Journal of Dental Research, Dental Clinics, Dental Prospects最新文献

{"title":"Association Between Periodontal Disease and OHRQoL in Substance Use Disorder: A Cross-Sectional Study at the Lido Rehabilitation Center.","authors":"Nadira Zahrani Effendi, Marie Louisa, Tiarma Talenta Theresia, Chrisanty Anastasia Parorrongan, Anzany Tania Dwi Putri","doi":"10.34172/joddd.42164","DOIUrl":"10.34172/joddd.42164","url":null,"abstract":"<p><strong>Introduction: </strong>Substance use is one of the unresolved health problems in Indonesia. It has several impacts on oral health, including xerostomia, caries, mucosal infection, and periodontal disease. Periodontal disease is a silent disease. If left untreated, it can cause tooth mobility and tooth loss, impairing essential functions like chewing and speaking, self-confidence, and an individual's quality of life. Although most oral health problems are not life-threatening, they can significantly impact oral health-related quality of life (OHRQoL) by causing prolonged pain and discomfort. This study examined the association between periodontal disease and OHRQoL among individuals with substance use disorder at the BNN Lido Rehabilitation Center.</p><p><strong>Methods: </strong>This analytical, observational study, using a cross-sectional design, was conducted in August 2024 at Lido Rehabilitation Center in Indonesia. This study involved 101 patients in drug rehabilitation. Primary data were obtained by completing the OHIP-14 questionnaire (7 domains, 14 questions) and performing periodontal examinations. Sociodemographic data were obtained from Lido Rehabilitation Center.</p><p><strong>Results: </strong>Respondents with periodontal disease had a higher OHIP-14 score than healthy respondents. It showed that the group with periodontal disease had a poor quality of life, although this difference was not statistically significant.</p><p><strong>Conclusion: </strong>The prevalence of periodontal disease was 63.4% in respondents. Respondents with healthy periodontal health had a better quality of life than those with gingivitis or periodontitis, although the difference was not statistically significant.</p>","PeriodicalId":15599,"journal":{"name":"Journal of Dental Research, Dental Clinics, Dental Prospects","volume":"20 1","pages":"50-55"},"PeriodicalIF":0.0,"publicationDate":"2026-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13402665/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148603759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimized Analysis of Cervical Vertebrae Maturation in Cone-Beam Computed Tomography: A Cross-Sectional Study.","authors":"Bárbara Pilla Tavares, Kelly Galisteu-Luiz, Luciana Duarte Caldas, Luciano Santos Pinto Guimarães, Lincoln Issamu Nojima, Maria Augusta Visconti, Matilde da Cunha Gonçalves Nojima","doi":"10.34172/joddd.42445","DOIUrl":"10.34172/joddd.42445","url":null,"abstract":"<p><strong>Introduction: </strong>Cone-beam computed tomography (CBCT) scans are widely used in dentistry as a valuable and accurate research tool for assessing skeletal age. This study aimed to conduct an optimized analysis of cervical vertebrae maturation using pre-existing CBCT images and compare the findings with mandibular growth stages.</p><p><strong>Methods: </strong>Seventy-five participants evaluated 24 CBCT images, from which 12 lateral cephalometric projections (Cef2D) and 12 sagittal tomographic reconstructions (Rec2D) were extracted. The inferior borders of the C2, C3, and C4 vertebrae, as well as the shapes of C3 and C4, were analyzed according to the cervical vertebral maturation (CVM) method proposed by Baccetti et al. (2005). The degree of reproducibility was assessed using Cohen's kappa coefficient.</p><p><strong>Results: </strong>The analysis of intra- and inter-examiner reproducibility for the inferior borders of the cervical vertebrae and the classification of maturation stages showed almost perfect and substantial levels of agreement, respectively. These results were consistent for both Cef2D and Rec2D images. When mandibular growth stages were grouped, the reproducibility of the CVM method also reached an almost perfect level of agreement for both image types.</p><p><strong>Conclusion: </strong>The analysis of CVM, adapted from the method by Baccetti et al. (2005) for CBCT, demonstrated a high level of reproducibility, particularly when evaluating the inferior borders of the C2, C3, and C4 vertebrae and when grouping post-peak stages of mandibular growth.