Journal of electrocardiology最新文献

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Cumulative electrocardiogram abnormalities predict left ventricular ejection fraction reduction: EchoNext database analysis 累积心电图异常预测左心室射血分数降低:EchoNext数据库分析
IF 1.2 4区 医学
Journal of electrocardiology Pub Date : 2026-03-01 Epub Date: 2026-01-06 DOI: 10.1016/j.jelectrocard.2026.154192
Solomon Kim MPH , Beshoy Saad BA , Gary Chu MD
{"title":"Cumulative electrocardiogram abnormalities predict left ventricular ejection fraction reduction: EchoNext database analysis","authors":"Solomon Kim MPH ,&nbsp;Beshoy Saad BA ,&nbsp;Gary Chu MD","doi":"10.1016/j.jelectrocard.2026.154192","DOIUrl":"10.1016/j.jelectrocard.2026.154192","url":null,"abstract":"<div><h3>Background</h3><div>Individual electrocardiographic abnormalities associate with reduced left ventricular ejection fraction (LVEF), but whether multiple continuous ECG parameters provide synergistic predictive value compared to single parameters or binary scoring remains incompletely characterized.</div></div><div><h3>Methods</h3><div>QRS duration, PR interval, and heart rate-corrected QT interval (QTc) from ECGs were analyzed in 89,630 paired ECG-echocardiogram studies from the EchoNext database. After systematic evaluation of missing data patterns revealing significant selection bias, the cohort was divided into training (70%, <em>n</em> = 62,741) and validation (30%, <em>n</em> = 26,889) sets using stratified sampling. Seven logistic regression models were developed, all adjusted for age and sex. Models were evaluated using bootstrap confidence intervals with 1000 iterations and 5-fold stratified cross-validation.</div></div><div><h3>Results</h3><div>The full continuous model achieved fair discrimination (AUC 0.710, 95% CI 0.699–0.714) compared to QTc alone (AUC 0.695, ΔAUC = 0.016, <em>p</em> &lt; 0.001). Among individual parameters, QTc demonstrated strongest association (AUC 0.695), followed by QRS duration (AUC 0.673) and PR interval (AUC 0.603). LVEF ≤45% prevalence increased from 15.9% (0 abnormalities) to 30.6% (1 abnormality), 49.5% (2 abnormalities), and 58.3% (3 abnormalities) (Cochran-Armitage Z = 76.0, <em>p</em> &lt; 0.001). At the optimal threshold, the model achieved sensitivity 59.9%, specificity 72.6%, positive predictive value 37.9%, and negative predictive value 86.7%. All models showed excellent calibration slopes (range 0.963–1.043). Cross-validation confirmed stability (CV AUC 0.706 ± 0.006).</div></div><div><h3>Conclusions</h3><div>Combined continuous ECG parameters provide predictive value for reduced LVEF compared to individual parameters or binary classifications. However, selection bias from non-random missing data (42.0% vs 21.8% outcome prevalence in incomplete vs complete cases, <em>p</em> &lt; 0.001) suggests findings likely underestimate true associations.</div></div>","PeriodicalId":15606,"journal":{"name":"Journal of electrocardiology","volume":"95 ","pages":"Article 154192"},"PeriodicalIF":1.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145940568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Tp-e interval and Tp-e/QT ratio as markers of ventricular repolarization dispersion and atrial conduction heterogeneity following electrical injury: A retrospective case-control study 电损伤后Tp-e间期和Tp-e/QT比值作为心室复极离散度和心房传导异质性的标志物:一项回顾性病例对照研究
IF 1.2 4区 医学
Journal of electrocardiology Pub Date : 2026-03-01 Epub Date: 2026-02-02 DOI: 10.1016/j.jelectrocard.2026.154202
Ahmet Yanik , Emre Ozgen , Faruk Boyacı , Murat Akcay , Mustafa Kursat Sahin
