Journal of Clinical Neuroscience最新文献

{"title":"Global improvement after deep brain stimulation in Parkinson’s disease: Comparison between patient and clinician perspectives","authors":"Pietro Antenucci ,&nbsp;Fabiana Colucci ,&nbsp;Andrea Gozzi ,&nbsp;Alba Scerrati ,&nbsp;Michele Alessandro Cavallo ,&nbsp;Jay Guido Capone ,&nbsp;Maura Pugliatti ,&nbsp;Mariachiara Sensi","doi":"10.1016/j.jocn.2025.111323","DOIUrl":"10.1016/j.jocn.2025.111323","url":null,"abstract":"<div><h3>Background</h3><div>The definition of improvement after Deep Brain Stimulation (DBS) in Parkinson’s Disease (PD) remains unclear. The neurologist’s perspective, based on measurable parameters, may differ from the patient’s perception, and both are crucial for therapeutic success. Whether clinical variables influence these differences is unknown.</div></div><div><h3>Objective</h3><div>To compare the correlation between clinician-assessed (Clinical Global Impression of Improvement, CGI) and patient-reported (Patient Global Impression of Change, PGIC) improvement after DBS and identify factors affecting variability.</div></div><div><h3>Methods</h3><div>We included DBS patients treated at Ferrara Hospital (2006–2022) with ≥ 1-year follow-up. CGI and PGIC were collected at that time, and their correlation analyzed across clinical and demographic subgroups.</div></div><div><h3>Results</h3><div>Among 51 PD patients, CGI rated 21 as “very much improved,” 21 “much improved,” and 9 “minimally improved,” primarily based on MDS-UPDRS III reduction. Agreement with PGIC was 0.65 (p &lt; 0.001), unaffected by age, gender, disease duration, IPG type, LEDD, medication count, MDS-UPDRS III improvement, or stimulation-induced complications. Concordance was weaker (k &lt; 0.60) in patients with higher baseline MDS-UPDRS III, lower MDS-UPDRS IV, less MDS-UPDRS IV improvement, greater tablet reduction, and fewer outpatient visits. It was stronger (k &gt; 0.70) with more follow-ups in the first year.</div></div><div><h3>Conclusion</h3><div>Clinician-patient agreement on DBS improvement is moderate, with motor symptom amelioration only partially reflecting patients’ overall perceived improvement. Various factors widen the gap of concordance, particularly in patients with subtle improvement according to clinicians, while more follow-ups due to stimulation management enhance it. Clinicians must consider that their perspectives may only partially mirror those of the patient during DBS treatment.</div></div>","PeriodicalId":15487,"journal":{"name":"Journal of Clinical Neuroscience","volume":"137 ","pages":"Article 111323"},"PeriodicalIF":1.9,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143936249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Upper extremity transvenous access in neurointerventional procedures: Insights from the largest single-center experience","authors":"Mikaeel A. Habib ,&nbsp;Luis O. Tierradentro-Garcia ,&nbsp;Robert Romano ,&nbsp;Suehyb G. Alkhatib ,&nbsp;Jaeha Kim ,&nbsp;Aarush Sahni ,&nbsp;Aaron T. Zhao ,&nbsp;Jason A. Brant ,&nbsp;Douglas C. Bigelow ,&nbsp;Tiffany Hwa ,&nbsp;Michael J. Ruckenstein ,&nbsp;Omar A. Choudhri","doi":"10.1016/j.jocn.2025.111325","DOIUrl":"10.1016/j.jocn.2025.111325","url":null,"abstract":"<div><h3>Background</h3><div>The transfemoral approach has traditionally been the primary access site for catheter-guided venography. Recently, upper extremity transvenous access (UETV) has emerged as a promising alternative for neurointerventional procedures, offering potential advantages such as reduced bleeding risk, improved ergonomics, faster recovery, shorter procedure and fluoroscopy times, and a lower likelihood of inadvertent arterial puncture. This study reports on a single-center experience of UETV for neurointerventional venous therapy.</div></div><div><h3>Methods</h3><div>A total of 158 diagnostic venograms and venous interventions were performed by a single operator between 2020 and 2024 at a single center, with primary intent to use the upper extremity veins for venous access. Data on patient demographics, procedural details, radiographic findings, and outcomes were collected and analyzed.