Journal of Integrative Nephrology and Andrology最新文献_第10页

Polysaccharide Sulfate-induced Priapism: A Report of 3 Cases 多糖硫酸盐致阴茎勃起障碍3例报告

Journal of Integrative Nephrology and Andrology Pub Date : 2016-04-01 DOI: 10.4103/2394-2916.181222

D. Gong

引用次数: 1

A Case of Sarcoidosis Associated with Recurrent Many Urinary Tract Calculi Caused by Hypercalcemia 高钙血症致结节病合并复发性多路尿路结石1例

Journal of Integrative Nephrology and Andrology Pub Date : 2016-04-01 DOI: 10.4103/2394-2916.181221

A. Tanaka, Yuichi Ito, N. Tanaka

引用次数: 0

Isoniazid-Induced Cerebellitis and Psychosis in Chronic Kidney Disease Patient with Tubercular Pleural Effusion 慢性肾病结核性胸腔积液患者异烟肼所致小脑炎和精神病

Journal of Integrative Nephrology and Andrology Pub Date : 2016-04-01 DOI: 10.4103/2394-2916.181220

V. K. Binwal, Thabish Syed, Dilip Ahir

引用次数: 3

Crossing Renal Vessel Causing Ureteropelvic Junction Obstruction in Children 儿童肾血管交叉引起肾盂输尿管连接处梗阻

Journal of Integrative Nephrology and Andrology Pub Date : 2016-04-01 DOI: 10.4103/2394-2916.181215

A. Guven

引用次数: 2

Proteinuria: A Cross Road Where the Complement and the Plasminogen-plasmin Systems Meet 蛋白尿:补体和纤溶酶原-纤溶酶系统相遇的十字路口

Journal of Integrative Nephrology and Andrology Pub Date : 2016-04-01 DOI: 10.4103/2394-2916.181217

H. Trimarchi, C. Duboscq

{"title":"Proteinuria: A Cross Road Where the Complement and the Plasminogen-plasmin Systems Meet","authors":"H. Trimarchi, C. Duboscq","doi":"10.4103/2394-2916.181217","DOIUrl":"https://doi.org/10.4103/2394-2916.181217","url":null,"abstract":"Proteinuria is the hallmark of nephrotic syndrome and a surrogate of progression of renal disease and a risk factor of cardiovascular morbidity. Once proteinuria occurs secondary to glomerular damage, its reabsorption at the proximal tubule causes a constant interstitial inflammation that will eventually lead to a graduate loss of kidney function due to fibrosis, ischemia and tubular atrophy. The plasminogen-plasmin system plays a local critical role in amplifying podocyte damage, deepening the generation of edema, cross-linking inflammatory components at the interstitium and determining the terminal fibrotic processes. Plasmin activity also causes inflammation through the complement system. The interaction between the complement and the plasminogen-plasmin systems is critical in the progression of interstitial inflammation. Plasmin is capable of cleaving C3 and C5 components of the complement system. Moreover, C3a and C5a fractions are chemoattractants of neutrophils and monocytes. The complement system is also involved in microvascular thrombosis contributing to glomerular sclerosis and interstitial fibrosis through ischemic processes. A regulator of plasmin activity is plasminogen activator inhibitor-1, a leading molecule involved in fibrosis and sclerosis, particularly augmented in glomerulopathies. Unraveling the interactions between the plasminogen-plasmin and complement systems will undoubtedly lead to more specific therapies for glomerular diseases.","PeriodicalId":158840,"journal":{"name":"Journal of Integrative Nephrology and Andrology","volume":"93 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133383020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

The Diagnostic Algorithm Patients Examination with Penile Deformation 阴茎变形患者检查的诊断算法

Journal of Integrative Nephrology and Andrology Pub Date : 2016-04-01 DOI: 10.4103/2394-2916.181216

A. Arkatov, O. Knigavko

引用次数: 0

Recent Advances in Pharmacotherapy for Peyronie′s Disease 佩罗尼氏病药物治疗的最新进展

Journal of Integrative Nephrology and Andrology Pub Date : 2016-04-01 DOI: 10.4103/2394-2916.181219

