Journal of Integrative Nephrology and Andrology最新文献_第2页

Urinary tract infection in nephrotic children: A cross-sectional study 肾病儿童尿路感染:一项横断面研究

Journal of Integrative Nephrology and Andrology Pub Date : 2020-01-01 DOI: 10.4103/jina.jina_5_20

S. Bakshi, Subhendu S. Samanta

{"title":"Urinary tract infection in nephrotic children: A cross-sectional study","authors":"S. Bakshi, Subhendu S. Samanta","doi":"10.4103/jina.jina_5_20","DOIUrl":"https://doi.org/10.4103/jina.jina_5_20","url":null,"abstract":"Background and Objectives: Nephrotic syndrome, characterized by the presence of heavy proteinuria, hypoalbuminemia, edema, and hyperlipidemia, is a common renal disorder in pediatric population. The aim of this study was to find out the prevalence of urinary tract infection (UTI) in nephrotic syndrome, bacterial etiologies, and antibiotic sensitivity pattern. Subjects and Methods: After matching the criteria, 82 cases were taken for this prospective, single-center, observational study. The diagnosis was confirmed by bacterial culture. This is an institution-based, cross-sectional, descriptive observational study. All newly diagnosed and relapse cases of nephrotic syndrome based on the inclusion exclusion criteria were included in the study. Respondent was either of the parents or caregiver of the study subjects. Analysis of all data was done by appropriate statistical software (SPSS-23). Results: Among 82 participants evaluated with nephrotic syndrome, 29.3% of participants had UTI, majority (66.7%) were asymptomatic, and 33.3% were symptomatic. Significant microscopic hematuria was found in 20.7% of study subjects and significant pyuria was found in 58.54%. Majority (33.3%) of UTIs were caused by Escherichia coli, followed by Klebsiella 25%, Proteus 16.7%, and Staphylococcus aureus 12.5%, and Citrobacter, Acinetobacter, and mixed growth were found in 4.2% each. The mean serum cholesterol of group with UTI was 422.13 ± 34.65 and group without UTI was 307.43 ± 26.13. The variation among the two groups was found to be statistically significant (P = 0.0001). Conclusions: The children with nephrotic syndrome are frequently predisposed to UTI, and in most cases, it is asymptomatic and often undiagnosed. Higher serum cholesterol level may predispose the nephrotic child for UTI.","PeriodicalId":158840,"journal":{"name":"Journal of Integrative Nephrology and Andrology","volume":"65 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115439423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Hypomagnesemia: Hidden key of life and primary event for hypovitaminosis D and hypoalbuminemia in hemodialysis 低镁血症:血液透析中维生素D缺乏症和低白蛋白血症的生命隐藏关键和主要事件

Journal of Integrative Nephrology and Andrology Pub Date : 2019-07-01 DOI: 10.4103/jina.jina_18_18

M. Malaki

引用次数: 0

X-linked alport syndrome presenting as bilateral lenticonus and end-stage renal disease x连锁alport综合征表现为双侧晶状体和终末期肾脏疾病

Journal of Integrative Nephrology and Andrology Pub Date : 2019-07-01 DOI: 10.4103/jina.jina_19_18

Mritunjay Kumar, S. Sushanth Kumar, A. Sharma, R. Kumari

引用次数: 0

Kidney disease screening in a group of female health personnel: Who are often missing? 一组女性卫生人员的肾脏疾病筛查:谁经常被遗漏?