</div></div><div><h3>Results</h3><div>Out of 158 procedures, successful upper extremity catheterization was achieved in 155 cases (98.1%), with 149 (94.3%) completed successfully. Conversion to a femoral approach was necessary in 3 cases (1.9%), all of which were completed successfully. Six interventions (3.8%) were aborted due to challenges in navigating the intracranial veins and venous sinuses that were unrelated to peripheral access. Minor complications occurred in 8 patients (5.1%); no major complications were observed.</div></div><div><h3>Conclusions</h3><div>This single-center study demonstrates the feasibility and safety of upper extremity-only transvenous access for neurointerventional procedures in the management of complex cerebrovascular diseases. The cephalic and basilic veins of the antecubital fossa veins are recommended as primary access sites. These findings represent the largest case series to date using an upper extremity-first transvenous approach for neurointerventional therapy.</div></div>","PeriodicalId":15487,"journal":{"name":"Journal of Clinical Neuroscience","volume":"137 ","pages":"Article 111325"},"PeriodicalIF":1.9,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143936247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sonographically measured optic nerve sheath diameter as a predictor of stroke severity and outcome among Ghanaian acute stroke patients","authors":"Priscilla Abrafi Opare-Addo ,&nbsp;Minas Aikins ,&nbsp;Kenneth Ampoful ,&nbsp;Sefakor Adinyira ,&nbsp;Alfred Kobi ,&nbsp;Webster Donaldy ,&nbsp;Kwadwo Faka Gyan ,&nbsp;Collins Kokuro ,&nbsp;Fred Stephen Sarfo","doi":"10.1016/j.jocn.2025.111322","DOIUrl":"10.1016/j.jocn.2025.111322","url":null,"abstract":"<div><h3>Background</h3><div>Elevated intracranial pressure (ICP) is a veritable and potentially modifiable predictor of adverse stroke outcome. Sonographically measured optic nerve sheath diameter (ONSD), a non-invasive proxy for ICP, could potentially be utilized as an objective measure of severity and outcome among acute stroke patients.</div></div><div><h3>Objective</h3><div>To evaluate the relationship between admission ONSD, stroke severity, and functional outcomes among patients with acute stroke.</div></div><div><h3>Methods</h3><div>A prospective cohort study was conducted among patients with neuroimaging-confirmed acute strokes admitted to a tertiary hospital in Ghana. The ONSD of each patient was measured within 24 h of admission. Multivariable linear regression was conducted to determine the relationship between admission ONSDs, Glasgow Coma score (GCS), and modified Rankin Score (mRS) at days 30, 60, and 90.</div></div><div><h3>Results</h3><div>We enrolled 116 patients comprising 69 ischaemic strokes, mean (SD) age 62.6 years ± 12.8 versus 47 hemorrhagic strokes, aged 50.9 years ± 12.2 years (p = 0.000). Presence of neuroimaging features of raised ICP was associated with elevated admission ONSD (β 1.253 (95 % CI: 0.229–2.277), p = 0.017). A higher<!--> <!-->admission ONSD was an independent predictor of lower<!--> <!-->Glasgow Coma score<!--> <!-->in individuals with ischemic strokes (adjusted β −8.602 (95 % CI −16.077- −1.127), p = 0.025) but not hemorrhagic strokes. For individuals with hemorrhagic strokes, higher admission ONSD was an independent predictor of month 1 mRS (β 5.363 (95 % CI 0.804–9.922), p = 0.022) and month 2 mRS (β 10.546 (95 % CI 0.595–20.498), p = 0.039). However, for ischemic strokes, elevated<!--> <!-->admission<!--> <!-->ONSD was an independent predictor of mRS at month 2 (β 16.501 (95 % CI 5.202–27.800), p = 0.005) and month 3(β 16.643 (95 % CI 3.666–29.620), p = 0.014).</div></div><div><h3>Conclusion</h3><div>Sonographically determined ONSD is an independent predictor of stroke severity and functional outcomes in this Ghanaian cohort. Randomized control trials exploring the potential role of ONSD in guiding clinical decisions during acute stroke management are warranted, especially in resource-limited settings.