Journal of Comparative Pathology最新文献

Revisiting canine proliferative sparganosis: Implications for diagnosis, taxonomy and zoonotic surveillance 重访犬增殖性斯巴达病：诊断、分类和人畜共患病监测的意义

IF 0.9 4区农林科学

Journal of Comparative Pathology Pub Date : 2025-09-27 DOI: 10.1016/j.jcpa.2025.09.001

Nathkapach K. Rattanapitoon , Patpicha Arunsan , Nav La , Schawanya K. Rattanapitoon

引用次数: 0

Multiple congenital pulmonary malformations in a black-capped Bolivian squirrel monkey (Saimiri boliviensis boliviensis) 一只黑冠玻利维亚松鼠猴的多重先天性肺畸形

IF 0.9 4区农林科学

Journal of Comparative Pathology Pub Date : 2025-08-19 DOI: 10.1016/j.jcpa.2025.08.001

Mayane Faccin, Sarah M. Kezar

引用次数: 0

Corrigendum to “Evaluation of tumour biomarkers associated with invasion, metastasis and immune escape in cats with exocrine pancreatic carcinoma” [J Comp Pathol 220 (2025) 2812] “外分泌型胰腺癌的侵袭、转移和免疫逃逸相关肿瘤生物标志物的评价”[J] .中国病理杂志，2002,28(4):327 - 327。

IF 0.9 4区农林科学

Journal of Comparative Pathology Pub Date : 2025-08-15 DOI: 10.1016/j.jcpa.2025.07.011

Alexandra Guillén , Kara Kropp , Francesco Rogato , Andrew D. Yale , Gabriella Hetesy , Jérémy Béguin , Kerstin Erles , Simon L. Priestnall , Edouard Reyes-Gomez , Alexandros Hardas

引用次数: 0

Chondrosarcoma in a captive giant anteater (Myrmecophaga tridactyla) 一只圈养巨食蚁兽（食蚁兽）的软骨肉瘤

IF 0.9 4区农林科学

Journal of Comparative Pathology Pub Date : 2025-08-01 DOI: 10.1016/j.jcpa.2025.08.002

Gustavo W. Pandolfo , Jéssica A. Withoeft , Aline R. Baron , Anna L. de Oliveira Cunha , João V.C. Roeder , Daniel Fedullo , Renata A. Casagrande

{"title":"Chondrosarcoma in a captive giant anteater (Myrmecophaga tridactyla)","authors":"Gustavo W. Pandolfo , Jéssica A. Withoeft , Aline R. Baron , Anna L. de Oliveira Cunha , João V.C. Roeder , Daniel Fedullo , Renata A. Casagrande","doi":"10.1016/j.jcpa.2025.08.002","DOIUrl":"10.1016/j.jcpa.2025.08.002","url":null,"abstract":"<div><div>The development of neoplasms in giant anteaters (<em>Myrmecophaga tridactyla</em>) is poorly documented, with most studies focused on non-neoplastic changes. This report describes a case of chondrosarcoma in a 15-year-old male captive giant anteater that presented with lameness for approximately 6 months, locomotion difficulties and swelling of the left thoracic limb. After review of a radiograph, humane euthanasia was decided due to the poor prognosis and quality of life. At necropsy, a 17 × 20 × 13 cm mass was seen to project from the humeroradioulnar joint of the left thoracic limb. The mass was white, firm to soft, with translucent areas and moderate multifocal irregular cavitations. Histologically, it consisted of a poorly demarcated and partially encapsulated malignant mesenchymal neoplasm, arranged in irregular lobules of varying sizes containing hyaline cartilage. Immunohistochemical analysis revealed moderate immunolabelling of vimentin in neoplastic mesenchymal cells but no immunolabelling for pan cytokeratin. Based on the macroscopic, histopathological and immunohistochemical findings, a diagnosis of chondrosarcoma was established. This case emphasizes the importance of diagnosing diseases in captive species in which pathological conditions are rarely documented. This appears to be the first reported case of chondrosarcoma in a giant anteater.</div></div>","PeriodicalId":15520,"journal":{"name":"Journal of Comparative Pathology","volume":"221 ","pages":"Pages 50-53"},"PeriodicalIF":0.9,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144829091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Complex developmental cardiovascular anomalies in a Sahiwal calf: a case study on patent ductus arteriosus, defective interatrial septum and arterial malformations Sahiwal小牛复杂的发育性心血管异常：动脉导管未闭、房间隔缺损和动脉畸形的个案研究

