Meera Alias Devasena Murugesan, Praveena Venkat, Bhavya Basetti
{"title":"Comparison of Ocular Blood Flow in Glaucomatous Eyes and Nonglaucomatous Eyes at a Tertiary Hospital in South India: A Prospective Case-control Study","authors":"Meera Alias Devasena Murugesan, Praveena Venkat, Bhavya Basetti","doi":"10.5005/jp-journals-10078-1428","DOIUrl":"https://doi.org/10.5005/jp-journals-10078-1428","url":null,"abstract":"","PeriodicalId":15419,"journal":{"name":"Journal of Current Glaucoma Practice","volume":"69 26","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141662734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bilateral Chandler Syndrome, Nanophthalmos, and Angle Closure Glaucoma: A Complex Presentation, Challenging Diagnosis, and Pathological Insight—A Case Report","authors":"Ahmed Ameen Ismail, Sarah Abdel-Fattah El-Ruby","doi":"10.5005/jp-journals-10078-1444","DOIUrl":"https://doi.org/10.5005/jp-journals-10078-1444","url":null,"abstract":"","PeriodicalId":15419,"journal":{"name":"Journal of Current Glaucoma Practice","volume":"13 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141661439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. T. Vaz, Afra AL Montenegro, Alexandre DS Quintas Segundo, Gabriela CM Albuquerque, Tarsila VM Alves, Artur L Tenorio, Jerrar Janedson X Silva, Hayana MA Rangel, Rodrigo PC Lira
{"title":"Effect of Sleeping Position on the Retinal Nerve Fiber Layer in Individuals with Glaucoma","authors":"R. T. Vaz, Afra AL Montenegro, Alexandre DS Quintas Segundo, Gabriela CM Albuquerque, Tarsila VM Alves, Artur L Tenorio, Jerrar Janedson X Silva, Hayana MA Rangel, Rodrigo PC Lira","doi":"10.5005/jp-journals-10078-1437","DOIUrl":"https://doi.org/10.5005/jp-journals-10078-1437","url":null,"abstract":"","PeriodicalId":15419,"journal":{"name":"Journal of Current Glaucoma Practice","volume":"29 37","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141659732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brandon L. Vander Zee, Caroline Wilson, John P Berdahl, Daniel C Terveen, Tanner J. Ferguson
{"title":"Superonasal vs Inferonasal Subconjunctival Gel Stent Placement in Patients with Glaucoma","authors":"Brandon L. Vander Zee, Caroline Wilson, John P Berdahl, Daniel C Terveen, Tanner J. Ferguson","doi":"10.5005/jp-journals-10078-1441","DOIUrl":"https://doi.org/10.5005/jp-journals-10078-1441","url":null,"abstract":"","PeriodicalId":15419,"journal":{"name":"Journal of Current Glaucoma Practice","volume":"85 21","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141662601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Neetha Ir Kuzhuppilly, Ravi Chandna, Yogish S Kamath
{"title":"The Efficacy of the Temporal View in Detection of Shallow Anterior Chamber.","authors":"Neetha Ir Kuzhuppilly, Ravi Chandna, Yogish S Kamath","doi":"10.5005/jp-journals-10078-1446","DOIUrl":"10.5005/jp-journals-10078-1446","url":null,"abstract":"<p><strong>Aim and background: </strong>The study aims to determine the accuracy of utilizing a temporal view in the detection of a shallow anterior chamber (AC), in comparison to the conventional anterior view, by evaluation of photographs of the anterior segment of the eye.</p><p><strong>Materials and methods: </strong>Two hundred fifty students who had completed basic undergraduate ophthalmology training as part of their medical education graded the AC depth in anterior segment photographs as \"shallow\" or \"not shallow.\" Each eye was photographed from the anterior and temporal views. A total of 40 photographs of 20 eyes were provided.</p><p><strong>Results: </strong>The ability to detect a shallow AC by temporal view had a sensitivity of 73.3%, compared to 63.2% in the anterior view. The specificity of the temporal view was better at 66.2% compared to the anterior view, which was 65.3%. The overall accuracy of the temporal view in detecting a shallow AC was higher than the anterior view (68.3 vs 64.7%, respectively). Combining both techniques increased the detection of a shallow AC to 88.3%.</p><p><strong>Conclusion: </strong>In our study, the temporal view was more accurate in detecting a shallow AC compared to the anterior view. Integrating the temporal view of AC depth assessment with the traditional anterior view further improves the chances of detecting a shallow AC.</p><p><strong>How to cite this article: </strong>Kuzhuppilly NI, Chandna R, Kamath YS. The Efficacy of the Temporal View in Detection of Shallow Anterior Chamber. J Curr Glaucoma Pract 2024;18(3):98-102.</p>","PeriodicalId":15419,"journal":{"name":"Journal of Current Glaucoma Practice","volume":"18 3","pages":"98-102"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11576346/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142687205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vittorio Pirani, Edoardo Cavallero, Claudia Cesari, Francesco Virgili, Vincenzo Ramovecchi
