Journal of electrocardiology最新文献

{"title":"Clinical usability of deep learning-based saliency maps for occlusion myocardial infarction identification from the prehospital 12-Lead electrocardiogram","authors":"Nathan T. Riek PhD(c) ,&nbsp;Tanmay A. Gokhale MD, PhD ,&nbsp;Christian Martin-Gill MD, MPH ,&nbsp;Karina Kraevsky-Philips PhD(c), RN ,&nbsp;Jessica K. Zègre-Hemsey RN, PhD ,&nbsp;Samir Saba MD ,&nbsp;Clifton W. Callaway MD, PhD ,&nbsp;Murat Akcakaya PhD ,&nbsp;Salah S. Al-Zaiti PhD","doi":"10.1016/j.jelectrocard.2024.153792","DOIUrl":"10.1016/j.jelectrocard.2024.153792","url":null,"abstract":"<div><h3>Introduction</h3><p>Deep learning (DL) models offer improved performance in electrocardiogram (ECG)-based classification over rule-based methods. However, for widespread adoption by clinicians, explainability methods, like saliency maps, are essential.</p></div><div><h3>Methods</h3><p>On a subset of 100 ECGs from patients with chest pain, we generated saliency maps using a previously validated convolutional neural network for occlusion myocardial infarction (OMI) classification. Three clinicians reviewed ECG-saliency map dyads, first assessing the likelihood of OMI from standard ECGs and then evaluating clinical relevance and helpfulness of the saliency maps, as well as their confidence in the model's predictions. Questions were answered on a Likert scale ranging from +3 (most useful/relevant) to −3 (least useful/relevant).</p></div><div><h3>Results</h3><p>The adjudicated accuracy of the three clinicians matched the DL model when considering area under the receiver operating characteristics curve (AUC) and F1 score (AUC 0.855 vs. 0.872, F1 score = 0.789 vs. 0.747). On average, clinicians found saliency maps slightly clinically relevant (0.96 ± 0.92) and slightly helpful (0.66 ± 0.98) in identifying or ruling out OMI but had higher confidence in the model's predictions (1.71 ± 0.56). Clinicians noted that leads I and aVL were often emphasized, even when obvious ST changes were present in other leads.</p></div><div><h3>Conclusion</h3><p>In this clinical usability study, clinicians deemed saliency maps somewhat helpful in enhancing explainability of DL-based ECG models. The spatial convolutional layers across the 12 leads in these models appear to contribute to the discrepancy between ECG segments considered most relevant by clinicians and segments that drove DL model predictions.</p></div>","PeriodicalId":15606,"journal":{"name":"Journal of electrocardiology","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0022073624002620/pdfft?md5=35679429fcb9a91950afb59c5b50379d&pid=1-s2.0-S0022073624002620-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142157850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A novel way to prospectively evaluate of AI-enhanced ECG algorithms","authors":"","doi":"10.1016/j.jelectrocard.2024.06.046","DOIUrl":"10.1016/j.jelectrocard.2024.06.046","url":null,"abstract":"<div><p><span><span>Significant strides will be made in the field of computerized electrocardiology through the development of artificial intelligence (AI)-enhanced ECG (AI-ECG) algorithms. Yet, the scientific discourse has primarily relied upon on retrospective analyses for deriving and externally validating AI-ECG classification algorithms, an approach that fails to fully judge their real-world effectiveness or reveal potential unintended consequences. Prospective trials and analyses of AI-ECG algorithms will be crucial for assessing real-world diagnostic scenarios and understanding their practical utility and degree influence they confer onto clinicians. However, conducting such studies is challenging due to their resource-intensive nature and associated technical and logistical hurdles. To overcome these challenges, we propose an innovative approach to assess AI-ECG algorithms using a virtual testing environment. This strategy can yield critical insights into the practical utility and clinical implications of novel AI-ECG algorithms. Moreover, such an approach can enable an assessment of the influence of AI-ECG algorithms have their users. Herein, we outline a proposed </span>randomized control trial for evaluating the diagnostic efficacy of new AI-ECG algorithm(s) specifically designed to differentiate between </span>wide complex tachycardias<span> into ventricular tachycardia and supraventricular wide complex tachycardia.