Jean C.O. Menegatt , Claiton I. Schwertz , Vânia S. Bourckhardt , Roberta T.B. França , Fernanda F. Perosa , Manoela M. Piva , Brenda O. Silveira , David Driemeier
{"title":"Polyserositis, meningoencephalitis, arthritis and omphalitis due to Salmonella Agona infection in a pig","authors":"Jean C.O. Menegatt , Claiton I. Schwertz , Vânia S. Bourckhardt , Roberta T.B. França , Fernanda F. Perosa , Manoela M. Piva , Brenda O. Silveira , David Driemeier","doi":"10.1016/j.jcpa.2025.12.002","DOIUrl":"10.1016/j.jcpa.2025.12.002","url":null,"abstract":"<div><div>Bacterial polyserositis, arthritis and meningitis are well-known conditions in pigs, commonly linked to <em>Glaesserella parasuis</em>, <em>Streptococcus suis</em> and <em>Mycoplasma hyorhinis</em>. <em>Salmonella enterica</em> infections, particularly <em>S.</em> Typhimurium and <em>S.</em> Choleraesuis, typically present as enteric or septicaemic diseases. This study reports a rare case of <em>Salmonella enterica</em> subsp. <em>enterica</em> serovar Agona (<em>S.</em> Agona) infection in an 80-day-old pig presenting with polyserositis, meningoencephalitis, arthritis and omphalitis. In the bacteriological examination, a pure culture of <em>S</em><em>.</em> Agona was obtained from the fibrinous lesions, which enabled diagnosis. Additionally, immunohistochemical examination allowed confirmation of the septicaemic distribution of the bacteria. The findings suggest umbilical contamination as the probable infection route, differing from the usual fecal-oral transmission of <em>Salmonella</em>. Although non-enteric <em>Salmonella</em> infections have been documented in various species, this is the first confirmed case of <em>S.</em> Agona causing such lesions in pigs. This case highlights the importance of specific diagnostic approaches to accurately identify the aetiological agent, as clinical and pathological presentations may resemble other common bacterial infections in pigs.</div></div>","PeriodicalId":15520,"journal":{"name":"Journal of Comparative Pathology","volume":"223 ","pages":"Pages 1-4"},"PeriodicalIF":0.9,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145847625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luise K. Jubrael , Angélica Consalter , Tábata Maués , Cátia D. de Paula , Geovanni D. Cassali , Maria de Lourdes G. Ferreira
{"title":"First report of malignant adenomyoepithelioma in a guinea pig (Cavia porcellus)","authors":"Luise K. Jubrael , Angélica Consalter , Tábata Maués , Cátia D. de Paula , Geovanni D. Cassali , Maria de Lourdes G. Ferreira","doi":"10.1016/j.jcpa.2025.11.004","DOIUrl":"10.1016/j.jcpa.2025.11.004","url":null,"abstract":"<div><div>Mammary cancer is one of the most common neoplasms in women and female dogs, and it has also been found to occur with significant frequency in guinea pigs (<em>Cavia porcellus</em>). A 4-year-old female guinea pig presented with a firm, irregular shaped mass, measuring 6.6 cm in the largest axis, in the right mammary gland. Cytological examination suggested mammary carcinoma. Based on these results, a right inguinal mammectomy was performed. Histological examination revealed a biphasic neoplastic proliferation in the hypodermis consisting of epithelial cells in cribriform, papillary, tubule and nest arrangements, and malignant myoepithelial cells arranged in multidirectional bundles and nests, with marked anisocytosis and anisokaryosis. Immunolabelling was positive for GATA3 and Ckpan in the epithelial component and positive for p63 in the myoepithelial component. After 71 days, the patient developed severe dyspnoea and agitation, and chest radiography showed several rounded structures distributed multifocally throughout the lung parenchyma, the largest of them measuring 0.9 × 0.6 cm. Macroscopic and histological examinations revealed multifocal metastases in the lung parenchyma, multifocal suppurative pneumonia and severe diffuse pulmonary oedema, confirming the cause of death as respiratory failure due to lung metastases. A metastatic malignant adenomyoepithelioma was diagnosed on the basis of the macroscopic, histological and immunohistochemical findings.</div></div>","PeriodicalId":15520,"journal":{"name":"Journal of Comparative Pathology","volume":"223 ","pages":"Pages 13-16"},"PeriodicalIF":0.9,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145922979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alexandra Guillén , Kara Kropp , Francesco Rogato , Andrew D. Yale , Gabriella Hetesy , Jérémy Béguin , Kerstin Erles , Simon L. Priestnall , Edouard Reyes-Gomez , Alexandros Hardas
{"title":"Corrigendum to “Evaluation of tumour biomarkers associated with invasion, metastasis and immune escape in cats with exocrine pancreatic carcinoma” [J Comp Pathol 220 (2025) 2812]","authors":"Alexandra Guillén , Kara Kropp , Francesco Rogato , Andrew D. Yale , Gabriella Hetesy , Jérémy Béguin , Kerstin Erles , Simon L. Priestnall , Edouard Reyes-Gomez , Alexandros Hardas","doi":"10.1016/j.jcpa.2025.07.011","DOIUrl":"10.1016/j.jcpa.2025.07.011","url":null,"abstract":"","PeriodicalId":15520,"journal":{"name":"Journal of Comparative Pathology","volume":"222 ","pages":"Pages 1-2"},"PeriodicalIF":0.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144853024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assessment of nuclei density in a porcine wound model by application of InstanSeg","authors":"K. Barington , H. Jensen","doi":"10.1016/j.jcpa.2025.10.025","DOIUrl":"10.1016/j.jcpa.2025.10.025","url":null,"abstract":"","PeriodicalId":15520,"journal":{"name":"Journal of Comparative Pathology","volume":"222 ","pages":"Page 35"},"PeriodicalIF":0.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145620677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Romanello , A. Levov , P. Roccabianca , L. Ressel
{"title":"“Lymphom-AI”: A preliminary application of deep learning for lymph nodes and canine lymphoma classification","authors":"C. Romanello , A. Levov , P. Roccabianca , L. Ressel","doi":"10.1016/j.jcpa.2025.10.013","DOIUrl":"10.1016/j.jcpa.2025.10.013","url":null,"abstract":"","PeriodicalId":15520,"journal":{"name":"Journal of Comparative Pathology","volume":"222 ","pages":"Page 31"},"PeriodicalIF":0.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145620699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}