Journal of Prevention, Diagnosis and Management of Human Diseases最新文献

{"title":"Blood Sugar Concentration, HbA1C, and Lipid Profile in Heart Patients","authors":"R. H. Alwan","doi":"10.55529/jpdmhd.43.18.26","DOIUrl":"https://doi.org/10.55529/jpdmhd.43.18.26","url":null,"abstract":"The study included 45 samples (30 patients with heart disease and have diabetes and 15 patients with Type 2 DM), their age between (40-60) years for both gender. Samples were collected from Kirkuk general hospital from April 2023 to September 2023. The individuals of this study were divided into two groups: The first group was for patients with heart disease n (30), and the second group for individual have diabetes only n (15). Result: Heart disease patients had higher mean serum cholesterol, triglyceride, LDL, and VLDL levels (225.1±25.2, 209.5±8.3, 140.7±17.9, 41.9±4.61) compared to diabetes patients (196.3±27.2, 165±6.1, 119.67±15.2, 33.00±3.22) at a P-value < 0.05. HDL levels were similar across groups at P > 0.05. The research demonstrates the mean FBS and HbA1C of 30 heart disease and 15 diabetic patients. The study found that heart disease patients had higher mean serum FBS and HbA1C levels (282.8±36.41 mg/dl, 10.35±3.18%) compared to diabetes patients (175.2±32.79 mg/dl, 8.22±2.51%). A P-value < 0.05. Conclusion: The study concluded appositive association between dyslipidemia and heart disease in which increased cholesterol, triglyceride, low-density lipoprotein (LDL), very-low-density lipoprotein (VLDL), fasting blood glucose and HbA1C and no differences between heart disease and diabetes patients.","PeriodicalId":156613,"journal":{"name":"Journal of Prevention, Diagnosis and Management of Human Diseases","volume":"285 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140749917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Some Biometrics and Biochemical Parameters in Migraine Patients","authors":"Faiz Ali Al-Mfrgi, M. Salih","doi":"10.55529/jpdmhd.43.9.17","DOIUrl":"https://doi.org/10.55529/jpdmhd.43.9.17","url":null,"abstract":"Background: Migraine is a pulsating and recurrent headache in one or both side. It may be caused by induce of nerves in the brain blood vessels walls and its associates with photophobia. Objectives: Measure of Body mass index (BMI), blood pressure (BP), serum calcium (Ca), magnesium (Mg) and iron (Fe) in migraine patients. Methods: This study performed on 94 persons (64 migraine: 30 control), who visited Al-Duloya General Hospital, Tikrit Educational Hospital, and neurological clinics in Al-Duloya and Tkrit. Also it contains visiting participants to their homes in Salahaddin in Iraq. A socio-demographic characters, length, weight, and BP taken directly. 3-5ml blood sampled for obtaining serum. Biochemical tests analyzed by spectrophotometer in Central laboratory of Tikrit University. The study period extended from 30-7-2023 to 27-9-2023. GraphPrism9 program and T-test used for statistical analysis. Results: Patient age was 34.9(16-63) year. Higher percentages reported in female (79.6%) and family history (68.7%). BMI (29.1±5.5), (27.6±5.3) kg/m2, systolic BP (11.7±1.2), (11.5±1.1), and diastolic BP (7.5±0.8), (7.2±1.0) Cm.Hg, show non-significant elevation in migraine compare with control respectively. Mg reveals significant decrease (1.7±0.7), (2.1±0.6), but Ca (7±0.5), (7.3±0.7) and Iron (82±57), (90±52) mg/dL reveal non-significant decrease in migraine compare with control respectively. Conclusions: BMI and BP show non-significant elevation. While Mg reveals significant decrease, Ca and Iron reveal non-significant decrease in patients.","PeriodicalId":156613,"journal":{"name":"Journal of Prevention, Diagnosis and Management of Human Diseases","volume":"363 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140788298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Some Biochemical Variables among Smoker Athletes in Kirkuk City","authors":"Essa Omran JassimSayran Sattar Saleh, S. Saleh","doi":"10.55529/jpdmhd.43.1.8","DOIUrl":"https://doi.org/10.55529/jpdmhd.43.1.8","url":null,"abstract":"The study aimed to evaluate the levels of some biochemical variables such as vitamins C, E, and D, as well as albumin and uric acid levels, in addition to levels of fatty proteins in the blood serum of a group of smoking athletes and compare the results with the levels of these biochemical variables in non-smoking athletes (as a control group). The study sample included 100 individuals divided into two groups: smoking athletes (60 individuals) and non-smoking athletes (40 individuals), in addition to calculating the Body Mass Index (BMI).The study results showed lower levels of vitamins C and E in smokers athletes compared to non-smokers