Journal of Integrative Nephrology and Andrology Pub Date : 2019-07-01 DOI: 10.4103/jina.jina_20_18

M. Kashem, R. Biswas, K. Jewel

{"title":"Kidney disease screening in a group of female health personnel: Who are often missing?","authors":"M. Kashem, R. Biswas, K. Jewel","doi":"10.4103/jina.jina_20_18","DOIUrl":"https://doi.org/10.4103/jina.jina_20_18","url":null,"abstract":"Background and Objective: Data on early-stage of chronic kidney disease (CKD) and the prevalence of CKD are very limited, especially more scanty in our female population. Hence, data from a kidney screening program organized at the Chattagram Maa-O-Shishu Hospital premises in connection with the observance of World Kidney Day 2018 were looked at for renal function among a group of female health personnel. Methods: This was a cross-sectional study among a group of female health personnel working at the hospital. Age, body weight, height, Body mass index (BMI), and blood pressure were documented, and serum creatinine was measured at a single sitting. The kidney function was estimated by calculating the glomerular filtration rate (GFR) using the Modified Diet in Renal Disease formula. Kidney function was classified according to estimated GFR (eGFR) and Kidney Disease Outcomes Quality Initiative (K/DOQI) guidelines. Results: A total of 101 female health personnel were studied – physicians - 23; nurses - 45, and health assistants - 33. Majority participants (51%) were in the age group of 20–29 years; 5% were <20-year-old; and 9.9% were more than 40-year-old. The distribution of eGFR was symmetrical, with the majority (82%) of individuals in the 60–89 mL/min category; 11.88% had 30–59 mL/min category and only 5.9% of the study population had eGFR >90 mL/min category. An inverse relation between the age and eGFR and a direct relation between the BMI and eGFR were observed in the study. Conclusion: The results indicate that low GFR levels and consequently a high burden of likely CKD are prevailing in our female population. It is not clear whether such observations are the result of the transportability problems associated with the GFR prediction equations or with the suitability of K/DOQI guidelines for the classification of CKD in our population or both. Well-planned, larger, and community- and hospital-based studies are warranted to clarify these issues, especially for our female population.","PeriodicalId":158840,"journal":{"name":"Journal of Integrative Nephrology and Andrology","volume":"79 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114461477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

25(OH) vitamin D: Serum levels and related factors in hemodialysis patients 25(OH)维生素D:血液透析患者血清水平及相关因素

Journal of Integrative Nephrology and Andrology Pub Date : 2019-01-01 DOI: 10.4103/jina.jina_9_18

D. Nascimento, M. Luz, K. Remor, T. Sakae, M. Machado

{"title":"25(OH) vitamin D: Serum levels and related factors in hemodialysis patients","authors":"D. Nascimento, M. Luz, K. Remor, T. Sakae, M. Machado","doi":"10.4103/jina.jina_9_18","DOIUrl":"https://doi.org/10.4103/jina.jina_9_18","url":null,"abstract":"Background and Objective: Advanced chronic renal failure leads to changes in calcium metabolism that cause disturbances in the parathyroid, vascular system, and bones. The 25(OH) Vitamin D plays a key role in regulating calcium metabolism and preventing these complications. The objective of this study was to determine 25(OH) Vitamin D levels in dialysis patients and to relate to clinical and sociodemographic characteristics. Methods: This was a cross-sectional study. The data collection was given by interview and consultation in electronic records, and the dosage of 25(OH) Vitamin D was performed on heparinized plasma samples collected at the beginning of the dialysis session. Results: Of the 77 patients studied, noted that seven (9.1%) showed poor values of 25(OH) Vitamin D and 19 (24.7%) showed insufficient values. As for the presence of comorbidities, 31 (40.3%) reported having diabetes mellitus, and 54 (70.1%) reported having arterial hypertension. It was also observed that the serum levels of 25(OH) Vitamin D are inferior in the carriers of diabetes mellitus and decrease with the increase of age and with the elevation of serum creatinine. The use of Vitamin D supplements presented positive correlation with serum calcium levels. Conclusion: The insufficiency of 25(OH) Vitamin D is frequent in dialysis patients especially in the carriers of diabetes mellitus.","PeriodicalId":158840,"journal":{"name":"Journal of Integrative Nephrology and Andrology","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126391372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Aggressive angiomyxoma of the scrotum in a man: A case report and literature review of 73 cases of aggressive angiomyxoma in men 男性阴囊侵袭性血管黏液瘤:73例男性侵袭性血管黏液瘤病例报告及文献复习

