2013 39th Annual Northeast Bioengineering Conference最新文献_第4页

ChitO2-Clot: A Novel Hemostatic and Oxygen Releasing Biomaterial for Traumatic Injuries 壳氧凝块:一种新型的创伤止血释氧生物材料

2013 39th Annual Northeast Bioengineering Conference Pub Date : 2013-04-05 DOI: 10.1109/NEBEC.2013.67

G. Ulsh, Dung Le, J. Moy, M. McDermott, G. Collins

{"title":"ChitO2-Clot: A Novel Hemostatic and Oxygen Releasing Biomaterial for Traumatic Injuries","authors":"G. Ulsh, Dung Le, J. Moy, M. McDermott, G. Collins","doi":"10.1109/NEBEC.2013.67","DOIUrl":"https://doi.org/10.1109/NEBEC.2013.67","url":null,"abstract":"ChitO2-Clot is a novel hemostatic wound dressing. ChitO2-Clot will help facilitate coagulation/clot formation as well as providing oxygen to the wound, all while being cost effective and competitive with current hemostatic dressings. The product is composed of a micro/nano sized fibrous mat made of chitosan that is doped with Perfluorocarbons (oxygen carrier). The user would pack a hemorrhaging wound with ChitO2-Clot in order to stop the bleeding. The chitosan in ChitO2-Clot rapidly absorbs the blood in the wound bed and forms a gelatinous clot that fills the empty void of the wound. The gelatinous clot filling this void in the tissue applies pressure to the damaged vasculature, which prevents further bleeding. Chitosan also activates the clot clotting cascade and causes the agglutination of red blood cells, accelerates coagulation in vivo by influencing the activation of platelets. The Perfluorocarbons (oxygen career) release oxygen into the wound bed to help facilitate the wound healing process. Over time, the chitosan in ChitO2-Clot will be reabsorbed by the body and converted into sugar, while the Perfluorocarbon (PFC) is expelled via gas exchange in the lungs.","PeriodicalId":153112,"journal":{"name":"2013 39th Annual Northeast Bioengineering Conference","volume":"221 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121350820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Near Infrared Spectroscopy as a Method for Non-Destructive Monitoring of Engineered Cartilage Growth 近红外光谱法无损监测工程软骨生长

2013 39th Annual Northeast Bioengineering Conference Pub Date : 2013-04-05 DOI: 10.1109/NEBEC.2013.119

Michael Shockley, C. Mcgoverin, U. Palukuru, Padraig B. M. Glenn, N. Pleshko, Richard Spencer

引用次数: 1

A Novel Technique to Remove Bone Cement in Reoperative Revision Knee Arthroplasty 再手术翻修膝关节置换术中一种去除骨水泥的新技术

2013 39th Annual Northeast Bioengineering Conference Pub Date : 2013-04-05 DOI: 10.1109/NEBEC.2013.43

M. Aguas, W. Dannhauser, R. Fox, M. Scalzi, S. Verdi

引用次数: 1

Rheological Analysis of Hydrogel Composites Containing Carbon Nanobrushes 含碳纳米刷的水凝胶复合材料流变学分析

2013 39th Annual Northeast Bioengineering Conference Pub Date : 2013-04-05 DOI: 10.1109/NEBEC.2013.134

W. Marks, Tunc Kiymaz, Sze C. Yang, G. Dombi, S. Bhatia

{"title":"Rheological Analysis of Hydrogel Composites Containing Carbon Nanobrushes","authors":"W. Marks, Tunc Kiymaz, Sze C. Yang, G. Dombi, S. Bhatia","doi":"10.1109/NEBEC.2013.134","DOIUrl":"https://doi.org/10.1109/NEBEC.2013.134","url":null,"abstract":"The objective of this work is to examine the rheological properties of hydrogel comosites containing carbon nanobrushes. The composite, which is electrically conductive, is comprised of carbon nanobrushes embedded in a biocompatible poloxamer gel. This work assesses the ability of such composite gels to act as a matrix for tissue engineering, specifically for connective tissue. In such a model, chondrocytes would be seeded within the hydrogel matrix and then injected into the body. This work analyzes the rheological differences between hydrogels of different concentrations. The work also demonstrates that carbon nanobrushes can be dispersed within poloxamer gels. Previously it has been shown that fibroblasts and myocytes can proliferate within homogenously dispersed carbon nanobrush-containing poloxamer gels. Future work will examine the effects of design parameters including carbon nanobrush content and matrix structure on wound healing, chondrocyte proliferation within the hydrogel composites, and mechanical properties of the gels. This work has relevance for tissue engineering and tissue regeneration in clinical medicine.","PeriodicalId":153112,"journal":{"name":"2013 39th Annual Northeast Bioengineering Conference","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114338170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reduction in Resorption Cavity Size following Anti-Resorptive Drug Treatment 抗吸收药物治疗后吸收腔大小的减少