</span></p></div>","PeriodicalId":15606,"journal":{"name":"Journal of electrocardiology","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141600177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can the efficacy of a medical treatment be predicted based on the type of idiopathic premature ventricular contraction?","authors":"Adem Atici M.D. ,&nbsp;Irfan Sahin M.D. ,&nbsp;Ömer Doğan M.D. ,&nbsp;Hasan Ali Barman M.D. ,&nbsp;Ayhan Kup M.D. ,&nbsp;Mehmet Celik M.D. ,&nbsp;Ahmet Demirkiran M.D. ,&nbsp;Yusuf Yilmaz M.D. ,&nbsp;Fatma Betul Ozcan M.D. ,&nbsp;Erdem Cevik M.D. ,&nbsp;Hüseyin Orta M.D. ,&nbsp;Mustafa Yılmaz M.D. ,&nbsp;Ali Ugur Soysal M.D. ,&nbsp;Mehmet Tugay Yumuk M.D. ,&nbsp;Sevil Tugrul Yavuz M.D. ,&nbsp;Fatih Öztürk M.D. ,&nbsp;Medeni Karaduman M.D. ,&nbsp;İshak Yilmaz M.D. ,&nbsp;Mustafa Caliskan","doi":"10.1016/j.jelectrocard.2024.153782","DOIUrl":"10.1016/j.jelectrocard.2024.153782","url":null,"abstract":"<div><h3>Background</h3><p>Premature ventricular contractions (PVCs) are common arrhythmias with diverse clinical implications. This retrospective study aimed to evaluate the efficacy of medical treatments using various clinical, imaging, and electrocardiographic parameters in patients with idiopathic PVCs.</p></div><div><h3>Methods</h3><p>A total of 1051 patients with idiopathic PVCs were retrospectively analyzed. Patients were categorized into three groups based on treatment response: beta-blocker (BB) responders (479 patients), calcium-channel blocker (CCB) responders (335 patients), and class 1c antiarrhythmic (AA) responders (237 patients). Clinical, imaging, and electrocardiographic data were collected and analyzed to assess the factors influencing treatment response.</p></div><div><h3>Results</h3><p>Age, left ventricular ejection fraction (LVEF), PVC QRS duration, CI variability, and multiple PVC morphologies were identified as significant factors affecting treatment response. Older age and lower LVEF were associated with better response to BB treatment, whereas CCB responders showed narrower QRS complexes. BB responders also exhibited higher CI variability, possibly linked to automaticity mechanisms. Moreover, the BB responder group had a higher frequency of multiple PVC morphologies.</p></div><div><h3>Conclusion</h3><p>These findings emphasize the importance of tailored treatment approaches based on individual patient characteristics.</p></div>","PeriodicalId":15606,"journal":{"name":"Journal of electrocardiology","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142097434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The assessment of adolescent obesity's effects on ventricular repolarization","authors":"","doi":"10.1016/j.jelectrocard.2024.06.045","DOIUrl":"10.1016/j.jelectrocard.2024.06.045","url":null,"abstract":"<div><h3>Background</h3><p>Currently, there is a lack of research on the Tp-Te interval and Tp-e/QT ratio in obese adolescents who have metabolic syndrome.</p></div><div><h3>Aim</h3><p>Our study aims to compare established ventricular repolarization<span><span> parameters with these intervals and ratios in obese adolescents with or without metabolic syndrome, alongside a healthy control group, while exploring the association of these </span>repolarization parameters with cardiovascular risk factors and echocardiographic variables.</span></p></div><div><h3>Methods</h3><p>The study included 100 obese adolescents and 50 lean subjects, with the obese participants categorized into two subgroups. The Tp-Te interval was identified as the duration from the peak to the end of the T wave.</p></div><div><h3>Results</h3><p>The metabolic and non-metabolic syndrome obese groups exhibited significantly elevated QTc and TpTe values compared to the control group, with no statistically significant differences observed in minimum QT, maximum QT, QT dispersion<span>, QTc dispersion, TpTe dispersion, and TpTe/QT ratio values among obese subjects with metabolic or non-metabolic syndrome and controls. Specifically, TpTe values were significantly elevated in the non-metabolic syndrome obese groups compared to controls, while minimum TpTe values were significantly elevated in the metabolic syndrome obese groups compared to controls, and the prolongation of the QTc interval was notably elevated in the obese groups than in controls.