Journal of Clinical Monitoring and Computing最新文献

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Haemodynamic monitoring and management during non-cardiac surgery: a survey among German anaesthesiologists. 非心脏手术期间的血流动力学监测和管理:德国麻醉师的调查。
IF 2 3区 医学
Journal of Clinical Monitoring and Computing Pub Date : 2025-03-22 DOI: 10.1007/s10877-025-01284-0
Benjamin Vojnar, Patrick Achenbach, Moritz Flick, Daniel Reuter, Michael Sander, Bernd Saugel, Ann-Kristin Schubert, Christine Gaik
{"title":"Haemodynamic monitoring and management during non-cardiac surgery: a survey among German anaesthesiologists.","authors":"Benjamin Vojnar, Patrick Achenbach, Moritz Flick, Daniel Reuter, Michael Sander, Bernd Saugel, Ann-Kristin Schubert, Christine Gaik","doi":"10.1007/s10877-025-01284-0","DOIUrl":"https://doi.org/10.1007/s10877-025-01284-0","url":null,"abstract":"<p><p>In 2023, the first German guideline on intraoperative haemodynamic monitoring and management for adults having non-cardiac surgery was published. The aim of this survey was to identify how anaesthetists in Germany managed intraoperative haemodynamics and blood pressure before its publication. In September to October 2023, members of the German Society of Anaesthesiology and Intensive Care Medicine (DGAI) were invited via email to participate in this anonymous online survey. Thirty-one questions covered demographics, clinical experience, approaches to perioperative blood pressure measurement and common thresholds, as well as the use of advanced haemodynamic monitoring and its potential therapeutic implications. 1,079 fully completed questionnaires were included in the analysis. When intermittent oscillometry was used to measure blood pressure, a 3-minute interval was usually applied during induction of anaesthesia (42%; 451/1,079). For invasive blood pressure monitoring, more than half (53%; 574/1,079) inserted an arterial line after induction of anaesthesia. Nearly all (94%; 1,012/1,079) focused on the mean arterial pressure for blood pressure monitoring, with a large majority (77%; 779/1012) considering values below 60-65 mmHg to be critically low. Intraoperative hypotension was managed based on an internal protocol by only 21% (223/1,079). Regarding advanced haemodynamic monitoring, 43% (459/1,079) frequently used pulse contour analysis, while 67% (721/1,079) reported that monitors with finger-cuff technology were not available in their department. 47% (504/1,079) cited a lack of experience as one of the main reasons for the infrequent use of cardiac output monitoring. This survey among DGAI members provides important insights into current practices of haemodynamic monitoring and management prior to the publication of the recent German guideline on 'Intraoperative haemodynamic monitoring and management of adults having non-cardiac surgery'.</p>","PeriodicalId":15513,"journal":{"name":"Journal of Clinical Monitoring and Computing","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143692349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reliability of an all-in-one wearable sensor for continuous vital signs monitoring in high-risk patients: the NIGHTINGALE clinical validation study. 用于高危患者连续生命体征监测的一体化可穿戴传感器的可靠性:NIGHTINGALE临床验证研究
IF 2 3区 医学
Journal of Clinical Monitoring and Computing Pub Date : 2025-03-18 DOI: 10.1007/s10877-025-01279-x
Martine J M Breteler, Ellen Leigard, Lisa C Hartung, John R Welch, David A Brealey, Sebastian J Fritsch, David Konrad, Daniel Hertzberg, Max Bell, Heleen Rienstra, Frank E Rademakers, Cor J Kalkman
{"title":"Reliability of an all-in-one wearable sensor for continuous vital signs monitoring in high-risk patients: the NIGHTINGALE clinical validation study.","authors":"Martine J M Breteler, Ellen Leigard, Lisa C Hartung, John R Welch, David A Brealey, Sebastian J Fritsch, David Konrad, Daniel Hertzberg, Max Bell, Heleen Rienstra, Frank E Rademakers, Cor J Kalkman","doi":"10.1007/s10877-025-01279-x","DOIUrl":"https://doi.org/10.1007/s10877-025-01279-x","url":null,"abstract":"<p><p>Continuous vital signs monitoring with wearable systems may improve early recognition of patient deterioration on hospital wards. The objective of this study was to determine whether the wearable Checkpoint Cardio's CPC12S, can accurately measure heart rate (HR), respiratory rate (RR), oxygen saturation (SpO2), blood pressure (BP) and temperature continuously. In an observational multicenter method comparison study of 70 high-risk surgical patients admitted to high-dependency wards; HR, RR, SpO2, BP and temperature were simultaneously measured with the CPC12S system and with ICU-grade monitoring systems in four European hospitals. Outcome measures were bias and 95% limits of agreement (LoA). Clinical accuracy was assessed with Clarke Error Grid analyses for HR and RR. A total of 3,212 h of vital signs data (on average 26 h per patient) were analyzed. For HR, bias (95% LoA) of the pooled analysis was 0.0 (-3.5 to 3.4), for RR 1.5 (-3.7 to 7.5) and for SpO2 0.4 (-3.1 to 4.0). The CPC12S system overestimated BP, with a bias of 8.9 and wide LoA (-23.3 to 41.2). Temperature was underestimated with a bias of -0.6 and LoA of -1.7 to 0.6. Clarke Error Grid analyses showed that adequate treatment decisions regarding changes in HR and RR would have been made in 99.2% and 92.0% of cases respectively. The CPC12S system showed high accuracy for measurements of HR. The accuracy of RR, SpO2 were slightly overestimated and core temperature underestimated, with LoA outside the predefined clinical acceptable range. The accuracy of BP was unacceptably low.</p>","PeriodicalId":15513,"journal":{"name":"Journal of Clinical Monitoring and Computing","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143657341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Postoperative use of fitness trackers for continuous monitoring of vital signs: a survey of hospitalized patients. 术后使用健身追踪器持续监测生命体征:一项住院患者调查。
IF 2 3区 医学
Journal of Clinical Monitoring and Computing Pub Date : 2025-03-06 DOI: 10.1007/s10877-025-01273-3
Philipp Helmer, Sebastian Hottenrott, Kathrin Wienböker, Jürgen Brugger, Christian Stoppe, Benedikt Schmid, Peter Kranke, Patrick Meybohm, Michael Sammeth
{"title":"Postoperative use of fitness trackers for continuous monitoring of vital signs: a survey of hospitalized patients.","authors":"Philipp Helmer, Sebastian Hottenrott, Kathrin Wienböker, Jürgen Brugger, Christian Stoppe, Benedikt Schmid, Peter Kranke, Patrick Meybohm, Michael Sammeth","doi":"10.1007/s10877-025-01273-3","DOIUrl":"https://doi.org/10.1007/s10877-025-01273-3","url":null,"abstract":"<p><p>Wearables and Internet of Things (IoT) technologies are increasingly incorporated into healthcare, including perioperative settings. These devices offer continuous non-invasive monitoring of vital signs, patient position, and mobilization. Nonetheless, there is currently little information about tolerance and acceptance of wearables in postoperative patients. We therefore assessed opinions and user experience in postoperative patients who used three popular fitness trackers during their entire hospital stay. Specifically, we evaluate the Apple Watch 7, Garmin Fenix 6 Pro, and Withings ScanWatch. We used an investigator-designed patient questionnaire with 11 questions to quantify patient experience and opinions regarding inpatient and home monitoring. Secondarily, we evaluated compliance and the incidence of associated adverse events during daily patient visits. Data were analyzed using descriptive statistics and non-parametric tests. The majority of the answers to the questions (82.1%) were rated positively defined as Likert-Scale Scores 4 or 5 by the 33 analyzed patients, ranging between 72.7 and 97.0% agreement rate. Specific questions related to data sharing for research and overall user experience received high agreement rates (97.0 and 84.8%, respectively). Women reported slightly higher satisfaction with device comfort, as compared to men (LS-Score 4.8 vs. 4.0). No significant differences were found based on the device model or length of hospitalization. The use of wearable devices in healthcare is rated positively by postoperative inpatients, paving the way for future implementation of these devices in healthcare. However, besides validating the measurement accuracy and demonstrating clinical benefits, several regulatory hurdles must be overcome before implementing wearables in routine clinical care.</p>","PeriodicalId":15513,"journal":{"name":"Journal of Clinical Monitoring and Computing","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143572915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Electrical impedance tomography for PEEP titration in ARDS patients: a systematic review and meta-analysis. 电阻抗断层扫描用于ARDS患者PEEP滴定:系统回顾和荟萃分析。
