Uzun Sümeyye Gümüs , Berrin Zuhal Altunkaynak , ınsu Alkan Is
{"title":"Retraction notice to the effects of myricitrin and chebulinic acid on the rat hippocampusexposed to gamma radiation: A stereological, histochemical andbiochemical study J. Chem. Neuroanat. Volume 132, October 2023, 102305","authors":"Uzun Sümeyye Gümüs , Berrin Zuhal Altunkaynak , ınsu Alkan Is","doi":"10.1016/j.jchemneu.2024.102444","DOIUrl":"10.1016/j.jchemneu.2024.102444","url":null,"abstract":"","PeriodicalId":15324,"journal":{"name":"Journal of chemical neuroanatomy","volume":"139 ","pages":"Article 102444"},"PeriodicalIF":2.7,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0891061824000590/pdfft?md5=fbf2492899b8ce1782878b84b228487c&pid=1-s2.0-S0891061824000590-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141758934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Retraction notice to “TGN020 application against aquaporin 4 improved multiple sclerosis by inhibiting astrocytes, microglia, and NLRP3 inflammasome in a cuprizone mouse model” [J. Chem. Neuroanat. 132 (2023) 102306]","authors":"Yousef Mohamadi , Maryam Borhani-Haghighi","doi":"10.1016/j.jchemneu.2024.102445","DOIUrl":"10.1016/j.jchemneu.2024.102445","url":null,"abstract":"","PeriodicalId":15324,"journal":{"name":"Journal of chemical neuroanatomy","volume":"139 ","pages":"Article 102445"},"PeriodicalIF":2.7,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0891061824000607/pdfft?md5=923416bb3c9518d9433511555b1f76ed&pid=1-s2.0-S0891061824000607-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141758932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
William A. Noftz , Emily E. Echols , Nichole L. Beebe , Jeffrey G. Mellott , Brett R. Schofield
{"title":"Differential cholinergic innervation of lemniscal versus non-lemniscal regions of the inferior colliculus","authors":"William A. Noftz , Emily E. Echols , Nichole L. Beebe , Jeffrey G. Mellott , Brett R. Schofield","doi":"10.1016/j.jchemneu.2024.102443","DOIUrl":"10.1016/j.jchemneu.2024.102443","url":null,"abstract":"<div><p>The inferior colliculus (IC), a midbrain hub for integration of auditory information, receives dense cholinergic input that could modulate nearly all aspects of hearing. A key step in understanding cholinergic modulation is to identify the source(s) and termination patterns of cholinergic input. These issues have not been addressed for the IC in mice, an increasingly important model for study of hearing. We examined cholinergic inputs to the IC in adult male and female mice. We used retrograde tracing and immunochemistry to identify three sources of cholinergic innervation of the mouse IC: the pedunculopontine tegmental nucleus (PPT), the laterodorsal tegmental nucleus (LDT) and the lateral paragigantocellular nucleus (LPGi). We then used Cre-dependent labeling of cholinergic neurons in normal-hearing ChAT-Cre mice to selectively label the cholinergic projections to the IC from each of the cholinergic sources. Labeling of cholinergic projections from the PPT and LDT revealed cholinergic axons and boutons terminating throughout the IC, with the ipsilateral projection being denser. Electron microscopic examination showed that these cholinergic axons can form traditional synaptic junctions with IC neurons. In separate experiments, selective labeling of cholinergic projections from the LPGi revealed bilateral projections to the IC. The LPGi axons exhibited relatively equal densities on ipsilateral and contralateral sides, but on both sides the terminations were largely restricted to the non-lemniscal regions of the IC (i.e., the dorsal cortex, lateral cortex and intercollicular tegmentum). We conclude first that cholinergic axons can form traditional synapses in the IC. In addition, lemniscal and non-lemniscal regions of the IC receive different patterns of cholinergic innervation. The lemniscal IC (IC central nucleus) is innervated by cholinergic neurons in the PPT and the LDT whereas the non-lemniscal “shell” areas of the IC are innervated by the PPT and LDT and by cholinergic neurons in the LPGi.</p></div><div><h3>Data Availability</h3><p>Data will be made available on request.