Journal of Integrative Nephrology and Andrology Pub Date : 2019-01-01 DOI: 10.4103/jina.jina_14_18

M. Al-Mendalawi

引用次数: 0

Sertraline - Associated acute urinary retention in a patient with benign prostatic hyperplasia 良性前列腺增生患者舍曲林相关性急性尿潴留1例

Journal of Integrative Nephrology and Andrology Pub Date : 2019-01-01 DOI: 10.4103/jina.jina_16_18

N. Uvais, T. Mohammed

引用次数: 0

Clinical profile of acute kidney injury in a tertiary care center in the Tropical Region 急性肾损伤在热带地区三级保健中心的临床概况

Journal of Integrative Nephrology and Andrology Pub Date : 2018-10-01 DOI: 10.4103/jina.jina_15_18

Utkarsh Rajesh Patel, A. Pasari, M. Balwani, A. Bhawane, P. Tolani, Shaurya Acharya

{"title":"Clinical profile of acute kidney injury in a tertiary care center in the Tropical Region","authors":"Utkarsh Rajesh Patel, A. Pasari, M. Balwani, A. Bhawane, P. Tolani, Shaurya Acharya","doi":"10.4103/jina.jina_15_18","DOIUrl":"https://doi.org/10.4103/jina.jina_15_18","url":null,"abstract":"Objective: The objectives of the study were to study etiology, manifestations, and outcome of acute kidney disease in the tropical region in a tertiary care center. Materials and Methods: In the present prospective study, patients with acute kidney disease admitted to JNMC, Wardha, India, between January 2017 and December 2017 were studied with a detailed history, general physical examination, and systemic examination. Data were collected and analyzed. Statistical analysis was performed using descriptive and inferential statistics using the Chi-square test and Student's unpaired t-test and software used in the analysis was SPSS 22.0 version and Graph Pad Prism 6.0 version. Results: This study showed male-to-female ratio of 1.8:1. Maximum incidence was seen in patients aged >60 years. As per the Kuppuswamy's scale, most of the patients belonged to lower-middle and upper lower class. The study showed various etiological factors associated with acute kidney injuries (AKIs) such as renal causes (most common), heart failure, respiratory failure, cirrhosis, malaria, snake bite, acute gastroenteritis, poisoning, drug nephrotoxicity, and sepsis. Common symptoms were oliguria followed by pedal edema and dyspnea. The most common comorbid illness was hypertension followed by diabetes mellitus which may have made them prone to AKI. About 81.42% of patients survived and 18.58% expired. Of 70, 56 patients were managed conservatively, whereas 14 underwent hemodialysis. Mean duration of hospitalization was 11.01 ± 8.60 days. Conclusion: Intrinsic renal causes followed by heart failure were the common causes of AKI as against infective causes a few years earlier. This shows the changing trend of AKI causes in a developing nation. Average duration of hospitalization was 11 days in the study.","PeriodicalId":158840,"journal":{"name":"Journal of Integrative Nephrology and Andrology","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122412709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Study of some electrocardiographic and echocardiographic data in toddelers and children with primary glomerulonephropathy 幼儿及儿童原发性肾小球肾病心电图及超声心动图资料的研究

Journal of Integrative Nephrology and Andrology Pub Date : 2018-10-01 DOI: 10.4103/jina.jina_36_17

