Journal of Dental Research, Dental Clinics, Dental Prospects最新文献

{"title":"Influence of composite resin type and curing method on the fracture resistance of class II restorations: An in vitro comparison.","authors":"Gianella Haydee Vidal-Castillo, Fredy Hugo Cruzado-Oliva, Luis Felipe Alarco-La Rosa","doi":"10.34172/joddd.025.43966","DOIUrl":"10.34172/joddd.025.43966","url":null,"abstract":"<p><strong>Background: </strong>The selection of the restorative material and the use of inadequate curing protocols can affect the mechanical performance of composite resin restorations. This in vitro study aimed to determine the influence of restorative material type and curing method on the fracture resistance of restorations with proximal involvement.</p><p><strong>Methods: </strong>A total of 120 extracted human molars were selected, and Cl II cavities (OM) were prepared, maintaining consistent dimensions across all teeth. The samples were randomly divided into two experimental groups: teeth restored with a nanohybrid composite resin (Filtek Z350XT) and teeth restored with Ormocer-based composite resin (Admira Fusion). Each group was further subdivided according to the curing method: pre-curing, co-curing, and simultaneous curing. In addition, two control groups were included: a negative control consisting of prepared but unrestored teeth, and a positive control consisting of intact, sound teeth. Fracture resistance was evaluated using a universal testing machine. Data were analyzed using two-way ANOVA and post hoc Tukey tests (α=0.05).</p><p><strong>Results: </strong>Two-way ANOVA revealed significant effects of both the composite resin type (F=1750.4, <i>P</i><0.001) and the curing method (F=210.6, <i>P</i><0.001) on fracture resistance, with a significant interaction between the factors (<i>P</i>=0.002). The Ormocer-based composite resin exhibited higher fracture resistance than the nanohybrid composite resin across all curing methods. Within each composite type, the simultaneous curing method showed the highest fracture resistance, followed by co-curing and pre-curing.</p><p><strong>Conclusion: </strong>The fracture resistance of Cl II composite resin restorations was significantly influenced by both the composite formulation and the curing protocol.</p>","PeriodicalId":15599,"journal":{"name":"Journal of Dental Research, Dental Clinics, Dental Prospects","volume":"19 4","pages":"242-249"},"PeriodicalIF":0.0,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13179455/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147963940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the color-matching potentials of different universal composite resins with natural tooth structure in class III through-and-through cavities using a visual guide and spectrophotometer.","authors":"Mahmoud Bahari, Mahdi Abed Kahnamouei, Fatemeh Pournaghi Azar, Soodabeh Kimyai, Kiana Tadayon","doi":"10.34172/joddd.025.42343","DOIUrl":"10.34172/joddd.025.42343","url":null,"abstract":"<p><strong>Background: </strong>This study assessed the color-matching potentials of Omnichroma single-shade composite resin and Omnichroma Blocker with natural tooth structure in Class III through-and-through restorations and compared them with a universal multi-shade composite resin using both visual and spectrophotometric evaluations.</p><p><strong>Methods: </strong>Class III through-and-through cavities were prepared on the mesial and distal aspects of 32 extracted anterior teeth. Each preparation was restored with either Omnichroma composite resin or Tetric Evoceram composite resin, with or without an 0.5-mm depth of Omnichroma Blocker on the lingual aspect. Color measurements were performed initially and after restoration using visual evaluation with the VITA Classical Shade Guide and the SpectroShade microspectrophotometer. Color differences were calculated using the CIEDE2000 formula.</p><p><strong>Results: </strong>Tetric Evoceram with and without blocker exhibited a statistically significant difference in color match with natural tooth structure (<i>P</i>=0.02). The color-matching difference with natural teeth was statistically significant in the visual evaluation (<i>P</i>=0.005).</p><p><strong>Conclusion: </strong>Failing to use a blocker with Tetric Evoceram composite resin in large Class III cavities reduced color matching. In contrast, using a blocker with Omnichroma composite resin did not affect the final color-matching ability. Furthermore, the Omnichroma composite resin demonstrated better visual color matching, regardless of the presence of a blocker, than the Tetric Evoceram composite resin.