Journal of Current Glaucoma Practice最新文献

{"title":"Viscodilation of Schlemm's Canal Combined with Goniectomy Using a 30 G Needle (Visco-Bent Ab Interno Needle Goniectomy).","authors":"Tanuj Dada, Nitika Beri, Anin Sethi, Namrata Sharma","doi":"10.5005/jp-journals-10078-1424","DOIUrl":"10.5005/jp-journals-10078-1424","url":null,"abstract":"<p><strong>Background and aim: </strong>Bent ab interno needle goniectomy (BANG) is a low-cost minimally invasive glaucoma surgery (MIGS) technique that has gained wide popularity in developing nations. However, the risk of injury to surrounding angle structures and especially the outer wall of Schlemm's canal (SC) is the main drawback of this technique. We describe a simple and easy-to-perform modification, \"Visco-BANG,\" to improve the safety and efficacy of the BANG procedure.</p><p><strong>Technique: </strong>A 30 gauge (G) needle attached to a syringe filled with cohesive viscoelastic is used. The needle is bent at the proximal junction of the bevel with bevel towards the operating surgeon. The needle is then inserted into the SC and viscoelastic injected to dilate the canal, creating a buffer between the inner and outer walls of SC, which is followed by cutting of a trabecular meshwork (TM) strip.</p><p><strong>Conclusion: </strong>The current modification can prevent damage to adjoining angle structures, including the outer wall of SC, which is critical for aqueous outflow. It can potentially increase efficacy of the BANG procedure by incorporating viscodilation of the SC along with removal of the TM.</p><p><strong>Clinical significance: </strong>Injury to surrounding structures causes a fibrotic response, which is the main cause of failure for the BANG procedure. Prevention of injury to adjoining structures and dilatation of the SC can potentially increase the long-term success rates of this procedure.</p><p><strong>How to cite this article: </strong>Dada T, Beri N, Sethi A, <i>et al.</i> Viscodilation of Schlemm's Canal Combined with Goniectomy Using a 30 G Needle (Visco-Bent Ab Interno Needle Goniectomy). J Curr Glaucoma Pract 2023;17(4):210-213.</p>","PeriodicalId":15419,"journal":{"name":"Journal of Current Glaucoma Practice","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10803280/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139544651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ocular Surface Evaluation after Switch from Latanoprost 0.005% to Latanoprostene Bunod 0.024.","authors":"Virginia Zanutigh, Leila Galetto, Florencia Valvecchia, Celina Logioco","doi":"10.5005/jp-journals-10078-1422","DOIUrl":"10.5005/jp-journals-10078-1422","url":null,"abstract":"<p><strong>Aim and background: </strong>To evaluate the ocular surface of patients treated with latanoprost (LT) 0.005% who switched to latanoprostene bunod (LBN) 0.024%.</p><p><strong>Materials and methods: </strong>A prospective and nonrandomized clinical study of a case series was performed, including patients with chronic open-angle glaucoma who were on previous LT-only treatment and, after a washout period, switched to LBN, with a 3-month follow-up. The main parameter to be evaluated was the ocular surface disease index (OSDI) test. In addition, best-corrected visual acuity (BCVA), intraocular pressure (IOP), biomicroscopic aspect of the ocular surface, measuring tear breakup time, fluorescein staining (grading performed on Oxford scale) and Schirmer I test were evaluated.</p><p><strong>Results: </strong>A total of 36 patients (72 eyes) were included, 21 women (58.3%) and 15 men (41.7%, with a mean age of 65.6 ± 10.9 years (37-86). The initial OSDI score was 17.8 ± 12.1 and improved to 11.1 ± 10.5 (<i>p</i> < 0.01). From the data evaluated at biomicroscopy, an improvement was observed in the Oxford scale from 0.6 ± 0.7 to 0.2 ± 0.8 (<i>p</i>: 0.01), but no statistically significant changes were observed in the break-up time (BUT) and Schirmer. BCVA remained stable, as did IOP, which was initially 13.4 ± 2.1 mm Hg and, after performing the LBN treatment change, went to 13.1 ± 1.7 mm Hg.