Journal of Helminthology最新文献_第2页

Patterns of helminth parasite infections in cyclic common vole (Microtus arvalis) populations. 环斑田鼠（Microtus arvalis）种群中寄生虫感染模式。

IF 1.6 3区生物学

Journal of Helminthology Pub Date : 2026-04-08 DOI: 10.1017/S0022149X26101412

E Trapote, S Herrero-Cófreces, H Henttonen, J J Luque-Larena, F Mougeot

{"title":"Patterns of helminth parasite infections in cyclic common vole (Microtus arvalis) populations.","authors":"E Trapote, S Herrero-Cófreces, H Henttonen, J J Luque-Larena, F Mougeot","doi":"10.1017/S0022149X26101412","DOIUrl":"https://doi.org/10.1017/S0022149X26101412","url":null,"abstract":"Research on parasite-induced regulation has identified the conditions under which parasites can destabilise host population dynamics: high levels of aggregation, delayed density-dependence, and moderate negative effects on fitness (reproduction, survival). Gastrointestinal helminths with direct life cycles and a single definitive host provide ideal systems to test these predictions. In this study, we first determined which helminths infect common voles (Microtus arvalis) in NW Spain, where populations are cyclic. We showed that the helminth community is dominated by Syphacia sp., a gut-restricted, directly transmitted nematode.We then examined how the prevalence and abundance of Syphacia sp. varied with host sex, season, and population cycle phase (increase, peak, or crash), and tested if vole condition (relative body mass and organ hypertrophy) and female fecundity (litter size) correlated with the prevalence of Syphacia sp. Infections were highly aggregated in Syphacia sp. and parasite abundance peaked during the crash phase of the vole cycle. We found that vole condition did not vary with the prevalence of Syphacia sp., but vole litter size showed a season-dependent association, with infected females producing smaller litters in spring and summer.These findings suggest that even low-pathogenic, directly transmitted parasites could exert reproductive effects, potentially shaping host population dynamics in combination with ecological and demographic factors. Experimental approaches are required to clarify causality and potential regulatory feedback.","PeriodicalId":15928,"journal":{"name":"Journal of Helminthology","volume":"100 ","pages":"e34"},"PeriodicalIF":1.6,"publicationDate":"2026-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147632723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In vivo and in vitro anthelmintic activity of quebracho-chestnut tannin extract against Haemonchus contortus in lambs. 板栗鞣质提取物对羔羊弯曲血蜱的体内、体外驱虫活性研究。

IF 1.6 3区生物学

Journal of Helminthology Pub Date : 2026-04-08 DOI: 10.1017/S0022149X26101357

M F Bruttomesso, G E Morici, M R Arias, C J Garro, S I Lobayan, M P Palladino, F A Illanes, J H Schapiro

{"title":"In vivo and in vitro anthelmintic activity of quebracho-chestnut tannin extract against Haemonchus contortus in lambs.","authors":"M F Bruttomesso, G E Morici, M R Arias, C J Garro, S I Lobayan, M P Palladino, F A Illanes, J H Schapiro","doi":"10.1017/S0022149X26101357","DOIUrl":"https://doi.org/10.1017/S0022149X26101357","url":null,"abstract":"Haemonchus contortus is considered the most pathogenic gastrointestinal nematode of sheep and, due to the increasing resistance to synthetic anthelmintics, it poses a serious challenge to small ruminant production systems. The aim of this work was to evaluate the in vivo and in vitro anthelmintic activity of quebracho-chestnut tannin extract against Haemonchus contortus in lambs. The in vitro assays (egg hatching inhibition and larval migration inhibition) were performed to determine the effective concentrations required to inhibit 50% of egg hatching and larval migration (EC50), which were 3.8 and 1.4 mg/mL, respectively. For the in vivo trial, 18 lambs used were divided into three groups: Group 1 (control), Group 2 (a tannin dose equivalent to 0.3% of dry matter intake), and Group 3 (a tannin dose equivalent to 3% of dry matter intake). No significant differences (p > 0.05) were observed among treatments in faecal egg counts, larval counts from coprocultures, or adult H. contortus recovery. The tannin extract was effective in inhibiting egg hatching and larval migration in vitro at low concentrations. However, when administered in vivo at 0.3% and 3% of dry matter intake, it failed to show any effect on faecal egg counts, larval counts in coproculture, or adult worm burden. Adult worms, eggs, and infective larvae were further examined using scanning electron microscopy. The observations revealed significant cuticular alterations in adult worms, which could potentially interfere with normal feeding and reproductive processes. Additionally, eggs and infective larvae exhibited shell rupture and cuticle damage.","PeriodicalId":15928,"journal":{"name":"Journal of Helminthology","volume":"100 ","pages":"e35"},"PeriodicalIF":1.6,"publicationDate":"2026-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147633733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Epidemiology of gastrointestinal nematodes of free-ranging chickens (Gallus gallus domesticus) in Africa: A systematic review and meta-analysis. 非洲散养鸡（Gallus Gallus domesticus）胃肠道线虫的流行病学：系统综述和荟萃分析。

