Jurnal Farmagazine最新文献

PENGARUH KONSENTRASI NANO-PARTIKEL PERAK HASIL BIOSINTESIS DEKOKTA KULIT MANGGIS TERHADAP MUTU FISIK SEDIAAN SERUM 生物合成脱色皮肤所产生的纳米粒子浓度的影响……对血清血清的物理质量产生了抗药性

Jurnal Farmagazine Pub Date : 2022-02-28 DOI: 10.47653/farm.v9i1.562

Z. Fanani, Yayuk Mundriyastutik, Rika Murharyanti, Bonita Anzila Desi

引用次数: 0

PENGEMBANGAN FORMULASI DAN EFEKTIVITAS SABUN CAIR WAJAH EKSTRAK BIJI ALPUKAT (Persea americana Mill) SEBAGAI ANTIJERAWAT TERHADAP BAKTERI Staphylococcus aureus 油梨籽提取物的液体肥皂配方和效力，用于对抗葡萄球菌菌

Jurnal Farmagazine Pub Date : 2022-02-28 DOI: 10.47653/farm.v9i1.597

Meta Safitri, Mohammad Zaky, Shinta Chaerani

引用次数: 1

EFEKTIVITAS TANAMAN PEPAYA (Carica papaya L.) TERHADAP PENYEMBUHAN LUKA : A NARRATIVE REVIEW 木瓜植物的效力(Carica papaya L)治疗伤口:一种叙述性评论

Jurnal Farmagazine Pub Date : 2022-02-28 DOI: 10.47653/farm.v9i1.540

Adam Syah, Puspita Septie Dianita, Herma Fanani Agusta

引用次数: 3

FORMULASI DAN UJI AKTIVITAS ANTIOKSIDAN LOTION EKSTRAK ETANOL 70% DAUN KEJI BELING (Strobilanthes crispa (L.) Blume) DENGAN METODE DPPH 提取物配方和抗氧化活性乳液70%是肮脏的白垩(草莓crispa)。用DPPH方法

Jurnal Farmagazine Pub Date : 2022-02-28 DOI: 10.47653/farm.v9i1.594

Mohammad Zaky, Dina Pratiwi, Mianah Mianah

{"title":"FORMULASI DAN UJI AKTIVITAS ANTIOKSIDAN LOTION EKSTRAK ETANOL 70% DAUN KEJI BELING (Strobilanthes crispa (L.) Blume) DENGAN METODE DPPH","authors":"Mohammad Zaky, Dina Pratiwi, Mianah Mianah","doi":"10.47653/farm.v9i1.594","DOIUrl":"https://doi.org/10.47653/farm.v9i1.594","url":null,"abstract":"Keji beling leaves (Strobilanthes crispa (L.) Blume) contain flavonoids, alkaloids and tannins. The content of flavonoid compounds found in the leaves is known to act as natural antioxidants. This study aims to determine the physical properties of the lotion and at what concentration the ethanol extract lotion 70% of keji beling leaves (Strobilanthes crispa (L.) Blume) has the most optimal activity as an antioxidant. This type of research is experimental research with descriptive analysis. The extract of the keji beling leaf was made by maceration method using 70% ethanol as a solvent. The active ingredient used in the manufacture of the lotion is the extract of the leaves of the vile leaf (Strobilanthes crispa (L.) Blume) with various concentrations of F0 0%, FI 1%, FII 2%, FIII 3% and FIV (positive control). All formulas for lotion were tested by physical evaluation including (organoleptic observation, homogeneity, viscosity, pH, dispersibility, adhesion, emulsion type o / w or w / o and hedonic) as well as testing for antioxidant activity. The results of the physical evaluation of the preparations stated that all lotion preparations met the physical quality requirements, namely brownish green, thick in shape, distinctive odor of vile leaf extract, homogeneous, viscosity 3887-6017 cps, pH 5.16.9, spreadability 5.6 -5.9 cm, adhesiveness of 5.9-6.4 seconds, the type of lotion o / w (oil in water) and the hedonic test showed that the respondents liked the attractive color, fragrant smell, and texture of the lotion. Conclusion The extract of the vicious beling leaf can be made into a lotion with various concentrations. The antioxidant activity of the lotion was determined by calculating","PeriodicalId":153904,"journal":{"name":"Jurnal Farmagazine","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125723122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

FORMULASI DAN UJI EFEKTIVITAS ANTIOKSIDAN HANDBODY LOTION EKSTRAK ETANOL 70% BUAH MENTIMUN (Cucumis sativus L.) DENGAN METODE DPPH 二十年黄瓜(学名Cucumis sativus L)。DPPH方法