</div></div>","PeriodicalId":15487,"journal":{"name":"Journal of Clinical Neuroscience","volume":"137 ","pages":"Article 111322"},"PeriodicalIF":1.9,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143936246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative efficacy of tranexamic acid in aneurysmal subarachnoid hemorrhage: A network meta-analysis on rebleeding, mortality, and hydrocephalus","authors":"Arkansh Sharma ,&nbsp;Rishu Raj ,&nbsp;Vinay Suresh","doi":"10.1016/j.jocn.2025.111303","DOIUrl":"10.1016/j.jocn.2025.111303","url":null,"abstract":"","PeriodicalId":15487,"journal":{"name":"Journal of Clinical Neuroscience","volume":"137 ","pages":"Article 111303"},"PeriodicalIF":1.9,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143935464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Positive association of neck pain and depression in American young adults :A cross-sectional study","authors":"Jiqiang Zhu ,&nbsp;Xianfeng Li ,&nbsp;Xiaoyu Wang ,&nbsp;Fei Yang ,&nbsp;Qing Wang ,&nbsp;Jing Lu","doi":"10.1016/j.jocn.2025.111315","DOIUrl":"10.1016/j.jocn.2025.111315","url":null,"abstract":"<div><h3>Background</h3><div>At present, the available evidence regarding the relationship between neck pain and depression is inadequate. We investigated the detailed association between neck pain and depression among American young adults.</div></div><div><h3>Methods</h3><div>In this cross-sectional study, 1,949 young adults were selected from the National Health and Nutrition Examination Survey 1999–2004 for the sample. For the assessment of neck pain and depression, we used a questionnaire about miscellaneous pain and mental health from personal interview data, defining neck pain as those who have had neck pain in the past three months, and defining depression as those who positive depression score. Logistic regression were utilized to substantiate the research objectives. A subgroup analysis was carried out to ensure that the results were stable.</div></div><div><h3>Results</h3><div>This study included a total of 1,949 eligible participants, 344 reported neck pain, with a prevalence of 17.7 %. Depression was reported in 133 cases, indicating a prevalence rate of 6.8 %. Patients with neck pain were significantly more likely to have depression (11.6 %) than those without it (5.8 %, p &lt; 0.001). After adjusting for age, sex, race/ethnicity, education level, marital status, family income, physical activity, smoking, alcohol consumption, hypertension, diabetes, and oral analgesics, neck pain is significantly associated with depression (OR: 1.72, 95 %CI: 1.14–2.6, p = 0.01). Subgroup analyses by age, sex, smoking, alcohol, and oral analgesics showed no statistically significant interactions (p &gt; 0.05).</div></div><div><h3>Conclusion</h3><div>In summary, the findings of this research indicated a significant link between neck pain and depression. Clinicians should screen and assess for depression in patients experiencing neck pain, ensuring that they offer prompt and effective interventions to prevent further exacerbation of the condition.</div></div>","PeriodicalId":15487,"journal":{"name":"Journal of Clinical Neuroscience","volume":"137 ","pages":"Article 111315"},"PeriodicalIF":1.9,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143936248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adjunct middle meningeal artery embolization versus surgery alone for chronic subdural hematoma: A meta-analysis and trial sequential analysis of randomized controlled trials","authors":"João Pedro Fernandes Gonçalves,&nbsp;Gabriel Souza Medrado-Nunes,&nbsp;Gabriel Teles de Oliveira Piñeiro,&nbsp;Felipe Asaf Borges Millard,&nbsp;Marcos Paulo Rodrigues Oliveira,&nbsp;Nara Samara Silva Felipe dos Santos,&nbsp;Thaís Barbosa de Oliveira,&nbsp;Pedro Henrique Ferreira Sandes,&nbsp;Luiz Paulo Oliveira-Martins,&nbsp;Marivaldo Yslan Silveira-Leal,&nbsp;Júlia Xavier,&nbsp;Luísa Dias Moreno Aravena,&nbsp;Pedro Antonio Pereira de Jesus","doi":"10.1016/j.jocn.2025.111307","DOIUrl":"10.1016/j.jocn.2025.111307","url":null,"abstract":"<div><h3>Introduction</h3><div>Middle meningeal artery embolization (MMAE) has been studied as an adjunct to surgical evacuation for chronic subdural hematoma (cSDH). Previous <em>meta</em>-analyses comparing MMAE with conventional treatment for cSDH included both observational and randomized studies. To provide a more robust assessment, we performed a <em>meta</em>-analysis of randomized controlled trials to evaluate the outcomes of adjunct MMAE compared to surgical treatment alone.