N. Paschalidis, N. Stamatopoulos, K. Karadamoglou, G. Kottaras, V. Paschalidis, E. Sarris, B. Andrews, R. Mcentire, S. Jaskulek, D. Mitchell, R. McNutt
{"title":"A time-of-flight system on a chip suitable for space instrumentation","authors":"N. Paschalidis, N. Stamatopoulos, K. Karadamoglou, G. Kottaras, V. Paschalidis, E. Sarris, B. Andrews, R. Mcentire, S. Jaskulek, D. Mitchell, R. McNutt","doi":"10.1109/NSSMIC.2001.1009667","DOIUrl":"https://doi.org/10.1109/NSSMIC.2001.1009667","url":null,"abstract":"A time-of-flight (TOF) system-on-a-chip (SoC) for precise time interval measurement at low power and high rate has been developed. A micro-channel plate (MCP) electron multiplier typically produces the start and stop of a radiation event to be processed. The TOF chip includes two Constant Fraction Discriminators (CFDs) and a Time to Digital Converter (TDC). The CFDs interface to start and stop anodes through two simple preamplifiers and perform the signal conditioning for time walk compensation. The TDC portion digitizes the time difference with reference to an external precise oscillator. A first version of the TOF chip developed in a 0.8 u CMOS process achieved /spl sim/350 ps total time resolution, including time walk and time jitter, with /spl sim/20 mW power consumption at a rate of /spl sim/100 K events/sec and /spl sim/30 mW @ 1Mevents/sec. This chip is part of the HENA instrument of the NASA/IMAGE mission launched in March 2000 and is baselined for many other missions including the Energetic Particle Sensor (EPS) of Messenger etc.","PeriodicalId":159123,"journal":{"name":"2001 IEEE Nuclear Science Symposium Conference Record (Cat. No.01CH37310)","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132863507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Kapusta, P. Crespo, M. Moszynski, W. Enghardt, M. Szawłowski, B. Zhou, D. Wolski
{"title":"Evaluation of LAAPD arrays for high-resolution scintillator matrices readout","authors":"M. Kapusta, P. Crespo, M. Moszynski, W. Enghardt, M. Szawłowski, B. Zhou, D. Wolski","doi":"10.1109/NSSMIC.2001.1009639","DOIUrl":"https://doi.org/10.1109/NSSMIC.2001.1009639","url":null,"abstract":"In this paper, we evaluate the performance of recently released avalanche photodiode arrays from Advanced Photonix. Inc. (API) for scintillator matrices readout. The Large Area Avalanche Photodiode (LAAPD) quadrant device is a monolithic 2 /spl times/ 2 pixels structure with an active area of 5.3 mm/sup 2/ per pixel. The device allows stable operation with high gains up to 200, and detection efficiency of 73 /spl plusmn/ 10% for 420 nm photons. It is furthermore characterized by a high linear fill factor of 90% and low noise equal to 16 electrons ENC measured at room temperature. We have measured pixel-to-pixel gain nonuniformity smaller than 1.5% and inter-pixel crosstalk of 1.7% in the pulse mode operation with the device gain of 50. The energy resolution of 12.3 /spl plusmn/ 0.5% was achieved for the 511 keV photopeak from a /sup 22/Na source placed on top of a 2 /spl times/ 2 /spl times/ 10 mm LSO crystal coupled to one pixel of quadrant LAAPD. An array of LSO crystals was later coupled to the device allowing individual crystal identification. Coincidence timing resolution of 1.9 /spl plusmn/ 0.1 ns FWHM has been obtained for quadrant pixel with LSO scintillator for the 511 keV peak from /sup 22/Na source. Finally, we compared the characteristics and readout performance of LAAPD array with published results of some commercially available APD arrays.","PeriodicalId":159123,"journal":{"name":"2001 IEEE Nuclear Science Symposium Conference Record (Cat. No.01CH37310)","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133421757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Anghinolfi, W. Białas, N. Busek, A. Ciocio, D. Cosgrove, V. Fadeyev, C. Flacco, M. Gilchriese, A. Grillo, C. Haber, J. Kapłon, C. Lacasta, W. Murray, H. Niggli, T. Pritchard, F. Rosenbaum, H. Spieler, T. Stezelberger, C. Vu, M. Wilder, H. Yaver, F. Zetti
{"title":"ASIC wafer test system for the ATLAS Semiconductor Tracker front-end chip","authors":"F. Anghinolfi, W. Białas, N. Busek, A. Ciocio, D. Cosgrove, V. Fadeyev, C. Flacco, M. Gilchriese, A. Grillo, C. Haber, J. Kapłon, C. Lacasta, W. Murray, H. Niggli, T. Pritchard, F. Rosenbaum, H. Spieler, T. Stezelberger, C. Vu, M. Wilder, H. Yaver, F. Zetti","doi":"10.1109/NSSMIC.2001.1009645","DOIUrl":"https://doi.org/10.1109/NSSMIC.2001.1009645","url":null,"abstract":"An ASIC wafer test system has been developed to provide comprehensive production screening of the ATLAS Semiconductor Tracker front-end chip (ABCD3T). The ABCD3T features a 128-channel analog front-end, a digital pipeline, and communication circuitry, clocked at 40 MHz, which is the bunch crossing frequency at the LHC (Large Hadron Collider). The