Journal of Cancer Survivorship最新文献

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A mixed methods study of adolescent and young adult cancer survivors and their utilization of a survivorship clinic: Barriers and facilitators. 青少年和青年癌症幸存者的混合方法研究及其对幸存者诊所的利用:障碍和促进因素。
IF 3.4 2区 医学
Journal of Cancer Survivorship Pub Date : 2026-09-18 DOI: 10.1007/s11764-026-02125-y
Jean C Yi, Sheri Ballard, Emily Jo Artim, Casey Walsh, K Scott Baker
{"title":"A mixed methods study of adolescent and young adult cancer survivors and their utilization of a survivorship clinic: Barriers and facilitators.","authors":"Jean C Yi, Sheri Ballard, Emily Jo Artim, Casey Walsh, K Scott Baker","doi":"10.1007/s11764-026-02125-y","DOIUrl":"https://doi.org/10.1007/s11764-026-02125-y","url":null,"abstract":"<p><strong>Purpose: </strong>The National Standards for Cancer Survivorship Care propose health system policies to develop survivorship programs. Little is known about the utilization, barriers, and facilitators of survivorship care amongst adolescent and young adult (AYA: ages 15-39 at diagnosis) cancer survivors.</p><p><strong>Methods: </strong>Participants included AYAs who were 1-5 years post-treatment and eligible to participate in a parent study testing a digital health intervention. The electronic health record (EHR) was queried to determine who had been seen in the Survivorship Clinic, and qualitative interviews were conducted with a randomly selected subset of those participants.</p><p><strong>Results: </strong>Of 836 survivors eligible for the parent trial, only 38 (4.5%) were seen in the Survivorship Clinic (86.8% female, 71.1% White, 86.8% not Hispanic, 65.7% breast cancer). A subset enrolled in the parent trial (n = 147) was screened for approach for qualitative interviews. Forty interviews were completed (mean age = 38.4 (SD = 4.4), 50% breast cancer, 78% female, 83% White, 83% Non-Hispanic White, 92% college or more education) with only one seen in the Survivorship Clinic. Participants identified barriers including lack of awareness, avoidance, and lack of time. Referrals from care teams, information about services provided, and telehealth were identified as factors that would have facilitated them seeking survivorship care.</p><p><strong>Conclusions: </strong>Few AYAs sought survivorship services that could assist them in addressing the late effects of their cancer diagnosis and treatment.</p><p><strong>Implications for cancer survivors: </strong>Lack of awareness of the survivorship clinic was the most significant barrier, and a referral from their oncology care team would have facilitated them scheduling a visit.</p>","PeriodicalId":15284,"journal":{"name":"Journal of Cancer Survivorship","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149001972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Contextual assessment of perceived health system alignment with National Standards for Cancer Survivorship Care in the American Southeast. 感知卫生系统与美国东南部癌症生存护理国家标准的一致性背景评估。
IF 3.4 2区 医学
Journal of Cancer Survivorship Pub Date : 2026-09-15 DOI: 10.1007/s11764-026-02123-0
Shirley M Bluethmann, Stephanie Bunch, Chandylen Nightingale, Alana R Willis, Beth York, Beth Fisher, Sarah A Birken, Rachel Zimmer, Carla Strom, Ashley Strahley, Sarah Zakrzewski, Stephanie J Sohl
{"title":"Contextual assessment of perceived health system alignment with National Standards for Cancer Survivorship Care in the American Southeast.","authors":"Shirley M Bluethmann, Stephanie Bunch, Chandylen Nightingale, Alana R Willis, Beth York, Beth Fisher, Sarah A Birken, Rachel Zimmer, Carla Strom, Ashley Strahley, Sarah Zakrzewski, Stephanie J Sohl","doi":"10.1007/s11764-026-02123-0","DOIUrl":"10.1007/s11764-026-02123-0","url":null,"abstract":"<p><strong>Purpose: </strong>We assessed perceived alignment of a large health system in the American Southeast with the National Standards for Cancer Survivorship Care (National Standards).</p><p><strong>Methods: </strong>We engaged key partners and distributed an electronic survey to oncology practices within the system. In parallel, in four representative clinics we collected qualitative data including four clinic observations and 12 semi structured interviews informed by the Consolidated Framework for Implementation Research (CFIR).