</span></p></div><div><h3>Conclusions</h3><p>Obese adolescents demonstrated an elevated TpTe interval compared to healthy controls, without any significant differences observed in TpTe dispersion, and TpTe/QT ratio values between the two groups. Results of our study showed that a negative correlation between TpTe and HDL-cholesterol and a positive correlation between the TpTe/QT ratio and insulin sensitivity indices in adolescents with metabolic syndrome.</p></div>","PeriodicalId":15606,"journal":{"name":"Journal of electrocardiology","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141600178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative analysis of parametric B-spline and Hermite cubic spline based methods for accurate ECG signal modeling","authors":"Alka Mishra,&nbsp;Surekha Bhusnur,&nbsp;Santosh Kumar Mishra,&nbsp;Pushpendra Singh","doi":"10.1016/j.jelectrocard.2024.153783","DOIUrl":"10.1016/j.jelectrocard.2024.153783","url":null,"abstract":"<div><p>Analyzing Electrocardiogram (ECG) signals is imperative for diagnosing cardiovascular diseases. However, evaluating ECG analysis techniques faces challenges due to noise and artifacts in actual signals. Machine learning for automatic diagnosis encounters data acquisition hurdles due to medical data privacy constraints. Addressing these issues, ECG modeling assumes a crucial role in biomedical and parametric spline-based methods have garnered significant attention for their ability to accurately represent the complex temporal dynamics of ECG signals. This study conducts a comparative analysis of two parametric spline-based methods—B-spline and Hermite cubic spline—for ECG modeling, aiming to identify the most effective approach for accurate and reliable ECG representation. The Hermite cubic spline serves as one of the most effective interpolation methods, while B-spline is an approximation method. The comparative analysis includes both qualitative and quantitative evaluations. Qualitative assessment involves visually inspecting the generated spline-based models, comparing their resemblance to the original ECG signals, and employing power spectrum analysis. Quantitative analysis incorporates metrics such as root mean square error (RMSE), Percentage Root Mean Square Difference (PRD) and cross correlation, offering a more objective measure of the model's performance. Preliminary results indicate promising capabilities for both spline-based methods in representing ECG signals. However, the analysis unveils specific strengths and weaknesses for each method. The B-spline method offers greater flexibility and smoothness, while the cubic spline method demonstrates superior waveform capturing abilities with the preservation of control points, a critical aspect in the medical field. Presented research provides valuable insights for researchers and practitioners in selecting the most appropriate method for their specific ECG modeling requirements. Adjustments to control points and parameterization enable the generation of diverse ECG waveforms, enhancing the versatility of this modeling technique. This approach has the potential to extend its utility to other medical signals, presenting a promising avenue for advancing biomedical research.</p></div>","PeriodicalId":15606,"journal":{"name":"Journal of electrocardiology","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142097524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Atypical Aslanger pattern in inferolateral myocardial infarction – A new variant to look out for?","authors":"Ashok Victor,&nbsp;Nageshwaran P.M.,&nbsp;Tamilselvan K.,&nbsp;Nihal Sheriff","doi":"10.1016/j.jelectrocard.2024.153786","DOIUrl":"10.1016/j.jelectrocard.2024.153786","url":null,"abstract":"<div><p>We report a case of a 53-year-old male with inferolateral myocardial infarction, presenting an atypical Aslanger pattern on electrocardiogram (ECG). The ECG showed ST elevation in leads III, aVR, aVF, and posterior leads, with ST depression in II and V2-V6 with terminal positive T waves. Coronary angiography revealed total occlusion of the left circumflex artery (LCx) with significant stenosis of the left anterior descending (LAD) and right coronary artery (RCA). The LCx was successfully revascularized. This case highlights the importance of recognizing atypical Aslanger patterns, which may indicate multivessel coronary artery disease.