</p>","PeriodicalId":15599,"journal":{"name":"Journal of Dental Research, Dental Clinics, Dental Prospects","volume":"20 1","pages":"18-24"},"PeriodicalIF":0.0,"publicationDate":"2026-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13402842/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148603876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring BMI and DMFT Indexes of Male Islamic Boarding School Students in Indonesia: A Cross-Sectional Study.","authors":"Laifa Annisa Hendarmin, Muhammad Faiza Ma'ruf, Risahmawati Risahmawati, Witri Ardini, Sarah At Tauhidah","doi":"10.34172/joddd.44130","DOIUrl":"10.34172/joddd.44130","url":null,"abstract":"<p><strong>Introduction: </strong>Adolescent health reflects both nutritional and oral conditions, which share dietary and behavioral risk factors. In Muslim societies, Islamic boarding schools (<i>pesantren</i>) shape adolescent lifestyles through communal meals, structured routines, and religious values of cleanliness. Their students, called <i>santri</i>, represent a unique adolescent population. This study examined the relationship between the body mass index (BMI) and dental caries experience, measured by the decayed, missing, and filled teeth (DMFT) index, among male santri in Indonesia.</p><p><strong>Methods: </strong>A cross-sectional study was conducted in 2024 among 85 male santri at an Islamic boarding school in Bogor, Indonesia. BMI was classified according to CDC-2000 growth charts. Dental caries experience was assessed using the WHO DMFT index. Descriptive statistics summarized BMI and DMFT distributions. Associations were evaluated using the chi-squared or Fisher's exact test.</p><p><strong>Results: </strong>Most participants had normal BMI (65.9%), while 18.8% were overweight, and 10.6% were obese. Regarding oral health, 55.3% had very low DMFT scores, and 10.6% had high or very high caries experience. No significant association was observed between BMI and DMFT categories (<i>P</i>=0.276).</p><p><strong>Conclusion: </strong>Although no significant association was identified, the coexistence of obesity and high caries in a subset of santri indicates a dual public health concern. These findings warrant further investigation and highlight the need for preventive strategies addressing both nutrition and oral health in Islamic boarding school settings.</p>","PeriodicalId":15599,"journal":{"name":"Journal of Dental Research, Dental Clinics, Dental Prospects","volume":"20 1","pages":"32-35"},"PeriodicalIF":0.0,"publicationDate":"2026-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13402841/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148603836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Different Sealers and Irrigants on the Push-Out Bond Strength of Fiber Posts to The Root Canal.","authors":"Funda Fundaoğlu Küçükekenci","doi":"10.34172/joddd.44101","DOIUrl":"10.34172/joddd.44101","url":null,"abstract":"<p><strong>Introduction: </strong>This study evaluated the effects of bioceramic and resin-based root canal sealers and different irrigation protocols on the push-out bond strength (PBS) of fiber posts.</p><p><strong>Methods: </strong>Fifty-four freshly extracted mandibular canines were instrumented and irrigated with NaOCl and EDTA. The specimens were first divided into two groups based on the sealer used: a bioceramic sealer (Bioserra) or a resin-based sealer (AH Plus) (n=27 per group). Each group was then randomly subdivided into three subgroups (n=9) based on the irrigation solution used for smear layer removal during post space preparation: distilled water, 17% EDTA, or 0.2% chitosan. Fiber posts were cemented with self-adhesive resin cement. Sections (1.5-mm thick) from the coronal third were subjected to a push-out bond strength test. Data was analyzed using two-way ANOVA and post hoc Bonferroni tests (α=0.05).</p><p><strong>Results: </strong>Both the type of sealer and the irrigation protocol significantly influenced PBS values (<i>P</i><0.05). The highest PBS was observed in the bioceramic sealer+chitosan group (16.08±0.48 MPa), whereas the lowest value was recorded in the bioceramic sealer+distilled water group (11.20±0.58 MPa).</p><p><strong>Conclusion: </strong>Root canal sealer type and irrigation protocol during post space preparation significantly affected the bond strength of fiber posts. Chitosan irrigation demonstrated superior performance, suggesting its potential to improve post retention.</p>","PeriodicalId":15599,"journal":{"name":"Journal of Dental Research, Dental Clinics, Dental Prospects","volume":"20 1","pages":"36-42"},"PeriodicalIF":0.0,"publicationDate":"2026-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13402840/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148603745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Calcium Silicate-Based Sealer Residues on Adhesive Bonding to Coronal Dentin: An in Vitro Study.","authors":"Mariana Bena Gelio, Thais Piragine Leandrin, Ana Lídia Pinheiro Silva Sato, Milton Carlos Kuga, Joissi Ferrari Zaniboni","doi":"10.34172/joddd.44162","DOIUrl":"10.34172/joddd.44162","url":null,"abstract":"<p><strong>Introduction: </strong>This study aimed to evaluate the influence of residues from three endodontic sealers on the adhesive interface of two universal adhesive systems: Scotchbond Universal (SU) and OptiBond All-in-One (OU).