Journal of Forensic Medicine最新文献_第4页

Research Progress on Molecular Biology of Human Height Estimation. 人体身高估算的分子生物学研究进展。

Journal of Forensic Medicine Pub Date : 2023-10-25 DOI: 10.12116/j.issn.1004-5619.2022.520301

Zhong-Hua Wang, Shu-Jin Li

引用次数: 0

[Identification of causal relationship between fibrous dysplasia of fibula and fracture： A case report]. [腓骨纤维发育不良与骨折因果关系的鉴定:1例报告]。

Journal of Forensic Medicine Pub Date : 2023-10-25 DOI: 10.12116/j.issn.1004-5619.2022.220807

Kun Zhu, Dong Gao, Lihua Fan

引用次数: 0

[Discussion on the cause of secondary traffic injury： A case report]. 【二次交通伤害成因探讨:1例报告】。

Journal of Forensic Medicine Pub Date : 2023-10-25 DOI: 10.12116/j.issn.1004-5619.2022.220613

Dandan Din, Lili Zhao, Fangfang Shi, Yating Chen, Guonan Pan

引用次数: 0

[Assessing the disability of enophthalmos with CT scanning measurement method: A case report]. [用CT扫描测量法评价眼球内陷的致残性:1例报告]。

Journal of Forensic Medicine Pub Date : 2023-10-25 DOI: 10.12116/j.issn.1004-5619.2021.210905

Qiang Li, Zhihao Fu, Xiaodong Sun, Xiaoyu Huang

引用次数: 0

Cross-Platform Application of DNA Methylation Age Estimation Model in Eastern Chinese Han Population. DNA甲基化年龄估计模型在中国东部汉族人群中的跨平台应用

Journal of Forensic Medicine Pub Date : 2023-10-25 DOI: 10.12116/j.issn.1004-5619.2022.520405

Zi-Wei Wang, Cheng-Tao Li, Xi-Ling Liu

{"title":"Cross-Platform Application of DNA Methylation Age Estimation Model in Eastern Chinese Han Population.","authors":"Zi-Wei Wang, Cheng-Tao Li, Xi-Ling Liu","doi":"10.12116/j.issn.1004-5619.2022.520405","DOIUrl":"10.12116/j.issn.1004-5619.2022.520405","url":null,"abstract":"Objectives: To evaluate the forensic application value of an age estimation model based on DNA methylation in eastern Chinese Han population, and to provide a theoretical basis for exploring age estimation models suitable for different detection platforms.Methods: According to the 6 age-related methylation sites in the published blood DNA methylation age estimation models of Chinese Han population, the DNA methylation level of 48 samples was detected by pyrosequencing and next-generation sequencing (NGS). After submitting DNA methylation levels to the age estimation model, the DNA methylation ages were predicted and compared with their real ages.Results: The 6 DNA methylation sites in both detection techniques were age-related, with an R2 of 0.85 and a median absolute deviation (MAD) of 4.81 years when using pyrosequencing；with an R2 of 0.84 and MAD of 4.41 years when using NGS.Conclusions: The blood DNA methylation age estimation model can be used under pyrosequencing and multi-purpose regional methylation enrichment sequencing technology based on NGS and it can accurately estimate the age.","PeriodicalId":15899,"journal":{"name":"Journal of Forensic Medicine","volume":"39 5","pages":"441-446"},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138434229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Qualitative and Quantitative Analysis of Five Indoles or Indazole Amide Synthetic Cannabinoids in Suspected E-Cigarette Oil by GC-MS. 气相色谱-质谱联用分析疑似电子烟油中5种吲哚或吲哚酰胺类合成大麻素。

Journal of Forensic Medicine Pub Date : 2023-10-25 DOI: 10.12116/j.issn.1004-5619.2022.320101

