mixed effects model was used to adjust for the interdependence of the right and left eyes.</p><p><strong>Results: </strong>Of 243 PACG subjects, 122 (50.3%) presented with asymmetrical, and 69 (28.4%) with symmetrical disease. The worse eyes in subjects with asymmetrical PACG had significantly higher presenting IOP (P<0.001), narrower angles (P<0.001), more myopic refraction (P<0.001) and thinner CCT (529.2±36.1 μm vs. 535.8±38.5 μm; P<0.001) compared to the fellow eyes; but no inter-eye differences were observed for AL (P=0.93) and ACD (P=0.53). In symmetric PACG, no significant inter-eye differences were observed for CCT (532.3±33.1 vs. 533.1±34.6 μm, P=0.67), AL (P=0.85) and ACD (P=0.18), but the relatively worse eye had higher presenting IOP (P=0.003). In the stepwise multiple linear regression analysis in the asymmetrical group, CCT was the only significant variable (P=0.006), explaining 12% of the variability of the visual-field MD of the worse eye.</p><p><strong>Conclusions: </strong>In asymmetrical PACG, worse eyes have thinner CCT and higher presenting IOP. Difference in CCT could either be inherent or acquired, and more tests would be needed to tease that out.</p>","PeriodicalId":15938,"journal":{"name":"Journal of Glaucoma","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143408623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hemorrhagic Descemet Membrane Detachment after Gonioscopy-Assisted Transluminal Trabeculotomy.","authors":"Gunsu Deniz Mirza, Enver Mirza","doi":"10.1097/IJG.0000000000002551","DOIUrl":"https://doi.org/10.1097/IJG.0000000000002551","url":null,"abstract":"<p><strong>Purpose: </strong>To report a rare case of hemorrhagic Descemet membrane detachment (DMD) after Gonioscopy-Assisted Transluminal Trabeculotomy (GATT) and to discuss its management.</p><p><strong>Methods: </strong>A 71-year-old male patient with advanced pseudoexfoliation glaucoma and dense cataract was planned to perform combined GATT and cataract extraction. DMD was noticed after blood reflux from Schlemm's canal during GATT. Circumferential ab-interno trabeculotomy was completed and DMD was reattached with air tamponade. Cataract extraction was postponed to prevent progression of DMD.</p><p><strong>Results: </strong>Hemorrhagic DMD was monitored during a 3-month follow-up. Spontaneous resorption was not observed. A side port incision was made at the site of hemorrhagic DMD during cataract extraction. The space upon DM was washed out with a balanced salt solution to allow drainage of the hemorrhage and an air bubble was left in the anterior chamber. On the first postoperative day after cataract extraction, DM was observed to be attached and the hemorrhage had disappeared completely.</p><p><strong>Conclusions: </strong>Hemorrhagic DMD is an unusual complication after GATT and it may be challenging to manage. Surgeons who perform GATT should be aware of this rare corneal complication.</p>","PeriodicalId":15938,"journal":{"name":"Journal of Glaucoma","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143382652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association Between Sociodemographic Risk Factors and No-Show Propensity in a Glaucoma Population Before and During Covid-19 Pandemic.","authors":"Amey Kamdar, Gelila B Yohannes, Swarup S Swaminathan","doi":"10.1097/IJG.0000000000002550","DOIUrl":"https://doi.org/10.1097/IJG.0000000000002550","url":null,"abstract":"<p><strong>Prcis: </strong>Greater social vulnerability, younger age, non-white race, Hispanic ethnicity, non-English speaking, Medicaid insurance, and milder glaucoma were associated with higher no-show propensity, which worsened during the Covid-19 pandemic among those subjects who were older and more socially vulnerable.</p><p><strong>Purpose: </strong>To identify sociodemographic risk factors for higher likelihood to no-show among glaucoma subjects before and during the Covid-19 pandemic using the no-show propensity factor (NSPF), a novel attendance metric, which improves upon no-show percentages by adjusting for number of visits.