{"title":"<i>Ab Externo</i> Transconjunctival XEN® 45 Gel Stent Implantation: Efficacy and Safety of a New Surgical Technique.","authors":"Vittorio Pirani, Edoardo Cavallero, Claudia Cesari, Francesco Virgili, Vincenzo Ramovecchi","doi":"10.5005/jp-journals-10078-1443","DOIUrl":"10.5005/jp-journals-10078-1443","url":null,"abstract":"<p><strong>Aim: </strong>To evaluate the efficacy and safety of XEN® 45 gel stent implantation with a new surgical approach by <i>ab externo</i> transconjunctival technique.</p><p><strong>Materials and methods: </strong>A total of 31 eyes of 31 patients affected with primary open-angle glaucoma (POAG) were treated with an <i>ab externo</i> transconjunctival approach. All the XEN gel stent implantations were performed at the Department of Ophthalmology of the Hospital of San Severino Marche, AV3- Asur Marche, Macerata, Italy between January 2021 and May 2021, and the follow-up duration was at least 6 months.</p><p><strong>Results: </strong>A total of 31 eyes of 31 patients (mean age 65.6 ± 12.3 years; 20 males and 11 females) were included in the study. All the patients were affected by POAG. The mean intraocular pressure (IOP) was 25.3 ± 3.8 mm Hg, and the mean number of IOP-lowering topical medications before surgery was 2.7 ± 0.9. No intraoperative complications were reported. During the follow-up, one patient received medical treatment for a choroidal detachment, one patient had a 2 mm hyphema, and one patient had a partial migration of the stent in the anterior chamber. At the 1-month follow-up, the mean IOP was 12.8 ± 2.5 mm Hg and no patient was on IOP-lowering treatment, while at the 3-month and 6-month follow-ups, four patients were on treatment with one IOP-lowering drug. During the follow-up period, seven patients required postsurgical bleb needling, and one patient underwent a revision with PreserFlo® Microshunt implantation. The final mean IOP was 15.9 ± 2.7 mm Hg, and 27 out of 31 patients had an IOP of <18 mm Hg.</p><p><strong>Conclusion: </strong><i>Ab externo</i> transconjunctival XEN® 45 gel stent implantation represents a safe and effective surgical treatment approach.</p><p><strong>Clinical significance: </strong>The <i>ab externo</i> approach represents a safe and effective technique, allowing early surgical timing and widening the group of patients who could benefit from the filtrating surgical technique before many years of topical medical treatment, which causes marked conjunctival alteration.</p><p><strong>How to cite this article: </strong>Pirani V, Cavallero E, Cesari C, <i>et al.</i> <i>Ab Externo</i> Transconjunctival XEN® 45 Gel Stent Implantation: Efficacy and Safety of a New Surgical Technique. J Curr Glaucoma Pract 2024;18(3):94-97.</p>","PeriodicalId":15419,"journal":{"name":"Journal of Current Glaucoma Practice","volume":"18 3","pages":"94-97"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11576342/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142687146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
James Richardson-May, Sameh A Ibrahim, Kitty Law, Abeir Baltmr, Ahmed Elbably
{"title":"Canaloplasty and Trabeculotomy Using the OMNI Surgical System in Three Patients with Angle Closure: A Case Series.","authors":"James Richardson-May, Sameh A Ibrahim, Kitty Law, Abeir Baltmr, Ahmed Elbably","doi":"10.5005/jp-journals-10078-1449","DOIUrl":"10.5005/jp-journals-10078-1449","url":null,"abstract":"<p><strong>Aim and background: </strong>The OMNI surgical system allows for 360° canaloplasty and trabeculotomy for patients with glaucoma, either as a standalone procedure or in combination with cataract surgery. There is currently limited evidence on its use in forms of angle-closure glaucoma, though other microinvasive glaucoma surgeries have been used. We present three patients with angle closure who underwent the procedure.</p><p><strong>Methods: </strong>Retrospective review of three patients who underwent canaloplasty and trabeculotomy with the OMNI surgical system with forms of angle closure. Data on demographics, intraocular pressure (IOP), glaucoma medication use, best corrected visual acuity (BCVA), visual fields (VFs), and complications were collected for a 6-month period.</p><p><strong>Results: </strong>Three eyes of three patients underwent the procedure: one with primary angle closure glaucoma (PACG), one acute angle closure, and one primary angle closure (PAC). All had surgery combined with phacoemulsification and intraocular lens (IOL) implantation. The mean age was 56 years. Preoperative IOP was 25.33 ± 2.49 mm Hg, improving to 11.67 ± 2.87 mm Hg at 6 months. Mean glaucoma medication use was reduced by 3.00, from 3.67 ± 1.21 to 0.67 ± 0.94. Preoperative mean BCVA was 0.10 ± 0.08 and 0.20 ± 0.08 LogMAR at 6 months. Mean deviation (MD) on VFs was -9.67 preoperatively and -6.72 at 6 months. Two patients had mild, self-limiting hyphema postoperatively which resolved without further intervention; no other complications were reported.