tester measures values and tolerance ranges of all critical IC parameters, including DC parameters, electronic noise, time resolution, clock levels and clock timing. The tester is controlled by an FPGA (ORCA3T) programmed to issue the input commands to the IC and to interpret the output data. This allows the high-speed wafer-level IC testing necessary to meet the production schedule. To characterize signal amplitudes and phase margins, the tester utilizes pin-driver, delay, and DAC chips, which control the amplitudes and delays of signals sent to the IC under test. Output signals from the IC under test go through window comparator chips to measure their levels. A probe card has been designed specifically to reduce pick-up noise that can affect the measurements. The system can operate at frequencies up to 100 MHz to study the speed limits of the digital circuitry before and after radiation damage. Testing requirements and design solutions are presented.","PeriodicalId":159123,"journal":{"name":"2001 IEEE Nuclear Science Symposium Conference Record (Cat. No.01CH37310)","volume":"73 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132274340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B. Evans, J.B. Martin, L. Burggraf, T. Hangartner, M. Roggemann
{"title":"Demonstration of single-sided Compton scatter tomography in fan beams with an HPGe array","authors":"B. Evans, J.B. Martin, L. Burggraf, T. Hangartner, M. Roggemann","doi":"10.1109/NSSMIC.2001.1009709","DOIUrl":"https://doi.org/10.1109/NSSMIC.2001.1009709","url":null,"abstract":"An instrument is demonstrated whereby radiographic images of a sample's electron density are compiled from the information encoded in the energy spectra of gamma rays backscattered from one side of the sample. Nondestructive inspection of aluminum airframes is the application of interest, so it is assumed that access is restricted to only one surface of the object under inspection. Use of energy coding allows imaging in a fan beam rather than independent interrogation of individual volume elements. The Multiplexed Compton Scatter Tomograph (MCST) instrument consists of an array of planar high-purity germanium detectors, a set of fan beam collimators, and a Cd/sup 109/ radionuclide source. Instrument signals are converted to electron density images using a penalized weighted least squares image reconstruction algorithm coupled with a deterministic system model that includes effects of finite source and detector size, detector resolution and efficiency, attenuation, and Doppler broadening. The Doppler broadening, resulting from the momentum distribution of bound electrons, is significant at the energies used here. The proof-of-principle instrument is demonstrated on some aluminum samples. In an 8-mm thick sample with a 4 mm void in its center, contrast recovery of 90% is achieved. In a 10-mm thick sample with a 3 rum void at the back, about 85% of the contrast is recovered.","PeriodicalId":159123,"journal":{"name":"2001 IEEE Nuclear Science Symposium Conference Record (Cat. No.01CH37310)","volume":"1967 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128812068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Fazzi, G. Betta, G. Pignatel, M. Boscardin, P. Gregori, N. Zorzi
{"title":"PIN diode and integrated JFET on high resistivity silicon: a new test structure","authors":"A. Fazzi, G. Betta, G. Pignatel, M. Boscardin, P. Gregori, N. Zorzi","doi":"10.1109/NSSMIC.2001.1008445","DOIUrl":"https://doi.org/10.1109/NSSMIC.2001.1008445","url":null,"abstract":"A new test structure intended as a pixel for segmented X- and /spl gamma/-ray detectors has been designed fabricated and tested. The structure consists of a PIN diode of 0.8 mm/sup 2/ area and of an n-channel JFET integrated on the same high resistivity (6 k/spl Omega/ cm) silicon chip. The electrical parameters-leakage current, the transconductance and the capacitance have good expected values. Instead, noise in excess is present in the transistor. Operated at room temperature as an X-ray detector with the integrated frontend transistor in the charge sensitive configuration, the new test structure shows an equivalent noise charge of about 60 electrons rms at the optimum shaping time of 3-6 /spl mu/s.","PeriodicalId":159123,"journal":{"name":"2001 IEEE Nuclear Science Symposium Conference Record (Cat. No.01CH37310)","volume":"540 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131843689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"New ways for purifying lead iodide appropriate as spectrometric grade material","authors":"E. Saucedo, L. Fornaro, L. Mussio, A. Gancharov","doi":"10.1109/NSSMIC.2001.1009291","DOIUrl":"https://doi.org/10.1109/NSSMIC.2001.1009291","url":null,"abstract":"In order to overcome some unsolved problems of lead iodide purification such as lack of