Journal of Fungi最新文献

{"title":"Correction: Preisegger et al. Visualizing Oral Infection Dynamics of <i>Beauveria bassiana</i> in the Gut of <i>Tribolium castaneum</i>. <i>J. Fungi</i> 2025, <i>11</i>, 101.","authors":"Lautaro Preisegger, Juan Cruz Flecha, Fiorella Ghilini, Daysi Espin-Sánchez, Eduardo Prieto, Héctor Oberti, Eduardo Abreo, Carla Huarte-Bonnet, Nicolás Pedrini, Maria Constanza Mannino","doi":"10.3390/jof11060409","DOIUrl":"10.3390/jof11060409","url":null,"abstract":"<p><p>In the original article [...].</p>","PeriodicalId":15878,"journal":{"name":"Journal of Fungi","volume":"11 6","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12153025/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144266414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genomic Insights into <i>Neofusicoccum laricinum</i>: The Pathogen Behind Chinese Larch Shoot Blight.","authors":"Jialiang Pan, Zhijun Yu, Wenhao Dai, Chunhe Lv, Yifan Chen, Hong Sun, Jie Chen, Junxin Gao","doi":"10.3390/jof11050399","DOIUrl":"10.3390/jof11050399","url":null,"abstract":"<p><p>Larch shoot blight, caused by the fungus <i>Neofusicoccum laricinum</i>, threatens larch (<i>Larix</i> spp.) forests across northeastern China, jeopardizing both timber productivity and ecological stability. This study aimed to investigate the genomic diversity, population structure, and potential adaptive mechanisms of <i>N. laricinum</i> across contrasting climatic regions. To achieve this, we conducted whole-genome resequencing of 23 <i>N. laricinum</i> isolates collected from three major provinces-Heilongjiang, Inner Mongolia, and Jilin-that represent distinct climatic zones ranging from cold-temperate to relatively warmer regions. We identified ~219.1 K genetic variants, offering a detailed portrait of the pathogen's genomic diversity. Population structure analyses, including principal component analysis and phylogenetic tree, revealed clear genetic differentiation aligning with geographic origin and climate. Functional annotation (GO and KEGG) highlighted enrichment in metabolic, stress-response, and membrane transport pathways, suggesting potential adaptation to varied temperature regimes and environmental pressures. Moreover, region-specific variants-particularly missense and stop-gain mutations-were linked to genes involved in ATP binding, oxidoreductase activity, and cell division, underscoring the fungus's capacity for rapid adaptation. Collectively, these findings fill a critical gap in the population genetics of <i>N. laricinum</i> and lay a foundation for future disease management strategies to larch shoot blight under changing climatic conditions.</p>","PeriodicalId":15878,"journal":{"name":"Journal of Fungi","volume":"11 5","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12113642/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144150698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Impact of Epidemiological Trends and Guideline Adherence on Candidemia-Associated Mortality: A 14-Year Study in Northeastern Italy.","authors":"Fabiana Dellai, Alberto Pagotto, Francesco Sbrana, Andrea Ripoli, Giacomo Danieli, Alberto Colombo, Denise D'Elia, Monica Geminiani, Simone Giuliano, Assunta Sartor, Carlo Tascini","doi":"10.3390/jof11050400","DOIUrl":"10.3390/jof11050400","url":null,"abstract":"<p><p>Invasive candidiasis represents a major global health concern, with incidence and mortality rates expected to rise due to medical advancements and unavoidable risk factors. This retrospective, multicentric study was conducted in eight hospitals in a northeastern Italian region, enrolling adult patients diagnosed with candidemia from 1 January 2018 to 31 December 2022. Epidemiological trends and clinical characteristics were analyzed and compared to those from a prior regional study (2009-2011), allowing a fourteen-year comparative evaluation. A shift in species distribution was observed, with a decline in <i>Candida albicans</i> (from 65.7% to 57.8%) and a rise in non-<i>albicans</i> species, particularly the <i>Candida parapsilosis</i> complex (from 16.1% to 18.2%). Guideline adherence was