Journal of Clinical Monitoring and Computing最新文献_第5页

Clinical evaluation of a smart wristband for monitoring oxygen saturation, pulse rate, and respiratory rate. 对用于监测血氧饱和度、脉搏和呼吸频率的智能腕带进行临床评估。

IF 2 3区医学

Journal of Clinical Monitoring and Computing Pub Date : 2025-04-01 Epub Date: 2024-10-10 DOI: 10.1007/s10877-024-01229-z

Stefan H J Monnink, Mariska van Vliet, Mathijs J Kuiper, Jan C Constandse, Dieke Hoftijzer, Marjolein Muller, Eelko Ronner

{"title":"Clinical evaluation of a smart wristband for monitoring oxygen saturation, pulse rate, and respiratory rate.","authors":"Stefan H J Monnink, Mariska van Vliet, Mathijs J Kuiper, Jan C Constandse, Dieke Hoftijzer, Marjolein Muller, Eelko Ronner","doi":"10.1007/s10877-024-01229-z","DOIUrl":"10.1007/s10877-024-01229-z","url":null,"abstract":"Recently, photoplethysmography-based vital parameter measurements have increased in popularity. However, clinical evaluation of these measurements is lacking. The objective of this study was to rigorously evaluate the clinical accuracy and reliability of a novel photoplethysmography-based wristband for measuring key vital parameters-oxygen saturation (SpO2), respiratory rate (RR), and pulse rate (PR)-during heart catheterisations. Vital parameters obtained during heart catheterisations by means of a photoplethysmography-based wristband (CardioWatch 287-2, Corsano Health) were compared to reference measurements performed by a Nellcor fingerclip (SpO2, PR) as well as a 5-lead ECG (RR) (QMAPP Haemodynamic Monitoring module, Fysicon B.V.) by means of correlation coefficients and root means squared error (RMSE). Effects of skin colour and arm hair density were additionally evaluated. In total, 945 samples from a total of 100 patients were included in the analysis. The correlation coefficients and RSME obtained for the difference between reference and photoplethysmography-based wristband measurements were r = 0.815 and 1.6% for SpO2, r = 0.976 and 0.9 brpm for RR, and r = 0.995 and 1.3 bpm for PR. Similar results were obtained across all skin colour and arm hair density subcategories. This study shows that photoplethysmography-based SpO2, RR, and PR measurements can be accurate during heart catheterisations. Future investigations are required to evaluate the wristband's performance under dynamic circumstances as well as over an extended time period. Trial registration: www.clinicaltrials.gov, NCT05566886.","PeriodicalId":15513,"journal":{"name":"Journal of Clinical Monitoring and Computing","volume":" ","pages":"451-457"},"PeriodicalIF":2.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142400449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Characterization of the temporal profile of the antinociceptive effects of an intravenous bolus of ketamine using the analgesia nociception index in no-anesthetized adult patients. 在未麻醉的成年患者中使用镇痛痛觉指数分析静脉注射氯胺酮的抗痛觉作用的时间特征。

IF 2 3区医学

Journal of Clinical Monitoring and Computing Pub Date : 2025-04-01 Epub Date: 2024-11-15 DOI: 10.1007/s10877-024-01240-4

Víctor Navarrete, Mauricio Ibacache, Víctor Contreras, Ignacio Cortínez

{"title":"Characterization of the temporal profile of the antinociceptive effects of an intravenous bolus of ketamine using the analgesia nociception index in no-anesthetized adult patients.","authors":"Víctor Navarrete, Mauricio Ibacache, Víctor Contreras, Ignacio Cortínez","doi":"10.1007/s10877-024-01240-4","DOIUrl":"10.1007/s10877-024-01240-4","url":null,"abstract":"An effect-site target-controlled infusion (TCI) would allow a more precise titration of intravenous analgesics effect. The analgesia nociception index (ANI) continuously monitors the analgesia/nociception balance during general anesthesia. This study aims to derive a PKPD model of ketamine antinociceptive effect using the Domino PK parameter set and the ANI response data in awake patients without other drugs affecting the ANI response. Twenty awake adult patients were prospectively studied before general anesthesia. Patients received a single intravenous bolus of ketamine 0.1 mg·kg- 1, and the subsequent ANI values were recorded. An effect compartment model incorporating the Domino PK parameter set was used to characterize the time lag between ketamine plasma concentrations and the ANI response. The model was parameterized with a single parameter Ke0. An Emax pharmacodynamic model was used to fit the ANI response data. Model parameters were estimated with NONMEM® 7.5. The minimum objective function value guided the model construction. After the ketamine administration, basal ANI values increased from 38.5 ± 4.95 to a maximum of 53.5 ± 4.95 with an observed time-to-peak effect of 1.83 ± 0.74 min. Modeling analysis revealed hysteresis between predicted plasma concentrations from the Domino model and observed ANI data. Hysteresis was characterized, incorporating an estimated Keo of 0.238 (CI95% 0.20-0.28) min-1 to the described PK parameters set. The developed PKPD model, using Domino's PK parameters and the ANI response data, adequately characterized the temporal profile of ketamine's antinociceptive effect. The current estimated model parameters can be used to perform an effect-site TCI of ketamine for analgesic purposes.","PeriodicalId":15513,"journal":{"name":"Journal of Clinical Monitoring and Computing","volume":" ","pages":"349-354"},"PeriodicalIF":2.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142638984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Continuous monitoring after laparoscopic Roux-En-Y gastric bypass: a pathway to ambulatory care surgery - a pilot study. 腹腔镜 Roux-En-Y 胃旁路术后的持续监测：通往非住院护理手术的途径--一项试点研究。