</p><p><strong>Conclusion: </strong>After the change of treatment from LT 0.005% to LBN 0.024%, the patients had an improvement in the ocular surface, maintaining control of their IOP. The need to investigate possible beneficial mechanisms on the ocular surface in glaucoma patients treated with LBN, potentially related to nitric oxide, is raised.</p><p><strong>Clinical significance: </strong>Patients treated with LT 0.005% who switched to LBN 0.024% had an improvement in ocular surface symptoms and signs, keeping IOP under control.Latanoprostene bunod (LBN) 0.024% may have beneficial effects on the ocular surface, which should be further studied.</p><p><strong>How to cite this article: </strong>Zanutigh V, Galetto L, Valvecchia F, <i>et al.</i> Ocular Surface Evaluation after Switch from Latanoprost 0.005% to Latanoprostene Bunod 0.024%. J Curr Glaucoma Pract 2023;17(4):205-209.</p>","PeriodicalId":15419,"journal":{"name":"Journal of Current Glaucoma Practice","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10803279/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139546622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Success of Endoscopic Laser Cyclophotocoagulation vs Repeat Transscleral Treatment after Prior Transscleral Cycloablation.","authors":"Christiane Al-Haddad, Anita Barikian, Zeinab El Moussawi, Nour A Nasser, Bahaa' Noureddine, Ziad Bashshur","doi":"10.5005/jp-journals-10078-1426","DOIUrl":"10.5005/jp-journals-10078-1426","url":null,"abstract":"<p><strong>Aim: </strong>To compare the efficacy of endoscopic cyclophotocoagulation (ECP) vs repeat transscleral cyclophotocoagulation (TCP) in eyes with persistent glaucoma despite prior treatment with TCP.</p><p><strong>Materials and methods: </strong>This was a retrospective chart review of glaucoma patients at the American University of Beirut Medical Center over 10 years who underwent ECP or repeat TCP. We reported qualified and complete success; success was defined as postoperative intraocular pressure (IOP) ≤21 mm Hg, with (qualified) or without medications (complete) and without procedure-related complications.</p><p><strong>Results: </strong>This study included 23 eyes of 21 patients with various forms of uncontrolled glaucoma who had failed TCP. A total of 13 eyes of 12 patients underwent ECP with a mean age of 39.9 ± 23.2 years, and 10 eyes of nine patients underwent repeat TCP with a mean age of 27.2 ± 22.6 years. A significant decrease in IOP was observed from 38.5 ± 7.9 mm Hg preoperatively to 25.2 ± 8.8 mm Hg postrepeat TCP (<i>p</i> = 0.006) and from 33.0 ± 9.5 to 12.8 ± 3.9 mm Hg post-ECP (<i>p</i> < 0.001), noted at a mean follow-up time of 39.2 ± 44.4 and 41.5 ± 37.4 months, respectively. The mean number of antiglaucoma medications decreased in the two groups (from 3.8 ± 1.0 preoperatively to 1.8 ± 0.9 postoperatively for ECP and from 3.5 ± 1.3 to 3.1 ± 0.9 postoperatively for TCP); however, the drop was only statistically significant post-ECP. Qualified success was significantly higher after ECP vs repeat TCP (91.7 vs 40%, respectively). Complete success was achieved only in 1/12 (8.3%) eyes in the ECP group.</p><p><strong>Conclusion: </strong>Endoscopic cyclophotocoagulation (ECP) performed in glaucomatous eyes previously treated with transscleral cycloablation provided more IOP control as compared to repeat TCP by directly treating viable tissue in previously skipped ciliary processes and in between processes.</p><p><strong>Clinical significance: </strong>In glaucomatous eyes previously treated with transscleral cycloablation, ECP attained better IOP control than repeat transscleral cycloablation.</p><p><strong>How to cite this article: </strong>Al-Haddad C, Barikian A, Moussawi ZE, <i>et al.</i> Success of Endoscopic Laser Cyclophotocoagulation vs Repeat Transscleral Treatment after Prior Transscleral Cycloablation. J Curr Glaucoma Pract 2023;17(4):191-196.