IF 1.6 3区生物学

Journal of Helminthology Pub Date : 2026-04-08 DOI: 10.1017/S0022149X26101400

I Walter, M P Malatji, I Nyagura, D Tembe, S Mukaratirwa

{"title":"Epidemiology of gastrointestinal nematodes of free-ranging chickens (Gallus gallus domesticus) in Africa: A systematic review and meta-analysis.","authors":"I Walter, M P Malatji, I Nyagura, D Tembe, S Mukaratirwa","doi":"10.1017/S0022149X26101400","DOIUrl":"https://doi.org/10.1017/S0022149X26101400","url":null,"abstract":"A systematic review and meta-analysis were conducted, and published estimates determined the pooled prevalence of gastrointestinal nematode parasites affecting free-ranging chickens in Africa. Peer-reviewed articles published between 1993 and 2024 were systematically searched and screened. Prevalence estimates based on 76 eligible articles showed that of the 74,789 free-ranging chickens screened, 13,625 were infected with gastrointestinal nematodes with an overall pooled prevalence of 15% (95% CI: 13-18%). Twenty-seven nematode species were recorded, of which Ascaridia galli and Heterakis gallinarum were the commonly reported species. Southern Africa recorded the highest pooled prevalence (22%; 95% CI: 13-33%), and western Africa had the lowest (5%; 95% CI: 0-2%) despite recording the highest nematode species diversity. Tetrameridae had the highest family-level pooled prevalence of 46% (95% CI: 28-64%), and Spiruridae had the lowest 1% (95% CI: 0-3%). Most studies were conducted between the period 2014 and 2024; however, the highest pooled prevalence was observed between 1993 and 2002 (17%; 95% CI: 11-24%). The necropsy technique recorded the highest pooled prevalence (17%; 95% CI: 14-20%) compared to coproscopy (10%; 95% CI: 7-14%). The quality effects model revealed a high heterogeneity and publication bias among studies due to the diagnostic method used (P <0.05). This systematic review provided insightful information on the occurrence and potential burden of gastrointestinal nematode species of free-ranging chickens in Africa, highlighting the need for enhanced biosecurity and further research to safeguard their health, production, and food security of rural economies.","PeriodicalId":15928,"journal":{"name":"Journal of Helminthology","volume":"100 ","pages":"e36"},"PeriodicalIF":1.6,"publicationDate":"2026-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147632771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

New species of Neodiplostomum (Trematoda: Diplostomidae) from Argentine Patagonian birds: morphological and molecular characterisation. 阿根廷巴塔哥尼亚鸟类新双孔虫新种（吸虫目：双孔虫科）：形态和分子特征。

IF 1.6 3区生物学

Journal of Helminthology Pub Date : 2026-04-07 DOI: 10.1017/S0022149X26101278

N E Martinez, V Flores, C Rauque, G Viozzi

{"title":"New species of Neodiplostomum (Trematoda: Diplostomidae) from Argentine Patagonian birds: morphological and molecular characterisation.","authors":"N E Martinez, V Flores, C Rauque, G Viozzi","doi":"10.1017/S0022149X26101278","DOIUrl":"https://doi.org/10.1017/S0022149X26101278","url":null,"abstract":"This study describes two new species of Neodiplostomum (Trematoda: Diplostomidae) and reports a new lineage parasitising birds in Northwestern Patagonia, Argentina, based on morphological and molecular evidence. Specimens were recovered from the intestines of Falco sparverius, Caracara plancus, Accipiter bicolor, and Strix rufipes between 2001 and 2025. Morphological analyses revealed that the new taxa, herein named Neodiplostomum sparverius n. sp., and Neodiplostomum caracara n. sp., and the unnamed species Neodiplostomum sp. 1 show differences mainly in body segment ratio, sucker size, and vitelline gland distribution. This work contributes 14 new sequences to this genus. Phylogenetic analyses of nuclear (28S rDNA) and mitochondrial (cox1) sequences placed N. sparverius n. sp. within a clade comprising Neodiplostomum banghami and Neodiplostomum americanum; Neodiplostomum sp. 1 clustered with Neodiplostomum microcotyle and Neodiplostomum vaucheri, among others, confirming the existence of two well-supported Neodiplostomum lineages: the first is restricted to avian hosts, whereas the second includes birds and mammals. These results provide the first record of species of the genus Neodiplostomum in Patagonia, and the first molecular sequences for species of this genus in Argentina, thus expanding the known diversity and distribution of the genus in South America. The integrative approach supports the need for taxonomic revision of the genus Neodiplostomum.","PeriodicalId":15928,"journal":{"name":"Journal of Helminthology","volume":"100 ","pages":"e33"},"PeriodicalIF":1.6,"publicationDate":"2026-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147627949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Complete mitochondrial genomes of four pharyngodonid nematodes reveal extensive gene order rearrangement. 四种咽线虫线粒体全基因组揭示了广泛的基因顺序重排。