</div></div><div><h3>Methods</h3><div>We searched PubMed, EMBASE, and Cochrane CENTRAL databases for studies comparing adjunct middle meningeal artery embolization to surgical treatment alone until December 2024. The outcomes assessed were treatment failure, reoperation, complications, mortality, functional outcome, and length of hospital stay. Statistical analysis was performed via R software (version 4.3.2). Heterogeneity was assessed with I² statistics. The risk of bias was assessed using the Cochrane Risk of Bias Tool for Randomized Trials.</div></div><div><h3>Results</h3><div>We included 6 studies with 1,422 patients, of whom 700 (49.2 %) received adjunct middle meningeal artery embolization. The mean age ranged from 64.2 to 77.4 years in the embolization group and from 70 to 74.4 years in the surgery-only group. Among the patients, 435 (54.5 %) had previous known head trauma, and 315 (22.1 %) were on antiplatelets or anticoagulants. The follow-up ranged from 90 to 180 days. Adjunct middle meningeal artery embolization reduced the occurrence of treatment failure compared to surgical treatment alone (RR 0.482; 95 % CI 0.328 to 0.708; p &lt; 0.001; I² = 0 %) and reoperation (RR 0.333; 95 % CI 0.212 to 0.521; p &lt; 0.001; I² = 0 %), however, didńt reduce the occurrence of any cause mortality (RR 0.970; 95 % CI 0.400 to 2.353; p = 0.946; I² = 39.6 %), functional dependence at the last follow-up (RR 1.000; 95 % CI 0.726 to 1.377; p = 0.705; I² = 0 %), or the length of stay (MD 0.576; 95 % CI −0.085 to 1.238; p = 0.088; I² = 0 %). Furthermore, no differences were found regarding complications secondary to the surgical procedure (RR 0.902; 95 % CI 0.688 to 1.182; p = 0.455; I² = 0 %), and the occurrence of embolization-related complication was low (RR 0.013; 95 % CI 0.006 to 0.027; I² = 0 %). Trial sequential analysis judged the sample size sufficient for treatment failure and reoperation but suggested that further trials are needed to prove differences in surgical-related complications.</div></div><div><h3>Conclusion</h3><div>Our results confirm that middle meningeal artery embolization significantly reduces recurrence and reoperation rates compared to surgery alone, with low adverse event rates. However, the impact on functional outcomes and mortality remains uncertain, warranting further studies to clarify its long-term benefits.</div></div>","PeriodicalId":15487,"journal":{"name":"Journal of Clinical Neuroscience","volume":"137 ","pages":"Article 111307"},"PeriodicalIF":1.9,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143935465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Posterior fixation for pyogenic spondylitis following osteoporotic vertebral fracture: A retrospective study of five challenging cases","authors":"Yosuke Ogata,&nbsp;Hisanori Gamada,&nbsp;Toru Funayama,&nbsp;Yusuke Setojima,&nbsp;Takane Nakagawa,&nbsp;Takahiro Sunami,&nbsp;Kotaro Sakashita,&nbsp;Shun Okuwaki,&nbsp;Kousei Miura,&nbsp;Hiroshi Noguchi,&nbsp;Hiroshi Takahashi,&nbsp;Masao Koda","doi":"10.1016/j.jocn.2025.111295","DOIUrl":"10.1016/j.jocn.2025.111295","url":null,"abstract":"<div><h3>Background</h3><div>Pyogenic spondylitis following osteoporotic vertebral fracture is rare but serious with a poor clinical outcome. Although posterior fixation is an effective treatment for pyogenic spondylitis, surgical outcomes following osteoporotic vertebral fractures remain largely unreported. We present the outcomes of five challenging cases treated with posterior fixation.</div></div><div><h3>Methods</h3><div>We retrospectively evaluated patients who underwent posterior fixation for pyogenic spondylitis between January 2021 and July 2023. Five patients with pyogenic spondylitis following osteoporotic vertebral fracture were identified. We examined the age, sex, location of the vertebral fracture and infection, time from fracture to infection diagnosis, C-reactive protein levels, causative organisms, antibiotic therapy, operative procedures, and clinical outcomes.