Journal of Heart and Lung Transplantation最新文献

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Transplanting beyond anatomy: When congenital heart disease challenges persist despite a new heart 超越解剖的移植:当先天性心脏病的挑战持续存在,尽管有一个新的心脏。
IF 6 1区 医学
Journal of Heart and Lung Transplantation Pub Date : 2025-07-30 DOI: 10.1016/j.healun.2025.07.025
Nicola Pradegan MD, Gino Gerosa MD
{"title":"Transplanting beyond anatomy: When congenital heart disease challenges persist despite a new heart","authors":"Nicola Pradegan MD, Gino Gerosa MD","doi":"10.1016/j.healun.2025.07.025","DOIUrl":"10.1016/j.healun.2025.07.025","url":null,"abstract":"","PeriodicalId":15900,"journal":{"name":"Journal of Heart and Lung Transplantation","volume":"44 11","pages":"Page 1830"},"PeriodicalIF":6.0,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144763552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cold chain study of donor lungs reminds us to consider the re-warming occurring during the implant procedure 供体肺的冷链研究提醒我们考虑在植入过程中发生的再升温。
IF 6 1区 医学
Journal of Heart and Lung Transplantation Pub Date : 2025-07-28 DOI: 10.1016/j.healun.2025.07.021
J.S. Parmar BM, PhD, FRCP, FFICM , P. Catarino MD, FRCS
{"title":"Cold chain study of donor lungs reminds us to consider the re-warming occurring during the implant procedure","authors":"J.S. Parmar BM, PhD, FRCP, FFICM , P. Catarino MD, FRCS","doi":"10.1016/j.healun.2025.07.021","DOIUrl":"10.1016/j.healun.2025.07.021","url":null,"abstract":"","PeriodicalId":15900,"journal":{"name":"Journal of Heart and Lung Transplantation","volume":"44 11","pages":"Pages 1747-1748"},"PeriodicalIF":6.0,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144747957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Why Ukraine is important to ISHLT – The Kiev Heart Institute brings hope to the world 为什么乌克兰对ISHLT很重要-基辅心脏研究所为世界带来希望。
IF 6 1区 医学
Journal of Heart and Lung Transplantation Pub Date : 2025-07-28 DOI: 10.1016/j.healun.2025.07.022
G. Dellgren MD, PhD
{"title":"Why Ukraine is important to ISHLT – The Kiev Heart Institute brings hope to the world","authors":"G. Dellgren MD, PhD","doi":"10.1016/j.healun.2025.07.022","DOIUrl":"10.1016/j.healun.2025.07.022","url":null,"abstract":"","PeriodicalId":15900,"journal":{"name":"Journal of Heart and Lung Transplantation","volume":"44 11","pages":"Pages 1735-1736"},"PeriodicalIF":6.0,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144747884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Information for Readers 读者资讯
IF 6.4 1区 医学
Journal of Heart and Lung Transplantation Pub Date : 2025-07-25 DOI: 10.1016/S1053-2498(25)02097-2
{"title":"Information for Readers","authors":"","doi":"10.1016/S1053-2498(25)02097-2","DOIUrl":"10.1016/S1053-2498(25)02097-2","url":null,"abstract":"","PeriodicalId":15900,"journal":{"name":"Journal of Heart and Lung Transplantation","volume":"44 8","pages":"Page A2"},"PeriodicalIF":6.4,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144702587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Video kinematics of an unloaded, ex-vivo beating heart can predict future loaded heart function 视频运动学的卸载,离体跳动的心脏可以预测未来负荷心脏功能。
IF 6 1区 医学
Journal of Heart and Lung Transplantation Pub Date : 2025-07-25 DOI: 10.1016/j.healun.2025.07.023
Brian C. Ayers , George Olverson , Chijioke Chukwudi , Manuela Lopera Higuita , Emmanuella Ajenu , Maya Bolger-Chen , Joseph Catricala , Allison Pitti , Yaghoubian Koushiar Moshe , Jagdip Kang , Aaron D. Aguirre , Thoralf M. Sundt , Eriberto Michel , Asishana Osho , Shannon N. Tessier , S. Alireza Rabi , David D’Alessandro