IF 1.6 3区生物学

Journal of Helminthology Pub Date : 2026-04-06 DOI: 10.1017/S0022149X2610128X

B Tomé, D J Harris, F Jorge, A de Sousa, J Archer, A Muñoz-Merida, C Rato, A Perera, K P Mulder

{"title":"Complete mitochondrial genomes of four pharyngodonid nematodes reveal extensive gene order rearrangement.","authors":"B Tomé, D J Harris, F Jorge, A de Sousa, J Archer, A Muñoz-Merida, C Rato, A Perera, K P Mulder","doi":"10.1017/S0022149X2610128X","DOIUrl":"https://doi.org/10.1017/S0022149X2610128X","url":null,"abstract":"Nematodes are one of the most diverse groups of organisms, but much of their evolutionary history remains unresolved. Genetic tools have greatly advanced this field, especially in cases of cryptic diversity. Here, we reconstructed the mitogenomes of four parasitic nematodes, each from a different genus of the family Pharyngodonidae (Nematoda: Oxyuroidea): Spauligodon, Pharyngodon, Parapharyngodon, and Thelandros. For each species, whole genome sequencing was performed, using an Illumina HiSeq 2500 platform. Mitochondrial genomes were reconstructed using both reference-based mapping and bait-based iterative assembly approaches. The resulting mitogenomes were 13,692 to 16,700 bp long, included 12 protein-coding genes, 22 tRNAs and the 12S and 16S rRNA regions and all lacked the ATP8 gene. All genes were on the same strand and in the same orientation, which is congruent with the composition and organization observed in other oxyurid nematodes. Also as observed in other nematode groups, the four mitogenomes exhibited major differences in gene order. It is still unknown what promotes such extensive gene order rearrangements within nematodes, even amongst related groups, but it is expected to influence the rates of evolution, especially for parasitic species, and help to explain their impressive diversity.","PeriodicalId":15928,"journal":{"name":"Journal of Helminthology","volume":"100 ","pages":"e32"},"PeriodicalIF":1.6,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147623170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Too hot to hold: climate change could reshape the map for a wild parasite. 太热了：气候变化可能会重塑一种野生寄生虫的地图。

IF 1.6 3区生物学

Journal of Helminthology Pub Date : 2026-03-30 DOI: 10.1017/S0022149X2610131X

F O Rossetti Neto, G Reis Brito, C B Galdino

{"title":"Too hot to hold: climate change could reshape the map for a wild parasite.","authors":"F O Rossetti Neto, G Reis Brito, C B Galdino","doi":"10.1017/S0022149X2610131X","DOIUrl":"https://doi.org/10.1017/S0022149X2610131X","url":null,"abstract":"Climate change is projected to alter the biology and distribution of many helminth species. We investigated the influence of climate on the current distribution of Parapharyngodon sceleratus, a monoxenic, generalist nematode parasite infecting 29 lizard species in South America, and evaluated its potential future range shifts under climate change. Using ecological niche modelling, we predicted the species' current and future range distributions. Precipitation-related variables were the primary determinants of the spatial distribution of the worm. Areas of medium to high environmental suitability are concentrated in regions with seasonal tropical warm climates, as well as temperate regions with dry summers and mild winters. Future projections indicate a progressive reduction of highly suitable areas and an expansion of areas with low suitability, particularly in northern and central South America, by 2100. However, the Atlantic Forest, the northeastern Brazilian coast, a site within the semiarid Caatinga, and open vegetation areas in Chile persist as refugia of high habitat suitability. Our findings suggest that rising temperatures and altered precipitation patterns may constrict the geographic range of this helminth. Contrary to predictions for other parasite taxa, our results highlight a negative impact of climate change on the distribution of a monoxenic helminth.","PeriodicalId":15928,"journal":{"name":"Journal of Helminthology","volume":"100 ","pages":"e30"},"PeriodicalIF":1.6,"publicationDate":"2026-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147573162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Parasites of two populations of Psalidodon bifasciatus (Characiformes): Enemy release suggesting introduction of hosts in Neotropical streams. 两种双歧诗齿鱼种群的寄生虫（特征）：天敌释放表明新热带溪流中引入了宿主。