IF 2 3区 医学
Journal of Clinical Monitoring and Computing Pub Date : 2025-02-26 DOI: 10.1007/s10877-025-01266-2
Carlos Sanchez-Piedra, Begoña Rodríguez-Ortiz-de-Salazar, Oriol Roca, Francisco-Javier Prado-Galbarro, Lilisbeth Perestelo-Perez, Luis-Maria Sanchez-Gomez
{"title":"Electrical impedance tomography for PEEP titration in ARDS patients: a systematic review and meta-analysis.","authors":"Carlos Sanchez-Piedra, Begoña Rodríguez-Ortiz-de-Salazar, Oriol Roca, Francisco-Javier Prado-Galbarro, Lilisbeth Perestelo-Perez, Luis-Maria Sanchez-Gomez","doi":"10.1007/s10877-025-01266-2","DOIUrl":"10.1007/s10877-025-01266-2","url":null,"abstract":"<p><p>To assess the efficacy of electrical impedance tomography (EIT)-guided positive end-expiratory pressure (PEEP) titration in improving outcomes for patients with acute respiratory distress syndrome (ARDS). A systematic review and meta-analysis was conducted following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Randomized controlled trials and observational studies with a control group comparing EIT-guided PEEP titration to other strategies were included. Endpoints analysed included mortality, days of mechanical ventilation (MV), intensive care unit (ICU) length of stay (LOS), weaning success rate, barotrauma, driving pressure (∆P), mechanical power (MP), Sequential Organ Failure Assessment (SOFA) score and adverse events. Pooled results were presented as Risk Ratio (RR) for dichotomous outcomes and standardized difference in means (SMD) for continuous outcomes. A total of 4 studies were identified (3 randomized controlled trials and one observational study). All studies were single-center studies (N total = 271 patients). The main limitations were related to potential bias in selecting reported outcomes. EIT-guided PEEP titration was associated with a significant reduction in mortality among critically ill patients with ARDS (RR = 0.64, 95% CI: 0.45-0.91). No significant differences were found in other outcomes. Our findings suggest that EIT may be a valuable tool for PEEP titration in critically ill patients with ARDS. By optimizing lung mechanics, EIT-guided PEEP titration may potentially reduce mortality rates. While larger, multicenter studies are needed to definitively establish the clinical role of EIT in ARDS management, our results provide promising evidence for its potential clinical impact.</p>","PeriodicalId":15513,"journal":{"name":"Journal of Clinical Monitoring and Computing","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143515831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
DiCARTTM device to measure capillary refill time: a validation study in patients with acute circulatory failure. DiCARTTM装置测量毛细血管再充血时间:急性循环衰竭患者的验证研究。
IF 2 3区 医学
Journal of Clinical Monitoring and Computing Pub Date : 2025-02-26 DOI: 10.1007/s10877-025-01271-5
Alexandre Descamps, Matthias Jacquet-Lagrèze, Thomas Aussal, Jean-Luc Fellahi, Martin Ruste
{"title":"DiCART<sup>TM</sup> device to measure capillary refill time: a validation study in patients with acute circulatory failure.","authors":"Alexandre Descamps, Matthias Jacquet-Lagrèze, Thomas Aussal, Jean-Luc Fellahi, Martin Ruste","doi":"10.1007/s10877-025-01271-5","DOIUrl":"https://doi.org/10.1007/s10877-025-01271-5","url":null,"abstract":"<p><p>Capillary Refill Time (CRT) is a valuable metric to assess cutaneous perfusion. Its prognostic value in patients with acute circulatory failure has been reported as improved when the measurement is standardized. The DiCART™ device is a fully automated CRT measurement tool requiring validation. We conducted a comparative interventional single-center study including 25 patients with acute circulatory failure, to evaluate the agreement between CRT measured by an automated measurement device (CRT<sub>DiCART</sub>) and CRT measured clinically (CRT<sub>CLIN</sub>). CRT was measured on the fingertip, chest, and knee. Three measurements were performed at each location to obtain an average for each site. The measurements were conducted both clinically and using the DiCART™ device by two different operators, each blinded to the results. Agreement was determined using intraclass correlation coefficient (ICC) and Bland and Altman