</p><p><strong>Methods: </strong>We analyzed de-identified demographic, visit attendance, and social risk factor data (social vulnerability index (SVI) and area deprivation index (ADI) scores) of de-identified glaucoma subjects from the Bascom Palmer Glaucoma Repository, computed NSPF, and categorized scores as low, intermediate, or high by the 75th and 90th percentiles for the pre-pandemic and pandemic periods. We identified predictors of NSPF scores using univariable, multivariable, and logistic regression analyses.</p><p><strong>Results: </strong>Of 15,342 subjects, 11,474, 2,238, and 1,630 subjects had low, intermediate, and high NSPF scores respectively with no-show rates of 9.5%, 39.2%, and 57.8% respectively. Age (β=-0.039 per decade, P<0.001), Black race (β=0.152, P<0.001), Hispanic ethnicity (β=0.115, P<0.001), Medicaid (β=0.073, P<0.001), Spanish primary language (β=0.076, P<0.001), SVI scores (β=0.047 per 25% increase, P<0.001), ADI ranking (β=0.057 for highest quartile, P<0.001), and baseline moderate (β=-0.046, P<0.001) or severe (β=-0.077, P<0.001) glaucomatous disease were significant predictors of NSPF. Older age (odds ratio (OR) 1.15 per decade, P<0.001), higher overall SVI (OR 1.09 per 25% increase, P<0.001), Medicare/Tricare insurance (OR 1.13, P=0.044), and non-English/Spanish primary language (OR 1.43, P=0.020) were associated with worsening NSPF during the pandemic.</p><p><strong>Conclusion: </strong>Younger age, non-white race, Hispanic ethnicity, non-English primary language, Medicaid, milder glaucoma, and residence in vulnerable areas are risk factors for greater propensity to no-show.</p>","PeriodicalId":15938,"journal":{"name":"Journal of Glaucoma","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143382651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the Long-Term Effects of Selective Laser Trabeculoplasty on Patients with Primary Open Angle Glaucoma.","authors":"Michele Lanza, Luigi Serra, Rosa Boccia, Teresa Cangiano, Maria Coniglio, Italo Fattore, Francesca Simonelli","doi":"10.1097/IJG.0000000000002547","DOIUrl":"https://doi.org/10.1097/IJG.0000000000002547","url":null,"abstract":"<p><strong>Precis: </strong>Data coming from this study suggest that selective laser trabeculoplasty could be a very important tool in the overall management of glaucoma patients at every stages, aiming to better control the visual field deterioration.</p><p><strong>Purpose: </strong>To evaluate selective laser trabeculoplasty (SLT) effectiveness in lowering intraocular pressure (IOP) and in visual field defect progression in eyes affected by primary open angle glaucoma (POAG) at long term follow up.</p><p><strong>Methods: </strong>A retrospective study were conducted with 67 eyes of 67 patients affected by POAG who underwent SLT between 2014 and 2021. Each patient was routinely observed in the Glaucoma Office of Università della Campania Luigi Vanvitelli and underwent a complete eye visit and visual field (VF) test with 30-2 SITA standard automated perimetry (SAP) every 6 months. When both eyes in same patient were treated, only the eye with lower mean deviation (MD) of SAP was included. Patients were observed at 6, 12, 18, 24, 30, 36, 42, 48, 54 months.</p><p><strong>Results: </strong>A mean significant (P<0.01) lower IOP was detected at 6 months (12.92±2.7 mm Hg) ad at 54 months (13.08±2.42 mm Hg) compared to baseline (17.91±4 mm Hg). Mean MD values showed significant (P<0.01) reduction both at 6 month follow up (-0.07±0.21 dB) and at 54 month follow up (-0.3±0.34 dB) demonstrating satisfactory clinical deceleration of the progression of the disease.Mean IOP medical lowering therapy was 1.34±0.9 drugs, showing a significant (P<0.01) decrease 6 months after SLT (0.87±0.85), that remained stable (P= at 54 month follow up (0.9±0.76).</p><p><strong>Conclusions: </strong>The results observed confirm not only the high level of effectiveness of SLT in lowering IOP and reducing the need for topical medications, but also its role in decelerating visual field deterioration in eyes affected by POAG.</p>","PeriodicalId":15938,"journal":{"name":"Journal of Glaucoma","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143189492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}