{"title":"Video kinematics of an unloaded, ex-vivo beating heart can predict future loaded heart function","authors":"Brian C. Ayers ,&nbsp;George Olverson ,&nbsp;Chijioke Chukwudi ,&nbsp;Manuela Lopera Higuita ,&nbsp;Emmanuella Ajenu ,&nbsp;Maya Bolger-Chen ,&nbsp;Joseph Catricala ,&nbsp;Allison Pitti ,&nbsp;Yaghoubian Koushiar Moshe ,&nbsp;Jagdip Kang ,&nbsp;Aaron D. Aguirre ,&nbsp;Thoralf M. Sundt ,&nbsp;Eriberto Michel ,&nbsp;Asishana Osho ,&nbsp;Shannon N. Tessier ,&nbsp;S. Alireza Rabi ,&nbsp;David D’Alessandro","doi":"10.1016/j.healun.2025.07.023","DOIUrl":"10.1016/j.healun.2025.07.023","url":null,"abstract":"<div><div>There is not a reliable biomarker for identifying which hearts are at highest risk for primary graft dysfunction. We hypothesize that ex-vivo video kinematics (EVVK) of unloaded beating hearts can help predict post-implant heart performance. Porcine hearts procured following a DCD protocol were re-animated in unloaded ex situ heart perfusion (ESHP) before transitioning to a loaded configuration. Five second videos were recorded using a consumer cell phone. Machine learning EVVK software was developed to autonomously quantify heart function. Of 22 porcine hearts, 6 (27%) did not tolerate loading. EVVK demonstrated prognostic capability to differentiate the future loaded performance in terms of both compliance (p=0.004) and contractility (p=0.003). We also demonstrate proof-of-concept in using EVVK on human hearts (n=4) to provide a quantitative functional assessment of the allograft during transportation from the donor to recipient center. Overall, non-invasive EVVK may be able to aid clinicians in quantitative heart evaluation.</div></div>","PeriodicalId":15900,"journal":{"name":"Journal of Heart and Lung Transplantation","volume":"44 11","pages":"Pages 1823-1826"},"PeriodicalIF":6.0,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144719945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Response to Urschel et al 回应Urschel等人
IF 6.4 1区 医学
Journal of Heart and Lung Transplantation Pub Date : 2025-07-25 DOI: 10.1016/j.healun.2025.03.028
Daniel J. Hurst PhD, ThM, MDiv, MSc , Anthony Merlocco MD, MSt, FSCMR
{"title":"Response to Urschel et al","authors":"Daniel J. Hurst PhD, ThM, MDiv, MSc ,&nbsp;Anthony Merlocco MD, MSt, FSCMR","doi":"10.1016/j.healun.2025.03.028","DOIUrl":"10.1016/j.healun.2025.03.028","url":null,"abstract":"","PeriodicalId":15900,"journal":{"name":"Journal of Heart and Lung Transplantation","volume":"44 8","pages":"Page 1354"},"PeriodicalIF":6.4,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144702503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Authors’ Perspective on 'Summary of the International Society for Heart and Lung Transplantation Consensus Conference on Emerging Understanding of Antibodies and Antibody-mediated Rejection in Heart Transplantation' 作者对“国际心肺移植学会关于心脏移植中抗体和抗体介导的排斥反应的新认识共识会议总结”的看法
IF 6.4 1区 医学
Journal of Heart and Lung Transplantation Pub Date : 2025-07-25 DOI: 10.1016/j.healun.2025.05.010
Jon Kobashigawa MD , Andreas Zuckermann MD , Adriana Zeevi PhD , Markus J. Barten MD, PhD , Patricia P. Chang MD, MHS , Monica Colvin MD, MS , Guillaume Coutance MD, PhD , Anne Dipchand MD , Stephan Ensminger MD, DPhil , Marta Farrero MD , Marlena Habal MD , Anne Halpin PhD , Annette M. Jackson PhD , Yosef Manla MD , Kavitha Muthiah MBBS, PhD , Luciano Potena MD, PhD , Elaine F. Reed PhD , Kelly Schlendorf MD, MHS , Palak Shah MD, MS , Anat Tambur DMD, PhD , Jignesh Patel MD, PhD