</p>","PeriodicalId":15419,"journal":{"name":"Journal of Current Glaucoma Practice","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10803276/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139544610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postoperative Management of Kahook Dual Blade Goniotomy with Phacoemulsification Cataract Extraction.","authors":"Faith Birnbaum, Susan Wakil, Daniel M Vu, Shan McBurney-Lin, Mohammed ElMallah, Henry Tseng","doi":"10.5005/jp-journals-10078-1419","DOIUrl":"10.5005/jp-journals-10078-1419","url":null,"abstract":"<p><strong>Aim: </strong>To review the efficacy and safety of two common postoperative regimens following Kahook Dual Blade goniotomy with phacoemulsification cataract extraction (KDB-CE).</p><p><strong>Materials and methods: </strong>This is a retrospective review of eyes undergoing KDB-CE from May 2016 to 2018 by a single surgeon. Almost 12-month follow-up data were assessed for two common postop regimens-treatment with (1) topical prednisolone acetate 1% with pilocarpine 1% (pred-pilo) or (2) difluprednate 0.05% postoperatively. Postoperative results were compared to each respective baseline intraocular pressure (IOP) levels.</p><p><strong>Results: </strong>There were 53 eyes in the difluprednate group and 25 eyes in the pred-pilo group. In the difluprednate group, the IOP decreased at postoperative day 1 (POD1) [16 ± 5 baseline vs 15 ± 5 POD1, mean ± standard deviation (SD) in mm Hg, and <i>p</i> = 0.321], but increased at postoperative week 1 (POW1) due to a 15% rate of IOP-spikes (19 ± 9, <i>p</i> = 0.099). The number of IOP-lowering drops decreased from baseline (2 ± 1 drops) to 1 ± 1 drops at POD1 (<i>p</i> < 0.0001), and remained at 1 ± 1 drops through postoperative month 12 (POM12) (<i>p</i> < 0.0001). In the pred-pilo group, there was a statistically significant decrease in mean IOP at POW1 (16 ± 4 POW1 vs 18 ± 6 baseline, <i>p</i> = 0.044), which persisted through POM6. The number of IOP-lowering drops was not statistically significantly lower from baseline at POM3 (2 ± 1 at POM3, <i>p</i> = 0.188). Spikes in IOP, corneal edema, and hyphema were the most common complications.</p><p><strong>Conclusion: </strong>Both postoperative regimens were effective following KDB-CE at reducing IOP at 12 months. The difluprednate group was likely to experience an IOP-spike at POW1 but used fewer IOP-lowering drops 12 months after KDB goniotomy. In the pred-pilo group, the number of IOP-lowering drops was equivalent to baseline levels at POM3. Aside from IOP spikes, there were similar complication rates observed between the two postoperative regimens. Due to demographic differences, it was not possible to compare relative IOP-lowering efficacy between the two postoperative regimens.</p><p><strong>Clinical significance: </strong>It is efficacious and safe to use either postoperative regimen following KBD-CE. Postoperative trajectories may differ with respect to the postoperative regimen, but further randomized controlled trials are needed to compare various topical steroid medications for postoperative regimens following KDB-CE.</p><p><strong>How to cite this article: </strong>Birnbaum F, Wakil S, Vu DM, <i>et al.</i> Postoperative Management of Kahook Dual Blade Goniotomy with Phacoemulsification Cataract Extraction. J Curr Glaucoma Pract 2023;17(4):169-174.</p>","PeriodicalId":15419,"journal":{"name":"Journal of Current Glaucoma Practice","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10803275/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139546632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Retrospective Cohort Study on the Difficulties of Diagnosing and Managing Glaucoma in Patients with Coexistent Neurodegenerative Disease.","authors":"Elizabeth C Ciociola, Kush Patel, Tyler Blahnik, Arko Ghosh, Meredith R Klifto, David Fleischman","doi":"10.5005/jp-journals-10078-1415","DOIUrl":"10.5005/jp-journals-10078-1415","url":null,"abstract":"<p><strong>Aim: </strong>To investigate the limitations of diagnosing glaucoma in patients with coexistent neurodegenerative disease (NDD) by collecting information on demographics, examination findings, optical coherence tomography (OCT), and visual field (VF) tests.