IF 2 3区医学

Journal of Clinical Monitoring and Computing Pub Date : 2025-04-01 Epub Date: 2024-09-09 DOI: 10.1007/s10877-024-01216-4

Rui Ferreira-Santos, José Pedro Pinto, João Pedro Pinho, Ana Cristina Ribeiro, Maia da Costa, Vicente Vieira, Carmélia Ferreira, Fernando Manso, Joaquim Costa Pereira

{"title":"Continuous monitoring after laparoscopic Roux-En-Y gastric bypass: a pathway to ambulatory care surgery - a pilot study.","authors":"Rui Ferreira-Santos, José Pedro Pinto, João Pedro Pinho, Ana Cristina Ribeiro, Maia da Costa, Vicente Vieira, Carmélia Ferreira, Fernando Manso, Joaquim Costa Pereira","doi":"10.1007/s10877-024-01216-4","DOIUrl":"10.1007/s10877-024-01216-4","url":null,"abstract":"Same-day discharge (SDD) after Laparoscopic Roux-En-Y Gastric Bypass (LRYGB) faces resistance due to possible undetected postoperative complications. These present with changes in vital signs, which continuous remote monitoring devices can detect. This study compared continuous vital signs monitoring using the Isansys Patient Status Engine™ with standard nursing vital signs measurements to assess the device's reliability in postoperative surveillance of patients undergoing LRYGB. We conducted a pilot study including patients who underwent LRYGB. During their hospital stay, patients were continuously monitored using the Isansys Patient Status Engine™ with Lifetouch™, Lifetemp™, and Nonin Pulse Oximeter™ sensors. The heart rate (HR), body temperature, and oxygen saturation (SpO2) collected by the device were compared with standard nursing assessments. Thirteen patients with a mean body mass index of 41.5 ± 4.4 kg/m2 were included. No major complications occurred. The median HR assessed by standard and continuous monitoring did not significantly differ (75.5 [69-88] vs. 77 [66-91] bpm, p = 0.995), nor did the mean values of SpO2 (94.7 ± 2.0 vs. 93.7 ± 1.8%, p = 0,057). A significant difference was observed in median body temperature between the nursing staff and the monitoring device (36.3 [36.1-36.7] vs. 36.1 [34.5-36.6] degrees Celsius, p = 0.012), with a tendency for lower temperature measurements by the device. In conclusion, this is the first study on continuous postoperative surveillance using the Isansys Patient Status Engine™ monitoring device for LRYGB patients. Our results introduce a novel tool for more efficient surgery. Prospective randomized experimental studies are warranted to evaluate this method's efficacy and safety.","PeriodicalId":15513,"journal":{"name":"Journal of Clinical Monitoring and Computing","volume":" ","pages":"443-449"},"PeriodicalIF":2.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142154266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Susceptibility of two different PCA pumps to inaccurate delivery associated with pole position at low flow-rates in a pediatric setting - an experimental study. 在儿科环境中，两种不同的 PCA 泵在低流速时因极点位置而导致输液不准确的可能性--一项实验研究。

IF 2 3区医学

Journal of Clinical Monitoring and Computing Pub Date : 2025-04-01 Epub Date: 2024-10-12 DOI: 10.1007/s10877-024-01233-3

Judith E Riemer, Nathalie C Greber, Melanie Frühauf, Markus Weiss, Tobias Piegeler

