Journal of Cytology and Histology最新文献_第9页

Three Cases of Major Depression: Different Pharmacological Antidepressant Options 三例重度抑郁症:不同的抗抑郁药物选择

Journal of Cytology and Histology Pub Date : 2017-06-28 DOI: 10.4172/2157-7099.1000457

F. Werner, R. Coveñas

{"title":"Three Cases of Major Depression: Different Pharmacological Antidepressant Options","authors":"F. Werner, R. Coveñas","doi":"10.4172/2157-7099.1000457","DOIUrl":"https://doi.org/10.4172/2157-7099.1000457","url":null,"abstract":"Three cases with different forms of major depression and different pharmacological antidepressant treatments are presented. In the first case report, citalopram, a selective serotonin reuptake inhibitor, improved transient depressive symptoms in a professionally busy man who recovers from the depressive symptoms and solves the social problems in his team. In the second case report showing a severe form of major depression and a suicide attempt, the tricyclic antidepressant drug doxepin failed to improve depressive symptoms. The selective serotonin and noradrenaline reuptake inhibitor venlafaxine partly improved depressive symptoms. Lithium carbonate, a prophylactic drug, which shows antidepressant and antimanic effects, treated depressive symptoms successfully. The cardiac and renal adverse effects were controlled. In the third case report, citalopram was used to treat the chronic form of major depression; however the adverse effects such as sedating and drive-reducing effects and the weight gain were disturbing for the patient. The administration of the selective dopamine and noradrenaline reuptake inhibitor bupropion ameliorated depressive symptoms and sleepiness, however caused hypertension and insomnia. Due to this changed medication, the patient succeeded in coping with a stressful life event, an anti-cancer therapy.","PeriodicalId":15528,"journal":{"name":"Journal of Cytology and Histology","volume":"28 10","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2017-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72568208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The impact of extensive cytoreductive surgery for ovarian cancer on the histopathology laboratory workload 广泛的卵巢癌细胞减少手术对组织病理学实验室工作量的影响

Journal of Cytology and Histology Pub Date : 2017-06-28 DOI: 10.4172/2157-7099.1000454

A. El-Masry, M. El-Bahrawy

{"title":"The impact of extensive cytoreductive surgery for ovarian cancer on the histopathology laboratory workload","authors":"A. El-Masry, M. El-Bahrawy","doi":"10.4172/2157-7099.1000454","DOIUrl":"https://doi.org/10.4172/2157-7099.1000454","url":null,"abstract":"Objectives: Cytoreductive surgery is the principal management for ovarian cancer. Recently there has been progressive change to more extensive cytoreductive surgery (ECS) as evidence shows this improves patient prognosis. The aim of this study is to investigate the change in histopathology work load with change in surgical practice for the treatment of ovarian cancer patients at Hammersmith Hospital, UK. Materials and methods: Specimens for patients with ovarian cancer (n=116) were selected and classified into three groups: (i) standard debulking surgery; (ii) a mix of standard debulking and ECS and (iii) ECS only. The types of specimens and numbers of blocks in each group were studied. Results: Post-hoc analysis demonstrates a statistically significant increase in the number of specimens per case from standard debulking to the mixed group (p<0.0001) and to the ECS group (p<0.0001). There is also a statistically significant increase in the number of blocks from standard debulking to the mixed (p<0.0001) and to the ECS groups (p<0.0001). Conclusion: The study shows there is a significant increase in the histopathology workload with the shift from standard to extensive cytoreductive surgery, as well as increase in the complexity and range of specimens sent for histopathological examination. It is essential that centres opting for a shift to ECS ensure that adequate provisions and resources are in place to accommodate these changes.","PeriodicalId":15528,"journal":{"name":"Journal of Cytology and Histology","volume":"16 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2017-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82122958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The Role of Combined Nicotine and Caffeine Administration on theHistological Structure of the Rat Urinary Bladder with a Special Referenceto P53 尼古丁和咖啡因联合给药对大鼠膀胱组织结构的作用，特别涉及P53

Journal of Cytology and Histology Pub Date : 2017-06-28 DOI: 10.4172/2157-7099.1000455