</p>","PeriodicalId":15599,"journal":{"name":"Journal of Dental Research, Dental Clinics, Dental Prospects","volume":"19 4","pages":"250-258"},"PeriodicalIF":0.0,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13179452/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147963791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Flow cytometry for assessing pulp viability in pediatric dentistry: An exploratory study.","authors":"Josué Zuriel Ortiz García, Ismael Secundino, José Luis Ayala Herrera, Alejandro Nava Carmona, Erika Cortes Guzmán, Gloria Ariadna Luevano García, Claudia María Alfaro León, Sandra Liliana Morales Cabrera","doi":"10.34172/joddd.025.44083","DOIUrl":"10.34172/joddd.025.44083","url":null,"abstract":"<p><strong>Background: </strong>Dental pulp (DP) in pediatric patients plays a vital role in dentin formation, nutrition, protection, and tooth repair. Pulpal pathologies are a common reason for pediatric dental visits; however, accurate clinical diagnosis can be challenging, particularly in young patients and those with limited cooperation. Currently, no reliable clinical method exists to definitively determine pulp viability, and histopathological diagnosis remains the gold standard despite its invasiveness. Flow cytometry has proven effective in cellular analysis across biomedical fields and was used in this study to assess pulp viability in pediatric patients with various pulpal conditions.</p><p><strong>Methods: </strong>Forty-four pulp samples from pediatric patients aged 2-7 years were classified as healthy pulp (HP), reversible pulpitis (RP), irreversible pulpitis (IP), and pulp necrosis (PN). Flow cytometry using 7-aminoactinomycin D (7-AAD) staining was employed to assess cell viability. Total protein extracts were obtained from each group for SDS-PAGE analysis of protein profiles. Proteolytic activity was evaluated through gelatin zymography to detect matrix metalloproteinase (MMP) activity.</p><p><strong>Results: </strong>Flow cytometry effectively quantified viable cells across diagnostic categories, revealing minimal differences in viability between HP, RP, and IP, which may explain the clinical challenge of differentiating these conditions. Protein profile analysis showed a progressive reduction in the number of protein bands as pulpal disease advanced, although some bands remained consistent. Proteolytic activity, likely associated with MMP-2, increased with disease progression and was significantly elevated in PN compared to other groups.</p><p><strong>Conclusion: </strong>Flow cytometry proved a valuable tool for quantifying pulp cell viability in pediatric patients, highlighting the narrow clinical distinction between pulpal conditions. Protein profiling suggests the potential to identify diagnostic biomarkers that support less invasive diagnostic approaches. Although matrix metalloproteinase-2 (MMP-2) activity was present in all stages of pulpal disease, it could not be confirmed as a specific biomarker for disease progression.</p>","PeriodicalId":15599,"journal":{"name":"Journal of Dental Research, Dental Clinics, Dental Prospects","volume":"19 4","pages":"272-278"},"PeriodicalIF":0.0,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13179454/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147963912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of debris extrusion during retreatment using two different File systems and two irrigation activation systems.","authors":"Selen İnce Yusufoglu, Beyza Turan Saglam, Feyza Nur Ergüner","doi":"10.34172/joddd.025.42344","DOIUrl":"10.34172/joddd.025.42344","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to assess the quantity of apically extruded debris generated during root canal retreatment.</p><p><strong>Methods: </strong>Sixty single-rooted teeth were shaped and obturated with gutta-percha and a resin-based sealer. After three weeks, the samples were prepared for retreatment. They were then divided into four groups (n=15): OneShape+PUI, OneShape+EasyDoActivator, Reciproc+PUI, and Reciproc+EasyDoActivator. Apically extruded debris was gathered and placed in previously weighed Eppendorf tubes. The data were statistically analyzed.</p><p><strong>Results: </strong>With ultrasonic irrigation, debris extrusion was noticeably higher with the OneShape system (<i>P</i>=0.0001). In the Reciproc system, significantly more debris extrusion occurred with sonic activation than with ultrasonic activation (<i>P</i>=0.0001), while no significant difference was observed between irrigation activation systems for the OneShape system (<i>P</i>=0.841). The OneShape+EasyDoActivator group showed significantly higher debris extrusion than Reciproc+PUI (<i>P</i>=0.002).