2013 39th Annual Northeast Bioengineering Conference Pub Date : 2013-04-05 DOI: 10.1109/NEBEC.2013.165

Jonathan B. Matheny, Craig R. Slyfield, E. V. Tkachenko, I. Lin, Amanda R. Bouman, K. M. Ehlert, C. Hernandez, R. Tomlinson, D. Wilson

{"title":"Reduction in Resorption Cavity Size following Anti-Resorptive Drug Treatment","authors":"Jonathan B. Matheny, Craig R. Slyfield, E. V. Tkachenko, I. Lin, Amanda R. Bouman, K. M. Ehlert, C. Hernandez, R. Tomlinson, D. Wilson","doi":"10.1109/NEBEC.2013.165","DOIUrl":"https://doi.org/10.1109/NEBEC.2013.165","url":null,"abstract":"Raloxifene treatment increases bone strength more than would be expected from changes in bone mass or bone turnover A possible mechanism through which raloxifene treatment increases bone strength independent of bone mass and bone turnover is by reducing the size of resorption cavities formed during bone remodeling. A novel three-dimensional dynamic bone histomorphometry approach was used to determine the effects of raloxifene treatment on the threedimensional size of individual bone remodeling events (both resorption cavities and subsequent bone formation events) in cancellous bone using an ovariectomized rat model. Raloxifene treated animals were found to have reduced cavity volume and maximum cavity depth compared to both ovariectomized and sham control groups. Sham control and raloxifene treated animals also have reduced formation event size compared to OVX animals. Raloxifene leads to reduced size of remodeling events compared to ovariectomized and sham controls. Differences in cavity size may influence subsequent bone biomechanical performance independent of bone turnover.","PeriodicalId":153112,"journal":{"name":"2013 39th Annual Northeast Bioengineering Conference","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115265585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Smart-Pan: Bedpan Management System 智能便盆:便盆管理系统

2013 39th Annual Northeast Bioengineering Conference Pub Date : 2013-04-05 DOI: 10.1109/NEBEC.2013.139

N. T. Faulkner, J. Lacourse, R. Shippee-Rice

引用次数: 0

Development and Study of a Hybrid Tissue Scaffold Fabrication System for Neurotrophin Delivery 神经营养因子输送混合组织支架制造系统的开发与研究

2013 39th Annual Northeast Bioengineering Conference Pub Date : 2013-04-05 DOI: 10.1109/NEBEC.2013.79

V. P. Jani, R. Patel, R. K. Reddy, L. Zhang, C. T. Wagner, C. Yan

引用次数: 1

Preparation of Nanotubular PDMS/PVC Molds for Reduced Catheter Inflammation and Infection 用于减少导管炎症和感染的纳米管PDMS/PVC模具的制备

2013 39th Annual Northeast Bioengineering Conference Pub Date : 2013-04-05 DOI: 10.1109/NEBEC.2013.128

Luting Liu, T. Webster

引用次数: 1

Using myDAQ and LabVIEW to Develop a Single-Channel EEG for a Multi-modality Epileptic Seizure Detection Platform 利用myDAQ和LabVIEW开发用于多模态癫痫发作检测平台的单通道脑电图

2013 39th Annual Northeast Bioengineering Conference Pub Date : 2013-04-05 DOI: 10.1109/NEBEC.2013.35

David Wang, L. Khuon

引用次数: 6

Activity Analyzer for Guided Independent Living Environments (AAGILE) 引导独立生活环境活动分析仪(AAGILE)

2013 39th Annual Northeast Bioengineering Conference Pub Date : 2013-04-05 DOI: 10.1109/NEBEC.2013.47

Tanya Wang, Josh Harvey, E. Chabot, Ying Sun, P. Burbank

引用次数: 3