IF 0.9 4区农林科学

Journal of Comparative Pathology Pub Date : 2025-08-01 DOI: 10.1016/j.jcpa.2025.07.006

Ersavadla Rajaraviteja , Poovathikkal Suvaneeth , Paramadayalan S. Selvan , Ramaswamy V. Prasad

{"title":"Complex developmental cardiovascular anomalies in a Sahiwal calf: a case study on patent ductus arteriosus, defective interatrial septum and arterial malformations","authors":"Ersavadla Rajaraviteja , Poovathikkal Suvaneeth , Paramadayalan S. Selvan , Ramaswamy V. Prasad","doi":"10.1016/j.jcpa.2025.07.006","DOIUrl":"10.1016/j.jcpa.2025.07.006","url":null,"abstract":"<div><div>We document complex developmental anomalies of the cardiovascular system, including patent ductus arteriosus (PDA), additional pulmonary arteries, malformed interatrial septum (IAS), unconventional origin of the common brachiocephalic trunk (CBCT) and subclavian arteries, in a 1-week-old calf of the Indian Sahiwal breed. The PDA was comprised of a cylindrical tube of regular calibre. Additional pulmonary arteries originated from the pulmonary trunk immediately after the bifurcation into the pulmonary arteries. The IAS had the form of an inverted cone frustrum, which projected towards the left atrial chamber, with a wider opening towards the right atrium and a narrow opening towards the left atrium, and contained blood clots. The CBCT originated from the systemic aorta, with the right subclavian artery emerging as its first branch. Microscopic observation revealed that the PDA appeared similar to other blood vessels but with an uneven wall, resulting from a predominant smooth muscle cell population. The PDA had fewer internal cushions and less elasticity, suggesting a lower chance of conversion to the ligamentum arteriosum.</div></div>","PeriodicalId":15520,"journal":{"name":"Journal of Comparative Pathology","volume":"221 ","pages":"Pages 40-44"},"PeriodicalIF":0.9,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144748619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rare case of association of mesenteric volvulus and left hepatic hypoplasia in a German Shepherd Dog 德国牧羊犬肠系膜扭转合并左肝发育不全的罕见病例

IF 0.9 4区农林科学

Journal of Comparative Pathology Pub Date : 2025-08-01 DOI: 10.1016/j.jcpa.2025.07.007

Caio A. Diamantino , Tatyana S. de Carvalho , Felipe M. Pastor , Moacir Carretta-Júnior , Rodrigo O.S. Silva , Natália de M. Ocarino , Rogéria Serakides

{"title":"Rare case of association of mesenteric volvulus and left hepatic hypoplasia in a German Shepherd Dog","authors":"Caio A. Diamantino , Tatyana S. de Carvalho , Felipe M. Pastor , Moacir Carretta-Júnior , Rodrigo O.S. Silva , Natália de M. Ocarino , Rogéria Serakides","doi":"10.1016/j.jcpa.2025.07.007","DOIUrl":"10.1016/j.jcpa.2025.07.007","url":null,"abstract":"<div><div>We report a rare case of association of mesenteric volvulus and left hepatic hypoplasia in an approximately 6-year-old, uncastrated male German Shepherd Dog. The small and large intestines were displaced from their normal anatomical position and intensely dilated, with diffusely hyperaemic and haemorrhagic serosae. The mesenteric root, at its insertion into the roof of the abdominal cavity, was twisted 360° counterclockwise along its axis. The small and large intestines had thick, haemorrhagic and oedematous walls, with liquefied, bloody and fetid contents throughout. The left medial and lateral hepatic lobes and the caudate process of the caudate lobe were markedly reduced in size, while the right medial lobe was slightly enlarged, indicating left hepatic hypoplasia with mild compensatory right-sided hypertrophy. Intestinal samples tested negative for <em>Clostridioides difficile</em>, <em>Salmonella</em> spp, canine parvovirus, <em>Giardia</em> spp and <em>Campylobacter</em> spp. Microscopic analysis revealed diffuse necrosis of the mucosa and marked diffuse haemorrhage in the intestines, with preservation of crypts. In the lamina propria, a mild lymphoplasmacytic infiltrate was present, along with some intact and degenerated neutrophils. The only histological difference observed between the hypoplastic and normal hepatic lobes was moderate biliary hyperplasia and hypertrophy. Based on the macroscopic findings, the diagnosis of mesenteric volvulus and left hepatic hypoplasia was confirmed, both of which are considered rare in dogs. The severity of the hepatic hypoplasia may have predisposed to mesenteric volvulus.</div></div>","PeriodicalId":15520,"journal":{"name":"Journal of Comparative Pathology","volume":"221 ","pages":"Pages 45-49"},"PeriodicalIF":0.9,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144770522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Beak neoplasia in avian species: description of nine cases 鸟类喙部瘤变：附9例报告