{"title":"The Tp-e interval and Tp-e/QT ratio as markers of ventricular repolarization dispersion and atrial conduction heterogeneity following electrical injury: A retrospective case-control study","authors":"Ahmet Yanik ,&nbsp;Emre Ozgen ,&nbsp;Faruk Boyacı ,&nbsp;Murat Akcay ,&nbsp;Mustafa Kursat Sahin","doi":"10.1016/j.jelectrocard.2026.154202","DOIUrl":"10.1016/j.jelectrocard.2026.154202","url":null,"abstract":"<div><h3>Background</h3><div>Electrical injuries are a significant cause of cardiovascular morbidity and life-threatening arrhythmias. This study aimed to evaluate markers of ventricular repolarization dispersion and atrial conduction heterogeneity, specifically, the Tp-e interval, Tp-e/QT ratio, and P-wave dispersion, in patients presenting with electrical injury</div></div><div><h3>Methods</h3><div>In this retrospective case-control study, 50 patients with electrical injury were compared with 59 age- and sex-matched healthy controls. Standard 12‑lead electrocardiograms were obtained for all participants. Key parameters, Tp-e interval, Tp-e/QT ratio, Tp-e/QTc ratio, and P-wave dispersion, were manually measured by two blinded cardiologists with excellent interobserver reliability. A subgroup analysis was also performed within the injury cohort based on troponin status</div></div><div><h3>Results</h3><div>The Tp-e interval was significantly prolonged in the electrical injury group compared to controls (median 85.0 ms vs. 80.0 ms, <em>p</em> &lt; 0.001). The Tp-e/QT ratio (0.24 vs. 0.21, p &lt; 0.001), Tp-e/QTc ratio (0.20 vs. 0.19, <em>p</em> = 0.005), and P-wave dispersion (45.0 ms vs. 25.0 ms, p &lt; 0.001) were also elevated in patients with electrical injury. Notably, no significant differences in these electrocardiographic parameters were observed between troponin-positive and troponin-negative subgroups</div></div><div><h3>Conclusion</h3><div>Electrical injury is associated with significant acute abnormalities in ventricular repolarization and atrial conduction heterogeneity, independent of troponin elevation. The Tp-e interval, Tp-e/QT ratio, and P-wave dispersion may serve as potential electrocardiographic markers of arrhythmic risk in this population, though their prognostic utility requires validation in prospective studies</div></div>","PeriodicalId":15606,"journal":{"name":"Journal of electrocardiology","volume":"95 ","pages":"Article 154202"},"PeriodicalIF":1.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146142359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The limits of the frontal QRS axis in modern electrocardiography 额位QRS轴在现代心电图中的局限性。
IF 1.2 4区 医学
Journal of electrocardiology Pub Date : 2026-03-01 Epub Date: 2026-02-12 DOI: 10.1016/j.jelectrocard.2026.154205
José Nunes de Alencar MD, FISHNE, FESC
{"title":"The limits of the frontal QRS axis in modern electrocardiography","authors":"José Nunes de Alencar MD, FISHNE, FESC","doi":"10.1016/j.jelectrocard.2026.154205","DOIUrl":"10.1016/j.jelectrocard.2026.154205","url":null,"abstract":"<div><h3>Background</h3><div>The frontal QRS axis is reported on every 12‑lead electrocardiogram (ECG) and is still taught as a precise geometric descriptor of ventricular depolarization. Contemporary biophysics and vectorcardiography, however, raise fundamental questions about what this number actually represents and how it should be used.</div></div><div><h3>Methods</h3><div>This conceptual review examines how the frontal QRS axis is computed in clinical practice, identifies the physical assumptions made, and contrasts axis-based interpretation with three-dimensional, time-integrated metrics.</div></div><div><h3>Results</h3><div>Ventricular depolarization is a three-dimensional, time-varying process that generates a QRS loop, not a single stable vector. The clinically reported “mean” QRS axis is derived from net limb‑lead amplitudes (typically R–S), algebraically adding sequential deflections as if they were simultaneous. This construct is therefore neither a true resultant vector nor a rigorous time average of the depolarization field, but an algebraic summary of projected amplitudes. Its numerical value depends on method choice, lead selection, and geometric approximations. By contrast, three-dimensional measures such as spatial QRS–T angle and vectorcardiographic QRS area preserve temporal integration and spatial information.</div></div><div><h3>Conclusions</h3><div>The frontal QRS axis should be regarded as a low-dimensional, categorical descriptor rather than a primary geometric truth. Hyper-precise angular reporting is not physically justified. Contemporary ECG practice and automated systems should prioritize spatial QRS–T angle, QRS area, and related vectorcardiographic indices, reserving the frontal axis for ordinal classification within a broader, three-dimensional framework.</div></div>","PeriodicalId":15606,"journal":{"name":"Journal of electrocardiology","volume":"95 ","pages":"Article 154205"},"PeriodicalIF":1.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146207175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