</p><p><strong>Conclusion: </strong>Given the constraints of this study, the Reciproc file system with PUI resulted in less apical debris extrusion, proving safer in terms of periapical extrusion compared to other systems.</p>","PeriodicalId":15599,"journal":{"name":"Journal of Dental Research, Dental Clinics, Dental Prospects","volume":"19 4","pages":"222-226"},"PeriodicalIF":0.0,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13179460/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147963788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of patients' oral health-related quality of life and chewing efficiency between conventional and 3D-printed complete dentures: A crossover clinical trial.","authors":"Radwa Mohsen Kamal Emera, Zeena Farhan Al Sultani, Fatma Fathe Mahanna","doi":"10.34172/joddd.025.44430","DOIUrl":"10.34172/joddd.025.44430","url":null,"abstract":"<p><strong>Background: </strong>Additive manufacturing has introduced novel materials and workflows for complete denture fabrication; however, high-quality clinical evidence comparing patient-centered outcomes of 3D-printed and conventionally fabricated dentures remains limited. This compared oral health-related quality of life (OHRQoL) and chewing efficiency between conventional and 3D-printed dimethacrylate-based resin complete dentures.</p><p><strong>Methods: </strong>Twenty completely edentulous patients were enrolled in this randomized two-period crossover clinical trial. Each participant received both interventions-conventional complete dentures and 3D-printed dimethacrylate-based resin complete dentures-in a randomized sequence. OHRQoL was assessed using the Oral Health Impact Profile for Edentulous Patients (OHIP-EDENT), and chewing efficiency was evaluated using a two-colored chewing gum mixing ability test by calculating the standard deviation of hue (H-SD). Assessments were performed at insertion (T₀), after 3 months (T₃), and after 6 months (T₆). Normality was assessed using the Shapiro-Wilk test. Intra-subject comparisons were conducted using the Wilcoxon signed-rank test for OHIP-EDENT scores and paired t-tests for chewing efficiency. Statistical significance was set at <i>P</i>≤0.05.</p><p><strong>Results: </strong>No statistically significant differences were observed between conventional and 3D-printed dentures regarding overall OHIP-EDENT scores or individual domains at T₀, T₃, or T₆ (<i>P</i>>0.05). Both denture types demonstrated significant improvements in OHRQoL from the pre-treatment period to T₆ (<i>P</i><0.05). Similarly, chewing efficiency showed no significant differences between denture types across all chewing cycles (<i>P</i>>0.05).</p><p><strong>Conclusion: </strong>Within the limitations of this randomized crossover study, 3D-printed dimethacrylate-based resin complete dentures demonstrated clinical performance and satisfaction comparable to conventional dentures, supporting their use as a reliable alternative in complete denture rehabilitation.</p>","PeriodicalId":15599,"journal":{"name":"Journal of Dental Research, Dental Clinics, Dental Prospects","volume":"19 4","pages":"233-241"},"PeriodicalIF":0.0,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13179461/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147963784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of single and repeated potassium iodide applications versus glutathione on silver diamine fluoride-induced tooth discoloration in primary teeth: An in vitro comparative study.","authors":"Maryam Hajiahmadi, Samira SadighBatha, Mohammad Javad Tarrahi","doi":"10.34172/joddd.025.43876","DOIUrl":"10.34172/joddd.025.43876","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to evaluate the effects of a single application of potassium iodide (KI), repeated daily applications of KI, and glutathione (GSH) on silver diamine fluoride (SDF)-induced tooth discoloration in primary canines.</p><p><strong>Methods: </strong>This in vitro study was performed on 36 extracted primary canines with dentinal caries, which were randomly assigned to four treatment groups: A (38% SDF alone), B (38% SDF+immediate single application of KI), C (38% SDF+repeated daily KI applications), and D (38% SDF+20% GSH). Color changes were measured at baseline and after 1, 14, and 30 days using a spectrophotometer and the CIEL*a*b* system. Statistical analysis included one-way ANOVA with post hoc Tukey tests for inter-group comparisons, and repeated-measures ANOVA with Bonferroni's correction for intra-group comparisons.