{"title":"Susceptibility of two different PCA pumps to inaccurate delivery associated with pole position at low flow-rates in a pediatric setting - an experimental study.","authors":"Judith E Riemer, Nathalie C Greber, Melanie Frühauf, Markus Weiss, Tobias Piegeler","doi":"10.1007/s10877-024-01233-3","DOIUrl":"10.1007/s10877-024-01233-3","url":null,"abstract":"Purpose: Vertical displacement of infusion pumps used in patient-controlled analgesia can cause irregularities in drug delivery and is especially crucial at low flow rates, which are commonly used in pediatrics. There is only scarce data available regarding the extent of these inaccuracies. The current in vitro study therefore aimed at a comparison of the performance of two commonly used PCA pumps at different pole positions due to vertical displacement.Methods: The Syramed® µSP6000 Chroma syringe infusion pump featuring a stepper motor drive was compared to the CADD®-Solis pump utilizing a linear peristaltic pump system at two different flow rates (0.3 ml/h and 1 ml/h) and three different levels of height (0, + 50 and - 50 cm). Flow patterns and delivered volumes were measured after every change in position and infusion boluses, retrograde aspiration volumes and zero-drug delivery time were calculated.Results: The Syramed® pump was more susceptible to vertical displacement than the CADD®-Solis pump and showed overall greater inaccuracies in the delivered volumes as well as higher infusion boluses, retrograde aspiration volumes and zero-drug delivery time at both flow rates.Conclusion: The observed differences between the pumps might be explained by the higher compliance of this syringe pump and the diverse working mechanisms. Overall, the CADD®-Solis pump might be considered a preferable option for patient-controlled analgesia in children. It is nonetheless essential for medical staff to be aware of the effects of vertical displacement of PCA pumps and to minimize these displacements as much as possible.","PeriodicalId":15513,"journal":{"name":"Journal of Clinical Monitoring and Computing","volume":" ","pages":"469-479"},"PeriodicalIF":2.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142406455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An open source autoregulation-based neuromonitoring algorithm shows PRx and optimal CPP association with pediatric traumatic brain injury. 一种开源的基于自调节的神经监测算法显示，PRx和最佳CPP与儿童创伤性脑损伤有关。

IF 2 3区医学

Journal of Clinical Monitoring and Computing Pub Date : 2025-04-01 Epub Date: 2024-12-19 DOI: 10.1007/s10877-024-01248-w

Eris van Twist, Tahisa B Robles, Bart Formsma, Naomi Ketharanathan, Maayke Hunfeld, C M Buysse, Matthijs de Hoog, Alfred C Schouten, Rogier C J de Jonge, Jan W Kuiper

{"title":"An open source autoregulation-based neuromonitoring algorithm shows PRx and optimal CPP association with pediatric traumatic brain injury.","authors":"Eris van Twist, Tahisa B Robles, Bart Formsma, Naomi Ketharanathan, Maayke Hunfeld, C M Buysse, Matthijs de Hoog, Alfred C Schouten, Rogier C J de Jonge, Jan W Kuiper","doi":"10.1007/s10877-024-01248-w","DOIUrl":"10.1007/s10877-024-01248-w","url":null,"abstract":"This study aimed to develop an open-source algorithm for the pressure-reactivity index (PRx) to monitor cerebral autoregulation (CA) in pediatric severe traumatic brain injury (sTBI) and compared derived optimal cerebral perfusion pressure (CPPopt) with real-time CPP in relation to long-term outcome. Retrospective study in children (< 18 years) with sTBI admitted to the pediatric intensive care unit (PICU) for intracranial pressure (ICP) monitoring between 2016 and 2023. ICP was analyzed on an insult basis and correlated with outcome. PRx was calculated as Pearson correlation coefficient between ICP and mean arterial pressure. CPPopt was derived as weighted average of CPP-PRx over time. Outcome was determined via Pediatric Cerebral Performance Category (PCPC) scale at one year post-injury. Logistic regression and mixed effect models were developed to associate PRx and CPPopt with outcome. In total 50 children were included, 35 with favorable (PCPC 1-3) and 15 with unfavorable outcome (PCPC 4-6). ICP insults correlated with unfavorable outcome at 20 mmHg for 7 min duration. Mean CPPopt yield was 75.4% of monitoring time. Mean and median PRx and CPPopt yield associated with unfavorable outcome, with odds ratio (OR) 2.49 (1.38-4.50), 1.38 (1.08-1.76) and 0.95 (0.92-0.97) (p < 0.001). PRx thresholds 0.0, 0.20, 0.25 and 0.30 resulted in OR 1.01 (1.00-1.02) (p < 0.006). CPP in optimal range associated with unfavorable outcome on day one (0.018, p = 0.029) and four (-0.026, p = 0.025). Our algorithm can obtain optimal targets for pediatric neuromonitoring that showed association with long-term outcome, and is now available open source.","PeriodicalId":15513,"journal":{"name":"Journal of Clinical Monitoring and Computing","volume":" ","pages":"291-299"},"PeriodicalIF":2.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12049323/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142864505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