P-wave peak time: An emerging electrocardiographic marker of atrial stress and ischemic burden-review p波峰值时间:一个新兴的心房应激和缺血性负荷的心电图标记。
IF 1.2 4区 医学
Journal of electrocardiology Pub Date : 2026-03-01 Epub Date: 2026-02-15 DOI: 10.1016/j.jelectrocard.2026.154211
Allan J. Zhang , Mihail G. Chelu , Kimberly Taing , Yochai Birnbaum
{"title":"P-wave peak time: An emerging electrocardiographic marker of atrial stress and ischemic burden-review","authors":"Allan J. Zhang ,&nbsp;Mihail G. Chelu ,&nbsp;Kimberly Taing ,&nbsp;Yochai Birnbaum","doi":"10.1016/j.jelectrocard.2026.154211","DOIUrl":"10.1016/j.jelectrocard.2026.154211","url":null,"abstract":"<div><div>The 12‑lead electrocardiogram (ECG) remains a cornerstone of cardiovascular assessment, providing a noninvasive window into cardiac electrical and structural function beyond other markers of ischemia and arrhythmias. P-wave peak time (PWPT), defined as the interval from P-wave onset to its maximal amplitude, has emerged as a novel electrocardiographic marker of atrial conduction and hemodynamic stress. Increasing evidence suggests that PWPT prolongation accompanies elevated ventricular filling pressures, atrial stretch, and chronic atrial remodeling across a spectrum of ischemic conditions, including both obstructive coronary artery disease and ischemia with no obstructive coronary arteries (INOCA). In addition to serving as a marker of acute ischemia, PWPT also appears to capture long-term atrial structural and electrophysiologic changes, including fibrosis and conduction slowing. These same processes are central to the development of atrial fibrillation, providing a biologically plausible link between PWPT prolongation and arrhythmogenic risk. Moreover, given its simplicity and compatibility with computerized ECG analysis, PWPT represents a promising adjunctive marker for cardiovascular risk stratification. Further investigation in larger and more diverse populations is warranted to define its prognostic significance and clinical utility.</div></div>","PeriodicalId":15606,"journal":{"name":"Journal of electrocardiology","volume":"95 ","pages":"Article 154211"},"PeriodicalIF":1.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146258309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Validity of the single-limb electrocardiographic technology in the warfighter monitor™ 战士监护仪单肢心电图技术的有效性。
IF 1.2 4区 医学
Journal of electrocardiology Pub Date : 2026-03-01 Epub Date: 2026-02-15 DOI: 10.1016/j.jelectrocard.2026.154213
Pablo H. Vivas , Raimundo J. Acosta , Allen B. Kantrowitz , Kfir Ben-David , Harrison L. Wittels , Michael J. Wishon , S. Howard Wittels , Gerald Rosen
{"title":"Validity of the single-limb electrocardiographic technology in the warfighter monitor™","authors":"Pablo H. Vivas ,&nbsp;Raimundo J. Acosta ,&nbsp;Allen B. Kantrowitz ,&nbsp;Kfir Ben-David ,&nbsp;Harrison L. Wittels ,&nbsp;Michael J. Wishon ,&nbsp;S. Howard Wittels ,&nbsp;Gerald Rosen","doi":"10.1016/j.jelectrocard.2026.154213","DOIUrl":"10.1016/j.jelectrocard.2026.154213","url":null,"abstract":"<div><h3>Background</h3><div>Devices equipped with electrocardiographic (ECG) technology possess design limitations reducing their feasibility across a range of users and environments.</div></div><div><h3>Purpose</h3><div>This study evaluated the validity of a novel, single-limb biomedical device using single‑lead ECG technology located on the upper arm for monitoring cardiac activity in a large, diverse sample.