</p><p><strong>Results: </strong>Of the 51 informants at practices who received the survey, 16 consented, and 10 completed at least one item. On average, informants reported meeting 55% of the survivorship care National Standards at least some of the time. Facilitators and barriers for National Standards implementation were identified in these CFIR Domains: Characteristics of the Individuals (e.g., believed to be beneficial for improving and standardizing care), Outer Setting (e.g., need to be linked to an incentive), Inner Setting (e.g., need for more provider training on what is available), Intervention Characteristics (e.g., difficult to understand), and Process (e.g., important decision-makers).</p><p><strong>Conclusions: </strong>While most informants reported meeting at least half of the National Standards, there was variability in how consistently National Standards were perceived as applied across practices. Further, there was likely bias, with more favorable responses from those who chose to complete the survey than those who did not.</p><p><strong>Implications for cancer survivors: </strong>These data demonstrate a systematic approach for assessing alignment with National Standards and identifying opportunities for improving survivorship care. A model that combines standardized survivorship services with flexibility to meet local population needs may help reduce gaps in care, promote equitable access to supportive resources, and enhance outcomes for cancer survivors across diverse settings.</p>","PeriodicalId":15284,"journal":{"name":"Journal of Cancer Survivorship","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148976860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lived experience leadership in cancer research: a scoping review of conceptual definitions, roles, responsibilities, and impacts. 癌症研究中的生活经验领导:概念定义、角色、责任和影响的范围审查。
IF 3.4 2区 医学
Journal of Cancer Survivorship Pub Date : 2026-09-14 DOI: 10.1007/s11764-026-02119-w
C E Schilstra, A Glinatsis, M Emery, B Zebrack, C K Cheung, A Smith, U M Sansom-Daly
{"title":"Lived experience leadership in cancer research: a scoping review of conceptual definitions, roles, responsibilities, and impacts.","authors":"C E Schilstra, A Glinatsis, M Emery, B Zebrack, C K Cheung, A Smith, U M Sansom-Daly","doi":"10.1007/s11764-026-02119-w","DOIUrl":"https://doi.org/10.1007/s11764-026-02119-w","url":null,"abstract":"<p><strong>Background: </strong>The meaningful integration of lived experience expertise into cancer research is increasingly recognized as essential to improving research relevance, quality, and impact. However, the extent to which people with lived experience of cancer hold leadership roles within academic research remains unclear. This scoping review examined how lived experience leadership is conceptualized, enacted, and reported in cancer research.</p><p><strong>Methods: </strong>Following PRISMA-ScR guidelines, searches were conducted in Google Scholar, PsycINFO, PubMed, and EMBASE (2015-2025). Eligible publications were peer-reviewed, English-language cancer research articles that described lived experience involvement beyond consultative/participatory methods.</p><p><strong>Results: </strong>Twelve publications were included, mostly from the UK and the USA, and focused on adult cancer. Lived experience leadership was typically framed as involvement of \"co-researchers\" who provided feedback on study documents, advised on patient-facing materials, and contributed to dissemination activities. Four publications described lived experience researchers in substantive leadership roles, and two employed the concept of the \"embodied researcher\"-described as individuals who draw upon both lived and academic expertise to lead research.</p><p><strong>Conclusions: </strong>Lived experience leadership in cancer research remains inconsistently defined and uncommonly reported. Advancing the lived experience leadership in cancer research, and recognition of this leadership, will require clearer frameworks, infrastructure, and recognition of researcher positionality to enable genuine lived experience leadership.</p><p><strong>Implications for cancer survivors: </strong>This review highlights that while lived experience is increasingly valued in cancer research, survivors are still rarely involved as substantive leaders of cancer research. Strengthening pathways for survivor leadership could help ensure that cancer research is more relevant, equitable, and responsive.</p>","PeriodicalId":15284,"journal":{"name":"Journal of Cancer Survivorship","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148968860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advancing the national standards for cancer survivorship care: overview, early implementation insights, and future directions. 推进癌症生存护理的国家标准:概述、早期实施见解和未来方向。
IF 3.4 2区 医学
Journal of Cancer Survivorship Pub Date : 2026-09-12 DOI: 10.1007/s11764-026-02122-1
