中药材最新文献_第3页

[Chemical Constituents from Przewalskia tangutica]. [来自普氏原羚的化学成分]。

Journal of Chinese medicinal materials Pub Date : 2016-09-01

Zhuo-ma Da-Wa, Min Zhao, Da-le Guo, Dong-mei Fang, Yan Zhou

引用次数: 0

[Metabolism Changes of Main Active Ingredients During Liquid Fermentation of Cordyceps militaris]. [蛹虫草液体发酵过程中主要活性成分代谢变化]。

Journal of Chinese medicinal materials Pub Date : 2016-09-01

Ling-jie Cao, Xue-mei Lu, Xiao-bao Jin, Jia-yong Zhu

{"title":"[Metabolism Changes of Main Active Ingredients During Liquid Fermentation of Cordyceps militaris].","authors":"Ling-jie Cao, Xue-mei Lu, Xiao-bao Jin, Jia-yong Zhu","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To study the accumulation and changes of main active ingredients during liquid fermentation of Cordyceps militaris.Methods: The militaris varity GIM5. 270 was selected to extended fermentation time to 20 days on the basic fermentation condition. Meanwhile, the accumulation and dynamic changes of biomass, polysaccharide, cordycepic acid, adenosine and cordycepin in the fermentation system were detected by the analytical method of contents per 24 hour.Results: The foundation culture medium composed of complex nitrogen sources could reach a higher biomass level than single nitrogen sources. In addition, with the development of time, the mycelial biomass increased, the contents of polysaccharide and cordycepic acid( D-mannitol) increased firstly and then decreased, the contents of adenosine decreased gradually and cordycepin( 3-deoxy adenosine) increased gradually.Conclusion: The whole system is observed autolyzed phenomenon caused by absorbing self-generated nutrients. In this study, the dynamic changes of the main active ingredients in the fermentation system are researched and the optimum collecting time is determined, which provides evidence for reaching a better yield of the active ingredients.","PeriodicalId":15312,"journal":{"name":"Journal of Chinese medicinal materials","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36484400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Effects of the Saponins from Panax japonicus on Intestinal Epithelial Tight Junction Proteins in Aging Rats]. [参总皂苷对衰老大鼠肠上皮紧密连接蛋白的影响]。

Journal of Chinese medicinal materials Pub Date : 2016-09-01

Hai-ying Wang, Yao-yan Dun, Ding Yuan, Min Liu, Yu-hui Guo, Chang-cheng Zhang

{"title":"[Effects of the Saponins from Panax japonicus on Intestinal Epithelial Tight Junction Proteins in Aging Rats].","authors":"Hai-ying Wang, Yao-yan Dun, Ding Yuan, Min Liu, Yu-hui Guo, Chang-cheng Zhang","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To investigate the moderating effects of total saponins of Panax japonicus on intestinal epithelial tight junction proteins in aging rats,and to explore the potential mechanism.Methods: SD rats were divided into adult group( 6 months),old model group( 24 months),and different doses( 10,30 and 60 mg / kg) of total saponins of Panax japonicus treatment groups. Levels of tight junction proteins( Occludin and ZO-1),anti-oxidative pathway proteins( Nrf2、HO-1 and NQO-1),mitochondrial biogenesis related proteins( Sirt1 and PGC-1α) and p-AMPK in the ileum were determined by immunohistochemistry staining.Results: Compared with adult group,the expressions of Occludin,ZO-1,Nrf2,HO-1,NQO-1,Sirt1 and PGC-1α of aging rats were obviously decreased( P < 0. 01),and p-AMPK was inhibited in the ileum of aging rats. Compared with aging model rats,total saponins of Panax japonicus increased the expressions of Occludin,ZO-1,Nrf2,HO-1,NQO-1,Sirt1 and PGC-1α( P < 0. 05 or P < 0. 01),and activated p-AMPK in the ileum of aging rats.Conclusion: The decreased level of intestinal tight junction proteins in the ileum of aging rats may be related to oxidative stress. Total saponins of Panax japonicus can up-regulate the level of intestinal tight junction proteins to improve the intestinal mucosal barrier dysfunction in the ileum of aging rat via reducing the levels of oxidative stress.","PeriodicalId":15312,"journal":{"name":"Journal of Chinese medicinal materials","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36486636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Identification on Five Kinds of Easily Confused Bupleurum Medicinal Materials]. 【柴胡属五种易混淆药材鉴别】。