</div></div><div><h3>Methods</h3><div>A cross-sectional study was conducted among 931 adults from May to September 2024 at an outpatient medical center in the United States. ECG recordings were captured on the Warfighter Monitor™ (WFM; Tiger Tech Solutions, Miami, FL). Each participant wore two ECGs simultaneously, a standard Lead-I ECG on the chest (ECG-Chest) and a WFM on the upper arm (ECG-Bicep), for 5 to 7 min. Agreement between ECG-Chest and ECG-Bicep measurements for HR and HRV were evaluated using Pearson correlations, Bland-Altman, and ANOVA.</div></div><div><h3>Results</h3><div>The study population was diverse in age (17–99 years), sex (53.4% male), and ethnicity (53.7% Hispanic or Latino), and comorbidities: cardiovascular (61.2%), respiratory (31.5%), cancer (20.3%), endocrine (43.4%), and neurological (32.5%) disorders. Near-perfect correlations (0.995–0.997, <em>p</em> &lt; 0.0001) and negligible mean differences (−0.02 to 0.05 bpm or ms, <em>p</em> &lt; 0.00001) were found between ECG-Chest and ECG-Bicep for HR and HRV metrics.</div></div><div><h3>Conclusion</h3><div>The near-perfect agreement in HR and HRV between ECG recordings measured at the chest and bicep, confirms the strong validity of the WFM for precise, ECG-based monitoring across a broad set of demographics. These results demonstrate the high accuracy, versatility, and feasibility of the WFM to accurately monitor HR and HRV.</div></div>","PeriodicalId":15606,"journal":{"name":"Journal of electrocardiology","volume":"95 ","pages":"Article 154213"},"PeriodicalIF":1.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146258237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Distinctive electrocardiographic pattern in acute myocardial infarction 急性心肌梗死的独特心电图模式。
IF 1.2 4区 医学
Journal of electrocardiology Pub Date : 2026-03-01 Epub Date: 2026-02-25 DOI: 10.1016/j.jelectrocard.2026.154217
János Tomcsányi, Előd Papp, Béla Bózsik
{"title":"Distinctive electrocardiographic pattern in acute myocardial infarction","authors":"János Tomcsányi,&nbsp;Előd Papp,&nbsp;Béla Bózsik","doi":"10.1016/j.jelectrocard.2026.154217","DOIUrl":"10.1016/j.jelectrocard.2026.154217","url":null,"abstract":"<div><div>Diffuse antero-inferior ST-elevation with typical chest pain most often reflects proximal.</div><div>RCA occlusion, wrap-around LAD occlusion, or multivessel disease.</div><div>We present a STEMI case with unique QRS and ST-segment pattern. The anterior chest leads V1, V2 and V3 mimic their augmented unipolar limb lead counterparts of aVR, aVL and aVF, respectively. This is best explained by the Littmann concept, which states that precordial leads V1–V3 reflect not only the horizontal electrocardiographic plane of the heart, but they also have strong frontal plane projection.</div></div>","PeriodicalId":15606,"journal":{"name":"Journal of electrocardiology","volume":"95 ","pages":"Article 154217"},"PeriodicalIF":1.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147321728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The value of ST-segment deviation in lead aVR for predicting the infarct-related artery in acute inferior STEMI: A systematic review and meta-analysis aVR导联st段偏差对预测急性下段STEMI梗死相关动脉的价值:系统回顾和荟萃分析
IF 1.2 4区 医学
Journal of electrocardiology Pub Date : 2026-03-01 Epub Date: 2026-01-20 DOI: 10.1016/j.jelectrocard.2026.154196
Yang-Yu Li , Fang Zeng , Ju Deng, Bin Huang, Guang-Dong Yan, Xi-Wei Chen, Biao Li, Yao-Gui Chen, Hui Yang, Qiang Zhao, Li Li
{"title":"The value of ST-segment deviation in lead aVR for predicting the infarct-related artery in acute inferior STEMI: A systematic review and meta-analysis","authors":"Yang-Yu Li ,&nbsp;Fang Zeng ,&nbsp;Ju Deng,&nbsp;Bin Huang,&nbsp;Guang-Dong Yan,&nbsp;Xi-Wei Chen,&nbsp;Biao Li,&nbsp;Yao-Gui Chen,&nbsp;Hui Yang,&nbsp;Qiang Zhao,&nbsp;Li Li","doi":"10.1016/j.jelectrocard.2026.154196","DOIUrl":"10.1016/j.jelectrocard.2026.154196","url":null,"abstract":"<div><h3>Background</h3><div>The infarct-related artery (IRA) in acute inferior wall ST-segment elevation myocardial infarction (inferior STEMI) is predominantly the left circumflex artery (LCX) or the right coronary artery (RCA). Electrocardiographic ST-segment deviation in lead aVR has shown potential value in predicting the IRA, but systematic evidence is lacking.