New sensors for the early detection of clinical deterioration on general wards and beyond - a clinician's perspective. 用于早期检测普通病房临床病情恶化的新型传感器--临床医生的视角。

IF 2 3区医学

Journal of Clinical Monitoring and Computing Pub Date : 2025-04-01 Epub Date: 2024-11-15 DOI: 10.1007/s10877-024-01235-1

Frederic Michard, Bernd Saugel

{"title":"New sensors for the early detection of clinical deterioration on general wards and beyond - a clinician's perspective.","authors":"Frederic Michard, Bernd Saugel","doi":"10.1007/s10877-024-01235-1","DOIUrl":"10.1007/s10877-024-01235-1","url":null,"abstract":"The early detection of clinical deterioration could be the next significant step in enhancing patient safety in general hospital wards. Most patients do not deteriorate suddenly; instead, their vital signs are often abnormal or trending towards an abnormal range hours before severe adverse events requiring rescue intervention and/or ICU transfer. To date, at least 10 large clinical studies have demonstrated a significant reduction in severe adverse events when heart rate, blood pressure, oxygen saturation and/or respiratory rate are continuously monitored on medical and surgical wards. Continuous, silent, and automatic monitoring of vital signs also presents the opportunity to eliminate unnecessary spot-checks for stable patients. This could lead to a reduction in nurse workload, while significantly improving patient comfort, sleep quality, and overall satisfaction. Wireless and wearable sensors are particularly valuable, as they make continuous monitoring feasible even for ambulatory patients, raising questions about the future relevance of \"stay-in-bed\" solutions like capnography, bed sensors, and video-monitoring systems. While the number of wearable sensors and mobile monitoring solutions is rapidly growing, independent validation studies on their sensitivity and specificity in detecting abnormal vital signs in actual patients, rather than healthy volunteers, remain limited. Additionally, further research is needed to evaluate the cost-effectiveness of using wireless wearables for vital sign monitoring both within hospital wards and at home.","PeriodicalId":15513,"journal":{"name":"Journal of Clinical Monitoring and Computing","volume":" ","pages":"435-442"},"PeriodicalIF":2.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142638987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relationship between the amplitudes of cerebral blood flow velocity and intracranial pressure using linear and non-linear approach. 用线性和非线性方法研究脑血流速度与颅内压的关系。

IF 2 3区医学

Journal of Clinical Monitoring and Computing Pub Date : 2025-04-01 Epub Date: 2024-12-10 DOI: 10.1007/s10877-024-01243-1

Adam I Pelah, Monika Najdek, Marek Czosnyka, Agnieszka Uryga

{"title":"Relationship between the amplitudes of cerebral blood flow velocity and intracranial pressure using linear and non-linear approach.","authors":"Adam I Pelah, Monika Najdek, Marek Czosnyka, Agnieszka Uryga","doi":"10.1007/s10877-024-01243-1","DOIUrl":"10.1007/s10877-024-01243-1","url":null,"abstract":"Intracranial pressure (ICP), cerebral blood flow and volume are affected by craniospinal elasticity and cerebrospinal fluid dynamics, interacting in complex, nonlinear ways. Traumatic brain injury (TBI) may significantly alter this relationship. This retrospective study investigated the relationship between the vascular and parenchymal intracranial compartments by analysing two amplitudes: cerebral blood flow velocity (AmpCBFV) and ICP (AMP) during hypocapnia manoeuvre in TBI patients. Twenty-nine TBI patients hospitalised at Addenbrooke's Hospital, whose ICP and CBFV were monitored during mild hypocapnia, were included. A linear metric of the relationship was defined as a moving-window correlation (R) between AmpCBFV and AMP, named RAMP. Nonlinear metrics were based on the Joint Symbolical Analysis (JSA) algorithm, which transforms AmpCBFV and AMP into sequences of symbols ('words') using a binary scheme with word lengths of three. The mean AmpCBFV and AMP were not significantly correlated at baseline (r = - 0.10) or during hypocapnia (r = - 0.19). However, the RAMP index was significantly higher at baseline (0.64 ± 0.04) compared to hypocapnia (0.57 ± 0.04, p = 0.035). The relative frequency of symmetrical word types (JSAsym) describing the AmpCBFV-AMP interaction decreased during hypocapnia (0.35 ± 0.30) compared to baseline (0.44 ± 0.030; p = 0.004). Our results indicate that while the grouped-averaged AmpCBFV and AMP were not significantly correlated, either at baseline or during hypocapnia, significant changes were observed when using RAMP and JSA indices. Further validation of these new parameters, which reflect the association between the vascular and parenchymal intracranial compartments, is needed in a larger cohort.","PeriodicalId":15513,"journal":{"name":"Journal of Clinical Monitoring and Computing","volume":" ","pages":"301-313"},"PeriodicalIF":2.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12049393/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142800162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Regional cerebral oxygen saturation in the healthy population of western Sichuan: a multicenter cross-sectional study. 四川西部健康人群的区域脑氧饱和度：一项多中心横断面研究。