stoichiometry, decomposition and polytype admixture, several purification methods were compared. Lead iodide Alfa Aesar and synthesized from lead nitrate and potassium iodide was purified by zone refining, zone refining followed by sublimation, repeated sublimation and repeated evaporation, at different conditions. Zone refining was performed at 420/spl deg/C, 3 cm/hr, 100 passes, repeated sublimation at 390/spl deg/C and vacuum (10/sup -5/ mmHg) or Ar atmosphere (500 to 580 mmHg) and repeated evaporation at 10/sup -5/ mmHg or in Ar atmosphere (150 to 600 mmHg) and temperature from 450/spl deg/C to 600/spl deg/C. Purification methods were evaluated by studying parameters of the purified material like decomposition, stoichiometry, purity and polytype composition and also taking into account purification yield and rate. Stoichiometry was determined by wet procedures, purity by Inductively Coupled Plasma (ICP) and polytypes by powder X-ray diffraction. Evaporation of lead iodide at the highest temperature and moderate Ar pressure (600/spl deg/C and 500-600 mmHg) proved to be the best way to avoid material decomposition. Sublimation and evaporation give the best stoichiometry (PbI/sub 1.90/) especially when compared with zone refining (PbI/sub 1.40/). Whatever the purification method, material has an appreciable polytype content. Purity showed similar results for 100 zone refining passes than for 3 evaporations. Furthermore, evaporation exhibits maximum yield and rate (16%/day). Therefore, the work performed points out evaporation in Ar atmosphere as the quickest and more efficient purification method for producing spectrometric grade lead iodide, avoiding material decomposition and achieving high purity, but maintaining the best stoichiometry.","PeriodicalId":159123,"journal":{"name":"2001 IEEE Nuclear Science Symposium Conference Record (Cat. No.01CH37310)","volume":"163 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127423786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Hadi, A. Giouvanoudi, R. Morton, P. Horton, N. Spyrou
{"title":"Variations in gastric emptying times of three stomach regions for simple and complex meals using scintigraphy","authors":"N. Hadi, A. Giouvanoudi, R. Morton, P. Horton, N. Spyrou","doi":"10.1109/NSSMIC.2001.1008587","DOIUrl":"https://doi.org/10.1109/NSSMIC.2001.1008587","url":null,"abstract":"Electrical impedance epigastrography has been used to study gastric emptying and contractions in subjects when fed simple and complex meals. In order to validate findings, simultaneous measurements have been carried out using the more conventional scintigraphic technique together with epigastrography. On analysis of data and in estimating emptying times with scintigraphy, variations have been found in the half-emptying values depending on the region of the stomach selected. In this work, the results of the scintigraphic data analysis for emptying times of the fundus, body and antrum as well as the whole stomach are presented. When a meal enters the stomach, mixing waves begin. These waves macerate the meal with gentle, rippling, peristaltic movements, mixing it with secretions of the gastric glands. Few mixing waves are observed in the fundus, which primarily functions as a storage compartment. More vigorous mixing waves begin at the body part and persist for a few minutes before intensifying as they reach the antrum. Scintigraphic measurements of gastric emptying using the tri-regional pattern can be sensitive in quantifying emptying of simple and complex liquids and the method has the ability to measure the emptying rates of the different parts of the stomach for these meals. Observed relationships between scintigraphic measurements of the various parts of the stomach and gastric emptying indicate that in all types of meals, the body region represents well the overall emptying time of the whole stomach, whereas in the antral region, the emptying time is longer for the simple beverages and relatively shorter for the complex ones.","PeriodicalId":159123,"journal":{"name":"2001 IEEE Nuclear Science Symposium Conference Record (Cat. No.01CH37310)","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133720581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assessment of image quality with a fast fully 3D reconstruction algorithm","authors":"M. Daube-Witherspoon, S. Matej, J. Karp","doi":"10.1109/NSSMIC.2001.1009269","DOIUrl":"https://doi.org/10.1109/NSSMIC.2001.1009269","url":null,"abstract":"True three-dimensional (3D) reconstructions from fully 3D positron emission tomography (PET) data yield high-quality images but at a high computational cost. Image representation using three-dimensional spherically-symmetric basis functions on a body-centered cubic (BCC) grid, as opposed to a simple cubic (SC) grid, can reduce the computational demands of