athletes, while vitamin D levels were low in both smokers and non-smokers athletes. The results also showed a decrease in albumin and uric acid levels in smokers’ athletes. Additionally, levels of fatty proteins (T.G, Cholesterol, HDL, LDL, VLDL) were measured, and the levels were within the normal range for both smokers and non-smokers athletes.","PeriodicalId":156613,"journal":{"name":"Journal of Prevention, Diagnosis and Management of Human Diseases","volume":"409 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140787962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long Non-Coding RNAs in Kidney Injury: A Comprehensive Review","authors":"Ramdas Bhat, Preeti Shanbhag","doi":"10.55529/jpdmhd.42.39.52","DOIUrl":"https://doi.org/10.55529/jpdmhd.42.39.52","url":null,"abstract":"Kidney injury, a global health challenge, necessitates a nuanced understanding of molecular intricacies for effective interventions. Long non-coding RNAs (lncRNAs), once dismissed as transcriptional noise, now emerge as pivotal players in orchestrating renal health. Dysregulation of specific lncRNAs like TUG1, MALAT1, H19, and NEAT1 provides molecular signatures, distinguishing physiological states from pathological conditions. In acute kidney injury (AKI), TUG1 and MALAT1 regulate apoptosis, inflammation, and fibrosis. Chronic kidney disease (CKD) involves lncRNAs like H19 and NEAT1 modulating cell proliferation and apoptosis. Beyond diagnostics, lncRNAs actively shape inflammation, apoptosis, and fibrosis, positioning them as master regulators in the intricate ballet of kidney health. Recent strides in research, coupled with cutting-edge genomics and bioinformatics tools, highlight their roles and therapeutic potential. Challenges in understanding their intricate roles and interactions necessitate the exploration of promising avenues, including single-cell RNA sequencing and artificial intelligence, paving the way for personalized interventions and regenerative medicine in kidney diseases.","PeriodicalId":156613,"journal":{"name":"Journal of Prevention, Diagnosis and Management of Human Diseases","volume":"133 S229","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140256662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Using Speckle Tracking Analysis, Does Age Affect RV Longitudinal Strain?","authors":"Elham H. Manhal Al. Obaidi, Asaad Hasan Noaman Al-Aboodi","doi":"10.55529/jpdmhd.42.29.38","DOIUrl":"https://doi.org/10.55529/jpdmhd.42.29.38","url":null,"abstract":"Introduction: The right ventricle (RV) is increasingly crucial in clinical settings, but traditional echocardiography is challenging to evaluate its function. Advanced techniques like speckle tracking improve RV functional assessment. According to previous studies, RV free wall longitudinal strain measurements vary with age necessitating further research. Aim: This study aimed to evaluate the effects of age on RV longitudinal strain using speckle tracking (ST) analysis. Methods: 103 healthy adult volunteers, mean age 37.1±11.9 years (range: 20-66), underwent comprehensive speckle tracking analysis, to determine age-related changes in RV dimensions and function. Results: showed a significant decrease in global and segmental (basal, mid, and apical) FWLS with age (p < .001). Conclusion: These significant differences in free wall longitudinal strains among age groups by 2D-ST analysis indicate the need for age-adjusted measures in RV function evaluation. Conventional techniques may ignore minor changes, leading to underestimated RV function assessment. The findings also suggest that advanced techniques allow early identification of RV dysfunction by detecting subclinical dysfunction before anomalies revealed by traditional echocardiography occur.","PeriodicalId":156613,"journal":{"name":"Journal of Prevention, Diagnosis and Management of Human Diseases","volume":"136 25","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140423310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation between Serum Levels of Progranulin and Spirometric Readings in Patients with Chronic Obstructive Pulmonary Disease","authors":"Fatima Ali Alkyoon, Falah Mahdi Dananah","doi":"10.55529/jpdmhd.42.21.28","DOIUrl":"https://doi.org/10.55529/jpdmhd.42.21.28","url":null,"abstract":"Back ground Chronic Obstructive Pulmonary Disease (COPD) is a chronic Inflammatory disease of the airways and/ or parenchyma usually characterized by progressive irreversible airflow with accompanying respiratory symptoms like dyspnea, cough, production of sputum, and/or exacerbations. The pathophysiology Of COPD involves bronchitis and /or emphysema, the effect of inflammation occurs in the lung and also have systemic effect, most common causes is tobacco smoking, occupational pollution, indoor pollution. Progranulin ( PGRN ) is defined as precursor of pleiotropic glycosylated protein ,it have significant role in process of inflammation ,angiogenesis, neoplasia ,cell development ,cell cycle , embryogenesis, wound healing ,modification of autoimmune process, highly found in several type of cells like respiratory epithelial cells.