IF 2 3区医学

Journal of Clinical Monitoring and Computing Pub Date : 2025-04-01 Epub Date: 2024-11-25 DOI: 10.1007/s10877-024-01244-0

Gangfeng Gu, Junyao Jiang, Bo Zheng, Yan Li, Yuding Luo, Yunhai Pu, Jian Wang

{"title":"Regional cerebral oxygen saturation in the healthy population of western Sichuan: a multicenter cross-sectional study.","authors":"Gangfeng Gu, Junyao Jiang, Bo Zheng, Yan Li, Yuding Luo, Yunhai Pu, Jian Wang","doi":"10.1007/s10877-024-01244-0","DOIUrl":"10.1007/s10877-024-01244-0","url":null,"abstract":"Regional cerebral oxygen saturation (rSO2) may vary in healthy individuals with different characteristics. Therefore, this study aimed to explore rSO2 in a healthy population of western Sichuan. This cross-sectional study enrolled healthy volunteers from the Health Management Center and Inpatient Department of Ya'an People's Hospital, Ya'an Vocational and Technical College, Ya'an Geriatric University, and Liziping Yi Township in Shimian County, Ya'an City, Sichuan Province. Brain rSO2 was measured by near-infrared spectroscopy (NIRS) between January 2020 and December 2022. A total of 661 volunteers were enrolled, with a mean age of 28.3 ± 23.1 years old and 276 males. There was significantly higher rSO2 of the left brain in females (63.46 ± 3.01 vs. 63.17 ± 2.90, P = 0.015), males (63.91 ± 3.54 vs. 63.42 ± 3.32, P = 0.002), Han (65.10 ± 3.67 vs. 64.38 ± 3.43, P < 0.001), and volunteers aged 14-59 years (P < 0.05) compared with the right brain. Volunteers with Han ethnicity had significantly higher rSO2 than those with Yi ethnicity (64.65 ± 3.29 vs. 62.68 ± 3.66, P < 0.001). Volunteers with past illness had significantly lower rSO2 than those without past illness (62.41 ± 3.06 vs. 62.68 ± 3.66, P = 0.021). Pearson correlation analysis showed a significantly negative correlation of rSO2 with age, ethics, past illness, and body mass index (BMI) but a significantly positive correlation with head circumference and height (all P < 0.05). The rSO2 values in the left brain are significantly higher than in the right brain. Sex, ethnicity, age, BMI, and past illness are closely related to rSO2 values in the healthy population.","PeriodicalId":15513,"journal":{"name":"Journal of Clinical Monitoring and Computing","volume":" ","pages":"283-289"},"PeriodicalIF":2.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12049316/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142710186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of a low-cost portable NIRS device for monitoring muscle ischemia. 评估用于监测肌肉缺血的低成本便携式近红外设备。

IF 2 3区医学

Journal of Clinical Monitoring and Computing Pub Date : 2025-04-01 Epub Date: 2024-10-02 DOI: 10.1007/s10877-024-01226-2

Ramsés Marrero-García, Yaiza Cruz-Tabares, Jose M Gonzalez-Cava, Juan Albino Méndez-Pérez, José Antonio Reboso-Morales

