Mohammed M. Kassem, A. Tammam, W. M. Attia, Mohammed E. Sarhan
{"title":"T Peak-to-T End/QT is an Independent Predictor of Early Ventricular Arrhythmias and Arrhythmic Death in Patients with ST Segment Elevation Myocardial Infarction","authors":"Mohammed M. Kassem, A. Tammam, W. M. Attia, Mohammed E. Sarhan","doi":"10.4172/2155-9880.1000607","DOIUrl":"https://doi.org/10.4172/2155-9880.1000607","url":null,"abstract":"","PeriodicalId":15504,"journal":{"name":"Journal of Clinical and Experimental Cardiology","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87162282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Kim, Tae-Woo Nam, Hyun-Min Oh, Eunhee Park, J. Huh, Won-Jong Yang, D. Yang, H. Park, Yang-Soo Lee, T. Jung
{"title":"Effect of Hospital-based Cardiac Rehabilitation on Quality of Life and Physical Capacity in Acute Myocardial Infarction Patients: 2 Years Follow Up","authors":"A. Kim, Tae-Woo Nam, Hyun-Min Oh, Eunhee Park, J. Huh, Won-Jong Yang, D. Yang, H. Park, Yang-Soo Lee, T. Jung","doi":"10.4172/2155-9880.1000573","DOIUrl":"https://doi.org/10.4172/2155-9880.1000573","url":null,"abstract":"Objective: The aim of this study was to investigate the effect of hospital-based cardiac rehabilitation (CR) on quality of life (QOL) and physical functions in patients with acute myocardial infarction (AMI) during 2 years of followup. Methods: All AMI patients referred to the Cardiac Health and Rehabilitation Center (CHRC) were informed about CR and followed for 2 years on an outpatient basis from July 2010 to December 2015. Patients who were divided into a CR group and non-CR group. All patients took home-based self-exercise as CR programs of CHRC and in addition, the CR group received hospital-based supervised exercise training three times a week for 2 months. Both groups were evaluated for physical capacity and QOL at baseline, after 2 months of exercise training, and at 6 months, 1 year, and 2 years of follow-up. Results: The CR group showed significant improvements in physical functioning (PF), physical role functioning, bodily pain, vitality (VT), social role functioning, emotional role functioning, mental health, physical component summary (PCS), and mental component summary at all-time points compared to baseline. At 1 year of follow-up, the CR group displayed significantly greater PF, general health perceptions, VT, and PCS values than the non-CR group. Regarding physical capacity, the CR group exhibited significantly lower resting heart rate and significantly greater maximal oxygen consumption and metabolic equivalents than the non-CR group at 6 months of follow-up. Conclusion: Hospital-based CR was effective in promoting QOL and early improvement in exercise capacity in patients with AMI. Further, the improvement in QOL was maintained for up to 2 years.","PeriodicalId":15504,"journal":{"name":"Journal of Clinical and Experimental Cardiology","volume":"69 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90242914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Registry of Patients with Suspected Myocarditis: Diagnosing Edema using STIR+ via 3-D-Cardiovascular Magnetic Resonance Imaging-Real World Experience","authors":"M. Jeserich, S. Kimmel, S. Achenbach","doi":"10.4172/2155-9880.1000608","DOIUrl":"https://doi.org/10.4172/2155-9880.1000608","url":null,"abstract":"","PeriodicalId":15504,"journal":{"name":"Journal of Clinical and Experimental Cardiology","volume":"103 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78250139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Energy Sources at Peak All-out Exercise in Adolescents and Young Adults","authors":"M. Saghiv, D. Sira, E. Goldhammer, Jill K. Nustad","doi":"10.4172/2155-9880.1000579","DOIUrl":"https://doi.org/10.4172/2155-9880.1000579","url":null,"abstract":"Purpose: To examine the aerobic energy portion utilized during the Wingate Anaerobic Test. Methods: Power output was compared with direct values obtained from measured oxygen uptake (VO2), in 14 (14.4 ± 1.0 yrs) healthy adolescents and 14 young adults (26.0 ± 1.0 yrs). Results: All subjects completed the exercise challenges without ECG abnormality. At rest, significant (P<0.05) differences were noted between the groups in heart rate, and diastolic blood pressure. At peak exercise, significant (P<0.05) differences were noted between adolescents and young subjects for oxygen uptake (21.5 ± 0.3 vs. 18.3 ± 0.3 mLO2 × kg-1 × min-1 respectively), power output for 30 s (0.63 ± 0.3 vs. 0.78 ± 0.3 LO2 × min-1/2 respectively), aerobic energy portion utilized (40.7 ± 4.7 vs. 17.7 ± 3.2 % respectively) and lactic acid (8.5 ± 0.7 and 12.6 ± 1.1 mmol × L-1 respectively). In addition, differences were seen in heart rate, systolic blood pressure, diastolic blood pressure, and mean arterial blood pressure. Conclusions: The results reflect a significant noticeably lower anaerobic power output during adolescence, which suggests that glycolytic activity is age-dependent. This may be related to different muscle substrate, enzyme activity and differences in phosphorus compounds between fast and slow fiber types. As a result, adolescents relied more on oxidative metabolism compared to young adults.","PeriodicalId":15504,"journal":{"name":"Journal of Clinical and Experimental Cardiology","volume":"33 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77970339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Uses of Postextrasystolic