analysis. The ICC between CRT<sub>CLIN</sub> and CRT<sub>DiCART</sub> was 0.46 (95% Confidence Interval (CI) 0.32, 0.59) across all measurement sites; the mean bias was 0.23s (95% CI -0.17, 0.64), with upper Limit of Agreement (LoA) 2.77s (95% CI 2.44, 3.20) and lower LoA - 2.30s (-2.73, -1.97). Intra observer ICC was 0.85 (95% CI 0.74, 0.91) for CRT<sub>CLIN</sub> and 0.43 (95% CI 0.15, 0.64) for CRT<sub>DICART</sub>. Inter observer ICC was 0.86 (95% CI 0.76, 0.92) for CRT<sub>CLIN</sub> and was 0.41 (95% CI 0.14, 0,63) for CRT<sub>DICART</sub>. The DiCART™ device showed poor agreement with clinical CRT in patients with acute circulatory failure, which does not support its use in routine practice.</p>","PeriodicalId":15513,"journal":{"name":"Journal of Clinical Monitoring and Computing","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143515824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Personalized intraoperative arterial pressure management and mitochondrial oxygen tension in patients having major non-cardiac surgery: a pilot substudy of the IMPROVE trial. 重大非心脏手术患者的个体化术中动脉压管理和线粒体氧张力:改进试验的试点亚研究
IF 2 3区 医学
Journal of Clinical Monitoring and Computing Pub Date : 2025-02-07 DOI: 10.1007/s10877-024-01260-0
Moritz Flick, Christina Vokuhl, Alina Bergholz, Kristina Boutchkova, Julia Y Nicklas, Bernd Saugel
{"title":"Personalized intraoperative arterial pressure management and mitochondrial oxygen tension in patients having major non-cardiac surgery: a pilot substudy of the IMPROVE trial.","authors":"Moritz Flick, Christina Vokuhl, Alina Bergholz, Kristina Boutchkova, Julia Y Nicklas, Bernd Saugel","doi":"10.1007/s10877-024-01260-0","DOIUrl":"https://doi.org/10.1007/s10877-024-01260-0","url":null,"abstract":"<p><p>The \"Cellular Oxygen METabolism\" (COMET) system (Photonics Healthcare, Utrecht, The Netherlands) non-invasively measures mitochondrial oxygen tension (mitoPO<sub>2</sub>) in the skin. The effects of general anesthesia and major non-cardiac surgery on mitoPO<sub>2</sub> remain unknown. In this pre-planned pilot substudy of the \"Intraoperative blood pressure Management based on the individual blood PRessure profile: impact on postOperatiVE organ function\" (IMPROVE) trial, we measured mitoPO<sub>2</sub> from induction of general anesthesia until the end of surgery in 19 major non-cardiac surgery patients (10 assigned to personalized and 9 to routine intraoperative arterial pressure management). In the overall cohort, the median (25th to 75th percentile) preoperative awake mitoPO<sub>2</sub> was 63 (53 to 82) mmHg and mitoPO<sub>2</sub> after induction of general anesthesia was 42 (35 to 59) mmHg. The intraoperative average mitoPO<sub>2</sub> was 39 (30 to 50) mmHg. Thirteen patients (68%) had intraoperative mitoPO<sub>2</sub> values below 20 mmHg and the median percentage of surgical time with mitoPO<sub>2</sub> < 20 mmHg was 17 (0 to 31)%. MitoPO<sub>2</sub> was weakly correlated with mean arterial pressure (repeated measures correlation (r<sub>rm</sub>(n); r<sub>rm</sub>(984) = 0.26, 95% confidence interval 0.20 to 0.32; P < 0.001), but not meaningfully with heart rate (r<sub>rm</sub>(984) = -0.05, 95% confidence interval -0.11 to 0.01; P = 0.117). There was no important difference in intraoperative average mitoPO<sub>2</sub> between patients assigned to personalized or to routine intraoperative arterial pressure management (P = 0.653). MitoPO<sub>2</sub> under general anesthesia was about a quarter lower than preoperative awake mitoPO<sub>2</sub>, substantially fluctuated during major non-cardiac surgery, and transiently decreased below 20 mmHg in about two-thirds of the patients. Personalized - compared to routine - intraoperative arterial pressure management did not increase intraoperative mitoPO<sub>2</sub>. Whether intraoperative decreases in mitoPO<sub>2</sub> are clinically meaningful warrants further investigation.</p>","PeriodicalId":15513,"journal":{"name":"Journal of Clinical Monitoring and Computing","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143370833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reversal of neuromuscular block with neostigmine and sugammadex: a retrospective cohort study in two centers using different types of neuromuscular monitoring. 使用新斯的明和苏加麦克斯逆转神经肌肉阻滞:在两个使用不同类型神经肌肉监测的中心进行的回顾性队列研究。
IF 2 3区 医学