</p><p><strong>Results: </strong>Significant differences in tooth discoloration (ΔE) were observed between the study groups at all time intervals (<i>P</i><0.001). Group A showed the highest discoloration, while group D exhibited the lowest. Among the KI-treated groups, group B showed progressive discoloration over time, while group C demonstrated minimal changes, with no statistically significant differences between time intervals (<i>P</i>=0.435). Although groups C and D both showed reduced discoloration compared to group B, the difference between them was not statistically significant on day 30 (<i>P</i>=0.073).</p><p><strong>Conclusion: </strong>Repeated daily applications of KI or GSH effectively reduced SDF-induced tooth discoloration in primary canines. GSH showed the most favorable esthetic outcomes, suggesting its potential as a promising adjunct to SDF.</p>","PeriodicalId":15599,"journal":{"name":"Journal of Dental Research, Dental Clinics, Dental Prospects","volume":"19 4","pages":"215-221"},"PeriodicalIF":0.0,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13179459/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147963800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of polyacrylic acid pretreatment before CPP-ACP application in remineralization of demineralized root dentin: An in vitro study.","authors":"Arezoo Ghasemi, Elmira Jafari Navimipour, Soodabeh Kimyai, Parnian Alizadeh Oskuee, Mehdi Daneshpooy, Ziba Islambulchilar, Sevda Riyahifar","doi":"10.34172/joddd.025.43997","DOIUrl":"10.34172/joddd.025.43997","url":null,"abstract":"<p><strong>Background: </strong>This study evaluated the efficacy of polyacrylic acid (PAA) pretreatment before application of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) in remineralizing demineralized root dentin.</p><p><strong>Methods: </strong>Thirty-nine dentin specimens from extracted human third molars were prepared. All the specimens were standardized for Vickers microhardness at baseline (VHNba). Then the specimens were randomly divided into three groups (n=13): (1) untreated demineralized dentin, (2) CPP-ACP treatment, and (3) PAA pretreatment before CPP-ACP application. All the specimens were subjected to 72 hours of demineralization. Subsequently, treatments were administered according to group protocols and a 28-day pH-cycling regimen. Then, Vickers microhardness (VHN) was assessed after demineralization (VHNde) and after treatment (VHNre). The difference between VHNre and VHNde was calculated as ΔVHN and compared between the groups. Data were analyzed using one-way ANOVA, repeated-measures ANOVA, and post hoc Bonferroni tests (P<0.05).</p><p><strong>Results: </strong>Demineralization significantly decreased dentin microhardness in all the groups (<i>P</i><0.001). In contrast, microhardness values increased significantly after applying the treatment protocol (<i>P</i><0.001). Specimens that received PAA pretreatment before CPP-ACP application showed a considerably higher ΔVHN than those treated with CPP-ACP alone (<i>P</i><0.0001). However, neither group returned to the initial values.</p><p><strong>Conclusion: </strong>Applying CPP-ACP, either alone or after pretreatment with PAA, increased the microhardness of demineralized root dentin and promoted remineralization. Pretreatment with PAA enhanced this remineralization effect, suggesting its potential use in conservative dentin treatment strategies.</p>","PeriodicalId":15599,"journal":{"name":"Journal of Dental Research, Dental Clinics, Dental Prospects","volume":"19 4","pages":"227-232"},"PeriodicalIF":0.0,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13179453/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147963798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The implication gap: Why evidence-based dental guidelines fall short in clinical settings.","authors":"Naser Asl Aminabadi, Katayoun Katebi","doi":"10.34172/joddd.025.44440","DOIUrl":"10.34172/joddd.025.44440","url":null,"abstract":"","PeriodicalId":15599,"journal":{"name":"Journal of Dental Research, Dental Clinics, Dental Prospects","volume":"19 4","pages":"213-214"},"PeriodicalIF":0.0,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13179456/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147963857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychological factors and salivary