\u0000Objective: The aim is to study relationship between serum level of PGRN and spirometric readings in COPD patients.\u0000Patients and method: A case control study composed of 40 patients with COPD and 45 controls, demographic characteristic, pulmonary function test and plasma PGRN were measured and made comparison of data in cases with controls, data collected were statically analysis by SPSS.\u0000Result: This study found that serum PGRN was elevated in cases of COPD more than controls (230.52±189.01 VS 114.19±68.41 ng/ml) there is significant association between PGRN and COPD ( P value 0.006 ) ,and found that PGRN negatively associated with FEV1 % ( P value 0.04 )\u0000Conclusions: It was concluded that PGRN may be used as blood marker that indicate severity of airflow obstruction in COPD.","PeriodicalId":156613,"journal":{"name":"Journal of Prevention, Diagnosis and Management of Human Diseases","volume":"57 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140419787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of Proprioceptive Neuromuscular Facilitation Technique on Balance and Mobility in Chronic Stroke Patient","authors":"Shreyash A. Manapure","doi":"10.55529/jpdmhd.42.9.20","DOIUrl":"https://doi.org/10.55529/jpdmhd.42.9.20","url":null,"abstract":"This comprehensive review explores the multifaceted impact of stroke, a cerebrovascular disorder, on individuals, emphasizing the physical, emotional, and cognitive dimensions of its aftermath. Stroke is a major global health concern, contributing significantly to mortality and disability. The immediate consequences involve neurological impairments such as paralysis, speech difficulties, and impaired vision, while the emotional toll includes coping with loss and adjusting to new realities. Long-term cognitive implications affect memory, attention, and executive function, adding complexity to the recovery journey. Communication challenges, physical limitations, and the risk of secondary complications are discussed, highlighting the importance of a continuum of care. The role of caregivers is explored, emphasizing the emotional, physical, and financial burdens they face. Technological innovations, such as virtual reality and robotics, are introduced as promising tools in stroke rehabilitation. The focus then shifts to balance and mobility issues in stroke survivors, particularly the impact of proprioceptive neuromuscular facilitation (PNF) techniques. Proprioceptive neuromuscular facilitation emerges as a dynamic and versatile therapeutic approach, offering promise for improved functional outcomes and enhanced quality of life in the evolving landscape of stroke care and rehabilitation. The review delves into the neurophysiological ballet of PNF, emphasizing neuromuscular stimulation, neuroplasticity, and motor learning. Clinical applications of PNF in orthopaedic, neurological, geriatric, and paediatric rehabilitation are discussed, highlighting its versatility.","PeriodicalId":156613,"journal":{"name":"Journal of Prevention, Diagnosis and Management of Human Diseases","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140437285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Relationship between the Prevalence of Cesarean Sections and Progesterone (Duphaston) Usage during Pregnancy","authors":"","doi":"10.55529/jpdmhd.42.1.8","DOIUrl":"https://doi.org/10.55529/jpdmhd.42.1.8","url":null,"abstract":"Background: Progesterone plays a crucial part in ovulation, implantation, and pregnancy, among other reproductive processes.This is related to progesterone's role in controlling cyclical changes in decidualization and proliferation, which regulate uterine function during the menstrual cycle. Progesterone is necessary for the development of decidual tissues. In the event of fertilization, high levels of progesterone in the blood are crucial for maintaining pregnancy by promoting uterine growth and inhibiting the effects of factors that cause myometrial contraction. During a cesarean section, the fetus is delivered via a surgical incision made in the woman's abdomen (laparotomy) and in her uterus (hysterotomy). The likelihood of experiencing health issues following a cesarean birth is somewhat increased due to the high number of caesarean sections performed globally in comparison to