Journal of Clinical Monitoring and Computing Pub Date : 2025-02-01 Epub Date: 2024-07-20 DOI: 10.1007/s10877-024-01192-9
Cyrus Motamed, Bernard Trillat, Marc Fischler, Morgan le Guen, Jean Louis Bourgain
{"title":"Reversal of neuromuscular block with neostigmine and sugammadex: a retrospective cohort study in two centers using different types of neuromuscular monitoring.","authors":"Cyrus Motamed, Bernard Trillat, Marc Fischler, Morgan le Guen, Jean Louis Bourgain","doi":"10.1007/s10877-024-01192-9","DOIUrl":"10.1007/s10877-024-01192-9","url":null,"abstract":"<p><p>This bicentric retrospective cohort study evaluates reversal of muscle relaxation in real life achieved either by neostigmine or sugammadex in two hospitals using different types of neuromuscular monitoring (acceleromyography and kinemyography). The research question concerns compliance with recommendations. Patients who underwent an abdominal surgery under general anesthesia in the period from January 2017 through December 2020 with a neuromuscular block with rocuronium were included in the study. Data were extracted from the Centricity anesthesia information management system. In total, 2242 patients were assessed: 459 in center 1 (61 having received neostigmine and 398 sugammadex) and 1783 in center 2 (531 and 1252, respectively). Patients' characteristics differed between centers, with more high-risk patients in center 1. The mean train-of-four (TOF) ratio after supramaximal current determination (supramaximal threshold) was higher in center 1 (p < 0.001). Most patients received neostigmine while the TOF ratio was < 40% (68.6% in center 1 and 62.4% in center 2), while extubation was performed while the TOF ratio was > 90% in 61.0% in center 1 and in 32.1% in center 2 (p < 0.001). Patients received sugammadex irrespective of the number of responses to TOF before reversal, and extubation was performed while the TOF ratio was > 90% in 85.0% in center 1 and in 53.6% in center 2 (p < 0.001). No side effect was encountered. Despite guidelines for the TOF ratio before extubation, recommendations were not adequately respected and more vigilance is mandatory. The TOF test before use gave values that were 100% far apart with an underestimation with acceleromyography and an overestimation using kinemyography.</p>","PeriodicalId":15513,"journal":{"name":"Journal of Clinical Monitoring and Computing","volume":" ","pages":"141-148"},"PeriodicalIF":2.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141731249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ASNM intraoperative SSEP position statement. ASNM 术中 SSEP 立场声明。
IF 2 3区 医学
Journal of Clinical Monitoring and Computing Pub Date : 2025-02-01 Epub Date: 2024-09-11 DOI: 10.1007/s10877-024-01213-7
David Allison
{"title":"ASNM intraoperative SSEP position statement.","authors":"David Allison","doi":"10.1007/s10877-024-01213-7","DOIUrl":"10.1007/s10877-024-01213-7","url":null,"abstract":"","PeriodicalId":15513,"journal":{"name":"Journal of Clinical Monitoring and Computing","volume":" ","pages":"257-258"},"PeriodicalIF":2.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142288324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Practical prognostic tools to predict the risk of postoperative delirium in older patients undergoing cardiac surgery: visual and dynamic nomograms. 预测接受心脏手术的老年患者术后谵妄风险的实用预后工具:视觉和动态提名图。
IF 2 3区 医学
Journal of Clinical Monitoring and Computing Pub Date : 2025-02-01 Epub Date: 2024-09-21 DOI: 10.1007/s10877-024-01219-1
Chernor Sulaiman Bah, Bongani Mbambara, Xianhai Xie, Junlin Li, Asha Khatib Iddi, Chen Chen, Hui Jiang, Yue Feng, Yi Zhong, Xinlong Zhang, Huaming Xia, Libo Yan, Yanna Si, Juan Zhang, Jianjun Zou