Kimberly A Miller, Vida A Passero, Michelle A Mollica
{"title":"Advancing the national standards for cancer survivorship care: overview, early implementation insights, and future directions.","authors":"Kimberly A Miller, Vida A Passero, Michelle A Mollica","doi":"10.1007/s11764-026-02122-1","DOIUrl":"https://doi.org/10.1007/s11764-026-02122-1","url":null,"abstract":"","PeriodicalId":15284,"journal":{"name":"Journal of Cancer Survivorship","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148955789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effect of mindfulness-based cognitive therapy on sexual self-esteem in women with breast cancer after mastectomy: a randomized controlled trial. 正念认知疗法对乳房切除术后乳腺癌患者性自尊的影响:一项随机对照试验。
IF 3.4 2区 医学
Journal of Cancer Survivorship Pub Date : 2026-09-11 DOI: 10.1007/s11764-026-02069-3
Sareh Khosravi-Khorram, Parvaneh Mousavi, Maryam Gholamzadeh-Jofreh, Mohammad-Hosein Haghighizadeh
{"title":"The effect of mindfulness-based cognitive therapy on sexual self-esteem in women with breast cancer after mastectomy: a randomized controlled trial.","authors":"Sareh Khosravi-Khorram, Parvaneh Mousavi, Maryam Gholamzadeh-Jofreh, Mohammad-Hosein Haghighizadeh","doi":"10.1007/s11764-026-02069-3","DOIUrl":"https://doi.org/10.1007/s11764-026-02069-3","url":null,"abstract":"<p><strong>Purpose: </strong>Mastectomy often leads to decreased sexual self-esteem in women with breast cancer. This study aimed to evaluate the effect of Mindfulness-Based Cognitive Therapy (MBCT) on sexual self-esteem in women after mastectomy.</p><p><strong>Methods: </strong>This randomized controlled trial (February-May 2024, Golestan Hospital, Ahvaz, Iran) enrolled 45 women aged 30-49 years after mastectomy. They were randomly assigned to an MBCT group (n = 22, eight weekly sessions) or a control group (n = 23, usual care). Sexual self-esteem was measured using the SSEI‑W‑SF at baseline and post-intervention. Data were analyzed using t‑tests and ANCOVA.</p><p><strong>Results: </strong>No baseline differences were found between groups. Post-intervention, after controlling for confounders, the MBCT group showed significantly higher scores in total sexual self-esteem and subscales (attractiveness, experience/skills, control, adaptation) compared to controls (p < 0.001, η<sup>2</sup> = 0.786). Moral judgment improved within the MBCT group (p < 0.001), but no significant between-group difference was observed (p = 0.106). The mean sexual self-esteem score was significantly higher in the MBCT group (145.95 ± 8.15) than controls (124.34 ± 10.09; p < 0.001). ANCOVA confirmed the intervention effect.</p><p><strong>Conclusions: </strong>MBCT significantly improves sexual self-esteem and its components in women post-mastectomy. Integrating MBCT into survivorship care may address an overlooked aspect of breast cancer recovery.</p><p><strong>Implications for cancer survivors: </strong>MBCT is an effective non-pharmacological intervention for improving sexual self-esteem in women after mastectomy, enhancing their quality of life.</p><p><strong>Trial registration: </strong>IRCT20231128060209N1 (registered February 5, 2024).</p>","PeriodicalId":15284,"journal":{"name":"Journal of Cancer Survivorship","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148944642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between daily step counts and frailty trajectory classes in lung cancer patients undergoing radiotherapy: a prospective longitudinal study. 接受放疗的肺癌患者每日步数与衰弱轨迹类别之间的关系:一项前瞻性纵向研究。
IF 3.4 2区 医学
Journal of Cancer Survivorship Pub Date : 2026-09-10 DOI: 10.1007/s11764-026-02117-y
Jiang Zhang, Jiang Wu, Song Li, Xiaoyan Wu, Lingyun Ran, Xijuan Zhao
{"title":"Association between daily step counts and frailty trajectory classes in lung cancer patients undergoing radiotherapy: a prospective longitudinal study.","authors":"Jiang Zhang, Jiang Wu, Song Li, Xiaoyan Wu, Lingyun Ran, Xijuan Zhao","doi":"10.1007/s11764-026-02117-y","DOIUrl":"https://doi.org/10.1007/s11764-026-02117-y","url":null,"abstract":"<p><strong>Purpose: </strong>To characterize frailty trajectories in patients undergoing radiotherapy with lung cancer, identify factors associated with trajectory membership, and examine the association between daily step counts and frailty trajectories during radiotherapy.</p><p><strong>Methods: </strong>In this prospective longitudinal study, daily step counts were collected via the WeChat Step Mini-program from the start to the end of radiotherapy. Frailty was assessed via the Frailty Phenotype Scale before radiotherapy, at the end of radiotherapy, and 1 month after radiotherapy. Latent class growth modeling was used to identify frailty-trajectory classes, and multinomial logistic regression was used to examine associated factors and the relationship between step counts and trajectory membership.