{"title":"Evaluation of a low-cost portable NIRS device for monitoring muscle ischemia.","authors":"Ramsés Marrero-García, Yaiza Cruz-Tabares, Jose M Gonzalez-Cava, Juan Albino Méndez-Pérez, José Antonio Reboso-Morales","doi":"10.1007/s10877-024-01226-2","DOIUrl":"10.1007/s10877-024-01226-2","url":null,"abstract":"The main objective of this study is to evaluate the low-cost, open-source HEGduino device as a tissue oximetry monitor to advance the research of somatic NIRS monitoring. Specifically, this study analyzes the use of this portable functional NIRS system for detecting the cessation of blood flow due to vascular occlusion in an upper limb. 19 healthy patients aged between 25 and 50 were recruited and monitored using HEGduino device. Participants underwent a vascular occlusion test on one forearm. Raw values collected by HEGduino as well as the processed variables derived from the measurements were registered. Additional variables to characterize the signal noise during the tests were also recorded. The results of the data distribution curves for all the subjects in the study accurately detected the physiological events associated with transient tissue ischemia. The statistical analysis of the recorded data showed that the difference between the baseline values recorded by the red led (RED) and its normalized minimum variable was always different from zero (p < 0.014). Furthermore, the difference between the normalized baseline values recorded by the infrared led (IR) and the corresponding normalized minimum value was also different from zero (p < 0.001). The R-squared coefficient of determination for the noise variables considered in this study on the normalized RED and IR values was 0.08 and 0.105, respectively. The study confirms the potential of HEGduino system to detect an interruption of the blood flow by means of variations in regional tissue oxygen saturation. This study demonstrates the potential of the HEGduino device as a monitoring alternative to advance the study of the applicability of NIRS in muscle tissue oximetry.","PeriodicalId":15513,"journal":{"name":"Journal of Clinical Monitoring and Computing","volume":" ","pages":"459-468"},"PeriodicalIF":2.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142361631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Capnodynamic determination of end-expiratory lung volume in a porcine model of hypoxic pulmonary vasoconstriction. 猪缺氧肺血管收缩模型呼气末肺容量的二氧化碳动力学测定。

IF 2 3区医学

Journal of Clinical Monitoring and Computing Pub Date : 2025-04-01 Epub Date: 2024-12-12 DOI: 10.1007/s10877-024-01251-1

Aron Törnwall, Mats Wallin, Magnus Hallbäck, Per-Arne Lönnqvist, Jacob Karlsson

{"title":"Capnodynamic determination of end-expiratory lung volume in a porcine model of hypoxic pulmonary vasoconstriction.","authors":"Aron Törnwall, Mats Wallin, Magnus Hallbäck, Per-Arne Lönnqvist, Jacob Karlsson","doi":"10.1007/s10877-024-01251-1","DOIUrl":"10.1007/s10877-024-01251-1","url":null,"abstract":"Purpose: The capnodynamic method, End Expiratory Lung Volume CO2 (EELV-CO2), utilizes exhaled carbon dioxide analysis to estimate End-Expiratory Lung Volume (EELV) and has been validated in both normal lungs and lung injury models. Its performance under systemic hypoxia and variations in CO2 elimination is not examined. This study aims to validate EELV-CO2 against inert gas wash in/wash out (EELV- SF6, sulfur hexafluoride) in a porcine model of stable hemodynamic conditions followed by hypoxic pulmonary vasoconstriction and inhaled nitric oxide (iNO).Methods: Ten mechanically ventilated piglets were exposed to a hypoxic gas mixture and selective pulmonary vasoconstriction. Inhalation of nitric oxide was used to reverse the pulmonary vasoconstriction. Paired recordings of EELV-CO2 and EELV-SF6, were conducted to assess their agreement of absolute values.Results: EELV-CO2 showed a bias of + 5 ml kg- 1 compared to EELV-SF6, upper limit of agreement of 11 ml kg- 1 (95%CI: 9-13 ml kg- 1), lower limit of agreement - 1 ml kg- 1 (95%CI: -3- 0 ml kg- 1), mean percentage error 34%. Agreement between EELV-CO2 and EELV-SF6 was largely constant but was affected by progressing hypoxia and reached maximum limit of agreement after iNO exposure. Re-introduction of normoxemia then stabilized bias and limits of agreement to baseline levels.Conclusion: EELV-CO2 generates absolute values in parallel with EELV -SF6. Stressing EELV-CO2 with hypoxic pulmonary vasoconstriction and iNO, transiently impairs the agreement which stabilizes once normoxemia is reestablished.","PeriodicalId":15513,"journal":{"name":"Journal of Clinical Monitoring and Computing","volume":" ","pages":"405-413"},"PeriodicalIF":2.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12049395/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142813143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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