Alhan I Allehaibi, S. K. Abunasef, A. I. Zaki

{"title":"The Role of Combined Nicotine and Caffeine Administration on theHistological Structure of the Rat Urinary Bladder with a Special Referenceto P53","authors":"Alhan I Allehaibi, S. K. Abunasef, A. I. Zaki","doi":"10.4172/2157-7099.1000455","DOIUrl":"https://doi.org/10.4172/2157-7099.1000455","url":null,"abstract":"Background: It is difficult to find microscopic studies that can demonstrate the effect of combined administration of nicotine and caffeine on the mucosa of the rat urinary bladder. Aim of work: So, the current study aimed at demonstration of histological and p53 immuno-histochemical expression of the mucosa of rat urinary bladder as a marker sharing in process of apoptosis following the combined administration of nicotine and caffeine. Materials and methods: The animals were divided randomly into 4 groups: control, Nicotine, caffeine and combined Nicotine and Caffeine. The urinary bladder was processed and stained with hematoxylin and eosin stain, histochemically by PAS and immunohistochemically by Anti p53 antibodies. Results: After nicotine there was apparent increase in the layers of epithelium with intraepithelial lymphocytes. The strong PAS positive reaction of the basal layer together with P53 positive expression of few lamina propria cells was evident. After caffeine, the epithelial layers and mononuclear cells of the lamina propria were increased. There was a marked decrease in the PAS positive reacting cells of the superficial cell layer. The groups that have administered combine caffeine and nicotine; there were focal areas of epithelial erosion with proliferating basal layers. There was a strong PAS positive reaction under the basal layer and p53 positive expression of many lamina propria cells. Conclusion: The present study had concluded that the chronic administration of combined nicotine and caffeine could result in epithelial hyperplasia associated with positive P53 expression in nuclei of lamina propria cells of the urinary bladder mucosa.","PeriodicalId":15528,"journal":{"name":"Journal of Cytology and Histology","volume":"91 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2017-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74071065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Shall we Sample Every Pancreatic Mass 我们要对每个胰腺肿块取样吗

Journal of Cytology and Histology Pub Date : 2017-06-20 DOI: 10.4172/2157-7099.1000453

J. Frossard

引用次数: 1

Percutaneous Injection of Polymethyl Methacrylate for the Treatment ofOsteoarthritic Knee Pain Caused by Bone Marrow Edema: A Case Reportand Review of Literature 经皮注射聚甲基丙烯酸甲酯治疗骨髓水肿所致骨关节炎性膝关节疼痛1例并文献复习

Journal of Cytology and Histology Pub Date : 2017-06-15 DOI: 10.4172/2157-7099.1000452

Lihua Gao, Guiqiang Miao, Xuehui Zang, Hui Sun, Lihui Wang

引用次数: 1

Bone Marrow Derived Mesenchymal Stem Cell Therapy in Induced Acute Renal Injury in Adult Male Albino Rats 骨髓间充质干细胞治疗成年雄性白化大鼠急性肾损伤

Journal of Cytology and Histology Pub Date : 2017-05-15 DOI: 10.4172/2157-7099.1000451