</p><p><strong>Results: </strong>Among 327 patients, three frailty trajectories were identified: prefrailty declining (56.58%), frailty stable increasing (27.83%), and severe frailty increasing (15.60%) group. After adjustment for demographic and clinical covariates, higher average daily step counts during radiotherapy were independently associated with a lower likelihood of membership in adverse frailty trajectories.</p><p><strong>Conclusions: </strong>Frailty trajectories in patients with lung cancer undergoing radiotherapy were heterogeneous. Step-count gradients were observed around 3000, 6000, and 9000 steps/day, suggesting exploratory thresholds for different frailty-risk intervals.</p><p><strong>Implications for cancer survivors: </strong>Daily step counts are a scalable real-world metric. Combining continuous step monitoring with routine frailty screening may support early identification of high-risk patients and proactive, individualized management during and after radiotherapy.</p>","PeriodicalId":15284,"journal":{"name":"Journal of Cancer Survivorship","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148930045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Buffering the burden: health behaviors, mental distress, and sex disparities in U.S. cancer caregivers. 减轻负担:美国癌症护理人员的健康行为、精神困扰和性别差异。
IF 3.4 2区 医学
Journal of Cancer Survivorship Pub Date : 2026-09-09 DOI: 10.1007/s11764-026-02120-3
Areesh Mevawalla, Azza Sarfraz, Qaidar Alizai, Meher Angez, Rabia Bega, Muhammad Qasim Chaudhry, Ajia Ashraf, Abdulaziz Elemosho, Odysseas P Chatzipanagiotou, Timothy M Pawlik
{"title":"Buffering the burden: health behaviors, mental distress, and sex disparities in U.S. cancer caregivers.","authors":"Areesh Mevawalla, Azza Sarfraz, Qaidar Alizai, Meher Angez, Rabia Bega, Muhammad Qasim Chaudhry, Ajia Ashraf, Abdulaziz Elemosho, Odysseas P Chatzipanagiotou, Timothy M Pawlik","doi":"10.1007/s11764-026-02120-3","DOIUrl":"https://doi.org/10.1007/s11764-026-02120-3","url":null,"abstract":"<p><strong>Purpose: </strong>Cancer caregivers experience heightened psychological distress, yet the cumulative impact of modifiable health behaviors on mental distress remains understudied. We evaluated the association between individual and cumulative protective factors and frequent mental distress (FMD) among U.S. cancer and non-cancer caregivers.</p><p><strong>Methods: </strong>A cross-sectional analysis was conducted using data from the 2022 BRFSS data. Adult caregivers were identified and classified according to whether the individual provided care to an individual with cancer. FMD was defined as ≥ 14 days of poor mental health in the past 30 days. Protective factors included sufficient sleep, regular physical activity, non-smoking status, and adequate emotional support. A Cumulative Protective Factor Score (range, 0-4) was constructed.</p><p><strong>Results: </strong>Among 10,923 caregivers, 1,483 (13.6%) were cancer caregivers. FMD was more prevalent in cancer caregivers than non-cancer caregivers (314 [21.6%] vs 1,227 [13.0%], p < 0.001), who also reported fewer protective factors. Each individual protective factor was associated with lower odds of FMD (all p < 0.001), although these associations were attenuated among cancer caregivers for sleep, physical activity, and emotional support. Predicted probabilities of FMD declined progressively with increasing cumulative protective factor scores in both cohorts. At the highest score (4), predicted FMD was similar in cancer and non-cancer caregivers (10% vs 7%, p = 0.12). Among cancer caregivers, females exhibited higher predicted FMD than males across all cumulative protective factor levels.</p><p><strong>Conclusion: </strong>Cancer caregivers experience disproportionately high mental distress, particularly when protective resources are limited. However, the co-occurrence of multiple health-promoting behaviors and emotional support may offset this burden. Sex-based disparities persisted, underscoring the need for tailored, caregiver-centered support strategies.</p><p><strong>Implications for cancer survivors: </strong>Supporting caregivers of cancer survivors through interventions that promote healthy behaviors and emotional support may reduce mental distress and improve survivorship care outcomes.</p>","PeriodicalId":15284,"journal":{"name":"Journal of Cancer Survivorship","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148919717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Income, race, and cardiovascular disease in female breast cancer survivors: evidence of moderated socioeconomic protection in the National Health Interview Survey (NHIS) 2019-2022. 女性乳腺癌幸存者的收入、种族和心血管疾病:2019-2022年全国健康访谈调查(NHIS)中适度社会经济保护的证据