Potentiation (PESP): The Actual and Hypothetical","authors":"M. W. Cooper","doi":"10.4172/2155-9880.1000604","DOIUrl":"https://doi.org/10.4172/2155-9880.1000604","url":null,"abstract":"","PeriodicalId":15504,"journal":{"name":"Journal of Clinical and Experimental Cardiology","volume":"70 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75741805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Effect of Long Term Smoking as an Independent Coronary Risk Factor on Myocardial Perfusion Detected by Thallium 201 or Tc99m Sestamibi Spect Study","authors":"Samir M Rafla, A. Abdel-Aaty, M. Lotfy, R. Gamal","doi":"10.4172/2155-9880.1000589","DOIUrl":"https://doi.org/10.4172/2155-9880.1000589","url":null,"abstract":"Objective: The aim of this work was to assess the effect of smoking as an independent coronary risk factor on Myocardial Perfusion detected by Thallium 201 or Tc99m Sesta MIBI SPECT study.Methods: This study included 200 patients, 100 who are smokers only (group A) without any cardiac risks and the other 100 (group B) were nonsmokers, but with single cardiac risk factor as hypertension or diabetes. Each was subjected to Dipyridamole (smokers 53, 47) or exercise (nonsmokers 51, 49) Thallium-201 or Tc99m SestaMIBI SPECT protocol.Results: Comparing smokers versus nonsmokers who have another one risk factor, smokers had : Lower age with ischemic heart disease 55 years versus 60 years; Higher heart rate during peak stress; higher blood pressure during peak stress; More incidence of chest pain during stress test; had the same degree of ischemic perfusion defect, but higher incidence of persistent LV dilatation (43% versus 28%), higher incidence of severe perfusion defects (68% versus 53%) and statistically significant higher incidence of scar tissue (52% versus 30%).Conclusion: Smoking is an independent risk factor equal to hypertension and diabetes but smokers has higher incidence of severe perfusion defects and scar.","PeriodicalId":15504,"journal":{"name":"Journal of Clinical and Experimental Cardiology","volume":"43 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74215879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Droghetti, S. Branzoli, P. Moggio, G. Belotti, S. Valsecchi, A. Coser, F. Guarracini, S. Quintarelli, C. Pederzolli, A. Graffigna, R. Bonmassari, C. Pomarolli, G. Molon, Maria Caterina Bottoli, M. Centonze, M. Campari, M. Marini
{"title":"Minimally Invasive Thoracoscopic Technique for LV Lead Implantation in CRT Patients","authors":"A. Droghetti, S. Branzoli, P. Moggio, G. Belotti, S. Valsecchi, A. Coser, F. Guarracini, S. Quintarelli, C. Pederzolli, A. Graffigna, R. Bonmassari, C. Pomarolli, G. Molon, Maria Caterina Bottoli, M. Centonze, M. Campari, M. Marini","doi":"10.4172/2155-9880.1000575","DOIUrl":"https://doi.org/10.4172/2155-9880.1000575","url":null,"abstract":"Background: Epicardial placement of the left ventricular (LV) lead is an alternative approach to the standard cardiac resynchronization therapy (CRT) procedure. In our center we developed a minimally invasive thoracoscopic technique. We reviewed our experience to evaluate the long-term safety and effectiveness of the technique. Methods: The procedure is performed under general anesthesia with oro-tracheal intubation and right-sided ventilation, and requires 3 thoracoscopic ports (two 5-mm and one 15-mm). We analyzed 94 consecutive patients referred to our center for epicardial LV lead implantation. Results: Five patients were excluded because of concomitant conditions precluding surgery or lack of indication for CRT. The remaining 89 patients underwent the procedure. Of these, 57 had undergone previous unsuccessful LV lead implantation (Group 1). In the remaining 32 patients, effective CRT was discontinued owing to LV lead dislodgment (Group 2). LV lead implantation was successful in all patients (median pacing threshold 0.8V, IQR: 0.6-1.2, at 0.5 ms, no phrenic nerve stimulation) and CRT was successfully established in all but one patient. No complications were reported, except for 2 cases of transitory peri-electrode bleeding and 3 cases of ventricular fibrillation induced during the procedure (no sequelae). The median procedure time was 75 min (IQR: 55-95). During a median follow-up of 24 [IQR: 13-39] months, 21 patients died and 4 additional device-related complications were reported (comparable rates between groups). Conclusions: Our thoracoscopic approach proved to be safe and effective. It is a viable alternative to the standard transvenous approach in the case of failed de novo implantation and in those patients who positively respond to CRT but experience LV lead dislodgment.","PeriodicalId":15504,"journal":{"name":"Journal of Clinical and Experimental Cardiology","volume":"194 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83091017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A New Total Artificial Heart Concept Allowing Replacement or Support of the Native Heart","authors":"H. Ahn, J. Holm, A. Najar, G. Hellers, Z. Szabó","doi":"10.4172/2155-9880.1000569","DOIUrl":"https://doi.org/10.4172/2155-9880.1000569","url":null,"abstract":"A total artificial heart (TAH) is typically used to bridge the time to heart transplantation. A device designed by Robert Jarvik has been improved through the years and under the name of Syncardia™ this has been the most successful commercially available TAH so far. Since 2008 the Carmat™ heart has been under development in Europe. The Scandinavian Real Heart™ is based on a unique physiological concept where the atrio-ventricular valve plane is of utmost importance in the pumping function of the heart. It consists of two identical parts driven separately by independent motors and in this first animal study we have used one part as a left ventricular assist device. This new concept makes the device flexible as it may be used not only as a TAH but also as a separate pump for left or right ventricular assist.","PeriodicalId":15504,"journal":{"name":"Journal of Clinical and Experimental Cardiology","volume":"19 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79926451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abdelrahman M. Yassin, Gomaa Abdelrazek, Randa A.Soliman, Khalid A. Elkhashab, S. Zaky