Jurnal Farmagazine Pub Date : 2022-02-28 DOI: 10.47653/farm.v9i1.596

Arini Aprilliani, Jaka Supriyanta, Lailatul Badriah

{"title":"FORMULASI DAN UJI EFEKTIVITAS ANTIOKSIDAN HANDBODY LOTION EKSTRAK ETANOL 70% BUAH MENTIMUN (Cucumis sativus L.) DENGAN METODE DPPH","authors":"Arini Aprilliani, Jaka Supriyanta, Lailatul Badriah","doi":"10.47653/farm.v9i1.596","DOIUrl":"https://doi.org/10.47653/farm.v9i1.596","url":null,"abstract":"Cucumber (Cucumis sativus L.) is a natural ingredient that can be used as a health to overcome problems in beauty skin and is used as an antioxidant. Cucumber has secondary metabolites such as flavonoids, saponins, and alkaloids. This study aims to determine the IC50 value of cucumber fruit extract using the DPPH method. This type of research is experimental. Cucumber extract was made by maceration method using 70% ethanol as solvent. Cucumber extract was formulated in four handbody lotion formulations with concentrations of F0 0%, FI 0.5%, F2 1%, F3 1.5% and F4 with Vitamin C 1% as a positive control. The physical evaluation test showed results that met the physical requirements of the lotion (organoleptic, homogeneous, spreadability, adhesion, viscosity, pH, lotion type and hedonic test). Antioxidant activity of handbody lotion cucumber fruit extract with a concentration of 0.5%, 1% and 1.5% has an IC50 value of 101.019 ppm, 95.656 ppm, and 91,657 ppm respectively. The conclusion of this study that has the highest antioxidant activity is the third formula with a 1.5% concentration of 91.657 ppm.","PeriodicalId":153904,"journal":{"name":"Jurnal Farmagazine","volume":"47 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114549039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

FORMULASI DAN UJI MUTU FISIK MASKER GEL KOMBINASI EKSTRAK ETANOL HERBA PEGAGAN (Centella asiatica (L.) Urb.) DAN NIASINAMIDA DENGAN VARIASI KARBOMER 药材配方及药材质量测试凝胶的乙醇摄入量(L.)。哦。)和熔融苯甲胺

Jurnal Farmagazine Pub Date : 2022-02-28 DOI: 10.47653/farm.v9i1.576

Debby Juliadi, Rr. Asih Juanita

引用次数: 1

FORMULASI SABUN PADAT EKSTRAK ETANOL DAUN SIRIH MERAH (Piper crocatum)

Jurnal Farmagazine Pub Date : 2022-02-28 DOI: 10.47653/farm.v9i1.587

Mega Yulia, Milla Herdina, Dwi Mulyani

引用次数: 0

FORMULASI TABLET KUNYAH KOMBINASI EKSTRAK DAUN KELOR DAN KATEKIN GAMBIR DENGAN PERBEDAAN JENIS PENGIKAT 片片配方会咀嚼干叶和冈氏菌提取物的组合，以及不同种类的粘合剂

Jurnal Farmagazine Pub Date : 2022-02-28 DOI: 10.47653/farm.v9i1.578

Erni Rustiani, Kyky Widayanti, Cantika Zaddana

引用次数: 0

UJI AKTIVITAS ANTIOKSIDAN DAUN BIOLA (Ficus Lyrata Warb.) 小提琴叶抗氧化剂活性试验。

Jurnal Farmagazine Pub Date : 2022-02-28 DOI: 10.47653/farm.v9i1.553

Delta Baharyati, Komar Ruslan Wirasutisna, Rika Hartati

引用次数: 0

ANALISIS IN-SILICO PENGHAMBATAN MAIN PROTEASE (MPRO) PADA SARS-CoV-2 OLEH SENYAWA AKTIF TEH HIJAU (Camelia sinensis)

Jurnal Farmagazine Pub Date : 2021-08-30 DOI: 10.47653/FARM.V8I2.548

Rosario Trijuliamos Manalu, Harfiana Safitri, Hesti Paramita Sari, Rheamanda Devina, I. Irnawati, Eni Asmarizah Liliwana

{"title":"ANALISIS IN-SILICO PENGHAMBATAN MAIN PROTEASE (MPRO) PADA SARS-CoV-2 OLEH SENYAWA AKTIF TEH HIJAU (Camelia sinensis)","authors":"Rosario Trijuliamos Manalu, Harfiana Safitri, Hesti Paramita Sari, Rheamanda Devina, I. Irnawati, Eni Asmarizah Liliwana","doi":"10.47653/FARM.V8I2.548","DOIUrl":"https://doi.org/10.47653/FARM.V8I2.548","url":null,"abstract":"COVID-19 adalah penyakit pernapasan akibat virus yang menyebabkan keadaan darurat kesehatan global dan diumumkan sebagai penyakit pandemi oleh Organisasi Kesehatan Dunia. Kurangnya molekul obat tertentu atau strategi pengobatan untuk melawan penyakit ini membuatnya semakin parah. Oleh karena itu, molekul obat yang efektif sangat dibutuhkan untuk melawan COVID-19. Protease utama (Mpro) dari SARS CoV 2, komponen kunci dari replikasi virus ini, dianggap sebagai target utama pengembangan obat anti-COVID-19. Tujuan penelitian ini untuk mengetahui apakah senyawa yang ada di dalam tumbuhan Camellia sinensis berpotensi sebagai obat COVID-19. Jenis penelitian adalah in silico menggunakan metode molecular docking. Hasil studi ini menunjukkan bahwa dari 8 senyawa aktif, CG (Catechin gallat) dan ECG (Epicatechin gallate) menunjukkan potensi untuk diteliti lebih lanjut, karena potensi aktivitasnya lebih kuat dibandingkan dengan senyawa pembanding Remdesivir, dengan score masing-masing -111,407 dan -111.391. Selain itu juga melakukan visualisasi residu setiap senyawa yang ada pada tumbuhan Camellia sinensis dengan Reseptor SARS-CoV-2 menggunakan Webserver PLIP. Sebanyak 5 senyawa aktif dari tanaman Camellia sinensis disaring melalui penapisan berdasarkan parameter Lipinski’s Rule of Five dan prediksi ADMET menggunakan pkCSM. Potensi inhibisi SARS-CoV-2 oleh Catechin gallat dan Epicatechin gallat dari penelitian ini dapat menjadi titik awal dalam proses pengembangan obat terapi COVID-19 dari senyawa bahan alam.","PeriodicalId":153904,"journal":{"name":"Jurnal Farmagazine","volume":"66 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127213182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2