IF 3.4 2区 医学
Journal of Cancer Survivorship Pub Date : 2026-09-04 DOI: 10.1007/s11764-026-02112-3
Robina Josiah Willock, Daniel Parks, Samah Nabi, Brian Rivers, Desiree Rivers, Chaohua Li, Phillip Levy
{"title":"Income, race, and cardiovascular disease in female breast cancer survivors: evidence of moderated socioeconomic protection in the National Health Interview Survey (NHIS) 2019-2022.","authors":"Robina Josiah Willock, Daniel Parks, Samah Nabi, Brian Rivers, Desiree Rivers, Chaohua Li, Phillip Levy","doi":"10.1007/s11764-026-02112-3","DOIUrl":"https://doi.org/10.1007/s11764-026-02112-3","url":null,"abstract":"<p><p>Cardiovascular disease (CVD) remains a leading cause of poor outcomes among breast cancer survivors. Treatment contributes to both acute and long-term CVD risk, but social determinants of health (SDoH), like economic deprivation, also compound vulnerability. This study examined the associations between poverty-to-income ratio (PIR) and self-reported CVD in a national sample of breast cancer survivors.</p><p><strong>Methods: </strong>Using National Health Interview Survey (NHIS) data from 2019 to 2022, we examined sociodemographic characteristics, health behaviors, and comorbidities in a sample of 2745 female breast cancer survivors. We tested IPTW-adjusted logistic models for associations between PIR and CVD prevalence and interactions by race, age, years of survivorship, and delayed medical care.</p><p><strong>Results: </strong>Higher income did not protect survivors equally. The protection of higher PIR was significantly modified by race/ethnicity (p < 0.0001). Higher PIR reduced the odds of CVD 92% among Black survivors, compared to 68% among White survivors, with no significant association among Asian survivors. The protection of higher PIR was greatest among survivors aged < 65 years and lessened progressively up to ≥ 85 years (p = 0.017). The overall interaction terms were non-significant (p > 0.05) for years of breast cancer survivorship and approached significance for delayed care-seeking.</p><p><strong>Conclusions: </strong>PIR emerged as a robust predictor of comorbid CVD with strongest protection among younger, racial/ethnic minority, and early-survivorship subgroups.</p><p><strong>Implications for cancer survivors: </strong>Clinical CVD risk models in breast cancer remain underspecified when measures of economic status are excluded. These findings support extending clinical guidance for CVD prevention beyond the current 5-year threshold and integrating economic screening into survivorship care.</p>","PeriodicalId":15284,"journal":{"name":"Journal of Cancer Survivorship","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148891837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Illness perceptions and symptom burden in chemotherapy-induced peripheral neuropathy: a moderated mediation analysis from a self-regulatory perspective. 化疗引起的周围神经病变的疾病认知和症状负担:从自我调节的角度进行调节的中介分析。
IF 3.4 2区 医学
Journal of Cancer Survivorship Pub Date : 2026-09-04 DOI: 10.1007/s11764-026-02081-7
Qingchun Geng, Xiang Gao, Qian Zhao, Hongwen Ma, Ruoyi Xu, Jun Luo, Chulei Tang, Yanfei Jin
{"title":"Illness perceptions and symptom burden in chemotherapy-induced peripheral neuropathy: a moderated mediation analysis from a self-regulatory perspective.","authors":"Qingchun Geng, Xiang Gao, Qian Zhao, Hongwen Ma, Ruoyi Xu, Jun Luo, Chulei Tang, Yanfei Jin","doi":"10.1007/s11764-026-02081-7","DOIUrl":"https://doi.org/10.1007/s11764-026-02081-7","url":null,"abstract":"<p><strong>Purpose: </strong>Chemotherapy-induced peripheral neuropathy (CIPN) is a prevalent and often persistent adverse effect that contributes to substantial symptom burden and psychological distress among cancer survivors. However, the self-regulatory mechanisms linking patients' illness perceptions to these outcomes remain poorly understood. Guided by the Common-Sense Model of self-regulation, this study examined whether positive coping mediates the associations between illness perceptions and CIPN-related symptom burden and psychological distress, and whether mindfulness moderates these pathways.