</p></div>","PeriodicalId":15606,"journal":{"name":"Journal of electrocardiology","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142150757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accelerated idioventricular rhythm after left bundle branch pacing lead implantation","authors":"Yoji Iida ,&nbsp;Junzo Inamura","doi":"10.1016/j.jelectrocard.2024.153788","DOIUrl":"10.1016/j.jelectrocard.2024.153788","url":null,"abstract":"<div><p>Premature ventricular contractions with right bundle branch block morphology induced during left bundle branch (LBB) pacing (LBBP) lead implantation serve as a marker indicating that the lead is close to or has reached the LBB region. However, no reports to date have described accelerated idioventricular rhythm (AIVR) induced by LBBP lead deployment.</p><p>We herein describe a patient who underwent LBBP for complete atrioventricular block. The patient's intrinsic escape rhythm was overtaken by AIVR induced immediately after LBBP lead deployment.</p><p>AIVR is another marker indicating that the lead has reached the LBB region.</p></div>","PeriodicalId":15606,"journal":{"name":"Journal of electrocardiology","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142145780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relevance of accurate QT correction in the assessment of long QT syndrome","authors":"Matias Kanniainen ,&nbsp;Teemu Pukkila ,&nbsp;Katriina Aalto-Setälä ,&nbsp;Esa Räsänen","doi":"10.1016/j.jelectrocard.2024.153790","DOIUrl":"10.1016/j.jelectrocard.2024.153790","url":null,"abstract":"<div><h3>Background</h3><p>Long QT syndrome (LQTS) is a genetic cardiac disease, where the corrected QT (QTc) interval is prolonged. It can cause arrhythmias and lead to a sudden cardiac death. Duration of the QT interval depends on the heart rate and this dependency is treated with QT correction. However, the current QT correction methods have well known problems and limitations.</p></div><div><h3>Objective</h3><p>We study the relevance of QT correction method in evaluating the risk of LQTS. We evaluate the reliability of the present and recently developed QT correction methods to discriminate LQTS subjects from healthy controls.</p></div><div><h3>Methods</h3><p>We use the clinically prevalent QT correction methods, particularly Bazett and Fridericia, in comparison with the recently developed AccuQT method. The data of healthy controls and LQTS subjects is extracted from the Rochester THEW database. The analysis accounts for sex, major LQTS subtypes, and beta-blocker treatment.</p></div><div><h3>Results</h3><p>QT values corrected with AccuQT discriminate the healthy and LQTS samples with the best accuracy, leading to (TP, TN) = (0.87, 0.65) with the conventional 450 ms threshold for LQTS. Fridericia correction yields lower sensitivity (0.71), but comparable balanced accuracy, whereas Bazett shows significantly less accurate results due to overcorrection at lower heart rates.</p></div><div><h3>Conclusion</h3><p>The selected QT correction method is important in the identification of LQTS. In particular, the use of Bazett correction should be questioned. Fridericia correction yields good results with respect to its simplicity. AccuQT has the best accuracy out of all the methods for LQTS discrimination. For practical applicability, however, AccuQT needs further validation in realistic clinical conditions.</p></div>","PeriodicalId":15606,"journal":{"name":"Journal of electrocardiology","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0022073624002607/pdfft?md5=9d58db9cf66077320d62f5c225845794&pid=1-s2.0-S0022073624002607-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142130183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genesis of ischemic ST segment changes: A study using precordial bipolar leads and regional vectorcardiograms","authors":"Mario J. Mc Loughlin MD","doi":"10.1016/j.jelectrocard.2024.153789","DOIUrl":"10.1016/j.jelectrocard.2024.153789","url":null,"abstract":"<div><h3>Background</h3><p>Precordial Bipolar Leads (PBLs), Weighted Unipolar Leads (WUL), and Regional Vectorcardiograms (RVCGs) are constructed using the same data recorded by a standard 12‑lead ECG, but they provide additional information not visible in the standard 12‑lead ECG (ECG) tracings.