Journal of Bioanalysis & Biomedicine最新文献

{"title":"World Biotechnology Congress happening in Barcelona, Spain | November 18-19, 2020","authors":"E. S. D. Santos","doi":"10.37421/jbabms.2020.12.229","DOIUrl":"https://doi.org/10.37421/jbabms.2020.12.229","url":null,"abstract":"Hilaris SRL is going to host its premier World Biotechnology Congress 2020 during November 18-19, 2020, Barcelona, Spain. Biotechnology Congress aims to create a bridge between academia and industry by providing vast learning opportunities in multidisciplinary sectors and applied fields of Biotechnology. Hilaris SRL along with its World Biotechnology Congress will gather all the stakeholders of the emerging biotechnology sector and will offer the best platform to exchange knowledge and network. World Biotechnology Congress 2020 will be the premier event for Hilaris Conferences at Barcelona, which will provide a great opportunity for the stakeholders of Biotech, Pharma, and Life Sciences industry to network, establish business partnerships and will get direct access to the target audiences. Our Biotechnology 2020 Conference will provide access to key investors in the Biotechnology sectors including small & Mid Pharma, R&D companies, Innovators and key decision-makers.","PeriodicalId":15259,"journal":{"name":"Journal of Bioanalysis & Biomedicine","volume":"37 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84798873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Editorial Note on Bioanalysis & Biomedicine.","authors":"H. Shirzadfar","doi":"10.37421/jbabm.2020.12.233","DOIUrl":"https://doi.org/10.37421/jbabm.2020.12.233","url":null,"abstract":"Journal of Bioanalysis and Biomedicine (ISSN: 1948-593X) is an Open Access, quick rapid peer-reviewed journal that expects to publish the most complete and solid wellspring of data on disclosures, current developments and flow advancements which empowers creative research, covering all viewpoints in the field. Journal of Bioanalysis & Biomedicine publishes articles related to the below fields, but not limited to them: current research on Biomedicine and Pharmacotherapy, Negative results of Biomedicine, Molecular Epidomology, Nanomedicine, Drug Development, Toxicology, Biomarkers is toxicology, Spectroscopic & Chromatographic techniques etc. Editorial Board in order to ensure excellence, quintessence of the work and number of citations received for the equivalent published articles. Journal of Bioanalysis & Biomedicine is indexed in several indexing databases like Index Copernicus, Academic Keys, SafetyLit, RefSeek, Hamdard University, EBSCO A-Z, OCLC- WorldCat, Publons, Geneva Foundation for Medical Education and Research. It’s all our pleasure to announce that during the year 2019, all issues of volume 11 were published online within the time and the release issues were also brought out furthermore, dispatched inside 30 days of publishing the issue online. Beside, our journal is planning to bring an online special issue (Isolation and quarantine in covid-19). During the schedule year 2019 we received numerous papers, which experienced fundamental screening for plagiarism, in the wake of screening and peer-review process, we distributed papers in 2019. Normal time is 6 two months from qualified prominent reviewers. Our review process can be followed by the authors whenever and can contact us through online portal system. Our Journal is releasing issues with the recurrence of Bimonthly. It additionally supports to related conferences which are on-going all through the world. The journal has famous and constrained editorial board members who are significantly gainful and takes an intrigue viably in the improvement of the Journal. I accept this open door to thank my Editorial Board members and reviewers who are distinctly participating in editing of articles to publish the papers. Thanks to their generous support towards the journal. We might likewise want to thank our mass mailing group which is useful in this journey. According to the Google Analytics our Journal of Bioanalysis & Biomedicine is getting good no. of visitors to our website daily. We are glad to illuminate you that our Twitter account is having 200+ supporters in the range of a half year. We additionally have followers in linkedin and facebook social sites. We are getting acceptable number of articles in 2020, expecting to get more articles which upgrade our journal notoriety in the upcoming days. We are pleased to declare that our journal effectively finished 1 issue discharges and the other issue is prepared to release. More participation ","PeriodicalId":15259,"journal":{"name":"Journal of Bioanalysis & Biomedicine","volume":"9 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75344942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Review on LBA and LC-MS Platforms for Supporting Large Molecule Pharmacokinetics Bioanalysis","authors":"X. Zhang, Linglong Zou, Weiping Shao, Z. Lin","doi":"10.37421/1948-593X.2020.12.227","DOIUrl":"https://doi.org/10.37421/1948-593X.2020.12.227","url":null,"abstract":"Over the past ten years, the global market for