assessed applying the EQUAL <i>Candida</i> score; scores ≥ than 11.5 were independently associated with improved in-hospital survival (HR 3.51, <i>p</i> < 0.001). Among individual score components, empiric echinocandin therapy and central venous catheter removal correlated with better outcomes. Centers with routine infectious disease (ID) consultations showed higher survival and adherence, reinforcing the value of specialist involvement. These findings support local epidemiological and management practice surveillance program adoption to address context-specific gaps, promote the adoption of best practices in <i>Candida</i> BSI management-as expanded ID specialist consultations and education programs-and, ultimately, reduce candidemia-related mortality rates.</p>","PeriodicalId":15878,"journal":{"name":"Journal of Fungi","volume":"11 5","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12113541/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144150610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>Act1</i> out of Action: Identifying Reliable Reference Genes in <i>Trichoderma reesei</i> for Gene Expression Analysis.","authors":"Caroline Danner, Yuriy Karpenko, Robert L Mach, Astrid R Mach-Aigner","doi":"10.3390/jof11050396","DOIUrl":"10.3390/jof11050396","url":null,"abstract":"<p><p><i>Trichoderma reesei</i> is a well-established industrial enzyme producer and has been the subject of extensive research for various applications. The basis of many research studies is the analysis of gene expression, specifically with RT-qPCR, which requires stable reference genes for normalization to yield reliable results. Yet the commonly used reference genes, <i>act1</i> and <i>sar1</i>, were initially chosen based on reports from the literature rather than systematic validation, raising concerns about their stability. Thus, properly evaluated reference genes for <i>T. reesei</i> are lacking. In this study, five potentially new reference genes were identified by analyzing publicly available transcriptome datasets of the <i>T. reesei</i> strains QM6a and Rut-C30. Their expression stability was then evaluated under relevant cultivation conditions using RT-qPCR and analyzed with RefFinder. The two most stable candidate reference genes were further validated by normalizing the expression of the well-characterized gene <i>cbh1</i> and comparing the results to those obtained using <i>act1</i> and <i>sar1</i>. Additionally, <i>act1</i> and <i>sar1</i> were normalized against the new reference genes to assess the variability in their expression. All five new reference genes exhibited a more stable expression than <i>act1</i> and <i>sar1</i>. Both in silico and RT-qPCR analysis ranked the so far uncharacterized gene, <i>bzp1</i>, as the most stable. Further, we found that <i>act1</i> and <i>sar1</i> have strain- and condition-dependent expression variability, suggesting that they are unsuitable as universal reference genes in <i>T. reesei</i>. Based on these results, we propose to use the combination of <i>bzp1</i> and <i>tpc1</i> for the normalization in RT-qPCR analysis instead of <i>act1</i> and <i>sar1</i>.</p>","PeriodicalId":15878,"journal":{"name":"Journal of Fungi","volume":"11 5","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12112898/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144150716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Whole-Genome Sequencing and Comparative Genomic Analysis of Three Clinical Bloodstream Infection Isolates of <i>Trichosporon austroamericanum</i>.","authors":"Takanori Horiguchi, Takashi Umeyama, Hiroko Tomuro, Amato Otani, Takayuki Shinohara, Masahiro Abe, Shogo Takatsuka, Ken Miyazawa, Minoru Nagi, Yasunori Muraosa, Yasutaka Hoshino, Takashi Sakoh, Hideki Araoka, Naoyuki Uchida, Tomoyoshi Kaneko, Yuko Nagano, Hiroki Tsukada, Taiga Miyazaki, Yoshitsugu Miyazaki","doi":"10.3390/jof11050401","DOIUrl":"10.3390/jof11050401","url":null,"abstract":"<p><p><i>Trichosporon austroamericanum</i> is a recently described yeast species related to <i>Trichosporon inkin</i> and exclusively isolated from clinical specimens. However, its