{"title":"Role of Tissue Doppler Tei Index in Evaluating Myocardial Performance after Coronary Revascularization","authors":"Abdelrahman M. Yassin, Gomaa Abdelrazek, Randa A.Soliman, Khalid A. Elkhashab, S. Zaky","doi":"10.4172/2155-9880.1000590","DOIUrl":"https://doi.org/10.4172/2155-9880.1000590","url":null,"abstract":"Background: Tei index expresses the overall systolic and diastolic myocardial function in a single number. The use of tissue Doppler instead of conventional pulsed wave Doppler enables us to measure Tei index in a single scan. It also has many advantages for the assessment of myocardial function with coronary revascularization in IHD patients. Methods: We included 47 chronic ischemic heart disease patients with LV dysfunction (EF<50%) who were subjected to coronary revascularization with either CABG or PCI. They were divided into 2 groups according to the improvement of EF after revascularization. Group I: Included 35 patients who had an increase ≥ 5% in LV EF at follow up. Group II: Included 12 patients who had an increase <5% increase in LV EF at follow up. Echocardiography including tissue Doppler Tei index (tdTei) was done twice; just before and at least 4 months after coronary revascularization. Results: Following revascularization; improvement of ejection fraction correlated well with tdTei improvement (r=0.67, p<0.001) and was associated with improvement of wall motion score index (p<0.001) and diastolic function parameters including E`/A` (p<0.05) and E/E` (p<0.001). Using ROC curve, we found that the tdTei index at cut-off point 72.9; can predict patients who are expected to have ejection fraction improvement from coronary revascularization with high sensitivity (83.3%) and specifity (80%). It also correlated well to TIMI score (p<0.05). Conclusion: Tissue Doppler Tei index is a promising technique allowing accurate quantitative description of the effect of ischemia on myocardium including both diastolic and systolic dysfunction in a single number. Baseline tdTei index can predict patients who are expected to have improvement of myocardial function (both diastolic and systolic) after coronary revascularization.","PeriodicalId":15504,"journal":{"name":"Journal of Clinical and Experimental Cardiology","volume":"43 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89350045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Heart Rate Variability (HRV)","authors":"K. R. Panday, D. Panday","doi":"10.4172/2155-9880.1000583","DOIUrl":"https://doi.org/10.4172/2155-9880.1000583","url":null,"abstract":"Heart rate is mainly determined by pacemaker current generated in the SA node. It, in turn, is regulated by autonomic nervous system. Sympathetic stimulation enhances chronotropic, ionotropic and dromotropic activity via α and β receptor activation whereas, parasympathetic stimulation causes reverse effect on heart via the M2 receptors. Varied input from these two branches of the ANS produces change in heart rate. So, HRV, therefore, is the change in the time interval between two consecutive heartbeats. In other words, HRV is the time difference between a given heart beat to the mean duration of heartbeat. Like all other organs of the body, heart is also susceptible to aging and diseases. These conditions influence heart rate and also HRV. Today, HRV has invited much investigation and debate. Electronic databases Google Scholar, IMSEAR (Index Medicus for South-East Asia Region), Scopemed and MEDLINE/PubMed were extensively explored with key words “HRV” or “Heart Rate Variability” from earliest possible date (1973) to December, 2016 and the available information summarized. Different aspects of HRV have been covered including historical background, HRV Analysis Methods, Interpretation of HRV, software’s used for HRV recording, importance of HRV measurement, HRV in varying conditions, drugs etc. HRV offers a relatively simple, well-tolerated, and inexpensive method for studying physiological and pathophysiological processes in a noninvasive manner. However, there are several important challenges in this area of study. There are a number of confounding variables which contribute to HRV data collection and interpretation open to question. Again, one should not compare one’s HRV with others, since HRV is affected by numerous internal and external factors, namely, age, lifestyle, hormones, body functions etc.","PeriodicalId":15504,"journal":{"name":"Journal of Clinical and Experimental Cardiology","volume":"42 1","pages":"1-12"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75854741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}