{"title":"[Identification of causal relationship between fibrous dysplasia of fibula and fracture: A case report].","authors":"琨 朱, 东 高, 利 华 范","doi":"10.12116/j.issn.1004-5619.2022.220807","DOIUrl":"10.12116/j.issn.1004-5619.2022.220807","url":null,"abstract":"李某,男,28岁,某年12月6日在篮球比赛中右小腿与他人碰撞后倒地,临床诊断为右腓骨病理性骨折。现委托单位要求对本次外伤与李某右腓骨病理性骨折之间的因果关系及参与程度进行法医临床鉴定。.","PeriodicalId":15899,"journal":{"name":"Journal of Forensic Medicine","volume":"39 5","pages":"522-524"},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138434223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Research Progress on Molecular Biology of Human Height Estimation.","authors":"Zhong-Hua Wang, Shu-Jin Li","doi":"10.12116/j.issn.1004-5619.2022.520301","DOIUrl":"10.12116/j.issn.1004-5619.2022.520301","url":null,"abstract":"<p><p>As an important anthropometric characteristic, human height not only contributes to the recognition of other anthropological characteristics and genetic risk factors, but also is an important part of forensic DNA phenotyping studies. Accurate estimation of height can provide more complete information about the phenotype of suspects and provide help to solve cases. In recent years, having benefited from the rapid development of molecular biological techniques and bioinformatics, height-related genetics research has made some progress. This paper describes the research progress of human height estimation from the genetic variation and the epigenetic inheritance perspectives and looks into the future research direction.</p>","PeriodicalId":15899,"journal":{"name":"Journal of Forensic Medicine","volume":"39 5","pages":"487-492"},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138434248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Discussion on the cause of secondary traffic injury: A case report].","authors":"丹 丹 林, 莉 莉 赵, 芳 芳 施, 雅 婷 陈, 国 南 潘","doi":"10.12116/j.issn.1004-5619.2022.220613","DOIUrl":"10.12116/j.issn.1004-5619.2022.220613","url":null,"abstract":"被鉴定人,男,35岁,某年10月26日03:50,驾驶轻型厢式货车碰撞道路中央绿化带及路灯后受伤,具体伤情不详。同日04:15,该男在被救护车送医途中又遭遇车辆追尾交通事故。被鉴定人诉在救护车追尾事故中,未从救护车内的担架上摔下来,但救护车内仪器设备掉落砸伤左下肢,具体砸伤部位不明。法院委托要求对第二次交通事故能否造成被鉴定人左下肢损伤进行鉴定。.","PeriodicalId":15899,"journal":{"name":"Journal of Forensic Medicine","volume":"39 5","pages":"530-534"},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138434220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cross-Platform Application of DNA Methylation Age Estimation Model in Eastern Chinese Han Population.","authors":"Zi-Wei Wang, Cheng-Tao Li, Xi-Ling Liu","doi":"10.12116/j.issn.1004-5619.2022.520405","DOIUrl":"10.12116/j.issn.1004-5619.2022.520405","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the forensic application value of an age estimation model based on DNA methylation in eastern Chinese Han population, and to provide a theoretical basis for exploring age estimation models suitable for different detection platforms.</p><p><strong>Methods: </strong>According to the 6 age-related methylation sites in the published blood DNA methylation age estimation models of Chinese Han population, the DNA methylation level of 48 samples was detected by pyrosequencing and next-generation sequencing (NGS). After submitting DNA methylation levels to the age estimation model, the DNA methylation ages were predicted and compared with their real ages.</p><p><strong>Results: </strong>The 6 DNA methylation sites in both detection techniques were age-related, with an <i>R</i><sup>2</sup> of 0.85 and a median absolute deviation (MAD) of 4.81 years when using pyrosequencing;with an <i>R</i><sup>2</sup> of 0.84 and MAD of 4.41 years when using NGS.</p><p><strong>Conclusions: </strong>The blood DNA methylation age estimation model can be used under pyrosequencing and multi-purpose regional methylation enrichment sequencing technology based on NGS and it can accurately estimate the age.</p>","PeriodicalId":15899,"journal":{"name":"Journal of Forensic Medicine","volume":"39 5","pages":"441-446"},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138434229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Qualitative and Quantitative Analysis of Five Indoles or Indazole Amide Synthetic Cannabinoids in Suspected E-Cigarette Oil by GC-MS.","authors":"Cui-Mei Liu, Wei Jia, Chun-Hui Song, Zhen-Hua Qian, Zhen-Dong Hua, Yue-Meng Chen","doi":"10.12116/j.issn.1004-5619.2022.320101","DOIUrl":"10.12116/j.issn.1004-5619.2022.320101","url":null,"abstract":"<p><strong>Objectives: </strong>To establish the GC-MS qualitative and quantitative analysis methods for the synthetic cannabinoids, its main matrix and additives in suspicious electronic cigarette (e-cigarette) oil samples.</p><p><strong>Methods: </strong>The e-cigarette oil samples were analyzed by GC-MS after diluted with methanol. Synthetic cannabinoids, its main matrix and additives in e-cigarette oil samples were qualitatively analyzed by the characteristic fragment ions and retention time. The synthetic cannabinoids were quantitatively analyzed by using the selective ion monitoring mode.</p><p><strong>Results: </strong>The linear range of each compound in GC-MS quantitative method was 0.025-1 mg/mL, the matrix recovery rate was 94%-103%, the intra-day precision relative standard deviations (RSD) was less than 2.5%, and inter-day precision RSD was less than 4.0%. Five indoles or indazole amide synthetic cannabinoids were detected in 25 e-cigarette samples. The main matrixes of e-cigarette samples were propylene glycol and glycerol. Additives such as <i>N</i>,2,3-trimethyl-2-isopropyl butanamide (WS-23), glycerol triacetate and nicotine were detected in some samples. The content range of synthetic cannabinoids in 25 e-cigarette samples was 0.05%-2.74%.