</p><p><strong>Methods: </strong>Forty bovine dentin surfaces were cleaned with 95% ethanol and divided into 4 groups: control, without endodontic sealer; AH, dentin impregnated with AH PLUS sealer; ES, EndoSequence BC Sealer; and MTA, MTA Fillapex. After cleaning, the persistence of residues and the number of open dentinal tubules were analyzed by scanning electron microscopy. Sixty bovine incisor crowns were divided into six groups (n=10): AH-SU, ES-SU, MTA-SU, AH-OU, ES-OU, and MTA-OU to evaluate the microshear bond strength in a universal testing machine and failure mode, in stereomicroscopy. Data were analyzed using the Kruskal-Wallis test, ANOVA, and post hoc Tukey tests (α=0.05).</p><p><strong>Results: </strong>AH Plus showed higher persistence of residues and fewer open tubules compared to other groups (<i>P</i><0.05), whereas EndoSequence BC Sealer and MTA Fillapex did not differ from each other (<i>P</i>>0.05). Bond strength was lower in AH Plus groups, regardless of the adhesive system used (<i>P</i><0.05). EndoSequence BC Sealer and MTA Fillapex exhibited similar and higher bond strength than AH Plus (<i>P</i>>0.05). Adhesive failure was the most frequent mode in all groups, except for MTA-SU, which showed a higher incidence of mixed failures.</p><p><strong>Conclusion: </strong>Residues of endodontic sealers affect dentinal penetrability and the adhesion of universal adhesives. In the present study, EndoSequence BC Sealer and MTA Fillapex had less impact on the adhesive interface than AH Plus, suggesting a lower impact on adhesion after cleaning with 95% ethanol.</p>","PeriodicalId":15599,"journal":{"name":"Journal of Dental Research, Dental Clinics, Dental Prospects","volume":"20 1","pages":"25-31"},"PeriodicalIF":0.0,"publicationDate":"2026-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13408623/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148620174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of Lip Pressure and Quality of Life Following Gummy Smile Treatment.","authors":"Paula Amaral Salgado Poliseli, Marcelo Palinkas, Nicole Barbosa Bettiol, Bianka Jurca Gonçalves da Motta, Paula Napolitano Gonçalves, Pedro Bastos Cruvinel, Selma Siéssere, Simone Cecilio Hallak Regalo","doi":"10.34172/joddd.44115","DOIUrl":"10.34172/joddd.44115","url":null,"abstract":"<p><strong>Introduction: </strong>A gummy smile is an aesthetic condition that can negatively impact self-esteem and quality of life. This longitudinal study aimed to evaluate the effects of gummy smile treatments with botulinum toxin type A and/or hyaluronic acid on lip pressure and the perceived quality of life in adult individuals.</p><p><strong>Methods: </strong>Thirty adult individuals aged 18‒65 years, with>2 mm of gingival exposure when smiling, participated in the study. They were randomly assigned to three groups: botulinum toxin (n=10), hyaluronic acid (n=10), and a combination of both (n=10). Lip pressure was measured using the Biofeedback Pró-Fono device at baseline and 15, 30, 90, and 180 days after the procedures. Quality of life was assessed using the Glasgow Benefit Inventory, which was applied 15 days after treatment. Statistical analyses included repeated-measures ANOVA with Bonferroni correction and t-tests (<i>P</i> ± 0.05).</p><p><strong>Results: </strong>All the groups showed variations in lip pressure over time, with a gradual increase up to 180 days and statistically significant differences. Intergroup comparisons across time intervals were not assessed. All three groups showed improvements in the quality of life, with the combined treatment standing out.</p><p><strong>Conclusion: </strong>Aesthetic treatments for gummy smile resulted in significant changes in lip pressure over time and were associated with improvements in the quality of life.</p>","PeriodicalId":15599,"journal":{"name":"Journal of Dental Research, Dental Clinics, Dental Prospects","volume":"20 1","pages":"43-49"},"PeriodicalIF":0.0,"publicationDate":"2026-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13402643/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148604074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Resin, Calcium Silicate, and Silicone-Based Root Canal Sealers on Postoperative Pain: A Randomized Controlled Clinical Trial.","authors":"Gizem Kadı, Esin Özlek","doi":"10.34172/joddd.42747","DOIUrl":"10.34172/joddd.42747","url":null,"abstract":"<p><strong>Introduction: </strong>This study aimed to compare the effects of resin- (AH Plus), calcium silicate- (iRoot SP), and silicone-based (GuttaFlow Bioseal) root canal sealers on postoperative pain.