</div></div><div><h3>Methods</h3><div>A comprehensive literature search was undertaken across Web of Science, PubMed, and Scopus to identify relevant studies published until March 2025. Pooled sensitivity and specificity were calculated using a bivariate effects model. Overall accuracy was quantified by the diagnostic odds ratio (DOR) and area under the curve (AUC).</div></div><div><h3>Results</h3><div>Twenty-four studies (6416 participants) were included. For LCX prediction, aVR ST-segment depression (aVR-STD) demonstrated pooled sensitivity of 0.62 (95% CI: 0.51–0.72), specificity of 0.81 (95% CI: 0.75–0.86), and good overall accuracy [DOR = 7.01 (95% CI: 3.72–13.22), AUC = 0.80 (95% CI: 0.76–0.83)]. Conversely, aVR ST-segment elevation (aVR-STE) was a poor predictor for LCX [sensitivity = 0.02 (95% CI: 0.01–0.08), AUC = 0.55 (95% CI: 0.51–0.59)]. For RCA prediction, aVR-STE demonstrated pooled sensitivity of 0.06 (95% CI: 0.03–0.13), specificity of 0.97 (95% CI: 0.93–0.98), and moderate overall accuracy [DOR = 1.99 (95% CI: 1.15–3.43), AUC = 0.75 (95% CI: 0.71–0.79)]. aVR-STD was a poor predictor for RCA [sensitivity = 0.19 (95% CI: 0.13–0.27), AUC = 0.23 (95% CI: 0.19–0.27)]. Heterogeneity analysis identified the ST-segment reference point and smoking history as potential contributors.</div></div><div><h3>Conclusion</h3><div>In inferior STEMI, aVR-STD demonstrates significant value in predicting LCX as the IRA, while its accuracy appears moderated by the ST-segment measurement reference point and smoking history. Conversely, aVR-STE shows limited predictive value for RCA.</div></div>","PeriodicalId":15606,"journal":{"name":"Journal of electrocardiology","volume":"95 ","pages":"Article 154196"},"PeriodicalIF":1.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146034299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Postoperative junctional ectopic tachycardia with variable QRS morphology: A case report 术后结性异位性心动过速伴可变QRS形态1例。
IF 1.2 4区 医学
Journal of electrocardiology Pub Date : 2026-03-01 Epub Date: 2026-02-11 DOI: 10.1016/j.jelectrocard.2026.154207
Luka Lovrenčić, Matija Bakoš
{"title":"Postoperative junctional ectopic tachycardia with variable QRS morphology: A case report","authors":"Luka Lovrenčić,&nbsp;Matija Bakoš","doi":"10.1016/j.jelectrocard.2026.154207","DOIUrl":"10.1016/j.jelectrocard.2026.154207","url":null,"abstract":"<div><div>Junctional ectopic tachycardia (JET) is a rare but clinically important arrhythmia most often encountered in infants and children, either congenitally or within 72 h after congenital heart surgery. We report a neonate who developed postoperative JET with variable QRS morphologies after an arterial switch operation, in whom QP interval and QRS duration correlated with the preceding RR interval. The arrhythmia caused hemodynamic instability requiring antiarrhythmic therapy and supportive measures. This case illustrates the diverse electrocardiographic manifestations of postoperative JET and highlights the importance of early rhythm characterization to guide timely, mechanism-based management in critically ill neonates.</div></div>","PeriodicalId":15606,"journal":{"name":"Journal of electrocardiology","volume":"95 ","pages":"Article 154207"},"PeriodicalIF":1.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146213340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Malignant arrhythmia risk assessment based on lead-I mobile ECG measurements using machine learning 基于机器学习的铅- i移动心电图测量的恶性心律失常风险评估。
IF 1.2 4区 医学
Journal of electrocardiology Pub Date : 2026-03-01 Epub Date: 2026-01-13 DOI: 10.1016/j.jelectrocard.2026.154194
Gergely Tuboly , Orsolya Kiss , Máté Babity , Márk Zámodics , Béla Merkely , György Kozmann , Mohamed F. Issa