</p></div>","PeriodicalId":15324,"journal":{"name":"Journal of chemical neuroanatomy","volume":"139 ","pages":"Article 102443"},"PeriodicalIF":2.7,"publicationDate":"2024-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0891061824000577/pdfft?md5=0ba7fa7d7b0108c426d9a93ac7c12f45&pid=1-s2.0-S0891061824000577-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141446268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Retraction notice to “Exercise ameliorates hippocampal damage induced by Wi-Fi radiation; A biochemical, histological, and immunohistochemical study” [J. Chem. Neuroanat. 129 (2023) 102252]","authors":"","doi":"10.1016/j.jchemneu.2024.102433","DOIUrl":"10.1016/j.jchemneu.2024.102433","url":null,"abstract":"","PeriodicalId":15324,"journal":{"name":"Journal of chemical neuroanatomy","volume":"139 ","pages":"Article 102433"},"PeriodicalIF":2.7,"publicationDate":"2024-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0891061824000474/pdfft?md5=e8a2f64d8f8d3b57ce8c7bfeb429c6ae&pid=1-s2.0-S0891061824000474-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141293451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Retraction notice to “Neuroprotective potential of Ginkgo biloba on alteration of rat cerebellum following prenatal exposure to cyclophosphamide” J. Chem. Neuroanat. 130 (2023) 102268","authors":"","doi":"10.1016/j.jchemneu.2024.102434","DOIUrl":"10.1016/j.jchemneu.2024.102434","url":null,"abstract":"","PeriodicalId":15324,"journal":{"name":"Journal of chemical neuroanatomy","volume":"139 ","pages":"Article 102434"},"PeriodicalIF":2.7,"publicationDate":"2024-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0891061824000486/pdfft?md5=89ffdf67e82bf66e050afff09069e87e&pid=1-s2.0-S0891061824000486-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141293452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Herbert Major on the insula: An early depiction of von Economo neurones?","authors":"Andrew J. Larner , Lazaros C. Triarhou","doi":"10.1016/j.jchemneu.2024.102435","DOIUrl":"10.1016/j.jchemneu.2024.102435","url":null,"abstract":"<div><p>Herbert Major (1850–1921) undertook histopathological studies of human and non-human primate brains at the West Riding Lunatic Asylum in Wakefield, England, during the 1870s. Two of his papers specifically investigated the structure of the island of Reil, or insula, “with the view of ascertaining its exact structure”. In addition to describing and illustrating its lamination as six-layered, Major also identified “spindle-shaped” cells in the lower layers of human brains, but not in non-human primates. His written description, including measurements of cell body size, and illustration are suggestive that these were the neurones later described in the frontoinsular and anterior cingulate cortex by Constantin von Economo and Georg N. Koskinas and which were subsequently given the eponym “von Economo neurones”. von Economo noted that this special neuronal type had been previously seen by <span>Betz (1881)</span>, <span>Hammarberg (1895)</span>, and <span>Ramón y Cajal (1899-1904)</span>, but he did not mention Major’s works. Major also ascribed linguistic functions to the insula. Hence, with respect to both anatomical and physiological features, Major may have pre-empted the findings of later research on this structure.</p></div>","PeriodicalId":15324,"journal":{"name":"Journal of chemical neuroanatomy","volume":"138 ","pages":"Article 102435"},"PeriodicalIF":2.8,"publicationDate":"2024-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141186535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impacts of SARS-CoV-2 on brain renin angiotensin system related signaling and its subsequent complications on brain: A theoretical perspective","authors":"Negar Etebar , Saghi Naderpour , Setareh Akbari , Alireza Zali , Meisam Akhlaghdoust , Seyed Mojtaba Daghighi , Matin Baghani , Seyed Hootan Hamidi , Milad Rahimzadegan","doi":"10.1016/j.jchemneu.2024.102423","DOIUrl":"10.1016/j.jchemneu.2024.102423","url":null,"abstract":"<div><p>Cellular ACE2 (cACE2), a vital component of the renin–angiotensin system (RAS), possesses catalytic activity to maintain AngII and Ang 1–7 balance, which is necessary to prevent harmful effects of AngII/AT2R and promote protective pathways of Ang (1−7)/MasR and Ang (1–7)/AT2R. Hemostasis of the brain–RAS is essential for maintaining normal central nervous system (CNS) function. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a viral disease that causes multi-organ dysfunction. SARS-CoV-2 mainly uses cACE2 to enter the cells and cause its downregulation. This, in turn, prevents the conversion of Ang II to Ang (1−7) and disrupts the normal balance of brain–RAS. Brain–RAS disturbances give rise to one of the pathological pathways in which SARS-CoV-2 suppresses neuroprotective pathways and induces inflammatory cytokines and reactive oxygen species. Finally, these impairments lead to neuroinflammation, neuronal injury, and neurological complications. In conclusion, the influence of RAS on various processes within the brain has significant implications for the neurological manifestations associated with COVID-19. These effects include sensory disturbances, such as olfactory and gustatory dysfunctions, as well as cerebrovascular and brain stem-related disorders, all of which are intertwined with disruptions in the RAS homeostasis of the brain.</p></div>","PeriodicalId":15324,"journal":{"name":"Journal of chemical neuroanatomy","volume":"138 ","pages":"Article 102423"},"PeriodicalIF":2.8,"publicationDate":"2024-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140855320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ahmet Payas , Emre Bal , Duygu Ekinci , Sabri Batın
{"title":"The effect of spinal correction surgery on the tractography data of the pain pathway in scoliosis patients: a preliminary report","authors":"Ahmet Payas , Emre Bal , Duygu Ekinci , Sabri Batın","doi":"10.1016/j.jchemneu.2024.102432","DOIUrl":"10.1016/j.jchemneu.2024.102432","url":null,"abstract":"<div><h3>Study design</h3><p>Cross-sectional study.</p></div><div><h3>Objective</h3><p>Pain in individuals with opered scoliosis is usually evaluated with a postural analysis or questionnaire. In this study, we evaluated pain in individuals with scoliosis who underwent spinal correction surgery by tractography and compared it with individuals with non-opered scoliosis and healthy individuals.</p></div><div><h3>Design</h3><p>Fifteen healthy individuals, 15 non-operated scoliosis patients and 15 operated scoliosis patients were included in the study.</p></div><div><h3>Methods</h3><p>All female participants in this prospectively planned study used their right hand as the dominant hand. Bilateral tractography analysis of the pain pathways was performed with DSI Studio software using brain magnetic resonance images (MRI) of the participants. Statistical analysis of the study was performed with IBM SPSS 23.0 and p<0.05 values were considered significant.</p></div><div><h3>Results</h3><p>It was observed that the tractography values of the operated scoliosis group were similar to the control group (p˃0.05). In the non-operated scoliosis group, tractography findings related to nerve conduction velocity such as fiber count, fiber ratio and axial diffusivity (AD) were found to be higher than the other two groups (p<0.05). Fractional anisotropy (FA) values of the unoperated scoliosis group were significantly different between the pain pathways projected from the right/left side of the body (p<0.05).</p></div><div><h3>Conclusion</h3><p>The fact that the pain path tractography values of patients with scoliosis who underwent surgery were similar to those of healthy individuals may be evidence of decreased pain sensation reaching the brain. Surgery may be a good choice in the treatment of pain in patients with scoliosis.</p></div>","PeriodicalId":15324,"journal":{"name":"Journal of chemical neuroanatomy","volume":"138 ","pages":"Article 102432"},"PeriodicalIF":2.8,"publicationDate":"2024-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140862619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Corrigendum to “Therapeutic effects of melatonin-treated bone marrow mesenchymal stem cells (BMSC) in a rat model of Alzheimer's disease” [J. Chem. Neuroanat. 108 (2020) 101804]","authors":"Mahdi Ramezani , Alireza Komaki , Nasrin Hashemi-Firouzi , Keywan Mortezaee , Nafiseh Faraji , Zoleikha Golipoor","doi":"10.1016/j.jchemneu.2024.102425","DOIUrl":"https://doi.org/10.1016/j.jchemneu.2024.102425","url":null,"abstract":"","PeriodicalId":15324,"journal":{"name":"Journal of chemical neuroanatomy","volume":"138 ","pages":"Article 102425"},"PeriodicalIF":2.8,"publicationDate":"2024-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0891061824000383/pdfft?md5=363c5efe21862cbd4c7c2415be428b1c&pid=1-s2.0-S0891061824000383-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140644649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}