{"title":"The Authors’ Perspective on 'Summary of the International Society for Heart and Lung Transplantation Consensus Conference on Emerging Understanding of Antibodies and Antibody-mediated Rejection in Heart Transplantation'","authors":"Jon Kobashigawa MD ,&nbsp;Andreas Zuckermann MD ,&nbsp;Adriana Zeevi PhD ,&nbsp;Markus J. Barten MD, PhD ,&nbsp;Patricia P. Chang MD, MHS ,&nbsp;Monica Colvin MD, MS ,&nbsp;Guillaume Coutance MD, PhD ,&nbsp;Anne Dipchand MD ,&nbsp;Stephan Ensminger MD, DPhil ,&nbsp;Marta Farrero MD ,&nbsp;Marlena Habal MD ,&nbsp;Anne Halpin PhD ,&nbsp;Annette M. Jackson PhD ,&nbsp;Yosef Manla MD ,&nbsp;Kavitha Muthiah MBBS, PhD ,&nbsp;Luciano Potena MD, PhD ,&nbsp;Elaine F. Reed PhD ,&nbsp;Kelly Schlendorf MD, MHS ,&nbsp;Palak Shah MD, MS ,&nbsp;Anat Tambur DMD, PhD ,&nbsp;Jignesh Patel MD, PhD","doi":"10.1016/j.healun.2025.05.010","DOIUrl":"10.1016/j.healun.2025.05.010","url":null,"abstract":"","PeriodicalId":15900,"journal":{"name":"Journal of Heart and Lung Transplantation","volume":"44 8","pages":"Pages 1195-1198"},"PeriodicalIF":6.4,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144702691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comments and opinions regarding “Volume calibration with cardiac MRI versus hypertonic saline for right ventricular pressure-volume loops with exercise: Impact on ventricular function and ventricular-vascular coupling” by Raza et al. 关于Raza等人的“心脏MRI容积校准与高渗盐水对运动右心室压力-容积循环的影响:对心室功能和心室-血管耦合的影响”的评论和观点。
IF 6.4 1区 医学
Journal of Heart and Lung Transplantation Pub Date : 2025-07-25 DOI: 10.1016/j.healun.2025.03.024
Nils Kremer , Zvonimir Rako , Khodr Tello
{"title":"Comments and opinions regarding “Volume calibration with cardiac MRI versus hypertonic saline for right ventricular pressure-volume loops with exercise: Impact on ventricular function and ventricular-vascular coupling” by Raza et al.","authors":"Nils Kremer ,&nbsp;Zvonimir Rako ,&nbsp;Khodr Tello","doi":"10.1016/j.healun.2025.03.024","DOIUrl":"10.1016/j.healun.2025.03.024","url":null,"abstract":"","PeriodicalId":15900,"journal":{"name":"Journal of Heart and Lung Transplantation","volume":"44 8","pages":"Pages 1350-1351"},"PeriodicalIF":6.4,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144702501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Response to comments and opinions by Kremer et al regarding our original manuscript “Volume calibration with cardiac MRI vs hypertonic saline for right ventricular pressure-volume loops with exercise: Impact on ventricular function and ventricular-vascular coupling” 对Kremer等人对我们的原稿“心脏MRI容积校准与高渗盐水对运动右室压力-容积环路的影响:对心室功能和心室-血管耦合的影响”的评论和意见的回应
IF 6.4 1区 医学
Journal of Heart and Lung Transplantation Pub Date : 2025-07-25 DOI: 10.1016/j.healun.2025.04.007
Farhan Raza MD , Chris G. Lechuga PhD , Naomi C. Chesler PhD
{"title":"Response to comments and opinions by Kremer et al regarding our original manuscript “Volume calibration with cardiac MRI vs hypertonic saline for right ventricular pressure-volume loops with exercise: Impact on ventricular function and ventricular-vascular coupling”","authors":"Farhan Raza MD ,&nbsp;Chris G. Lechuga PhD ,&nbsp;Naomi C. Chesler PhD","doi":"10.1016/j.healun.2025.04.007","DOIUrl":"10.1016/j.healun.2025.04.007","url":null,"abstract":"","PeriodicalId":15900,"journal":{"name":"Journal of Heart and Lung Transplantation","volume":"44 8","pages":"Pages 1352-1353"},"PeriodicalIF":6.4,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144702502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical outcomes of cardiogenic shock patients supported with VA-ECMO: Insights from the Cardiogenic Shock Working Group. 心源性休克患者支持VA-ECMO的临床结果:来自心源性休克工作组的见解。