{"title":"Practical prognostic tools to predict the risk of postoperative delirium in older patients undergoing cardiac surgery: visual and dynamic nomograms.","authors":"Chernor Sulaiman Bah, Bongani Mbambara, Xianhai Xie, Junlin Li, Asha Khatib Iddi, Chen Chen, Hui Jiang, Yue Feng, Yi Zhong, Xinlong Zhang, Huaming Xia, Libo Yan, Yanna Si, Juan Zhang, Jianjun Zou","doi":"10.1007/s10877-024-01219-1","DOIUrl":"10.1007/s10877-024-01219-1","url":null,"abstract":"<p><strong>Purpose: </strong>Postoperative Delirium (POD) has an incidence of up to 65% in older patients undergoing cardiac surgery. We aimed to develop two dynamic nomograms to predict the risk of POD in older patients undergoing cardiac surgery.</p><p><strong>Methods: </strong>This was a single-center retrospective cohort study, which included 531 older patients who underwent cardiac surgery from July 2021 to June 2022 at Nanjing First Hospital, China. Univariable and multivariable logistic regression were used to identify the significant predictors used when constructing the models. We evaluated the performances and accuracy, validated, and estimated the clinical utility and net benefit of the models using the receiver operating characteristic (ROC), the 10-fold cross-validation, and decision curve analysis (DCA).</p><p><strong>Results: </strong>A total of 30% of the patients developed POD, the significant predictors in the preoperative model were ASA ( p < 0.001 OR = 3.220), cerebrovascular disease (p < 0.001 OR = 2.326), Alb (p < 0.037 OR = 0.946), and URE (p < 0.001 OR = 1.137), while for the postoperative model they were ASA (p = 0.044, OR = 1.737), preoperative MMSE score (p = 0.005, OR = 0.782), URE (p = 0.017 OR = 1.092), CPB duration (p < 0.001 OR = 1.010) and APACHE II (p < 0.001, OR = 1.353). The preoperative and postoperative models achieved satisfactory predictive performances, with AUC values of 0.731 and 0.799, respectively. The web calculators can be accessed at https://xxh152.shinyapps.io/Pre-POD/ and https://xxh152.shinyapps.io/Post-POD/ .</p><p><strong>Conclusion: </strong>We established two nomogram models based on the preoperative and postoperative time points to predict POD risk and guide the flexible implementation of possible interventions at different time points.</p>","PeriodicalId":15513,"journal":{"name":"Journal of Clinical Monitoring and Computing","volume":" ","pages":"11-24"},"PeriodicalIF":2.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142288326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Understanding fluid dynamics and renal perfusion in acute kidney injury management. 了解急性肾损伤治疗中的流体动力学和肾灌注。
IF 2 3区 医学
Journal of Clinical Monitoring and Computing Pub Date : 2025-02-01 Epub Date: 2024-08-28 DOI: 10.1007/s10877-024-01209-3
Antonio Messina, Marta Calatroni, Gianluca Castellani, Silvia De Rosa, Marlies Ostermann, Maurizio Cecconi
{"title":"Understanding fluid dynamics and renal perfusion in acute kidney injury management.","authors":"Antonio Messina, Marta Calatroni, Gianluca Castellani, Silvia De Rosa, Marlies Ostermann, Maurizio Cecconi","doi":"10.1007/s10877-024-01209-3","DOIUrl":"10.1007/s10877-024-01209-3","url":null,"abstract":"<p><p>Acute kidney injury (AKI) is associated with an increased risk of morbidity, mortality, and healthcare expenditure, posing a major challenge in clinical practice, and affecting about 50% of patients in the intensive care unit (ICU), particularly the elderly and those with pre-existing chronic comorbidities. In health, intra-renal blood flow is maintained and auto-regulated within a wide range of renal perfusion pressures (60-100 mmHg), mediated predominantly through changes in pre-glomerular vascular tone of the afferent arteriole in response to changes of the intratubular NaCl concentration, i.e. tubuloglomerular feedback. Several neurohormonal processes contribute to regulation of the renal microcirculation, including the sympathetic nervous system, vasodilators such as nitric oxide and prostaglandin E2, and vasoconstrictors such as endothelin, angiotensin II and adenosine. The most common risk factors for AKI include volume depletion, haemodynamic instability, inflammation, nephrotoxic exposure and mitochondrial dysfunction. Fluid management is an essential component of AKI prevention and management. While traditional approaches emphasize fluid resuscitation to ensure renal perfusion, recent evidence urges caution against excessive fluid administration, given AKI patients' susceptibility to volume overload. This review examines the main characteristics of AKI in ICU patients and provides guidance on fluid management, use of biomarkers, and pharmacological strategies.</p>","PeriodicalId":15513,"journal":{"name":"Journal of Clinical Monitoring and Computing","volume":" ","pages":"73-83"},"PeriodicalIF":2.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142093219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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