</p><p><strong>Materials and methods: </strong>Retrospective cohort study of patients with primary open-angle glaucoma and coexistent dementia, multiple sclerosis (MS), Parkinson's disease (PD), or cerebrovascular accident (CVA) from 2014 to 2020. We included patients with a minimum of 3 years of follow-up. Demographics, ophthalmic exam, OCT, and VF findings were reported and compared across NDD groups using the Chi-squared and analysis of variance tests.</p><p><strong>Results: </strong>We included 199 patients with glaucoma and coexistent NDD, including dementia (51.3%), CVA (11.2%), PD (18.1%), and MS (19.6%). Cupping, neuroretinal rim thinning, pallor, and peripapillary atrophy of the optic nerve were most frequently observed. There was a high number of missing values from OCT to VF tests, and zero patients had a complete OCT or VF test. Additionally, 67.8 and 77.4% of patients received <1 OCT and VF/year, respectively. Retinal nerve fiber layer (RNFL) thinning was observed most frequently in the superior (33.2% OD and 30.7% OS) and inferior (25.6% OD and 30.2% OS) quadrants, with the most significant thinning seen in CVA patients compared to other NDDs (<i>p</i> < 0.05). Glaucoma hemifield tests (GHTs) were abnormal in 23.1% OD and 22.6% OS, and the average mean deviation was -7.43 [standard deviation (SD) 8.23] OD and -8.79 (SD 7.99) OS.</p><p><strong>Conclusion: </strong>The OCT and VF tests are frequently unavailable and may be confounded in patients with coexistent glaucoma and NDDs, complicating glaucoma diagnosis and management.</p><p><strong>Clinical significance: </strong>Diagnosing and managing glaucoma in patients with coexistent NDD is difficult, given the lack of available and reliable OCT and VF testing data. Providers may be forced to rely on intraocular pressure (IOP) and other imperfect measures.</p><p><strong>How to cite this article: </strong>Ciociola EC, Patel K, Blahnik T, <i>et al.</i> A Retrospective Cohort Study on the Difficulties of Diagnosing and Managing Glaucoma in Patients with Coexistent Neurodegenerative Disease. J Curr Glaucoma Pract 2023;17(3):126-133.</p>","PeriodicalId":15419,"journal":{"name":"Journal of Current Glaucoma Practice","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618602/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71424038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Proteomic Analysis of the Aqueous Humor from Patients with Pseudoexfoliation Syndrome.","authors":"Muge Toprak, Nursen Yuksel, Gurler Akpinar, Murat Kasap, Dilara Pirhan, Busra Yilmaz Tugan","doi":"10.5005/jp-journals-10078-1411","DOIUrl":"10.5005/jp-journals-10078-1411","url":null,"abstract":"<p><strong>Purpose: </strong>The goal of this study was to pinpoint potential molecular pathways that may have contributed to the onset of pseudoexfoliation syndrome (PEX), a systemic illness associated with aging that has no known cause and is brought on by the deposition of fibrillary white flaky debris in ocular tissues.</p><p><strong>Materials and methods: </strong>Protein pools representing each group were created using two-dimensional gel electrophoresis (2DE) in conjunction with a matrix-assisted laser desorption ionization-time of flight/time of flight (MALDI-TOF/TOF) mass spectrometer. Aqueous humor (AH) from patients with PEX and cataracts was also collected for a comprehensive study of the data; ingenuity pathway analysis (IPA) was used for the discovered proteins.</p><p><strong>Results: </strong>In comparison to controls, 2DE showed that 10 sites in PEX patients had differently altered gene expression. Two of these proteins, transthyretin (TTR) and apolipoprotein A4 (ApoA4) were significantly overexpressed in PEX patients, but the remaining proteins were only mildly altered. The liver X receptor (LXR) and the retinoid X receptors (RXR) may play a crucial role in the pathophysiology of PEX according to IPA employing these 10 proteins.