biomarkers (cortisol and opiorphin) in erosive oral lichen planus: A case-control study.","authors":"Samira Hajisadeghi, Yasamin Barakian, Robabe Yeganeh, Reza Fotouhi Ardakani, Mohammad Aghaali, Elham Keykha","doi":"10.34172/joddd.025.43995","DOIUrl":"10.34172/joddd.025.43995","url":null,"abstract":"<p><strong>Background: </strong>Oral lichen planus (OLP) is a persistent inflammatory condition associated with the immune system. Its etiology remains unclear; nevertheless, it seems that individuals with OLP have elevated levels of stress, anxiety, depression, and salivary cortisol. On the other hand, it is expected that the extent of salivary opiorphin changes in the orofacial pain and inflammatory lesions will be high. Moreover, stress, anxiety, depression, salivary cortisol, and salivary opiorphin may affect the perception of pain in OLP patients.</p><p><strong>Methods: </strong>This case‒control study included 42 participants: 21 patients with OLP and 21 healthy individuals. The Beck Depression Inventory (BDI), the Perceived Stress Scale (PSS) 14, the Visual Analog Scale (VAS), and the Beck Anxiety Inventory (BAI) were employed to evaluate depression, stress, perceived pain, and anxiety in the case group, respectively. Salivary samples were also collected. Statistical analysis was conducted using SPSS and MEDCALC software at the 0.05 significance level.</p><p><strong>Results: </strong>The level of salivary opiorphin was significantly lower in the case group (<i>P</i><0.0001). Also, salivary cortisol in the case group was significantly higher (<i>P</i><0.0001). The correlation between patient age and salivary opiorphin level was significant (<i>P</i>=0.03). Salivary opiorphin levels decreased with age. In addition, opiorphin was significantly higher in men than in women (<i>P</i>=0.02).</p><p><strong>Conclusion: </strong>The present study found that in patients with erosive OLP, salivary opiorphin levels were lower and salivary cortisol levels were higher than in healthy individuals.</p>","PeriodicalId":15599,"journal":{"name":"Journal of Dental Research, Dental Clinics, Dental Prospects","volume":"19 4","pages":"265-271"},"PeriodicalIF":0.0,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13179457/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147963918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serum levels of vitamin E, vitamin D, and omega-3 fatty acids in patients with generalized chronic periodontitis: A cross-sectional study.","authors":"Shima Ghasemi, Amirreza Babaloo, Mohammadtaghi Chitsazi, Atiyeh Ghassemi, Saeid Forghani","doi":"10.34172/joddd.025.42534","DOIUrl":"10.34172/joddd.025.42534","url":null,"abstract":"<p><strong>Background: </strong>The present study aimed to investigate the serum levels of vitamin D, vitamin E, and omega-3 in patients with chronic periodontitis.</p><p><strong>Methods: </strong>Thirty-six patients with periodontitis participated in this cross-sectional descriptive study. Clinical parameters such as the gingival index, pocket depth (PD) (mm), and clinical attachment loss (CAL) (mm) were measured. Serum samples were obtained and analyzed for levels of vitamin D, vitamin E, and omega-3 fatty acids. The data were analyzed using SPSS 24, and a probability value of<0.05 was considered statistically significant.</p><p><strong>Results: </strong>All the clinical parameters used to measure periodontal status differed significantly according to the severity of periodontitis (<i>P</i><0.05). The mean serum levels of all vitamins and omega-3 fatty acids were lower in the severe periodontitis group than in the moderate periodontitis group. The mean levels were high in the mild periodontitis group. However, the differences were significant only for vitamin E and vitamin D (<i>P</i><0.05). No statistically significant effect was observed for omega-3 fatty acids, but higher amounts of omega-3 fatty acids were detected in mild periodontitis patients than in moderate and severe periodontitis patients.</p><p><strong>Conclusion: </strong>It can be concluded that the optimal consumption of vitamin E and vitamin D, either as supplements or as part of an individual's daily diet, may contribute to maintaining periodontal health.</p>","PeriodicalId":15599,"journal":{"name":"Journal of Dental Research, Dental Clinics, Dental Prospects","volume":"19 4","pages":"259-264"},"PeriodicalIF":0.0,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13179458/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147963896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}