Y. Luan, Jihong Liu

{"title":"Recent Advances in Pharmacotherapy for Peyronie′s Disease","authors":"Y. Luan, Jihong Liu","doi":"10.4103/2394-2916.181219","DOIUrl":"https://doi.org/10.4103/2394-2916.181219","url":null,"abstract":"Peyronie′s disease (PD) is an acquired fibrotic disease of the penile tunica albuginea accompanied by penile pain, curvature, erectile dysfunction, and psychosocial problems. Recent evidence suggests an increasing prevalence of PD with current uncertainty of its etiology and pathophysiology. According to the natural history of PD, the disease can be divided into acute phase and fibrotic phase that greatly determines the treatment plan. Oral, intralesional medication, and topical therapy are suitable for acute phase while surgical therapy is suggested only in fibrotic phase with the formation of stable plaques. Although a number of pharmacologic agents have been evaluated in preclinical and clinical studies, a few of them can be used in the clinic with satisfactory outcome. Recent studies showed promising results in improving symptoms and limiting disease progression, especially the only Food and Drug Administration-approved collagenase Clostridium histolyticum as well as some multimodal therapies. In this study, we reviewed currently available medications and focused on recent advances in PD pharmacotherapy. However, further high-quality studies are much needed to clarify the pathogenesis of PD and, more importantly, to find out effective and safe medicines for PD treatment.","PeriodicalId":158840,"journal":{"name":"Journal of Integrative Nephrology and Andrology","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129059023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transurethral Resection of Prostate is Still the Gold Standard for Small to Moderate Sized Prostates 经尿道前列腺切除术仍然是治疗小到中等大小前列腺的金标准

Journal of Integrative Nephrology and Andrology Pub Date : 2016-04-01 DOI: 10.4103/2394-2916.181223

N. Pujari

引用次数: 7

Study of Dyslipidemia and Cystatin C Levels as a Predictive Marker of Chronic Kidney Disease in Type 2 Diabetes Mellitus Patients at a Teaching Hospital in Central India 在印度中部一家教学医院，血脂异常和胱抑素C水平作为2型糖尿病患者慢性肾脏疾病的预测指标的研究

Journal of Integrative Nephrology and Andrology Pub Date : 2016-01-01 DOI: 10.4103/2394-2916.175401

Kamal Kachhawa, M. Varma, Poonam Kachhawa, Ankita Sahu, M. Shaikh, Sanjay Kumar

{"title":"Study of Dyslipidemia and Cystatin C Levels as a Predictive Marker of Chronic Kidney Disease in Type 2 Diabetes Mellitus Patients at a Teaching Hospital in Central India","authors":"Kamal Kachhawa, M. Varma, Poonam Kachhawa, Ankita Sahu, M. Shaikh, Sanjay Kumar","doi":"10.4103/2394-2916.175401","DOIUrl":"https://doi.org/10.4103/2394-2916.175401","url":null,"abstract":"Background and Objective: Diabetic nephropathy is the most common cause of microvascular chronic complication of Type 2 diabetes mellitus (T2DM), which is associated with considerable morbidity and mortality. Chronic kidney diseases (CKD) may result from diabetes mellitus (34%), hypertension (29%), glomerulonephritis (14%), and others (23%). The present study was undertaken to explore the possibility of the serum cystatin C level as a marker of early renal impairment in T2DM patient. Materials and Methods: The study was conducted in 75 patients of T2DM and 75 healthy individuals were included as control in this study. After 12 h fasting, 8 mL venous blood sample was collected and allowed to clot for ΍ h and serum was separated. Lipid profile and cystatin C level of serum were measured by using commercially available kit of auto analyzer. Results: The level of serum cystatin C was significantly increased in T2DM patients as compared to control. In T2DM patients, high-density lipoprotein cholesterol significantly decreased (P < 0.001), while other parameters of lipid profile were significantly increased (P < 0.001) as compared to control group. Conclusion: Present study suggests that cystatin C measurement in serum is a useful, practical, noninvasive tool for the evaluation of renal involvement in the course of diabetes, especially patients, and the study also shows significant lipoprotein abnormalities in T2DM patients when compared to control.","PeriodicalId":158840,"journal":{"name":"Journal of Integrative Nephrology and Andrology","volume":"47 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114084322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

Precise Transurethral Enucleation of Prostate: New Surgery Treatment for Benign Prostate Hyperplasia 经尿道前列腺精切术:良性前列腺增生的新手术治疗方法

Journal of Integrative Nephrology and Andrology Pub Date : 2016-01-01 DOI: 10.4103/2394-2916.175395

Huan Xu, Meng Gu, Qi Chen, Yan-bo Chen, Z. Cai, Zhong Wang

引用次数: 0