{"title":"Malignant arrhythmia risk assessment based on lead-I mobile ECG measurements using machine learning","authors":"Gergely Tuboly ,&nbsp;Orsolya Kiss ,&nbsp;Máté Babity ,&nbsp;Márk Zámodics ,&nbsp;Béla Merkely ,&nbsp;György Kozmann ,&nbsp;Mohamed F. Issa","doi":"10.1016/j.jelectrocard.2026.154194","DOIUrl":"10.1016/j.jelectrocard.2026.154194","url":null,"abstract":"<div><div>This paper presents an algorithm capable of estimating malignant arrhythmia risk based on a short lead-I ECG record. We chose the mean and relative standard deviation of beat-to-beat QRST integrals as feature parameters. The algorithm was trained on a learning set consisting of three subgroups: 55 healthy subjects, 48 patients without malignant arrhythmia history, and 48 malignant arrhythmia patients. These subgroups represented the normal, moderate, and high risk, respectively. The 3 nearest neighbors (3−NN), and the 1-D and 2-D Bayesian classifiers were used as supervised machine-learning techniques. The test set contained ECG signals of 63 healthy subjects and 52 patients with confirmed malignant arrhythmia records. We obtained the best classification results with the 2-D Bayesian classifier, which produced a decision efficiency of 87.30% and 94.23% for the normal and malignant arrhythmia cases, respectively. Slightly lower results were achieved by the 3-NN method (80.95%, 94.23%) and the 1-D Bayesian classifier (77.78%, 94.23%). Considering the QTc parameter instead of the QRST integral produced a relatively low decision efficiency in the malignant arrhythmia case (84.62%). The proposed method performs best with the 2-D Bayesian method, while it is still efficient with the 3-NN classifier. According to our current knowledge, our algorithm is the first one which only requires a single-channel ECG as input and efficiently estimates malignant arrhythmia risk at the same time. As the proposed method relies only on lead-I ECG, it can be very useful in mobile ECG systems (e.g., in WIWE), making out-of-hospital risk assessment possible.</div></div>","PeriodicalId":15606,"journal":{"name":"Journal of electrocardiology","volume":"95 ","pages":"Article 154194"},"PeriodicalIF":1.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146029642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Electrocardiogram-based false positive diagnosis of left ventricular hypertrophy during tachycardia: What more needs to be done 心动过速时左室肥厚的心电图假阳性诊断:还需要做些什么
IF 1.2 4区 医学
Journal of electrocardiology Pub Date : 2026-03-01 Epub Date: 2026-02-11 DOI: 10.1016/j.jelectrocard.2026.154206
John E. Madias MD, FACC, FAHA
{"title":"Electrocardiogram-based false positive diagnosis of left ventricular hypertrophy during tachycardia: What more needs to be done","authors":"John E. Madias MD, FACC, FAHA","doi":"10.1016/j.jelectrocard.2026.154206","DOIUrl":"10.1016/j.jelectrocard.2026.154206","url":null,"abstract":"<div><div>This short communication aims at raising an insight about an observation made 26 years ago, describing a transient false positive electrocardiogram (ECG)-based diagnosis of left ventricular hypertrophy (LVH) in patients with various tachycardias (e.g, sinus, supraventricular, atrial fibrillation) with or without evidence of LVH as assessed by cardiac imaging. The mechanism is purported to be due to a tachycardia-mediated shortening of the diastolic left ventricular (LV) dimensions due to tachycardias, with the diastolic LV volume centroid displaced closer to the anterior chest wall (e.g. “Wilson's proximity effect”). This insight prevents an inappropriate diagnosis of LVH; also, it is possible that the absence of such a phenomenon during tachycardias may imply in some cases advanced acute or chronic heart failure, resulting in LV diastolic dilatation, counteracting this ECG phenomenon. The author advocates that automated ECG interpretation algorithms providing interpretation upon recording of an ECG should be modified to reflect on this insight, since many physicians rely inappropriately on the automated ECG interpretation.</div></div>","PeriodicalId":15606,"journal":{"name":"Journal of electrocardiology","volume":"95 ","pages":"Article 154206"},"PeriodicalIF":1.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146189089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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