Journal of diabetes & metabolism最新文献

{"title":"Barriers to Patient Engagement in Managing Type 2 Diabetes Mellitus and How to Overcome It","authors":"A. Varma","doi":"10.35248/2155-6156.21.12.880","DOIUrl":"https://doi.org/10.35248/2155-6156.21.12.880","url":null,"abstract":"Phase Angle (PA) has been related to the integrity of cell membranes, as a good prognostic indicator, with the general health and nutritional status of patients. Hyperglycemia has already been shown to be a common outcome seen in patients with type 1 diabetes mellitus (TDM1) and is capable of causing glycotoxicity and cell damage if not regulated; mainly in the long term. A1C is currently considered the gold standard for assessing metabolic control in T1DM patients, as the relationship between their increased levels (>7%) which means blood glucose of 154 mg /dL or less) has been consistently demonstrated and the risk of chronic complications and adversities, and worsening prognosis in this population.","PeriodicalId":15597,"journal":{"name":"Journal of diabetes & metabolism","volume":"167 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81822454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Diabetic Retinopathy and Associated Risk Factors among Adult Diabetes Attending at Debre Tabor General Hospital, Northwest Ethiopia","authors":"Getasew Alemu Mersha, Yezinash Addis Alimaw, M. Tilahun, Tarkegn Cheklie Zeleke, A. Woredekal","doi":"10.35248/2155-6156.21.12.872","DOIUrl":"https://doi.org/10.35248/2155-6156.21.12.872","url":null,"abstract":"Aim: To assess the prevalence of diabetic retinopathy and its associated risk factors among adult diabetes at Debre Tabor General Hospital, Debre Tabor, Northwest, Ethiopia. Methodology: A cross sectional study was conducted at Debre Tabor General Hospital from June 29-August 28, 2020. A systematic random sampling technique was employed to select study participants. Interviewer based semistructured questioner, document review and physical examination were applied to collect the data. Labeling of diabetic retinopathy was done based on the Proposed International Clinical Diabetic Retinopathy and Severity Scale. Only the eye with the higher grade of retinopathy for each participant was included. Result: A total of 306 participants completed the study with a response rate of 97.7%. The median duration of diabetes was 4 (Range=7) years. The prevalence of diabetic retinopathy was 31.4% (95% Confidence Interval: 26.1%-36.3%). Low family monthly income (Adjusted Odds Ratio=7.4, 95% Confidence Interval 2.4-22.9), longer duration of diabetes (Adjusted Odds Ratio=27, 95% Confidence Interval 11.5-63.6) and poor glycemic control (Adjusted Odds Ratio=3.2, 95%Confidence Interval 1.5-6.7) were significantly associated with diabetic retinopathy. Conclusion and Recommendation: The prevalence of diabetic retinopathy washigh. Coordinated early screening of diabetic retinopathy in all adult diabetes was recommended.","PeriodicalId":15597,"journal":{"name":"Journal of diabetes & metabolism","volume":"6 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84795635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation between Glycated Haemoglobin Values and the Lipid Profile in Type 2 Diabetic Patients","authors":"N. GozifMohammed, H. MansourAbdulnabi, F. Al-Arabi, M. Madhukar","doi":"10.35248/2155-6156.21.12.885","DOIUrl":"https://doi.org/10.35248/2155-6156.21.12.885","url":null,"abstract":"Background: To investigate the relationship between glycated haemoglobin (HbA1c) and the lipid profile in patients of type-2 diabetes. Methods: The study has been conducted on 32 patients of type 2 diabetes. These are patients diagnosed with Type 2 diabetes of age group between 30 and 70 years. Blood samples were collected after 12 hours of fasting where blood samples were drawn before and after a meal from the patients to measure levels of the sugar and lipids. Various biochemical assays were carried out including fasting plasma glucose (FPG), PPBG, HbA1c and lipid profile, along with the patient’s age, and gender. The method that has been used for doing these investigations is Kit Spinreact. Results: The study found that the participants have an increase in FBG, PPBG, HbA1C, TC, TG, VLDL-C and LDL-C, with a decrease in HDL-C concentrations in type 2 diabetic patients. The result showed a correlation of HbA1c with other variables. The HbA1c significantly correlated with FBG (r=0.531, P=0.000), PPBG (r= 0.699, P=0.000), Total Cholesterol (r= 0.339, P=0.006), Triglycerides (r=0.357, P=0.004), Low-density Lipoprotein (r=0.269, P=0.031) and Very low-density Lipoprotein (r=0.364, P=0.003) where it was not correlated with HDL (r=-0.182, P=0.149). Conclusion: The HbA1c was significantly associated with all variables (lipid profile) except HDL which did not reach the significant level. These findings suggest that HbA1c level can be used as a good parameter for predicting the lipid profile of type 2 diabetic patients.","PeriodicalId":15597,"journal":{"name":"Journal of diabetes & metabolism","volume":"21 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73454576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of Diamelandreg; In the Treatment of Diabetic Foot Ulcers: A Randomized and Placebo-Controlled Phase II Clinical Trial","authors":"Marelys Yanes-Quesada, Daysi A. Navarro-Despaigne, E. Cabrera-Rode, J. J. Lence-Anta, Obdulio Gonzalez-Hern, Ez, Roberto