</p><p><strong>Methods: </strong>A two-center cross-sectional survey enrolled 563 adults receiving platinum-based chemotherapy who reported CIPN symptoms. Validated questionnaires assessed CIPN symptom severity, psychological distress, illness perceptions, positive coping, mindfulness, and physical activity. Structural equation modeling with bootstrapping tested mediation and moderated mediation, adjusting for covariates.</p><p><strong>Results: </strong>More threatening illness perceptions were significantly associated with greater CIPN symptom burden and higher psychological distress. Positive coping partially mediated these associations, accounting for 51% of the total association with symptom burden and 37% with psychological distress. Mindfulness moderated key pathways, indicating that the strength of associations between illness perceptions, coping, and outcomes varied according to mindfulness levels.</p><p><strong>Conclusions: </strong>These findings support a self-regulatory framework in which illness perceptions influence CIPN-related physical and psychological outcomes partly through coping processes, while mindfulness shapes vulnerability across pathways.</p><p><strong>Implications for cancer survivors: </strong>Interventions targeting illness perceptions, coping skills, and mindfulness may help cancer survivors better manage CIPN symptoms and psychological distress, thereby supporting more comprehensive survivorship care.</p>","PeriodicalId":15284,"journal":{"name":"Journal of Cancer Survivorship","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148891809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Demystifying financial toxicity measures: semi-structured interviews comparing COST-FACIT and ENRICh among cancer survivors on targeted oral anticancer medications (TOAMs). 揭开财务毒性措施的神秘面纱:半结构化访谈,比较使用靶向口服抗癌药物(TOAMs)的癌症幸存者的成本- facit和富集。
IF 3.4 2区 医学
Journal of Cancer Survivorship Pub Date : 2026-09-04 DOI: 10.1007/s11764-026-02109-y
Lisa M Lowenstein, Maria P Bernal, Erik P Bergren, Taahir K Busaidy, Eden R Brauer, Patricia A Ganz, Grace L Smith, Ya-Chen Tina Shih
{"title":"Demystifying financial toxicity measures: semi-structured interviews comparing COST-FACIT and ENRICh among cancer survivors on targeted oral anticancer medications (TOAMs).","authors":"Lisa M Lowenstein, Maria P Bernal, Erik P Bergren, Taahir K Busaidy, Eden R Brauer, Patricia A Ganz, Grace L Smith, Ya-Chen Tina Shih","doi":"10.1007/s11764-026-02109-y","DOIUrl":"10.1007/s11764-026-02109-y","url":null,"abstract":"<p><strong>Purpose: </strong>Despite increasing efforts to address financial toxicity among patients with cancer, approaches to best identify patients for targeted intervention remain unclear. We compared qualitative accounts of financial toxicity among patients receiving targeted oral anticancer medications (TOAMs) to their scores in two screening tools, the COmprehensive Score for financial Toxicity-Functional Assessment of Chronic Illness Therapy (COST-FACIT) and the Economic Strain and Resilience in Cancer (ENRICh).</p><p><strong>Methods: </strong>We conducted mixed-methods analysis of adult patients at a comprehensive cancer center. Patients had confirmed cancer diagnoses and orders for TOAMs in the last 3 months. Participants completed surveys (n = 108), and a subset with COST-FACIT scores indicating financial toxicity participated in semi-structured interviews (n = 20). We applied the Framework Method to examine qualitative accounts and developed joint matrices to assess how well each measure identified financial toxicity.</p><p><strong>Results: </strong>Qualitative accounts highlighted two elements of financial toxicity: financial strain and financial worry. For participants with extreme accounts of financial strain and financial worry (n = 6), COST-FACIT and ENRICh scores indicated medium to high levels of financial toxicity. For the rest (n = 14), qualitative accounts of financial strain and financial worry were not completely captured by COST-FACIT and/or ENRICh.</p><p><strong>Conclusion: </strong>Our findings suggest a single measure may not adequately identify financial toxicity and differentiate between strain and worry. A stepwise, wholistic approach may better identify and connect patients to appropriate resources.</p><p><strong>Implications for cancer survivors: </strong>Interventions that address financial toxicity in this group may need to use more than one measure to identify and route patients to targeted intervention.</p>","PeriodicalId":15284,"journal":{"name":"Journal of Cancer Survivorship","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13614440/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148891820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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