</div></div><div><h3>Results</h3><div>Three male and two female patients were included; they had a mean age of 75.4 years (standard deviation [SD], 7.1; range, 65–83 years). The mean time from fracture to diagnosis was 37.0 days (SD, 15.9; range, 21–55 days). All causative organisms were identified. Initial posterior fixation proved insufficient in four of the five patients, and additional surgery was required. The remaining patient developed significant screw backout. Additional procedures included fixation extension, anterior vertebral replacement, and fibular strut grafting. Infection control was achieved in all patients, and the mean follow-up duration was 20.4 months (SD, 9.9; range, 15–38 months).</div></div><div><h3>Conclusions</h3><div>We encountered five patients in whom posterior fixation alone proved insufficient for treating pyogenic spondylitis following osteoporotic vertebral fracture. Treatment strategies for this condition should address both infection control and spinal reconstruction, incorporating anterior column support and posterior fixation techniques.</div></div>","PeriodicalId":15487,"journal":{"name":"Journal of Clinical Neuroscience","volume":"137 ","pages":"Article 111295"},"PeriodicalIF":1.9,"publicationDate":"2025-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143928978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is Supplemented Spetzler-Martin grading Superior? A comparative study in AVM microsurgery risk stratification","authors":"Cyrus Raki ,&nbsp;Chris Xenos ,&nbsp;Leon T. Lai","doi":"10.1016/j.jocn.2025.111311","DOIUrl":"10.1016/j.jocn.2025.111311","url":null,"abstract":"<div><div>The Spetzler-Martin (SM) grading system remains the most widely adopted classification for brain arteriovenous malformations (AVMs). The Supplemented Spetzler-Martin (Supp-SM) system was developed to improve surgical risk stratification by incorporating patient age, rupture status, and nidus diffuseness. However, data comparing its predictive validity remain limited. This study investigates the predictive relevance of SM and Supp-SM grading for postoperative neurological morbidity following AVM microsurgery at a single tertiary cerebrovascular centre.</div><div>A retrospective review identified 96 patients who underwent AVM microsurgical resection, with or without preoperative embolisation, between 2015 and 2024. Postoperative morbidity was defined as worsened modified Rankin Scale (mRS) score at 90 days. Predictive accuracy was analysed using ROC curves, correlation with postoperative mRS scores, and Supp-SM risk threshold.</div><div>Postoperative morbidity occurred in 9 patients (9.4 %). ROC analysis revealed no significant difference between SM (AUROC 0.717; 95 % CI 0.55–0.88) and Supp-SM (AUROC 0.667; 95 % CI 0.46–0.88) scores, p = 0.3899. However, Supp-SM scores demonstrated a stronger correlation with postoperative mRS changes (Spearman’s ρ = 0.269, p = 0.008) than SM grades (Spearman’s ρ = 0.144, p = 0.161). Patients with Supp-SM grades &lt; 6 had a 3.2 % morbidity risk, compared with a 20.6 % risk for scores ≥ 6 (p = 0.009). A Supp-SM threshold of 6 demonstrated the highest discriminative accuracy in differentiating high- and low-risk surgical candidates.</div><div>While no significant predictive difference was found between SM and Supp-SM grading, a Supp-SM score of ≥ 6 was associated with substantially higher morbidity. These findings support the adjunctive use of Supp-SM grading for surgical risk assessment in AVM patients.</div></div>","PeriodicalId":15487,"journal":{"name":"Journal of Clinical Neuroscience","volume":"137 ","pages":"Article 111311"},"PeriodicalIF":1.9,"publicationDate":"2025-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143929444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Invasive surgical management of cervical internal jugular venous compression: A literature review","authors":"Gayani Petersingham ,&nbsp;Nipun Shrestha ,&nbsp;Michael Elliott ,&nbsp;Rodney S. Allan ,&nbsp;Geoffrey Parker ,&nbsp;Louise Van Camp ,&nbsp;Prashanth J. Rao","doi":"10.1016/j.jocn.2025.111304","DOIUrl":"10.1016/j.jocn.2025.111304","url":null,"abstract":"<div><h3>Background</h3><div>Internal jugular vein (IJV) compression is associated with several central nervous system symptoms, including but not limited to headache, blurred vision, tinnitus, and brain fog. Cranial venous compression is generally treated with stenting; however, the management of cervical IJV compression is not standardised, and there is very limited published data on outcomes. The objective of this review is to assess the current surgical interventions used in patients with cervical IJV compression and their outcomes.