IF 0.9 4区农林科学

Journal of Comparative Pathology Pub Date : 2025-08-01 DOI: 10.1016/j.jcpa.2025.07.010

Daniel F. Barrantes Murillo , Alexis Berrocal , Lauren W. Stranahan , Emily J. Brinker , Linden E. Craig , Tatiane T. Negrão Watanabe

{"title":"Beak neoplasia in avian species: description of nine cases","authors":"Daniel F. Barrantes Murillo , Alexis Berrocal , Lauren W. Stranahan , Emily J. Brinker , Linden E. Craig , Tatiane T. Negrão Watanabe","doi":"10.1016/j.jcpa.2025.07.010","DOIUrl":"10.1016/j.jcpa.2025.07.010","url":null,"abstract":"<div><div>Beak neoplasia is a rare condition in avian species and is most often reported within the order Psittaciformes. Through a multi-institutional retrospective study, we describe nine cases of beak neoplasia from six species belonging to the orders Galliformes (<em>Gallus gallus domesticus</em> and <em>Syrmaticus reevesii</em>), Psittaciformes (<em>Amazona</em> sp and <em>Ara</em> sp), Anseriformes (<em>Anas platyrhynchos domesticus</em>) and Columbiformes (<em>Columbina livia domestica</em>). The sex distribution was four females, four males and one not specified. The average age at the time of diagnosis was 11.8 years (range 2–38 years; standard deviation ± 12.8 years). The most commonly reported tumour was squamous cell carcinoma, followed by melanoma; metastases were documented in both neoplasms. Other diagnosed neoplasms included undifferentiated carcinoma, lipoma and fibrosarcoma. Most neoplasms were located at the maxillary rhamphotheca (66 %; 6/9). Clinical signs included chronic weight loss, anorexia, hyporexia, inappetence, dysphagia, extensive ulceration of the beak keratin, secondary bacterial infection, halitosis, crop impaction and dyspnoea. The progression of neoplasms affecting the beak varied from 3 weeks to several years, leading to euthanasia in 55 % (5/9) of the cases.</div></div>","PeriodicalId":15520,"journal":{"name":"Journal of Comparative Pathology","volume":"221 ","pages":"Pages 35-39"},"PeriodicalIF":0.9,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144748693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Epidermal growth factor-containing fibulin-like extracellular matrix 1-derived amyloidosis with fatal gastric bleeding in a Tsushima leopard cat (Prionailurus bengalensis euptilurus) 含表皮生长因子的纤维蛋白样细胞外基质1源性淀粉样变性伴致死性胃出血1例对马豹（Prionailurus bengalensis euptilurus）

IF 0.9 4区农林科学

Journal of Comparative Pathology Pub Date : 2025-07-29 DOI: 10.1016/j.jcpa.2025.07.009

Hiroto Fukui , Natsumi Kobayashi , Tomoaki Murakami , Shin-ichi Nakamura , Sho Kadekaru , Yumi Une