spontaneous births. Method: 65 pregnant women participated in this cross-sectional study, which ran from October 1, 2022, to March 20, 2023, in the gynecological department of Salah Al Deen General Hospital in the Salah al Deen governorate and in Diyala. Result: As in result of questioners in pregnancies take the progesterone as stabilizer About 75.4% of participants were delivered by cesarean section and only 24.6% were delivered by normal vaginal delivery . Conclusion: The regular use of progestagens for the treatment of impending miscarriage may have contributed to the increased rate of cesarean sections among the participants.","PeriodicalId":156613,"journal":{"name":"Journal of Prevention, Diagnosis and Management of Human Diseases","volume":"23 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140440361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Musculoskeletal Pain and Related Factors among Foreign Medical Students of Bishkek, Kyrgyzstan: A Cross-Sectional Study","authors":"Dr. Muhammad Imamuzzaman, Dr. Sulaimanov Baktyar Janyshovich, Dr. Kanij Ftaema Mukta, Dr. Sumit Mishra","doi":"10.55529/jpdmhd.41.31.39","DOIUrl":"https://doi.org/10.55529/jpdmhd.41.31.39","url":null,"abstract":"Musculoskeletal pain impacts our daily lives in numerous ways. So, it is very important to investigate this problem to find out its prevalence and factors related to it. \u0000Methods: A descriptive cross-sectional study was carried out among 360 randomly selected medical students from different medical colleges in Bishkek, Kyrgyzstan. With consent, data was collected by the principal investigator by pretested interview schedule through face-to-face interviews. Participants had the freedom to withdraw from the study at any point without the obligation to provide a reason, and measures were taken to maintain data confidentiality. The procedure posed no physical, mental, or social risks. Data were analysed by SPSS version 25.0 and presented through tables and diagrams for clarity.\u0000Results: Of the respondents, 213(59.2%) had musculoskeletal pain. But the majority 314(87.2%) had no history of trauma and 221(61.4%) had a family history of musculoskeletal pain. Of them, only 116(32.2%) respondents performed physical exercise while nearly two-thirds 224(62.2%) had normal BMI. Near cent per cent of respondents had prolonged sitting history, which is more than 2 hours. Most 273(75.8%) of them use chairs for study purposes. Near three-fourths, 259(71.9%) had travel time of more than one hour per day and a significant 328(91.1%) number of them use backpacks. Of 213 sufferers, more than two-fifths 128(60.1%) had musculoskeletal pain often. Almost half (47.4%) of medical students were suffering from back pain and 69(32.4%) from neck pain.\u0000Conclusion: Medical students were suffering from musculoskeletal pain with no history of trauma and positive family history. Students do not perform physical exercise regularly with normal BMI. During travel, they use backpacks to carry educational materials. Smartphones, computers or laptops are used by them during their leisure time. Students were mainly suffering from back, neck and shoulder pain.","PeriodicalId":156613,"journal":{"name":"Journal of Prevention, Diagnosis and Management of Human Diseases","volume":"422 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140471152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Adropin Levels in Cardiovascular Disease","authors":"Mutlak M. Taha, S. N. Muhsen","doi":"10.55529/jpdmhd.41.22.30","DOIUrl":"https://doi.org/10.55529/jpdmhd.41.22.30","url":null,"abstract":"Biomarker studies for the diagnosis of myocardial infarction are continuing. Adropin is a biomarker that has been researched and found to have various effects. The purpose of this study was to look at the adropin levels of patients who had a myocardial infarction and angina pectoris.\u0000Material and Methods: The control group comprised 30 individuals whose troponin levels did not rise and no coronary lesions were found. In the myocardial infarction group, 30 patients had an elevated ECG, and 30 patients had angina pectoris. They were diagnosed by clinicians and tested for Adropin, Fetuin-A, Selenoprotein-P, MDA, and Copeptin.\u0000Results: In the MI group, a significant increase was observed in the adropin level p < 0.01**. While a strong positive correlation existed between Fetuin-A and adropin (r= 0.82, p< 0.001) as well as between selenoprotein-P and adropin (r= 0.64, p< 0.001)","PeriodicalId":156613,"journal":{"name":"Journal of Prevention, Diagnosis and Management of Human Diseases","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140477447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}