genomic features and pathogenic potential remain poorly understood. In this study, we performed whole-genome sequencing on three blood-derived isolates from patients with invasive fungal infections and comparative analyses with 13 related <i>Trichosporon</i> species. The three isolates yielded high-quality assemblies of 9-10 scaffolds (~21 Mb), facilitating reliable comparisons. While most species had comparable genome sizes, <i>Trichosporon ovoides</i>, <i>Trichosporon coremiiforme</i>, and <i>Cutaneotrichosporon mucoides</i> displayed large, fragmented genomes, suggestive of polyploidy. ANI analysis and phylogenetic trees based on ANI and single-copy orthologs supported the classification of <i>T. austroamericanum</i> as a distinct clade with moderate intraspecific divergence. Using the <i>Galleria mellonella</i>, a model for fungal pathogenicity, all <i>T. austroamericanum</i> strains reduced larval survival, and NIIDF 0077300 exhibited virulence comparable to <i>T. asahii</i> and greater than <i>T. inkin</i>. To explore the gene-level differences associated with pathogenicity, we performed ortholog analysis based on single-copy genes. This revealed a unique Zn(II)₂Cys₆-type transcription factor gene (OG0010545) present only in NIIDF 0077300 and <i>T. asahii</i>. These findings highlight the genomic diversity and infection-associated traits of <i>T. austroamericanum</i>, providing a framework for future functional studies.</p>","PeriodicalId":15878,"journal":{"name":"Journal of Fungi","volume":"11 5","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12113199/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144150730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"FGSE02, a Novel Secreted Protein in <i>Fusarium graminearum</i> FG-12, Leads to Cell Death in Plant Tissues and Modulates Fungal Virulence.","authors":"Zhigang Hao, Lei Pan, Jiaqing Xu, Chengxuan Yu, Jianqiang Li, Laixin Luo","doi":"10.3390/jof11050397","DOIUrl":"10.3390/jof11050397","url":null,"abstract":"<p><p>Fungal phytopathogens employ effector proteins and secondary metabolites to subvert host immunity. Effector proteins have attracted widespread interest in infection, especially for unknown, unreported genes. However, the type of protein remains much less explored. Here, we combined transcriptome analysis and functional validation to identify virulence-associated genes in <i>Fusarium graminearum</i> during fungi infection. A unique secreted protein, FGSE02, was significantly upregulated in the early infection stage. Proteomic characterization revealed that the protein contains a functional signal peptide but lacks known domains. The transient expression of FGSE02 in <i>Nicotiana benthamiana</i> induced rapid cell death, while gene knockout stains reduced fungal virulence without affecting growth. Our findings highlight FGSE02 as a key virulence factor, offering potential targets for disease control. Taken together, the results of this study identify a pathogenic factor and provide new insights into the development of green pesticides.</p>","PeriodicalId":15878,"journal":{"name":"Journal of Fungi","volume":"11 5","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12113282/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144150615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Myricetin Exerts Antibiofilm Effects on <i>Candida albicans</i> by Targeting the RAS1/cAMP/EFG1 Pathway and Disruption of the Hyphal Network.","authors":"Melda Meral Ocal, Merve Aydin, Esra Sumlu, Emine Nedime Korucu, Ali Ozturk","doi":"10.3390/jof11050398","DOIUrl":"10.3390/jof11050398","url":null,"abstract":"<p><p>Increasing antifungal resistance and side effects of existing drugs demand alternative approaches for treating <i>Candida</i> (<i>C.