</p><p><strong>Conclusion: </strong>The altered proteins, particularly ApoA4 and TTR, may be important in revealing the molecular process behind PEX, as anticipated by IPA.</p><p><strong>How to cite this article: </strong>Toprak M, Yuksel N, Akpinar G, <i>et al.</i> Comparative Proteomic Analysis of the Aqueous Humor from Patients with Pseudoexfoliation Syndrome. J Curr Glaucoma Pract 2023;17(3):118-125.</p>","PeriodicalId":15419,"journal":{"name":"Journal of Current Glaucoma Practice","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618601/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71424040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effectiveness of a Nurse-led Glaucoma Education on Patient Knowledge and Compliance Motivation Levels: A 1-year Prospective Case Series.","authors":"James J Sng,&nbsp;Bryan C H Ang,&nbsp;Wai Cheng Soo Hoo,&nbsp;Angela P H Lim,&nbsp;Hwei Yee Teo,&nbsp;Leonard W L Yip","doi":"10.5005/jp-journals-10078-1418","DOIUrl":"10.5005/jp-journals-10078-1418","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the impact of a nurse-led glaucoma education program on patient knowledge and compliance levels in an Asian population.</p><p><strong>Materials and methods: </strong>A 1-year prospective case series involving 69 adult glaucoma patients. Each patient attended a standardized nurse-led glaucoma education session. A questionnaire was administered by a single nurse-clinician and analyzed at three time points (preeducation for baseline, immediately posteducation, and at the 1-year follow-up) to evaluate for associations with patient knowledge and compliance motivation levels.</p><p><strong>Results: </strong>A total of 64 patients were included in the final analysis. Patients with higher educational qualifications or who were employed had better baseline knowledge of glaucoma. Younger patients had higher baseline compliance motivation levels. Immediately posteducation, both median patient knowledge score and compliance motivation levels had a statistically significant increase. Patients on more glaucoma eye drops had greater immediate improvement in confidence in eye drop application. Patients with more positive Humphrey visual field mean deviation values had a greater immediate improvement in confidence in their understanding of glaucoma. A total of 34 patients were readministered the questionnaire at the 1-year time point. Median score for patient knowledge was highest at this point. Employed patients demonstrated better patient knowledge at baseline and at 1-year time point compared to unemployed patients. Unemployed patients experienced a significant improvement in scores from baseline to immediately posteducation, but improvement from immediately posteducation to the 1-year time point was insignificant was insignificant.</p><p><strong>Conclusion: </strong>Our study has examined the effectiveness of a nurse-led glaucoma education program in an Asian population, demonstrating improvement in both patient knowledge and compliance motivation levels up to 1 year after intervention.</p><p><strong>How to cite this article: </strong>Sng JJ, Ang BCH, Soo Hoo WC, <i>et al</i>. The Effectiveness of a Nurse-led Glaucoma Education on Patient Knowledge and Compliance Motivation Levels: A 1-year Prospective Case Series. J Curr Glaucoma Pract 2023;17(3):149-156.</p>","PeriodicalId":15419,"journal":{"name":"Journal of Current Glaucoma Practice","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618600/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71424045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Decision Factors for Glaucoma Suspects and Ocular Hypertensive Treatment at an Academic Center.","authors":"Elizabeth C Ciociola, Alicia Anderson, Huijun Jiang, Ian Funk, Feng-Chang Lin, Jean-Claude Mwanza, Meredith R Klifto, David Fleischman","doi":"10.5005/jp-journals-10078-1417","DOIUrl":"10.5005/jp-journals-10078-1417","url":null,"abstract":"<p><strong>Aims and background: </strong>Practice guidelines assert that high-risk glaucoma suspects should be treated. Yet, there is ambiguity regarding what constitutes a high enough risk for treatment. The purpose of this study was to determine which factors contribute to the decision to treat glaucoma suspects and ocular hypertensive patients in an academic ophthalmology practice.