a 3D approach without compromising image quality by reducing the number of image elements to be reconstructed. The goal of this study was to determine if the image quality improvements predicted for the 3D row action maximum likelihood algorithm (RAMLA) over 2.5D RAMLA after Fourier rebinning (FORE) would be seen with clinical PET data. Torso phantom, whole-body patient, and brain patient studies were used in this analysis. Data were corrected for detector efficiency, scatter, and randoms prior to reconstruction. Attenuation effects were either incorporated into the system model or pre-corrected prior to reconstruction. Higher contrast at comparable noise levels (or lower noise for comparable contrast) are seen with 3D RAMLA (SC or BCC grid) for both phantom and patient data. The brain patient data show improved axial resolution with 3D RAMLA, where the degradation in resolution with FORE is eliminated. Application of a fully 3D reconstruction algorithm is possible in clinically reasonable times.","PeriodicalId":159123,"journal":{"name":"2001 IEEE Nuclear Science Symposium Conference Record (Cat. No.01CH37310)","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115728737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Input recovery from noisy output measurements: a Monte Carlo method","authors":"Koon-Pong Wong, S. Meikle, D. Feng, M. Fulham","doi":"10.1109/NSSMIC.2001.1008601","DOIUrl":"https://doi.org/10.1109/NSSMIC.2001.1008601","url":null,"abstract":"Accurate determination of the input function is essential for absolute quantification of physiological parameters in PET and SPECT imaging but it requires an invasive and tedious procedure of blood sampling that is impractical in clinical studies. We previously proposed a technique that simultaneously estimates kinetic parameters and the input function from the tissue impulse response functions and which requires only two blood samples. A nonlinear least squares method was used to estimate all the parameters in the impulse response functions and the input function but it fails occasionally due to high noise levels in the data causing an ill-conditioned cost function. This study investigates the feasibility of applying a Monte Carlo method called simulated annealing to estimate kinetic parameters in the impulse response functions and the input function. Time-activity curves of teboroxime, which is very sensitive to changes in the input function, were simulated based on published data obtained from a canine model. The equations describing the tracer kinetics in different regions were minimised simultaneously by simulated annealing and nonlinear least squares. We found that the physiological parameters obtained with simulated annealing are more accurate and the estimated input function more closely resembled the simulated curve. We conclude that simulated annealing reduces bias in the estimation of physiological parameters and determination of the input function.","PeriodicalId":159123,"journal":{"name":"2001 IEEE Nuclear Science Symposium Conference Record (Cat. No.01CH37310)","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115882014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"3D geometric normalization for the high resolution quad-HIDAC PET scanner","authors":"Hua-Xia Zhao, A. Reader","doi":"10.1109/NSSMIC.2001.1009752","DOIUrl":"https://doi.org/10.1109/NSSMIC.2001.1009752","url":null,"abstract":"The high sensitivity, high resolution, quad-HIDAC PET scanner consists of 4 main detector banks which each contain either 4 or 8 detector modules, with 2 converter planes in each module. Coincidences are collected between opposite detector banks only, and not all lines of response (LORs) which are measurable by the system pass through the same number of detector planes, due to the finite axial extent of the stack of detector planes. Therefore, in order to utilize all the acquired data, it is necessary to account for this sensitivity variation for the system LORs. Existing reconstruction methods for the quad-HIDAC have not accounted for this, resulting in typically /spl sim/14% of the data being rejected in the 16-module quad-HIDAC and /spl sim/24% being rejected in the 32-module quad-HIDAC. This work presents the sensitivity calculation which is necessary to compensate for under-sampled LORs, by evaluating the solid angle as a function of position throughout the field of view - which gives rise to a correction scheme for incorporation into iterative list-mode reconstruction algorithms. This allows all the acquired data to be used in the image reconstruction process.","PeriodicalId":159123,"journal":{"name":"2001 IEEE Nuclear Science Symposium Conference Record (Cat. No.01CH37310)","volume":"105 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114354424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}