Abdullaev Sa, A. Husseinali, A. SayedMahmoud, A. FathyAhmed, R. Soliman

{"title":"Bone Marrow Derived Mesenchymal Stem Cell Therapy in Induced Acute Renal Injury in Adult Male Albino Rats","authors":"Abdullaev Sa, A. Husseinali, A. SayedMahmoud, A. FathyAhmed, R. Soliman","doi":"10.4172/2157-7099.1000451","DOIUrl":"https://doi.org/10.4172/2157-7099.1000451","url":null,"abstract":"Background and objectives: Acute renal injury (ARI) is a serious clinical problem without established regimen for treatment. Mesenchymal stem cells (MSCs) are undifferentiated cells that can differentiate and give rise to other cell types. The aim of the present work is to study the possible therapeutic role of MSCs in the treatment of the deleterious changes occurred in renal cortex and medulla of adult male albino rat model of ischemia/reperfusion (I/R) ARI. Material and methods: Forty adult male albino rats were used in this study. Animals were divided into four groups, 10 animals for each group. Group I is control sham-operated group. Three experimental groups were all subjected to I/R injury by clamping both renal pedicles for 40 min. These animals were further divided into three subgroups. Group II is non-MSC treated group. Group III (MSC treated group (local injection)): I/R animals received bromodeoxyuridine labeled BM-MSCs locally in renal cortex immediately after removal of the clamps and confirmation of reflow. Group IV (MSC treated group (systemic injection)): I/R animals that received single intravenous injection of bromdeoxyouridine labeled BM-MSCs in tail vein immediately after removal of the clamps and confirmation of reflow. Animals were sacrificed after 3 days of intervention. Serological measurements included serum urea and creatinine. Kidney specimens were processed for H&E, PCNA and Caspase-3. Real time RT-PCR study was done for TNF α and IL-6 gene expression. Results: Cortical and medullary renal tissue exhibited marked improvement histologically and serologically after MSCs treatment. The improvement was more obvious in case of systemic treatment. Conclusion: The present study shows the ability of MSCs to repair the structural and functional renal damage after I/R, Systemic route is more beneficial than local route. This may pave the future for therapeutic use of MSCs in the treatment of acute renal injury.","PeriodicalId":15528,"journal":{"name":"Journal of Cytology and Histology","volume":"9 1","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2017-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79552372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Spermatocyte Spreading during Meiotic Cell Preparation is a Two StepProcess 减数分裂细胞制备过程中精母细胞的扩散是一个两步走的过程

Journal of Cytology and Histology Pub Date : 2017-04-26 DOI: 10.4172/2157-7099.1000450

Razan Muhtadi, E. Ahmed, H. Scherthan

引用次数: 4

Primary Vaginal Invasive Squamous Cell Carcinoma: A Rare Case Report 原发性阴道浸润性鳞状细胞癌1例报告

Journal of Cytology and Histology Pub Date : 2017-04-26 DOI: 10.4172/2157-7099.1000449

T. Santosh, Pramita Sahu, M. Patro, Anshuman Mishra

引用次数: 1

Inflammatory Pseudotumor of the Spleen: A Case Report 脾炎性假瘤1例

Journal of Cytology and Histology Pub Date : 2017-04-26 DOI: 10.4172/2157-7099.1000448

K. An

引用次数: 0

Laparoscopic Hysterectomy with Anterior Four-Arm Mesh ImplantTechnique in the Surgical Treatment of a Woman with Pelvic OrganProlapse and Urinary Incontinence: A Case Report and Review of theLiterature 腹腔镜子宫切除术联合前路四臂网片植入技术治疗女性盆腔器官脱垂和尿失禁1例报告及文献复习

Journal of Cytology and Histology Pub Date : 2017-03-27 DOI: 10.4172/2157-7099.1000446

G. Sukgen

{"title":"Laparoscopic Hysterectomy with Anterior Four-Arm Mesh ImplantTechnique in the Surgical Treatment of a Woman with Pelvic OrganProlapse and Urinary Incontinence: A Case Report and Review of theLiterature","authors":"G. Sukgen","doi":"10.4172/2157-7099.1000446","DOIUrl":"https://doi.org/10.4172/2157-7099.1000446","url":null,"abstract":"Abstract Purpose: A woman with Pelvic Organ Prolapse (POP) and Stres Urinary A°ncontinence (SUI) who was treated with a technique utilizing laparoscopic hysterectomy followed by the placement of a 4-arm polypropylene mesh. Methods: Patient who applied to the clinic due to recurrent postmenopausal bleeding, urinary incontinence and vaginal swelling was performed alternative laparoscopic hysterectomy due to such factors as previous recurrent pelvic surgery, lack of isolated uterine descensus, and difficulty of vaginal hysterectomy. In the same session, the patient was treated with anterior 4-arms POP mesh implant. Results: Post-operative 6 months follow ups, both functional and anatomical improvement were observed as the patient’s SUI became continence, and there was an improvement in POP. Conclusion: The combination of laparoscopic hysterectomy, POP 4-arm mesh implant and anti-incontinence surgery in the hysterectomy plan is functional and effective for bbenign reasons in patients with POP and SUI. Future studies are needed to evaluate the utility of this technique","PeriodicalId":15528,"journal":{"name":"Journal of Cytology and Histology","volume":"5 1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81213058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0