</i>) infections. This study aimed to comprehensively evaluate the antifungal efficacy of myricetin (MYR), a natural flavonoid, against both fluconazole (FLC)-resistant and susceptible clinical <i>Candida</i> strains, with a particular focus on its inhibitory effects on <i>C. albicans</i> biofilms. Antifungal susceptibility was evaluated on <i>Candida</i> spp. by the broth microdilution method, and the impact of myricetin on <i>C. albicans</i> biofilms was determined using the Cell Counting Kit-8 (CCK-8) assay. To understand the molecular mechanisms underlying the antibiofilm properties of myricetin, expression analysis of genes in the RAS1/cAMP/EFG1 pathway (<i>ALS3</i>, <i>HWP1</i>, <i>ECE1, UME6</i>, <i>HGC1</i>) and cAMP-dependent protein kinase regulation (<i>RAS1, CYR1, EFG1</i>) involved in the transition from yeast to hyphae was performed. Field emission scanning electron microscopy (FESEM) was used to study the ultrastructural changes and morphological dynamics of <i>Candida</i> biofilms after exposure to MYR and FLC. The in vivo toxicity of myricetin was evaluated by survival analysis using the <i>Galleria mellonella</i> model. Myricetin significantly suppressed key genes related to hyphae development (<i>RAS1</i>, <i>CYR1</i>, <i>EFG1</i>, <i>UME6</i>, and <i>HGC1</i>) and adhesion (<i>ALS3</i> and <i>HWP1</i>) in both clinical and reference <i>Candida</i> strains at a concentration of 640 µg/mL. FESEM analysis revealed that myricetin inhibited hyphae growth and elongation in <i>C. albicans</i>. This study highlights the promising antibiofilm potential of myricetin through a significant inhibition of biofilm formation and hyphal morphogenesis.</p>","PeriodicalId":15878,"journal":{"name":"Journal of Fungi","volume":"11 5","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12113504/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144150821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phenotypic and Molecular Characterization of Multidrug-Resistant Clinical Isolates of the <i>Candidozyma haemuli</i> Species Complex (Formerly <i>Candida haemulonii</i> Species Complex) from the Brazilian Amazon Reveals the First Case of <i>Candidozyma pseudohaemuli</i> in Brazil.","authors":"Sérgio Lobato França, Rodrigo Santos de Oliveira, Gabriel Silas Marinho Sousa, Sarah Rodrigues de Sá, Walber da Silva Nogueira, Elaine Patrícia Tavares do Espírito Santo, Daniel Dos Santos Caldas, Silvia Helena Marques da Silva","doi":"10.3390/jof11050394","DOIUrl":"10.3390/jof11050394","url":null,"abstract":"<p><p>This study included 24 isolates of the <i>Candidozyma haemuli</i> species complex from patients in the Brazilian Amazon between 2021 and 2024. These isolates were identified by sequencing as <i>C. duobushaemuli</i> (54.2%), <i>C. haemuli</i> sensu stricto (29.2%), <i>C. haemuli</i> var. <i>vulneris</i> (12.5%), and <i>C. pseudohaemuli</i> (4.2%). The finding of <i>C. pseudohaemuli</i> represents the first case reported in Brazil. Haplotype and phylogenetic analysis of these species, along with other isolates from Brazil, revealed low intraspecific genetic diversity. Resistance to at least one antifungal was observed in 83.3% of isolates, with multidrug resistance in 58.3%, including one isolate resistant to all tested antifungals. The isolates demonstrated active biofilm production, lytic enzyme activity, and thermotolerance. Notably, one <i>C. duobushaemuli</i> isolate exhibited tolerance to 42 °C, a phenotype not previously described. It is crucial for Brazil and other countries to recognize the emergence of these species as a public health threat and to take proactive measures to prevent outbreaks.</p>","PeriodicalId":15878,"journal":{"name":"Journal of Fungi","volume":"11 5","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12113443/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144150216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pine Forest Plantations in the Neotropics: Challenges and Potential Use of Ectomycorrhizal Fungi and Bacteria as Inoculants.","authors":"Yajaira Baeza-Guzmán, Sara Lucía Camargo-Ricalde, Dora Trejo-Aguilar, Noé Manuel Montaño","doi":"10.3390/jof11050393","DOIUrl":"10.3390/jof11050393","url":null,"abstract":"<p><p>Forest plantations in the Neotropics aim to alleviate pressure on primary forests. This study synthesizes knowledge on pine species used in these plantations, emphasizing the challenges and potential of ectomycorrhizal fungi and bacteria as inoculants. An