</div></div><div><h3>Methods</h3><div>We performed a literature search on electronic databases for original articles studying surgical interventions for cervical IJV compression. All studies, regardless of patient population or study type, were included.</div></div><div><h3>Results</h3><div>All studies that included at least one case in which a surgical intervention was used to treat cervical IJV compression were considered. Selection criteria had to clearly identify the compression of the IJV in the cervical region. The 14 studies included in this review ranged from case reports to small, single-center cohort studies. Complications were recorded in five studies analysed. Outcome measures varied, but all studies documented the clinical symptoms of the patients.</div></div><div><h3>Conclusion</h3><div>There is a lack of current large cohort studies or clinical trials analysing surgical interventions for patients with cervical IJV compression. The most common surgical intervention is styloidectomy. By understanding the trends and results of interventions previously performed by ENT and Neurosurgeons, more focused and larger studies can be conducted to determine effective strategies that yield the best clinical outcomes.</div></div>","PeriodicalId":15487,"journal":{"name":"Journal of Clinical Neuroscience","volume":"137 ","pages":"Article 111304"},"PeriodicalIF":1.9,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143928976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes in cervical sagittal parameters and the impact on axial symptoms after two types of posterior single-door cervical decompression surgeries","authors":"Zehua Jiang,&nbsp;Xuanhao Fu,&nbsp;Wenjun Du,&nbsp;Rusen Zhu","doi":"10.1016/j.jocn.2025.111293","DOIUrl":"10.1016/j.jocn.2025.111293","url":null,"abstract":"<div><h3>Objective</h3><div>The present study aimed to assess the impact of two posterior single-door cervical decompression procedures on axial symptoms and cervical sagittal parameters in patients with cervical spondylosis.</div></div><div><h3>Methods</h3><div>A retrospective study was performed on the clinical records of 185 patients diagnosed with cervical spondylosis who had surgical interventions from January 2021 to January 2023. The patients were categorized into two groups: a study group that underwent laminoplasty combined with C3 laminectomy, and a control group that received the standard C3-7 single-door laminoplasty procedure. The groups were compared based on postoperative Japanese Orthopaedic Association (JOA) scores, incidence of axial symptoms, and cervical parameters such as range of motion (ROM), cervical curvature index (CCI), and C2-7 Cobb angle.</div></div><div><h3>Results</h3><div>No notable differences were observed in JOA scores and the rates of neurological function recovery between the groups. The occurrence of axial symptoms was markedly reduced in the study group when compared to the control group, with rates of 22.50 % and 61.54 %, respectively.(<em>P</em> &lt; 0.05). Postoperatively, a significant reduction in CCI was observed in both groups (P &lt; 0.05). However, the study group showed a markedly more substantial improvement in CCI than the control group, with the difference reaching statistical significance (P &lt; 0.05). Additionally, the study group showed significantly less loss of ROM and cervical curvature than the control group post-surgery (P &lt; 0.05).</div></div><div><h3>Conclusion</h3><div>Compared to conventional single door laminoplasty, laminoplasty with C3 laminectomy more effectively decompresses nerves in patients with cervical spondylosis while preserving the structural and functional integrity of the cervical spine and minimizing postoperative axial symptoms. This surgical approach is crucial for maintaining cervical sagittal balance and functional integrity.</div></div>","PeriodicalId":15487,"journal":{"name":"Journal of Clinical Neuroscience","volume":"137 ","pages":"Article 111293"},"PeriodicalIF":1.9,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143923673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}