</p><p><strong>Methods: </strong>This study included 84 patients with mandibular molars diagnosed with irreversible pulpitis. Root canal shaping procedures were completed using X-Smart Plus (Dentsply Maillefer, Ballaigues, Switzerland) endodontic motor and EndoArt (İnci Dental, İstanbul, Turkey) nickel-titanium rotary system up to #25 (30.06) shaping file for mesial root anals and #30 (0.6) shaping file for root distal canals. The patients were randomly divided into 3 groups based on the root canal sealer used (n=28): group 1: AH Plus, group 2: iRoot SP, and group 3: GuttaFlow Bioseal. Pain scores were recorded using a visual analog scale (VAS) before and after treatment at the 6th, 24th, 48th, and 72nd hours, and at the first week. Additionally, the frequency and timing of analgesic intake were recorded. The chi-squared test was used for categorical variables. The Kruskal-Wallis test was used to compare differences in non-normally distributed continuous data between groups. The Friedman test was used to compare pain scores over time within each group, and the Cochran's Q test was used to analyze analgesic use.</p><p><strong>Results: </strong>No statistically significant differences in median VAS scores were found at various time intervals between the groups (<i>P</i>>0.05). Analgesic use distribution at the 6th (<i>P</i>=0.658) and the 24th (<i>P</i>=0.355) hours also did not show significant differences between the groups.</p><p><strong>Conclusion: </strong>Resin-, bioceramic-, or silicone-based sealers showed similar effects on postoperative pain.</p>","PeriodicalId":15599,"journal":{"name":"Journal of Dental Research, Dental Clinics, Dental Prospects","volume":"20 1","pages":"56-63"},"PeriodicalIF":0.0,"publicationDate":"2026-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13402645/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148603813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Histologic and Histomorphometric Analysis of the Effects of Bisphosphonate and Parathyroid Hormone with Bone Graft on Bone Healing and Formation in Rabbit Models.","authors":"Omid Soltaninia, Keyhan Soleimani, Fatemeh Mashhadi Abbas, Mohammadreza Khoshtarigh","doi":"10.34172/joddd.41940","DOIUrl":"10.34172/joddd.41940","url":null,"abstract":"<p><strong>Introduction: </strong>The standard method to accelerate healing of large bone defects involves using bone grafts alone or with biomaterials. Given the effects of bisphosphonates and parathyroid hormone (PTH) on bone remodeling, and the limited and contradictory studies available, this study aimed to evaluate the histologic and histomorphometric effects of combining bisphosphonate (zoledronic acid) and PTH (teriparatide) with bone grafts on bone healing and formation in rabbit models.</p><p><strong>Methods: </strong>Bilateral defects were created in the tibias 35 New Zealand white rabbits, divided into four groups, including negative control (no treatment) (n=5), positive control (bone powder) (n=10), intervention 1 (zoledronic acid+bone powder) (n=10), and intervention 2 (teriparatide+bone powder) (n=10). In each of the groups, half of the rabbits were euthanized in the 8th week and the other half in the 16th week after surgery, and their tibia bones were removed for histologic and histomorphometric evaluations. The outcomes were new bone formation, remaining bone graft percentage, foreign body reaction, and inflammation levels.</p><p><strong>Results: </strong>The highest percentage of new bone formation in the 8th week was observed in the intervention 2 group; in the 16th week, it was observed in the negative control group. However, the difference between the groups was not significant neither in the 8th week nor in the 16th week (<i>P</i>>0.05). The percentage of remaining bone graft in the intervention 1 group in the 8th and 16th week was significantly higher than in other groups (<i>P</i><0.05). In week 8, the amount of inflammation in the intervention 1 group was non-significantly higher than in the intervention 2 group (<i>P</i>>0.05), and in week 16, the amount of inflammation in the intervention group 1 was significantly higher than in the other two groups (<i>P</i><0.05). The highest frequency of foreign body reaction in the 8th and 16th weeks was related to the intervention 1 group (<i>P</i><0.05).</p><p><strong>Conclusion: </strong>Overall, teriparatide showed favorable outcomes. Teriparatide and bisphosphonate exhibited distinct and potentially complementary effects. Teriparatide promoted new bone formation and resorption, while bisphosphonates reduced bone graft resorption and caused inflammation and foreign body reactions. Further large-scale animal studies on teriparatide and bisphosphonate are recommended. These findings suggest time-dependent effects, with teriparatide potentially accelerating early healing and bisphosphonates prolonging graft persistence, though larger studies are necessary to confirm non-significant trends.