</p><p><strong>Materials and methods: </strong>Retrospective cohort study of glaucoma suspects or ocular hypertensives at an academic ophthalmology practice from 2014 to 2020. Demographics, comorbidities, intraocular pressure (IOP), optical coherence tomography (OCT) findings, and visual field measurements were compared between treated and untreated patients. A multivariable logistic regression model assessed predictors of glaucoma suspected treatment.</p><p><strong>Results: </strong>Of the 388 patients included, 311 (80%) were untreated, and 77 (20%) were treated. There was no statistical difference in age, race/ethnicity, family history of glaucoma, central corneal thickness (CCT), or any visual field parameters between the two groups. Treated glaucoma suspects had higher IOP, thinner retinal nerve fiber layers (RNFL), more RNFL asymmetry, thinner ganglion cell-inner plexiform layers (GCIPL), and a higher prevalence of optic disc drusen, disc hemorrhage, ocular trauma, and proliferative diabetic retinopathy (PDR) (<i>p</i> < 0.05 for all). In the multivariable model, elevated IOP {odds ratio [OR] 1.16 [95% confidence interval (CI) 1.04-1.30], <i>p</i> = 0.008}, yellow temporal [5.76 (1.80-18.40), <i>p</i> = 0.003] and superior [3.18 (1.01-10.0), <i>p</i> = 0.05] RNFL quadrants, and a history of optic disc drusen [8.77 (1.96-39.34), <i>p</i> = 0.005] were significant predictors of glaucoma suspect treatment.</p><p><strong>Conclusion: </strong>Higher IOP, RNFL thinning, and optic disc drusen were the strongest factors in the decision to treat a glaucoma suspect or ocular hypertensive patient. RNFL asymmetry, GCIPL thinning, and ocular comorbidities may also factor into treatment decisions.</p><p><strong>Clinical significance: </strong>Understanding the clinical characteristics that prompt glaucoma suspect treatment helps further define glaucoma suspect disease status and inform when treatment should be initiated.</p><p><strong>How to cite this article: </strong>Ciociola EC, Anderson A, Jiang H, <i>et al.</i> Decision Factors for Glaucoma Suspects and Ocular Hypertensive Treatment at an Academic Center. J Curr Glaucoma Pract 2023;17(3):157-165.</p>","PeriodicalId":15419,"journal":{"name":"Journal of Current Glaucoma Practice","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618603/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71424041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lifestyle Measures for Glaucoma Patients: An Objective Social Media Content Analysis.","authors":"Rutvi Chahal,&nbsp;Ankush Jindal,&nbsp;Uday Pratap Singh Parmar,&nbsp;Rohan Bir Singh,&nbsp;Shibal Bhartiya,&nbsp;Parul Ichhpujani","doi":"10.5005/jp-journals-10078-1412","DOIUrl":"10.5005/jp-journals-10078-1412","url":null,"abstract":"<p><strong>Aim: </strong>In this study, we analyze the content quality and characteristics of the most viewed search results on various internet platforms related to lifestyle measures for patients with glaucoma.</p><p><strong>Materials and methods: </strong>In this internet-based cross-sectional study, we used search keywords \"glaucoma,\" \"lifestyle,\" \"glaucoma,\" and \"exercise\" on the most popular internet platforms-Google, Facebook, YouTube, and Reddit. The top 30 Google searches about each of the keyword combinations were identified. We also assessed the first 30 videos on YouTube and Facebook Watch, the first 30 Reddit posts and the first 30 Google images about each of the keyword combinations. The quality of content from the platforms was evaluated by three independent reviewers using the well-established Sandvik score, Health on Net (HON) code, and risk score for different uploaders. The quality of content regarding lifestyle measures in glaucoma uploaded by healthcare professionals (HCPs) was further evaluated.