IF 6 1区 医学
Journal of Heart and Lung Transplantation Pub Date : 2025-07-24 DOI: 10.1016/j.healun.2025.07.016
Jaime Hernandez-Montfort, Kevin J John, Daniel Goldstein, Roberto Lorusso, Shashank S Sinha, Rachel Goodman, Peter Natov, Song Li, Borui Li, Manreet Kanwar, Arthur Reshad Garan, Jacob Abraham, Qiuyue Kong, Paavni Sangal, Karol Walec, Claudius Mahr, Aniket Rali, Daniel Burkhoff, Navin K Kapur
{"title":"Clinical outcomes of cardiogenic shock patients supported with VA-ECMO: Insights from the Cardiogenic Shock Working Group.","authors":"Jaime Hernandez-Montfort, Kevin J John, Daniel Goldstein, Roberto Lorusso, Shashank S Sinha, Rachel Goodman, Peter Natov, Song Li, Borui Li, Manreet Kanwar, Arthur Reshad Garan, Jacob Abraham, Qiuyue Kong, Paavni Sangal, Karol Walec, Claudius Mahr, Aniket Rali, Daniel Burkhoff, Navin K Kapur","doi":"10.1016/j.healun.2025.07.016","DOIUrl":"10.1016/j.healun.2025.07.016","url":null,"abstract":"<p><strong>Background: </strong>Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) use for cardiogenic shock (CS) is increasing worldwide despite conflicting results from randomized trials, which focused on myocardial infarction-related CS (MI-CS).</p><p><strong>Methods: </strong>We performed a retrospective analysis of the Cardiogenic Shock Working Group multicenter registry to assess outcomes in CS in those supported with VA-ECMO. Continuous variables were presented as mean±SD or median+IQR for normal/non-normal distributions. Group comparisons used the Student's t-test or Mann-Whitney U test for normal/non-normal data and chi-square test for proportions.</p><p><strong>Results: </strong>Between 2019 and 2023, 1,728 out of 11,244 CS patients (15.3%) received VA-ECMO. Median age was 58 years, and 69.9% were male. Etiologies of shock were heart failure (HF-CS: 45%), myocardial infarction (MI-CS; 34%), and other-CS (22%). Mortality was 51% and higher for MI-CS (60% vs 42%, MI vs HF-CS, p < 0.01). Heart replacement therapy was more common among HF-CS patients (24% vs 7%, HF vs MI-CS, p < 0.01); 71% and 43% of HF- and MI-CS underwent cardiac transplantation. VA-ECMO was placed in a non-OR site in 74% of patients, predominantly with peripheral cannulation (71%). Distal perfusion catheters were used in 34% of VA-ECMO cases. In 71% of patients >1 MCS device was used during hospitalization. Complications included acute limb ischemia (14% overall, 10% vs 17%, HF vs MI-CS, p < 0.01), bleeding (53% overall, 47% vs 56%, HF vs MI-CS, p < 0.01), and stroke (13% overall, 10% vs 16%, HF vs MI-CS, p < 0.01).</p><p><strong>Conclusions: </strong>Using a large contemporary real-world CS registry, we report high mortality and complication rates with VA-ECMO. These findings may inform future shock trial designs.</p>","PeriodicalId":15900,"journal":{"name":"Journal of Heart and Lung Transplantation","volume":" ","pages":""},"PeriodicalIF":6.0,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144718018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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