analysis of 98 articles identifies 23 pine species in Mexico and Central America and about 16 fast-growing species in South America. While pine plantations provide a habitat for generalist species, they reduce the richness of specialist species. Ectomycorrhizal fungi and bacterial diversity in plantations with introduced pines is up to 20% lower compared to native ecosystems. <i>Suillus</i> and <i>Hebeloma</i> are commonly used as mycorrhizal inoculants for Neotropical and introduced species, including <i>Pinus ponderosa</i> and <i>Pinus radiata</i> in South America. Commercial inoculants predominantly feature the fungal species <i>Pisolithus tinctorius</i>, alongside bacterial genera such as <i>Bacillus</i>, <i>Cohnella</i>, and <i>Pseudomonas</i>. This study emphasizes the importance of leveraging native microbial communities and their synergistic interactions with ECM fungi and bacteria to enhance seedling growth and quality. Such a combined approach can improve plantation survival, boost resilience to environmental stressors, and promote long-term productivity. These findings underscore the need to incorporate native fungi and bacteria into inoculant strategies, advancing sustainable forestry practices and ecosystem adaptation in the Neotropics.</p>","PeriodicalId":15878,"journal":{"name":"Journal of Fungi","volume":"11 5","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12113481/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144150223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genomic Sequencing and Characterization of Two <i>Auricularia</i> Species from the Qinling Region: Insights into Evolutionary Dynamics and Secondary Metabolite Potential.","authors":"Jianzhao Qi, Shijie Kang, Ming Zhang, Shen Qi, Yulai Li, Khassanov Vadim, Shuangtian Du, Minglei Li","doi":"10.3390/jof11050395","DOIUrl":"10.3390/jof11050395","url":null,"abstract":"<p><p><i>Auricularia</i> mushrooms, common bulk edible fungi, have considerable culinary and medicinal value. The Qinling region, represented by Zhashui County, is the main production area of <i>Auricularia</i> mushrooms in China. In this study, two wild <i>Auricularia</i> strains, M12 and M13, selected from the Qinling region for their desirable horticultural traits after domestication, were sequenced and characterized. Sequencing assembly results based on Illumina NovaSeq and PacBio Sequel II HiFi showed that the M12 genome was 56.04 Mbp in size, with 2.58% heterozygosity and 14.13% repetitive sequences, and was anchored on 12 chromosomes using HI-C technology. In contrast, the M13 genome was 52.10 Mbp, showed 2.34% heterozygosity, 13.89% repetitive sequences, and was assembled into 12 scaffolds. Collinearity analysis revealed extensive homologous regions between the M12 and M13 genomes. Phylogenetic analysis suggested that the divergence between M12 and M13 occurred approximately 4.575 million years ago (MYAs), while their divergence from <i>Auricularia subglabra</i> TFB-10046 SS5 occurred approximately 33.537 MYAs. Analyses of CYP450, carbohydrate-active enzymes (CAZymes), and gene family expansion/contraction revealed distinct genomic features between the two strains. SSR and LTR insertion time analyses revealed the genome dynamics of the two strains during their evolution. Analysis of secondary metabolite-associated biosynthetic gene clusters (BGCs) provides powerful clues to understand the origin of bioactive compounds in the <i>Auricularia</i> mushroom. This work represents the first genome sequencing of the <i>Auricularia</i> species derived from the Qinling region. These results not only enriched our understanding of the <i>Auricularia</i> genome but also provided an important genomic resource and theoretical basis for the subsequent genetic breeding, functional gene mining, and development of medicinal components of <i>Auricularia</i> species.</p>","PeriodicalId":15878,"journal":{"name":"Journal of Fungi","volume":"11 5","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12113221/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144150717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}