</p></div><div><h3>Objectives</h3><p>In previous studies during balloon occlusion of the LAD and RCA, we observed a complete ischemic inversion of the QRS waves, with folding of the loop and ST segment shift. In the present study, we aim to investigate this abnormality using new ECG methods. We hypothesize that utilizing PBL, WUL, and RVCG in patients with ischemia caused by total acute coronary artery occlusion enables the detection of specific abnormalities—such as changes in waveform time/amplitude, the presence of the omega sign, distortion and folding of RVCG loops, and alterations in loop direction in both the transverse and frontal planes—that are not easily discernible with a standard 12‑lead ECG. This enhanced detection aids in understanding the mechanisms underlying electrocardiographic changes and may assist in managing patients when diagnostic uncertainties arise.</p></div><div><h3>Methods</h3><p>Thirty-three patients undergoing elective PTCA were studied before and after acute LAD (16 patients) or RCA (17 patients) occlusion, and their data were processed with new methods based on PBLs, WULs, and RVCGs.</p></div><div><h3>Results</h3><p>1. In acute ischemia due to occlusion of the LAD and RCA, the most important current of injury occurs in the right to left axis. This axis is underestimated by the standard 12‑lead ECG and only partially complemented by leads V3R and V4R. 2. The two-dimensional presentation detects a new sign (the omega sign), not detectable in the classic ECG, but almost always present in ischemia. It also allows for an accurate identification of the J point. 3. Ischemic R wave peak delay results in distortion and folding of the RVCG loop and causes displacement of the J point and the ST segment. 4. Wave inversion changes the loop direction in the transverse and frontal plane.</p></div><div><h3>Conclusions</h3><p>Precordial bipolar leads, weighted unipolar leads, and regional vectorcardiograms provide essential information omitted by the standard 12‑lead ECG.</p></div>","PeriodicalId":15606,"journal":{"name":"Journal of electrocardiology","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142122666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of electrocardiographic criteria for predicting left ventricular hypertrophy and dilation in presence of left bundle branch block","authors":"Ashley DeBauge ,&nbsp;Christopher J. Harvey ,&nbsp;Amulya Gupta ,&nbsp;Tyan Fairbank ,&nbsp;Sagar Ranka ,&nbsp;Sania Jiwani ,&nbsp;Madhu Reddy ,&nbsp;Seth H. Sheldon ,&nbsp;Amit Noheria","doi":"10.1016/j.jelectrocard.2024.153787","DOIUrl":"10.1016/j.jelectrocard.2024.153787","url":null,"abstract":"<div><h3>Background</h3><div>The utility of standard published electrocardiographic (ECG) criteria for left ventricular hypertrophy (LVH) in patients with left bundle branch block (LBBB) is not established. We have previously shown that in ECGs demonstrating LBBB, QRS duration outperforms vectorcardiographic X, Y, Z lead and root-mean-squared (3D) amplitudes and voltage-time-integrals in diagnosing LVH and dilation. We sought to evaluate diagnostic yields of published LVH criteria versus QRS duration for ECG based diagnosis of LVH and dilation in presence of LBBB.</div></div><div><h3>Methods</h3><div>We included adult patients with typical LBBB having ECG and transthoracic echocardiogram performed within 3 months of each other in 2010–2020. We obtained area under receiver-operator characteristic curve (AUC) for QRS duration and each of the published ECG LVH criteria to predict increased LV mass indexed (↑LVMi, women &gt;95 g/m², men &gt;115 g/m²) and LV end diastolic volume indexed (↑LVEDVi, women &gt;61 mL/m², men &gt;74 mL/m²).</div></div><div><h3>Results</h3><div>Among 413 adults (53 % women, age 73 ± 12 yr) with LBBB, the traditional LVH criteria performed poorly to detect ↑LVMi or ↑LVEDVi. Cornell voltage-duration product had the highest AUCs (↑LVMi 0.634, ↑LVEDVi 0.580). QRS duration had a higher AUC for diagnosing ↑LVMi (women 0.657, men 0.703) and ↑LVEDVi (women 0.668, men 0.699) compared to any other criteria.</div></div><div><h3>Conclusions</h3><div>In patients with LBBB, prolonged QRS duration (women ≥150 ms, men ≥160 ms) is a superior predictor of LVH and dilation than traditional ECG-based LVH criteria.</div></div>","PeriodicalId":15606,"journal":{"name":"Journal of electrocardiology","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142347925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}