</p><p><strong>Results: </strong>The established criteria resulted in 48 websites from the Google search engine, 22 videos from YouTube, 37 posts from Reddit, and 28 videos from Facebook Watch, which were included in the final analysis. The mean Sandvik scores were 11.14 ± 1.8 (Google webpages), 10.4 ± 2.19 (YouTube videos), 10.54 ± 2.21 (Facebook Watch), and 4.24 ± 1.18 (Reddit). The mean risk scores were 0.22 ± 0.68 (YouTube videos), 0.18 ± 0.47 (Facebook Watch), and 0.11 ± 0.31 (Reddit). The mean HON code scores were 5.45 ± 1.62 (YouTube), 6.55 ± 1.44 (Google webpages), 5.29 ± 1.04 (Facebook Watch), and 8.27 ± 3.05 (Reddit). The content uploaded by HCPs was primarily from ophthalmologists and had significantly (<i>p</i> < 0.05) higher content quality scores. The majority of the content recommended aerobic exercise as a lifestyle measure in patients with glaucoma as an adjuvant to medical and surgical management.</p><p><strong>Conclusion: </strong>The majority of the content regarding lifestyle measures in glaucoma was uploaded by HCPs and had medically accurate and well-referenced information, especially on Google and YouTube.</p><p><strong>Clinical significance: </strong>Primary care physicians and ophthalmologists can reliably use social media content to guide recently diagnosed patients about the requisite lifestyle measures.</p><p><strong>How to cite this article: </strong>Chahal R, Jindal A, Parmar UPS, <i>et al.</i> Lifestyle Measures for Glaucoma Patients: An Objective Social Media Content Analysis. J Curr Glaucoma Pract 2023;17(3):141-148.</p>","PeriodicalId":15419,"journal":{"name":"Journal of Current Glaucoma Practice","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618604/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71424042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Profile of Primary Open-angle Glaucoma Patients at an Eye Center in Nigeria.","authors":"Ngozika E Ezinne,&nbsp;Michael A Kwarteng,&nbsp;Kingsley K Ekemiri,&nbsp;Victoria I Iroanachi,&nbsp;Selassie Tagoh,&nbsp;Grace Ogbonna,&nbsp;Khathutshelo P Mashige","doi":"10.5005/jp-journals-10078-1413","DOIUrl":"10.5005/jp-journals-10078-1413","url":null,"abstract":"<p><strong>Aim: </strong>Globally, one of the leading causes of preventable blindness is primary open-angle glaucoma (POAG). The study assessed the clinical presentations of POAG patients attending an eye center in Abuja, Nigeria.</p><p><strong>Materials and methods: </strong>Records of 188 eyes, collected from 94 patients diagnosed with POAG for a period of 1 year at the eye center, were reviewed. Clinical records, including age, gender, visual acuity (VA), central cornea thickness (CCT), intraocular pressure (IOP), cup-to-disk ratios, and retinal nerve fiber layer (RNFL) thickness of the participants, were extracted and analyzed.</p><p><strong>Results: </strong>The majority of the participants were males (56.4%) and adults (57.4%), most of whom had normal VA (>70% in each eye). Our analysis revealed normal average estimates of RNFL thickness, IOP, and CCT among the participants. Females had thicker RNFL compared to males (<i>p</i> = 0.02). Although CCT decreased with age (<i>r</i> = -0.28, <i>p =</i> 0.005), there was no such link between IOP and CCT (<i>r</i> = 0.09, <i>p =</i> 0.38).</p><p><strong>Conclusion: </strong>Central cornea thickness (CCT), RNFL thickness, and IOP in isolation should not be used as early indicators for POAG; rather, a combination of these and other indices is recommended. Early detection through active screening and treatment in the community for at-risk groups is highly advised.</p><p><strong>How to cite this article: </strong>Ezinne NE, Kwarteng MA, Ekemiri KK, <i>et al</i>. Clinical Profile of Primary Open-angle Glaucoma Patients at an Eye Center in Nigeria. J Curr Glaucoma Pract 2023;17(3):113-117.</p>","PeriodicalId":15419,"journal":{"name":"Journal of Current Glaucoma Practice","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618605/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71424039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}