IF 1.6 3区生物学

Journal of Helminthology Pub Date : 2026-03-30 DOI: 10.1017/S0022149X26101199

B S Miguel, L Franceschini, A C Zago, R L Delariva, J A Balbuena, I P Ramos

{"title":"Parasites of two populations of Psalidodon bifasciatus (Characiformes): Enemy release suggesting introduction of hosts in Neotropical streams.","authors":"B S Miguel, L Franceschini, A C Zago, R L Delariva, J A Balbuena, I P Ramos","doi":"10.1017/S0022149X26101199","DOIUrl":"https://doi.org/10.1017/S0022149X26101199","url":null,"abstract":"Psalidodon bifasciatus is a small characiform, originally described as endemic to the Iguaçu River basin. However, a recent study recorded a population of P. bifasciatus in the Piquiri River basin (upper Paraná), although data on its geographic distribution and parasitological aspects are still limited. The study characterized the parasitic fauna of P. bifasciatus in two streams, one from each basin, and compared them in terms of richness, diversity, and parasite community structure. Twenty-six females were collected in a stream in the lower Iguaçu River basin, and 25 females in a stream in the Piquiri River basin (upper Paraná) in September 2018. The parasite community structure of P. bifasciatus differed between areas, with a predominance of monopisthocotyls and greater richness of parasitic taxa for hosts in the lower Iguaçu River basin. In the Piquiri River basin (upper Paraná), the parasite community was characterized by a higher prevalence of larval nematodes and a lower richness of parasite taxa. The differences in the richness and structure of the parasite communities between the two areas support the hypothesis of the introduction of P. bifasciatus into the Piquiri River basin (upper Paraná). Therefore, we emphasize the need for further studies addressing the distribution pattern of P. bifasciatus, as well as additional parasitological studies to determine whether the parasitological taxa of P. bifasciatus are shared in other hydrological systems. This study contributes to the knowledge of the biological aspects of P. bifasciatus in both basins and improves our understanding of how host-parasite interactions can be informative in species introduction scenarios.","PeriodicalId":15928,"journal":{"name":"Journal of Helminthology","volume":"100 ","pages":"e29"},"PeriodicalIF":1.6,"publicationDate":"2026-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147574275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Parasite communities of lizards from the Carrasco, Chapada do Araripe, State of Ceará, Brazil: ecological and comparative approaches. 巴西塞埃尔<e:1>州卡拉斯科的蜥蜴寄生虫群落：生态学和比较方法。

IF 1.6 3区生物学

Journal of Helminthology Pub Date : 2026-03-30 DOI: 10.1017/S0022149X26101308

G M C Lacerda, J A D Araujo Filho, F B Pereira, S C Ribeiro

{"title":"Parasite communities of lizards from the Carrasco, Chapada do Araripe, State of Ceará, Brazil: ecological and comparative approaches.","authors":"G M C Lacerda, J A D Araujo Filho, F B Pereira, S C Ribeiro","doi":"10.1017/S0022149X26101308","DOIUrl":"https://doi.org/10.1017/S0022149X26101308","url":null,"abstract":"Lizards represent a diverse group, adapted to a wide variety of environments, and interact with a wide range of parasites. The composition of a parasitic community can be influenced by several factors, including the host, the environment, and the parasite itself. This study evaluated the composition of the helminth community in three species of lizards of the genera Ameiva, Ameivula, and Tropidurus, from a Carrasco habitat in Chapada do Araripe, Brazil. Carrasco is a little-explored environment in which the diversity of hosts and parasites is still poorly understood. The composition of the helminth community associated with lizard species was evaluated by comparing richness, evenness, dominance, and diversity among component communities, including host sex and size as influencing factors, using different statistical comparison tools. The community consisted of 12 taxa from eight genera of parasitic helminths, seven of which were Nematoda and one Cestoda. The factors analysed had different influences on the different parasitic communities of each host species. It was possible to determine the dissimilarity between host populations based on their parasitic communities, and it was observed that the host species itself represented the most important factor in the structuring of helminth communities. The information recorded here converges with other results obtained in different studies with lizards, but points to patterns in the helminth community that differ from those observed in other areas of the Caatinga. The results obtained reveal complex patterns of association between parasites and hosts, demonstrating the existence of ecological relationships that can be shaped by specific factors.","PeriodicalId":15928,"journal":{"name":"Journal of Helminthology","volume":"100 ","pages":"e31"},"PeriodicalIF":1.6,"publicationDate":"2026-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147574310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparative performance of Kato-Katz and spontaneous sedimentation methods for schistosomiasis mansoni diagnosis in endemic areas of Northeastern Brazil. 巴西东北部曼氏血吸虫病流行区加藤-卡茨法与自然沉降法诊断效果比较