Pena-Gener, E. Sanz-Navares","doi":"10.35248/2155-6156.21.12.891","DOIUrl":"https://doi.org/10.35248/2155-6156.21.12.891","url":null,"abstract":"Introduction: Diabetic foot ulcers are one of the most serious complications for patients with diabetes mellitus. The use of nutritional supplements such as Diamel® can be considered as an adjunct to conventional treatment in affected patients. Objective: To evaluate the effectiveness of the product Diamel® in the treatment of diabetic foot ulcers. Methods: Phase II double-blind, randomized, placebo-controlled clinical trial in a sample of 100 patients of both sexes with type 2 diabetes mellitus (DM) and with Wagner grade I-II-foot ulcers. All of them received conventional therapy, 50 of them combined with the product Diamel® and 50 combined with placebo. They followed up for a period of 1 year. The proportions of healed patients were taken as a response variable to determine efficacy. Other variables are analyzed: body mass index, glycemia, glycosylated hemoglobin, cholesterol, triglycerides, and creatinine, which were compared at the beginning and end of the study. Data analysis was performed according to the intention-to-treat principle. Results: The Diamel® group showed a 1-year cumulative healing rate of 89.2% (95% CI, 77.4-96.5) vs 72.4% (95% CI, 58.0-85.1) in the placebo group. The average healing time for ulcers in the Diamel® group was 3 months, significantly less than the Placebo group, which took 5 months, p=0.001. At the end of the study, HbA1c and fasting blood glucose had decreased significantly in the Diamel® group. Recurrence rates were lower in the Diamel® group (3 patients, 8%) than in the placebo group (8 patients, 16%), and no major adverse effects were reported in relation to the supplement. Conclusions: The Diamel® nutritional supplement showed a sufficient degree of efficacy in the treatment of diabetic foot ulcers in patients with type 2 DM, so large-scale studies should be undertaken.","PeriodicalId":15597,"journal":{"name":"Journal of diabetes & metabolism","volume":"36 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75247720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"International Congress and Expo on Endocrine and Diabetic Complications","authors":"W. Desalegn, S. Assegid, Mamo Nigatu","doi":"10.35248/2155-6156.21.12.878","DOIUrl":"https://doi.org/10.35248/2155-6156.21.12.878","url":null,"abstract":"Taking into consideration about current situation on COVID-19 Pandemic, Conference Series LLC Ltdwill be conducting a Webinar on “14th International Congress & Expo on Endocrine & Diabetic Complications” on November 09-10, 2020. The theme of the conference is “New recommendations and practical approaches in the treatment of endocrinal disorders and Management during COVID-19”. The webinar aims at providing a great scope for online interaction of Endocrinology Professionals, Diabetic Researchers, Academicians, industrialists, students and professors from around the globe on a single virtual platform.","PeriodicalId":15597,"journal":{"name":"Journal of diabetes & metabolism","volume":"67 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72643546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Magnitude of Hypertension and Associated Factors among Adult Diabetes Patients in Debre Tabor General Hospital, Debre Tabor, Northwest Ethiopia, 2019","authors":"W. Desalegn, S. Assegid, Mamo Nigatu","doi":"10.35248/2155-6156.21.12.886","DOIUrl":"https://doi.org/10.35248/2155-6156.21.12.886","url":null,"abstract":"Background: Despite being preventable disease, globally hypertension is among top ten leading causes of death. Hypertension, which is the most prevalent and independent cardiovascular risk factor in the general population, is extremely common problem in diabetics. To date there was no study done in Debre Tabor General Hospital to assess the magnitude of hypertension and associated factors among adult diabetics. Objective: assess the magnitude of hypertension and associated factors among adult diabetics in Debre Tabor General Hospital, Debre Tabor, Ethiopia, 2019. Methods: The study design was cross sectional and 228 diabetics were selected by systematic random sampling method. Face to face interview and observation techniques were used to collect data. Data were entered into Epi-data version 4.4.1 and exported to SPSS Version 20 for further analysis. Descriptive statistics was used to summarize data. A bivariate binary logistic regression model was used to select candidate variables for the final model. Multivariable binary logistic regression analysis was used to identify independently associated factors of hypertension among diabetes patients. An adjusted odd ratio was used to assess association between variables and 95% Confidence interval was used for statistical significance. Results: The overall prevalence of hypertension among diabetes clients in this study was 53.5% with 95% CI [47.7%- 60.2%].Urban [AOR=2.6(1.3-5.4)], having family history of hypertension[AOR=3.2(1.3-7.7)],suffering from overt diabetes for more than five years(AOR=7.5(2.7-21.4)], not controlled Fasting blood sugar [AOR=4.5(2.1-9.8)], not frequently consuming fruits[AOR=2.7(1.1-6.5)] not frequently consuming vegetables[AOR=7.9(3.6-17.2)]) frequently adding salt to food(AOR=3.8(1.1-13.8)] and body mass index(Kg/m2)≥25(AOR=2.9(1.4-6)] were independently associated