</p><p><strong>Conclusions: </strong>The GC-MS method for synthesizing cannabinoid, matrix and additive in e-cigarette oil samples has good selectivity, high resolution, low detection limit, and can be used for simultaneous qualitative and quantitative analysis of multiple components; The explored fragment ion fragmentation mechanism of the electron bombardment ion source of indole or indoxamide compounds helps to identify such substances or other compounds with similar structures in cases.</p>","PeriodicalId":15899,"journal":{"name":"Journal of Forensic Medicine","volume":"39 5","pages":"457-464"},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138434245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Research Progress and Forensic Application of Human Vascular Finite Element Modeling and Biomechanics.","authors":"Yong Zeng, Dong-Hua Zou, Ying Fan, Qing Xu, Lu-Yang Tao, Yi-Jiu Chen, Zheng-Dong Li","doi":"10.12116/j.issn.1004-5619.2021.411103","DOIUrl":"10.12116/j.issn.1004-5619.2021.411103","url":null,"abstract":"<p><p>The finite element method (FEM) is a mathematical method for obtaining approximate solutions to a wide variety of engineering problems. With the development of computer technology, it is gradually applied to the study of biomechanics of human body. The application of the combination of FEM and biomechanics in exploring the relationship between vascular injury and disease, and pathological mechanisms will be a technological innovation for traditional forensic medicine. This paper reviews the construction and development of human vascular FEM modeling, and its research progress on the vascular biomechanics. This paper also looks to the application prospects of FEM modeling in forensic pathology.</p>","PeriodicalId":15899,"journal":{"name":"Journal of Forensic Medicine","volume":"39 5","pages":"471-477"},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138434247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Forensic identification of lung contusion and laceration complicated with multiple pseudocysts: A case report].","authors":"明 安永, 志 威 张, 国 鹏 关","doi":"10.12116/j.issn.1004-5619.2021.211006","DOIUrl":"10.12116/j.issn.1004-5619.2021.211006","url":null,"abstract":"孟某,女,19岁,某年8月4日因“交通事故致左肩部、胸部疼痛,活动受限2 h”就诊。10月4日对孟某的损伤程度进行鉴定。.","PeriodicalId":15899,"journal":{"name":"Journal of Forensic Medicine","volume":"39 5","pages":"519-522"},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138434222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Jinci declaration of Chinese forensic medicine].","authors":"会 中国法医学, 会 教育部高等学校法医学类专业教学指导委员","doi":"10.12116/j.issn.1004-5619.2023.431002","DOIUrl":"10.12116/j.issn.1004-5619.2023.431002","url":null,"abstract":"2023年10月16日,全国法医学领域的高校、科研机构以及最高人民法院、最高人民检察院、教育部、公安部、司法部和国家卫生健康委员会等部门的四百余位专家齐聚山西晋祠,共同参加“中国法医学科学技术发展论坛”。论坛期间,专家们回顾总结四十年来法医学教育、科研及社会服务成果,擘画新时代法医学事业发展未来,提出法医学新概念、新内涵和新定位,达成共识,由中国法医学会,教育部高等学校法医学类专业教学指导委员会联合发布“中国法医学 晋祠宣言”。.","PeriodicalId":15899,"journal":{"name":"Journal of Forensic Medicine","volume":"39 5","pages":"431-432"},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138434225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rui-Yang Tao, Shou-Yu Wang, Chun-Yan Yuan, Ruo-Cheng Xia, Cheng-Tao Li
{"title":"Application of SNaPshot Technology in Semen-Specific cSNP Genetic Marker.","authors":"Rui-Yang Tao, Shou-Yu Wang, Chun-Yan Yuan, Ruo-Cheng Xia, Cheng-Tao Li","doi":"10.12116/j.issn.1004-5619.2021.510804","DOIUrl":"10.12116/j.issn.1004-5619.2021.510804","url":null,"abstract":"<p><strong>Objectives: </strong>To explore the feasibility of genetic marker detection of semen-specific coding region single nucleotide polymorphism (cSNP) based on SNaPshot technology in semen stains and mixed body fluid identification.</p><p><strong>Methods: </strong>Genomic DNA (gDNA) and total RNA were extracted from 16 semen stains and 11 mixtures composed of semen and venous blood, and the total RNA was reverse transcribed into complementary DNA (cDNA). The cSNP genetic markers were screened on the validated semen-specific mRNA coding genes. The cSNP multiplex detection system based on SNaPshot technology was established, and samples were genotyped by capillary electrophoresis (CE).</p><p><strong>Results: </strong>A multiplex detection system containing 5 semen-specific cSNPs was successfully established. In 16 semen samples, except the cSNP located in the <i>TGM4</i> gene showed allele loss in cDNA detection results, the gDNA and cDNA typing results of other cSNPs were highly consistent. When detecting semen-venous blood mixtures, the results of cSNP typing detected were consistent with the genotype of semen donor and were not interfered by the genotype of venous blood donor.</p><p><strong>Conclusions: </strong>The method of semen-specific cSNPs detection by SNaPshot technology method can be applied to the genotyping of semen (stains) and provide information for determining the origin of semen in mixed body fluids (stains).</p>","PeriodicalId":15899,"journal":{"name":"Journal of Forensic Medicine","volume":"39 5","pages":"465-470"},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138434227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}