IF 1.6 3区生物学

Journal of Helminthology Pub Date : 2026-03-26 DOI: 10.1017/S0022149X26101291

T L H Ferreira, V T C Campos, R E S Ramos, C Graeff-Teixeira, F A Brayner, A Rodrigues, R R Cambraia-Miranda, I G A Santos, J R S Silva, S S Dolabella

{"title":"Comparative performance of Kato-Katz and spontaneous sedimentation methods for schistosomiasis mansoni diagnosis in endemic areas of Northeastern Brazil.","authors":"T L H Ferreira, V T C Campos, R E S Ramos, C Graeff-Teixeira, F A Brayner, A Rodrigues, R R Cambraia-Miranda, I G A Santos, J R S Silva, S S Dolabella","doi":"10.1017/S0022149X26101291","DOIUrl":"https://doi.org/10.1017/S0022149X26101291","url":null,"abstract":"Schistosomiasis mansoni, caused by the trematode Schistosoma mansoni, is a major public health issue in Northeastern Brazil. This study compares the diagnostic performance of Kato-Katz (KK) and spontaneous sedimentation (Lutz) techniques in detecting S. mansoni infections in three areas of Sergipe, Northeastern Brazil, each with varying degrees of schistosomiasis endemicity. We compared the performance of Kato-Katz (KK) and spontaneous sedimentation (SSM) in three localities of Sergipe and Alagoas with different endemicity levels. Stool samples were examined by both methods, and individuals were considered positive if at least one test was positive. KK showed higher sensitivity across all sites (88.5%-100%), while SSM performed better in moderately endemic areas (up to 61.5%). These complementary performance profiles suggest that using both methods in combination could yield a measurable increase in case detection - potentially improving prevalence estimates, guiding more accurate treatment interventions, and strengthening surveillance strategies in areas with heterogeneous transmission intensities.","PeriodicalId":15928,"journal":{"name":"Journal of Helminthology","volume":"100 ","pages":"e28"},"PeriodicalIF":1.6,"publicationDate":"2026-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147512754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Genetic diversity and evolutionary relationships of human-derived Ascaris spp. based on mitochondrial markers. 基于线粒体标记的人源蛔虫的遗传多样性和进化关系。

IF 1.6 3区生物学

Journal of Helminthology Pub Date : 2026-03-04 DOI: 10.1017/S0022149X26101242

M Thakur, A Mewara, P V M Lakshmi, S Guleria, S Khurana

{"title":"Genetic diversity and evolutionary relationships of human-derived Ascaris spp. based on mitochondrial markers.","authors":"M Thakur, A Mewara, P V M Lakshmi, S Guleria, S Khurana","doi":"10.1017/S0022149X26101242","DOIUrl":"10.1017/S0022149X26101242","url":null,"abstract":"Ascaris species are common soil-transmitted helminths infecting both humans and pigs. It is recognized as one of the Neglected Tropical Diseases and is currently targeted in global eradication initiatives. This study employed mitochondrial 'NADH dehydrogenase subunit 1 NAnad1) and Cytochrome Oxidase 1 (cox1) gene' sequences comprising newly generated and publicly available data to investigate the genetic diversity, evolutionary relationships, and potential zoonotic transmission between Ascaris lumbricoides and Ascaris suum. Phylogenetic analysis revealed distinct clustering, with Indian A. lumbricoides sequences showing close genetic affinity to Chinese and Brazilian sequences (Human and Pigs), indicating possible historical gene flow. This genetic relatedness indicates the presence of intra-species variability and supports earlier evidence of potential hybridization between A. lumbricoides and A. suum. Haplotype network analysis based on nad1 identified 27 haplotypes, including both shared and unique variants. Hap_1 and Hap_2 were widely distributed, while several Indian haplotypes were distinct, suggesting localized diversification or genetic divergence. Cox1-based analysis identified 25 haplotypes, with human sequences forming both global and region-specific clusters, and pig-derived A. suum sequences forming a separate clade. These results highlight substantial genetic diversity and underline the importance of molecular surveillance in understanding Ascaris transmission and zoonotic risk.","PeriodicalId":15928,"journal":{"name":"Journal of Helminthology","volume":"100 ","pages":"e27"},"PeriodicalIF":1.6,"publicationDate":"2026-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147348461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0