with HTN. Conclusion and recommendation: The prevalence of hypertension among diabetes patients in this study was high (53.5%). Therefore it is better to design strategies for diabetes clients to lower their blood pressure in addition to anti-hypertensive medication and home to home blood pressure screening program for diabetic patients should be considered.","PeriodicalId":15597,"journal":{"name":"Journal of diabetes & metabolism","volume":"13 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80454324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endocrinology and Diabetology in the Present era of COVID-19","authors":"Igor Kelpikov","doi":"10.35248/2155-6156.21.12.879","DOIUrl":"https://doi.org/10.35248/2155-6156.21.12.879","url":null,"abstract":"Endocrinology Conference: It is our great pleasure to invite you to participate in the 12th Edition of webinar conference on Endocrinology & Diabetology which is an Online Webinar which will take place during 20-21 July 2020. The dedicated webinar theme is: Endocrine and metabolic link to corona virus infection. The purpose of the webinar is to bring together endocrinologists, diabetologists, Health Care Professionals and many experts to discuss the key note topics on Endocrinology & Diabetology. This meeting will enable exchange of ideas and knowledge between different disciplines for facilitating research and clinical interdisciplinary collaborations focusing on endocrinology. Let’s join hands for the future of this world, for the Next-gen of mankind, for the prospective and collective efforts to change what is within our reach and means. Our collaborative efforts have the power to change the destiny of those who are going to affected by this type of novel viruses look up to us, Endocrinologists, Pediatricians, Diabetologists, Gynecologists, all of us who deal with Endocrinology.","PeriodicalId":15597,"journal":{"name":"Journal of diabetes & metabolism","volume":"19 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86625904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Status of Glycemic Control and Associated Factors among Type 2 Diabetes Mellitus Patients in Northeast Ethiopia: A Cross-Sectional Study","authors":"Mitku Mammo Taderegew","doi":"10.35248/2155-6156.21.12.887","DOIUrl":"https://doi.org/10.35248/2155-6156.21.12.887","url":null,"abstract":"","PeriodicalId":15597,"journal":{"name":"Journal of diabetes & metabolism","volume":"26 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88146723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fasting Blood Sugar Levels and Associated Factors among Diabetes Patients in East Shewa, Ethiopia: Bayesian Approach","authors":"Biruk Shalmeno Tusa","doi":"10.35248/2155-6156.21.12.884","DOIUrl":"https://doi.org/10.35248/2155-6156.21.12.884","url":null,"abstract":"Introduction: Majority of diabetes patients fail to achieve adequate level of fasting blood sugar. Therefore, the pre Department of Epidemiology & Biostatistics, Collage of Health and Medical Sciences, Haramaya University, Haramaya, Ethiopia sent study uses a Bayesian framework to identify factors associated with level of fasting blood sugar. Methods: Institution based cross-sectional study was employed. Markov chain Monte Carlo (MCMC) simulation was used to estimate the model parameters. Summary statistic including mean, standard deviation (SD) and 95% credible intervals (CI) of unknown parameters was calculated from stored MCMC samples. Result: The mean (±SD) fasting blood sugar level was 151.07 (±38.21) mg/dl. Good Diabetic self-care activities (β=-8.78; HPD CI: (-16.63, -0.93)), having chronic illness other than diabetes mellitus (DM) (β=9.89; HPD CI: (1.39- 18.38)), taking insulin (β=16.82; HPD CI: (4.82, 28.83)) and both insulin and oral anti-diabetic medication (β=32.31; HPD CI: (15.20, 49.37)) and having serious psychological distress (β=15.46; HPD CI: (1.70 – 29.17)) were significantly associated with level of fasting blood sugar. Conclusions: Diabetic self-care activities, chronic illness other than DM, treatment regimen and depression were strong predictors of fasting blood sugar level among DM patients. Therefore, we recommend that integration of screening & treating for depression & comorbidities and give counseling on diabetic self-care activity along with the already existing DM treatment.","PeriodicalId":15597,"journal":{"name":"Journal of diabetes & metabolism","volume":"1119 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76786947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intelligence Based Diabetes Management System","authors":"Anchana P Belmon, J. Auxillia","doi":"10.35248/2155-6156.21.12.897","DOIUrl":"https://doi.org/10.35248/2155-6156.21.12.897","url":null,"abstract":"The use of continuous glucose sensors are currently trending in type 1 diabetes patients which provides enormous forthcoming adverse effects like hyperglycemia and hypoglycemia. The development of diabetes management system automatically collect sensor information and make correct recommendations to patients. The incorporation of Artificial Intelligence sensors supports glucose prediction in diabetes patients with fine tuning of bolus calculation and parameters.","PeriodicalId":15597,"journal":{"name":"Journal of diabetes & metabolism","volume":"28 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85007234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}