Journal of Chinese medicinal materials Pub Date : 2016-09-01

{"title":"[Identification on Five Kinds of Easily Confused Bupleurum Medicinal Materials].","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"Objective: Macroscopic identification, thin layer chromatography( TLC) identification and molecular identification based on the Chinese Pharmacopoeia were established to identify five kinds of Bupleurum medicinal materials such as Bupleurum chinense,Bupleurum scorzonerifolium, Bupleurum marginatum, Bupleurum marginatum var. stenophyllum and Bupleurum bicaule,which were easily confused.Methods: According to the Chinese Pharmacopoeia,macroscopic characters of these five kinds of Bupleurum medicinal materials were observed and described; TLC identification method with saikosaponin d and control medicinal material of Bupleuri Radix as reference substances was established. Furthermore, DNA barcode was applied in identification of these confused drugs.Results: Five Bupleurum medicinal materials could be easily distinguished by their morphological characters. Moreover, TLC of Bupleurum chinense,Bupleurum scorzonerifolium, Bupleurum marginatum and Bupleurum marginatum var. stenophyllum were extremely similar while being different from that of Bupleurum bicaule. The ITS2 sequences could be used to identify the five Bupleurum medicinal materials.Conclusion: The established macroscopic identification and TLC for distinguishing of the five kinds of Bupleurum medicinal materials are simple and accurate while DNA barcode technology being effective and extensive. Besides, this study provides scientific basis for the further pharmacodynamic studies on Bupleurum marginatum and Bupleurum marginatum var. stenophyllum.","PeriodicalId":15312,"journal":{"name":"Journal of Chinese medicinal materials","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36484398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Comparative Study on the Four Kinds of Flavonoids from Four Different Varieties of Dendranthema morifolium]. [4个不同品种菊花中4种黄酮类化合物的比较研究]。

Journal of Chinese medicinal materials Pub Date : 2016-09-01

Han-zhen Liu, Ya-dong Shi, Hao Yu, Xin Xiao, Bin-bin Mao, Yan-xi Fang, Guo-liang Zhou

{"title":"[Comparative Study on the Four Kinds of Flavonoids from Four Different Varieties of Dendranthema morifolium].","authors":"Han-zhen Liu, Ya-dong Shi, Hao Yu, Xin Xiao, Bin-bin Mao, Yan-xi Fang, Guo-liang Zhou","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To establish a high phase liquid chromatography method of the content in quercetin,luteolin,apigenin,acacetin,and to compare the difference of content from four different varieties of Dendranthema morifolium in simultaneously.Methods: The UPLC methods were adopted,and the chromatographic column was Waters ACQUITYUPLC; the column was BEH C18（ 50 mm ×2. 1 mm,1. 7 μm）,the mobile phase was 0. 1% phosphoric acid solution-methanol in gradient elution,the flow rate was 0. 2 m L/min;and the detection wavelength was set at 320 nm; the column temperature 25 ℃; and the sample quantity was 1 μL.Results: In the range of 0. 0027 0. 0135 mg/m L（ r1= 0. 9962） concentration within quercetin in a good linear relationship between peak area. In the range of0. 0032 0. 0160 mg/m L（ r2= 0. 9963） concentration within luteolin in a good linear relationship between peak area. In the range of0. 0029 0. 0145 mg/m L（ r3= 0. 9964） of apigenin in the mass concentration and the peak area. In the range of 0. 0029 0. 0145 mg/m L（ r4= 0. 9963） concentration within acacetin in a good linear relationship between peak area.Conclusion: This method can be determined daisy quercetin,luteolin,apigenin,acacetin content in Dendranthema morifolium.","PeriodicalId":15312,"journal":{"name":"Journal of Chinese medicinal materials","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36487685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Correlation Between Index Components and Climatic Factors of Pseudostellariae Radix]. [伪参指标成分与气候因子的相关性]。