</p><p><strong>Conclusion: </strong>We have found the OMNI surgical system to be a safe, effective tool in the management of angle-closure glaucomas in a small cohort of patients.</p><p><strong>Clinical significance: </strong>The OMNI surgical system has the potential to add a less invasive surgical solution in the management of angle closure glaucoma, prior to the use of filtering surgery such as trabeculectomy or glaucoma drainage device. Larger trials assessing the use of microinvasive glaucoma surgery (MIGS) in these patients will be eagerly received.</p><p><strong>How to cite this article: </strong>Richardson-May J, Ibrahim SA, Law K, <i>et al.</i> Canaloplasty and Trabeculotomy Using the OMNI Surgical System in Three Patients with Angle Closure: A Case Series. J Curr Glaucoma Pract 2024;18(3):117-120.</p>","PeriodicalId":15419,"journal":{"name":"Journal of Current Glaucoma Practice","volume":"18 3","pages":"117-120"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11576345/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142687201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Julia Nguyen, Orlando G González-Martínez, Albert S Khouri
{"title":"MicroPulse Transscleral Laser Therapy: A Retrospective Study of Dose Efficacy and Safety.","authors":"Julia Nguyen, Orlando G González-Martínez, Albert S Khouri","doi":"10.5005/jp-journals-10078-1450","DOIUrl":"10.5005/jp-journals-10078-1450","url":null,"abstract":"<p><strong>Aim: </strong>To evaluate the efficacy and safety of MicroPulse transscleral laser therapy (MPTLT) for cyclophotocoagulation in the treatment of glaucoma with different doses of energy.</p><p><strong>Materials and methods: </strong>A retrospective review was done of 136 eyes in 90 patients treated with MPTLT between 2018 and 2022. Intraocular pressures (IOP) at follow-ups were compared with a paired student <i>t</i>-test and treatment outcomes with a Chi-squared test. The cohort was stratified into subgroups to analyze the effect of total applied energy on outcomes. The variance between energy groups was analyzed with the Kruskal-Wallis test adjusted for multiple comparisons.</p><p><strong>Results: </strong>A total of 136 eyes of 90 patients underwent MPTLT for mostly open angle (36.0%) and childhood glaucoma (30.1%). Applied energy range was between 37.5 and 195.6 J with a mean [standard deviation (SD)] of 100.7 (34.3) J. Applied energy of 125-200 J reduced IOP the most at 2 years with 90% of eyes within 6-21 mm Hg and 66% of eyes having IOP reduced at least 20% (<i>p</i> < 0.001) from baseline. However, at 2 years, energy 50-75 J achieved fewer eyes with two or more Snellen lines lost than energy 125-200 J and a lower proportion of eyes with at least one symptom (<i>p</i> < 0.05). No severe complications of hypotony, phthisis bulbi, or chronic inflammation were reported.</p><p><strong>Conclusion: </strong>IOP reduction and safety outcome of MPTLT varied with applied energy. Doses should be adjusted to target the treatment goals for individual patients.</p><p><strong>Clinical significance: </strong>MPTLT was found to be effective in lowering IOP in glaucoma. Using high levels of energy is associated with higher rates of complications.</p><p><strong>How to cite this article: </strong>Nguyen J, González-Martínez OG, Khouri AS. MicroPulse Transscleral Laser Therapy: A Retrospective Study of Dose Efficacy and Safety. J Curr Glaucoma Pract 2024;18(3):121-129.</p>","PeriodicalId":15419,"journal":{"name":"Journal of Current Glaucoma Practice","volume":"18 3","pages":"121-129"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11576340/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142687203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Samuel A Cohen, Ann C Fisher, Benjamin Y Xu, Brian J Song
{"title":"Comparing the Accuracy and Readability of Glaucoma-related Question Responses and Educational Materials by Google and ChatGPT.","authors":"Samuel A Cohen, Ann C Fisher, Benjamin Y Xu, Brian J Song","doi":"10.5005/jp-journals-10078-1448","DOIUrl":"10.5005/jp-journals-10078-1448","url":null,"abstract":"<p><strong>Aim and background: </strong>Patients are increasingly turning to the internet to learn more about their ocular disease. In this study, we sought (1) to compare the accuracy and readability of Google and ChatGPT responses to patients' glaucoma-related frequently asked questions (FAQs) and (2) to evaluate ChatGPT's capacity to improve glaucoma patient education materials by accurately reducing the grade level at which they are written.