M. El-Gamasy, Walid El-Shehabi

{"title":"Study of some electrocardiographic and echocardiographic data in toddelers and children with primary glomerulonephropathy","authors":"M. El-Gamasy, Walid El-Shehabi","doi":"10.4103/jina.jina_36_17","DOIUrl":"https://doi.org/10.4103/jina.jina_36_17","url":null,"abstract":"Background and Objective: Primary glomerulonephropathy mainly acute poststreptococcal glomerulonephritis (APSGN) is the most common cause of hypertensive heart failure in the pediatric age as APSGN may involve various systems including cardiovascular system. There are few research publications on electrocardiographic (ECG) and echocardiographic (two-dimensional [2D]-echo) data in childrenwith primary glomerulonephropathy. The aim is to study some ECG and 2D-echo data in Egyptian pediatric patients with ANS). Subjects and Methods: Sixty children with ANS were included and subjected to clinical, laboratory, ECG for corrected QT (QTc) interval and 2D echocardiographic study on admission and repeated at 6 and 12 weeks using GE Vivid 7 (GE Medical System, Horten, Norway with a 3.5-MHz multifrequency transducer) to measure left ventricular ejection fraction (LVEF), left atrium to aorta ratio and E/A ratio. Results: Prolonged QTc interval was reported in 22 patients (37%), of whom 18 had hypertension. Fourteen of the 60 children had LVEF <60%. The same children also had left atrium/aorta ratio >2 and E/A ratio more than two. LVEF became within normal values by 1½ month (6 weeks) in 12 patients, two become normal by three months of follow-up. Four (28.6%) from 14 children with low LVEF had normal arterial blood pressure. All the 14 children had completely recovered on follow-up period of 3 months. Conclusion: Changes in ECG and echo data which were reported in the acute phase of ANS appear to be temporary (transient) as they became within normal values in almost all children by 12 weeks period of follow-up. Although elevated blood pressure was the most common etiology of congestive heart failure in children with ANS, the impact of primary myocardial functional disturbance could also be put into consideration.","PeriodicalId":158840,"journal":{"name":"Journal of Integrative Nephrology and Andrology","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125248574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

To study the prevalence of thyroid disorders in chronic renal disease patients 探讨慢性肾病患者甲状腺功能障碍的患病率

Journal of Integrative Nephrology and Andrology Pub Date : 2018-10-01 DOI: 10.4103/jina.jina_13_18

Upendra Gupta, Apoorva Jain, Prashant Prakash, P. Agrawal, Ravi Kumar, M. Farooqui

{"title":"To study the prevalence of thyroid disorders in chronic renal disease patients","authors":"Upendra Gupta, Apoorva Jain, Prashant Prakash, P. Agrawal, Ravi Kumar, M. Farooqui","doi":"10.4103/jina.jina_13_18","DOIUrl":"https://doi.org/10.4103/jina.jina_13_18","url":null,"abstract":"Background and Objectives: The high prevalence of thyroid dysfunction in chronic kidney disease (CKD) patients reveals significant association between CKD progression and thyroid dysfunction. The aim was to study the thyroid dysfunction in patients of CKD for the prevalence of subclinical hypothyroidism (SCH) and clinical hypothyroidism and study the correlation between thyroid dysfunction and severity of renal diseases. In view of the variability of thyroid profile in CKD patients in previous studies, a prospective study of various thyroid function has been undertaken to establish a correlation if any between thyroid dysfunction and severity of renal diseases. Materials and Methods: A total of 100 patients with CKD on conservative management fulfilling the criteria for CKD who were admitted at the Department of Medicine, SNMC, Agra, Uttar Pradesh, India, during the period of July 2016–June 2017, were selected in this study. Descriptive analysis of the collected data was done and association of various parameters with the presence or absence of SCH or overt hypothyroidism was studied using Chi-square test and correlated. Results: Results showed that out of the 100 patients with CKD, 53 patients had thyroid dysfunction which accounted for 53%. The prevalence of SCH and clinical hypothyroidism was 33% and 20%, respectively. The number of patients with hypothyroidism progressively increased with increased severity of renal failure. Conclusions: We observed a high prevalence of thyroid dysfunction in our CKD patients and revealed significant association between CKD progression and thyroid dysfunction.","PeriodicalId":158840,"journal":{"name":"Journal of Integrative Nephrology and Andrology","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123922343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6