</p>","PeriodicalId":15599,"journal":{"name":"Journal of Dental Research, Dental Clinics, Dental Prospects","volume":"20 1","pages":"10-17"},"PeriodicalIF":0.0,"publicationDate":"2026-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13402874/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148603828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unraveling The Link Between Stress and the Severity of Apical Periodontitis: A Systematic Review of Animal Studies.","authors":"Sıla Nur Usta, Antonio Magan-Fernandez, Cangül Keskin, Alper Ceylan, Francisco Mesa","doi":"10.34172/joddd.42826","DOIUrl":"10.34172/joddd.42826","url":null,"abstract":"<p><strong>Introduction: </strong>Apical periodontitis can occur due to the host immune response, with the release of antibodies, cytokines, and chemokines by stress as a systemic risk factor. This systematic review aimed to investigate the relationship between stress and the severity of apical periodontitis.</p><p><strong>Methods: </strong>A detailed search strategy was conducted on the \"PubMed (MEDLINE), Web of Science (all databases), Scopus, ScienceDirect, EMBASE, and Cochrane Library\" databases. Data were screened based on the eligibility criteria. Articles assessing the severity of apical periodontitis using different parameters in stress-induced animals in comparison with stress-free animals were selected. The risk of bias assessment was conducted using SYRCLE's RoB tool. The GRADEpro tool was used to determine the overall quality of evidence.</p><p><strong>Results: </strong>Four articles were selected after a full-text assessment. Animals under stress exhibited increased levels of inflammatory cells. The extension of the bone loss and the periapical lesion size differed according to the measurement and visualization methods. All the included articles had a high risk of bias. GRADEpro revealed that the overall certainty of evidence for the included studies was very low.</p><p><strong>Conclusion: </strong>Under the limitations of this systematic review, an increasing effect of stress on the inflammatory infiltrate was reported in apical periodontitis. Future well-conducted animal studies are warranted to further elaborate on the effects of stress parameters on the severity of apical periodontitis with convenient experimental conditions and advanced evaluation methods.</p>","PeriodicalId":15599,"journal":{"name":"Journal of Dental Research, Dental Clinics, Dental Prospects","volume":"20 1","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2026-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13408626/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148620242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association Between Calcium and Protein Content of Breast Milk and Severe Early Childhood Caries (S-ECC) in Toddlers.","authors":"Hamidreza Poureslami, Salehe Sabouri, Seerat Abbas Rajput, Milad Mollaali, Reyhaneh Aftabi, Parnian Poureslami, Abolfazl Shiri Varnamkhasti, Mohammad Reza Arabnezhad","doi":"10.34172/joddd.44503","DOIUrl":"10.34172/joddd.44503","url":null,"abstract":"<p><strong>Introduction: </strong>Severe early childhood caries (S-ECC) is a special type of dental decay common among toddlers and young children. This study explored the association between S-ECC and calcium and protein levels in mothers' breast milk in toddlers aged 12‒24 months.</p><p><strong>Methods: </strong>This cross-sectional descriptive-analytical study included 33 toddlers aged 12‒24 months, with or without S-ECC. Participants were recruited from mothers who brought their toddlers to healthcare clinics in Kerman City, Iran, for routine check-ups and vaccinations. The inclusion criteria for mothers were ages 18‒45 years during pregnancy and delivery at 37 weeks of gestation or later. Breast milk samples were obtained from the mothers of 17 toddlers with S-ECC and from the mothers of 16 toddlers with healthy teeth. The protein and calcium levels in the samples were measured using the Bradford assay and Flame Atomic Absorption Spectrophotometry assay, respectively.</p><p><strong>Results: </strong>The study found a significantly higher mean protein concentration but no significant difference in calcium concentration in breast milk from mothers whose children were caries-free compared with those whose children had caries. Also, the refined regression model predicted a significant inverse association between protein concentration and dental caries (OR=0.171). Additionally, boys exhibited 14.8 times greater odds of caries compared to girls (OR=14.818).</p><p><strong>Conclusion: </strong>It can be suggested that increased protein intake from breastfeeding in toddlers younger than 24 months, along with being female, is linked to a reduced risk of S-ECC.</p>","PeriodicalId":15599,"journal":{"name":"Journal of Dental Research, Dental Clinics, Dental Prospects","volume":"20 1","pages":"64-69"},"PeriodicalIF":0.0,"publicationDate":"2026-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13402664/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148604054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}