{"title":"Epidermal growth factor-containing fibulin-like extracellular matrix 1-derived amyloidosis with fatal gastric bleeding in a Tsushima leopard cat (Prionailurus bengalensis euptilurus)","authors":"Hiroto Fukui , Natsumi Kobayashi , Tomoaki Murakami , Shin-ichi Nakamura , Sho Kadekaru , Yumi Une","doi":"10.1016/j.jcpa.2025.07.009","DOIUrl":"10.1016/j.jcpa.2025.07.009","url":null,"abstract":"<div><div>Epidermal growth factor-containing fibulin-like extracellular matrix 1 (EFEMP1)-derived amyloidosis causes gastrointestinal bleeding in humans. Amyloidosis has also been reported in the Tsushima leopard cat (<em>Prionailurus bengalensis euptilurus</em>) and rhesus macaque (<em>Macaca mulatta</em>). However, the clinical signs and lesions in humans and animals differ. A captive Tsushima leopard cat, aged 19 years, died of haemorrhage due to a gastric ulcer and a pathological analysis was performed. Amyloid was deposited in the venous walls and interstitium of the systemic organs, especially the stomach and intestines. The amyloid appeared as a weakly basophilic hyaline-like substance and stained with Congo red. Immunohistochemistry and liquid chromatography-tandem mass spectrometry revealed that the amyloid was composed of both N- and C-terminal EFEMP1 peptides. The amyloid fibrils were approximately 10 nm wide, unbranched, short and randomly arranged. The patient died from gastric bleeding caused by EFEMP1-derived amyloidosis. These findings suggest that EFEMP1-derived amyloidosis in Tsushima leopard cats has pathological features similar to those in affected humans, including amyloid deposition predominantly in the walls of veins and fatal gastrointestinal bleeding.</div></div>","PeriodicalId":15520,"journal":{"name":"Journal of Comparative Pathology","volume":"221 ","pages":"Pages 26-30"},"PeriodicalIF":0.9,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144721816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lingual liposarcoma transitioning from an infiltrative lipoma in a dog 犬舌脂肪肉瘤由浸润性脂肪瘤转变而来

IF 0.9 4区农林科学

Journal of Comparative Pathology Pub Date : 2025-07-29 DOI: 10.1016/j.jcpa.2025.07.008

Tae-Un Kim , Chan Huh , Jae-Hyuk Yim , Woo Jun Kim , Su-Min Baek , Jin-Kyu Park

{"title":"Lingual liposarcoma transitioning from an infiltrative lipoma in a dog","authors":"Tae-Un Kim , Chan Huh , Jae-Hyuk Yim , Woo Jun Kim , Su-Min Baek , Jin-Kyu Park","doi":"10.1016/j.jcpa.2025.07.008","DOIUrl":"10.1016/j.jcpa.2025.07.008","url":null,"abstract":"<div><div>Lingual neoplasms comprise approximately 2–4 % of canine oropharyngeal tumours, with liposarcomas being particularly rare and typically arising in the subcutis of the extremities and trunk. This report describes a 5-year-old spayed female Bedlington Terrier that presented with a ruptured lingual mass with muscular invasion, for which glossectomy was performed. Histopathological examination revealed a neoplastic proliferation of well-differentiated adipocytes that infiltrated the skeletal muscle layer. The deeper portion of the mass had dedifferentiation of adipocytes and malignant transformation into liposarcoma. The dedifferentiated neoplastic spindle cells contained cytoplasmic lipid vacuoles that stained positively with Oil Red O and had marked pleomorphism and elevated mitotic activity. Immunohistochemically, the neoplastic cells were positive for S100 and negative for CD34. While prior studies have suggested that liposarcomas do not originate from the malignant transformation of lipomas, the findings in this case support the possibility of infiltrative lipoma undergoing malignant transformation into a dedifferentiated and aggressive liposarcoma. This case underscores the potential for benign lipomatous lesions to evolve into their malignant counterparts under certain pathological conditions.</div></div>","PeriodicalId":15520,"journal":{"name":"Journal of Comparative Pathology","volume":"221 ","pages":"Pages 31-34"},"PeriodicalIF":0.9,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144721815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Premortem diagnosis of a pancreatic neuroendocrine tumour (glucagonoma) in a captive North American river otter (Lontra canadensis) 北美圈养水獭（Lontra canadensis）胰腺神经内分泌肿瘤（胰高血糖素瘤）的死前诊断

IF 0.8 4区农林科学

Journal of Comparative Pathology Pub Date : 2025-07-28 DOI: 10.1016/j.jcpa.2025.07.005

Kelsey M. Rayment , Michael M. Garner , Matti Kiupel , Ashley Magee , Carlos R. Sanchez

引用次数: 0