Cui-Mei Liu, Wei Jia, Chun-Hui Song, Zhen-Hua Qian, Zhen-Dong Hua, Yue-Meng Chen

{"title":"Qualitative and Quantitative Analysis of Five Indoles or Indazole Amide Synthetic Cannabinoids in Suspected E-Cigarette Oil by GC-MS.","authors":"Cui-Mei Liu, Wei Jia, Chun-Hui Song, Zhen-Hua Qian, Zhen-Dong Hua, Yue-Meng Chen","doi":"10.12116/j.issn.1004-5619.2022.320101","DOIUrl":"10.12116/j.issn.1004-5619.2022.320101","url":null,"abstract":"Objectives: To establish the GC-MS qualitative and quantitative analysis methods for the synthetic cannabinoids, its main matrix and additives in suspicious electronic cigarette (e-cigarette) oil samples.Methods: The e-cigarette oil samples were analyzed by GC-MS after diluted with methanol. Synthetic cannabinoids, its main matrix and additives in e-cigarette oil samples were qualitatively analyzed by the characteristic fragment ions and retention time. The synthetic cannabinoids were quantitatively analyzed by using the selective ion monitoring mode.Results: The linear range of each compound in GC-MS quantitative method was 0.025-1 mg/mL, the matrix recovery rate was 94%-103%, the intra-day precision relative standard deviations (RSD) was less than 2.5%, and inter-day precision RSD was less than 4.0%. Five indoles or indazole amide synthetic cannabinoids were detected in 25 e-cigarette samples. The main matrixes of e-cigarette samples were propylene glycol and glycerol. Additives such as N,2,3-trimethyl-2-isopropyl butanamide (WS-23), glycerol triacetate and nicotine were detected in some samples. The content range of synthetic cannabinoids in 25 e-cigarette samples was 0.05%-2.74%.Conclusions: The GC-MS method for synthesizing cannabinoid, matrix and additive in e-cigarette oil samples has good selectivity, high resolution, low detection limit, and can be used for simultaneous qualitative and quantitative analysis of multiple components; The explored fragment ion fragmentation mechanism of the electron bombardment ion source of indole or indoxamide compounds helps to identify such substances or other compounds with similar structures in cases.","PeriodicalId":15899,"journal":{"name":"Journal of Forensic Medicine","volume":"39 5","pages":"457-464"},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138434245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Research Progress and Forensic Application of Human Vascular Finite Element Modeling and Biomechanics. 人体血管有限元建模与生物力学研究进展及法医应用。

Journal of Forensic Medicine Pub Date : 2023-10-25 DOI: 10.12116/j.issn.1004-5619.2021.411103

Yong Zeng, Dong-Hua Zou, Ying Fan, Qing Xu, Lu-Yang Tao, Yi-Jiu Chen, Zheng-Dong Li

引用次数: 0

Application of SNaPshot Technology in Semen-Specific cSNP Genetic Marker. SNaPshot技术在精液特异性cSNP遗传标记中的应用。

Journal of Forensic Medicine Pub Date : 2023-10-25 DOI: 10.12116/j.issn.1004-5619.2021.510804

Rui-Yang Tao, Shou-Yu Wang, Chun-Yan Yuan, Ruo-Cheng Xia, Cheng-Tao Li

{"title":"Application of SNaPshot Technology in Semen-Specific cSNP Genetic Marker.","authors":"Rui-Yang Tao, Shou-Yu Wang, Chun-Yan Yuan, Ruo-Cheng Xia, Cheng-Tao Li","doi":"10.12116/j.issn.1004-5619.2021.510804","DOIUrl":"10.12116/j.issn.1004-5619.2021.510804","url":null,"abstract":"Objectives: To explore the feasibility of genetic marker detection of semen-specific coding region single nucleotide polymorphism (cSNP) based on SNaPshot technology in semen stains and mixed body fluid identification.Methods: Genomic DNA (gDNA) and total RNA were extracted from 16 semen stains and 11 mixtures composed of semen and venous blood, and the total RNA was reverse transcribed into complementary DNA (cDNA). The cSNP genetic markers were screened on the validated semen-specific mRNA coding genes. The cSNP multiplex detection system based on SNaPshot technology was established, and samples were genotyped by capillary electrophoresis (CE).Results: A multiplex detection system containing 5 semen-specific cSNPs was successfully established. In 16 semen samples, except the cSNP located in the TGM4 gene showed allele loss in cDNA detection results, the gDNA and cDNA typing results of other cSNPs were highly consistent. When detecting semen-venous blood mixtures, the results of cSNP typing detected were consistent with the genotype of semen donor and were not interfered by the genotype of venous blood donor.Conclusions: The method of semen-specific cSNPs detection by SNaPshot technology method can be applied to the genotyping of semen (stains) and provide information for determining the origin of semen in mixed body fluids (stains).","PeriodicalId":15899,"journal":{"name":"Journal of Forensic Medicine","volume":"39 5","pages":"465-470"},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138434227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Research Progress and Application Prospect of Facial Micro-Expression Analysis in Forensic Psychiatry. 面部微表情分析在法医精神病学中的研究进展及应用前景。

Journal of Forensic Medicine Pub Date : 2023-10-25 DOI: 10.12116/j.issn.1004-5619.2022.120104

Wen Li, Hao-Zhe Li, Chen Chen, Wei-Xiong Cai

引用次数: 0

[Forensic identification of lung contusion and laceration complicated with multiple pseudocysts： A case report]. [肺挫伤撕裂伤合并多发假性囊肿的法医鉴定1例]。

Journal of Forensic Medicine Pub Date : 2023-10-25 DOI: 10.12116/j.issn.1004-5619.2021.211006

Yongming An, Zhiwei Zhang, Guopeng Guan

引用次数: 0