</p><p><strong>Materials and methods: </strong>We executed a Google search to identify the three most common FAQs related to 10 search terms associated with glaucoma diagnosis and treatment. Each of the 30 FAQs was inputted into both Google and ChatGPT and responses were recorded. The accuracy of responses was evaluated by three glaucoma specialists while readability was assessed using five validated readability indices. Subsequently, ChatGPT was instructed to generate patient education materials at specific reading levels to explain seven glaucoma procedures. The accuracy and readability of procedural explanations were measured.</p><p><strong>Results: </strong>ChatGPT responses to glaucoma FAQs were significantly more accurate than Google responses (97 vs 77% accuracy, respectively, <i>p</i> < 0.001). ChatGPT responses were also written at a significantly higher reading level (grade 14.3 vs 9.4, respectively, <i>p</i> < 0.001). When instructed to revise glaucoma procedural explanations to improve understandability, ChatGPT reduced the average reading level of educational materials from grade 16.6 (college level) to grade 9.4 (high school level) (<i>p</i> < 0.001) without reducing the accuracy of procedural explanations.</p><p><strong>Conclusion: </strong>ChatGPT is more accurate than Google search when responding to glaucoma patient FAQs. ChatGPT successfully reduced the reading level of glaucoma procedural explanations without sacrificing accuracy, with implications for the future of customized patient education for patients with varying health literacy.</p><p><strong>Clinical significance: </strong>Our study demonstrates the utility of ChatGPT for patients seeking information about glaucoma and for physicians when creating unique patient education materials at reading levels that optimize understanding by patients. An enhanced patient understanding of glaucoma may lead to informed decision-making and improve treatment compliance.</p><p><strong>How to cite this article: </strong>Cohen SA, Fisher AC, Xu BY, <i>et al.</i> Comparing the Accuracy and Readability of Glaucoma-related Question Responses and Educational Materials by Google and ChatGPT. J Curr Glaucoma Pract 2024;18(3):110-116.</p>","PeriodicalId":15419,"journal":{"name":"Journal of Current Glaucoma Practice","volume":"18 3","pages":"110-116"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11576343/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142687202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brandon Huynh, Colin Clement, Vuong Nguyen, Stephen O'Hagan, Frank Howes, Peter Macken, David Manning, Ridia Lim, Jed Lusthaus, Mitchell Lawlor
{"title":"12-month Safety and Efficacy Outcomes of a Standalone Trabecular Bypass Device.","authors":"Brandon Huynh, Colin Clement, Vuong Nguyen, Stephen O'Hagan, Frank Howes, Peter Macken, David Manning, Ridia Lim, Jed Lusthaus, Mitchell Lawlor","doi":"10.5005/jp-journals-10078-1447","DOIUrl":"10.5005/jp-journals-10078-1447","url":null,"abstract":"<p><strong>Purpose: </strong>To analyze the outcomes of the iStent inject in a real-world clinical setting as a standalone procedure to lower intraocular pressure (IOP) in open-angle glaucoma.</p><p><strong>Materials and methods: </strong>Patients with open-angle glaucoma having undergone iStent inject insertion without concurrent cataract extraction were included in this multicenter observational real-world study in Australia. Patient data was entered into the Fight Glaucoma Blindness! Registry. Assessments through 12 months included glaucoma subtype, IOP, medications, best-corrected visual acuity (BCVA), secondary surgical procedures, and adverse events. Kaplan-Meier survival curves for outcomes were reported according to the World Glaucoma Association (WGA).</p><p><strong>Results: </strong>Sixty-one eyes from 44 patients with a mean age of 76 ± 11.4 underwent standalone iStent inject implantation. The mean ± SD preoperative IOP was 17.5 ± 7.5 mm Hg, and the mean preoperative number of topical medications was 2.5 ± 1.5. At 12 months postoperatively, there was no statistically significant IOP reduction, while the number of glaucoma medications used was reduced to 1.4 ± 1.5 (<i>p</i> < 0.001). Fourteen point one percent of eyes required a secondary pressure-lowering procedure within the 12-month follow-up window.</p><p><strong>Conclusion: </strong>This assessment of standalone iStent inject implantation did not show any significant reduction in IOP, but there was a significant decrease in medication use in the real-world clinical setting. The procedure is safe with minimal adverse outcomes; however, a subset of patients required secondary procedures within 12 months of follow-up.</p><p><strong>How to cite this article: </strong>Huynh B, Clement C, Nguyen V, <i>et al.</i> 12-month Safety and Efficacy Outcomes of a Standalone Trabecular Bypass Device. J Curr Glaucoma Pract 2024;18(3):103-109.</p>","PeriodicalId":15419,"journal":{"name":"Journal of Current Glaucoma Practice","volume":"18 3","pages":"103-109"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11576339/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142687084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}