large molecule therapeutics has rapidly grown for the treatment of a variety of diseases. LBA and LC-MS are two platforms widely used in pharmacokinetic bioanalysis. In this review, we compare LBA and LC-MS and summarize their strengths and limitations. Strategies for platform selection are provided according to the study purpose, study phase, analyte types, assay requirements and other factors.","PeriodicalId":15259,"journal":{"name":"Journal of Bioanalysis & Biomedicine","volume":"231 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72890366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Compatibility studies of montelukast with pharmaceutical excipients used in tablet formulations using thermal and chromatographic techniques","authors":"Radhe Shyam Sahu, D. Jain","doi":"10.37421/1948-593X.2020.12.15","DOIUrl":"https://doi.org/10.37421/1948-593X.2020.12.15","url":null,"abstract":"Differential Scanning Calorimetry (DSC) and Isothermal Stress Testing (IST) were carried out to screen compatibility of montelukast (MNLT) with some currently employed pharmaceutical excipients. Initially, DSC thermogram was used to screen MNLT-excipients compatibility. Thermal Gravimetry analysis (TGA) thermogram and Fourier Transform Infra Red (FTIR) spectrum of binary mixture of MNLT-excipients were also compared with that of pure MNLT and excipients. Isothermal stress testing was carried out by storing MNLT-excipient binary mixture (1:1 w/w) for 3 weeks under 500 C. Based on the results of DSC, IR, TGA and HPLC, commenly used excipients were found to be compatible with MNLT excluding citric acid which exhibited interaction with montelukast.","PeriodicalId":15259,"journal":{"name":"Journal of Bioanalysis & Biomedicine","volume":"60 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82946514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial Note on Liquid Chromatography - Mass Spectrometry","authors":"S. Kalayci","doi":"10.37421/1948-593X.2020.12.240","DOIUrl":"https://doi.org/10.37421/1948-593X.2020.12.240","url":null,"abstract":"Received 06 November 2020; Accepted 19 November 2020; Published 25 November 2020 Journal of Bioanalysis & Biomedicine (jbabm) recognizes its decade long service to the scientific community by reliably publishing peer-reviewed articles and tracking the progress and following the advancements in the field of Biomedicine and Pharmacotherapy, Negative results of Biomedicine, Molecular Epidomology, Nanomedicine, Drug Development, Toxicology, Biomarkers in toxicology.","PeriodicalId":15259,"journal":{"name":"Journal of Bioanalysis & Biomedicine","volume":"67 1 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84263732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Announcement on Stem cell 2020 WebinarTheme: Covid 19: Challenges Ahead for Stem cell and Regenerative Medicine","authors":"Dayal Sam","doi":"10.37421/JBABMS.2020.12.230","DOIUrl":"https://doi.org/10.37421/JBABMS.2020.12.230","url":null,"abstract":"We cordially like to invite you to join a webinar on Stem cell 2020 during October 22-23, 2020. Stem Cell 2020 Webinar serves as a tool to educate healthcare providers on best practices to improve patient safety. Share and gain your knowledge on Stem Cell and Regenerative Medicine, Stem Cell 2020 as webinar will be an excellent network where all Health Care Professional and practisers will meet. You can participate in our Webinar without leaving your work and staying at your home. Stem Cell Webinar is an engaging online event where a speaker delivers presentation to a large audience who participate for our Stem Cell 2020 Webinar. In fight against COVID 19, Stem Cell Researcher face high- stakes decisions, Moral Distress, As the number of confirmed COVID-19 cases accelerates Doctors on the front lines of the health care response have found themselves in unprecedented positions, making high-stakes decisions for patients.","PeriodicalId":15259,"journal":{"name":"Journal of Bioanalysis & Biomedicine","volume":"14 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79263740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Editorial Note on Bioanalysis & Biomedicine","authors":"eep Kumar Kar","doi":"10.37421/jbabm.2020.12.234","DOIUrl":"https://doi.org/10.37421/jbabm.2020.12.234","url":null,"abstract":"Journal of Bioanalysis & Biomedicine (ISSN: 1948-593X) Hilaris publication, is an international prominent journal focusing on studies pertaining to Pharmaceutics, Pharmacology, Pharmacotherapy, Negative results of Biomedicine, Molecular Epidomology, Nanomedicine, Drug Development, Toxicology, Biomarkers is toxicology, Spectroscopic & Chromatographic techniques etc. It is an open access and peer reviewed journal by famous Editorial Board and the manuscripts are peer-reviewed by potential reviewers as indicated by their research interest. Throughout the previous 3 years, published papers have been under the solid and able leadership of our Editor-in-Chief's Dr. Alexey Goltsov Particularly, we are grateful to for his persistent help and devotion towards the diary won't lost. We the distribution office of Journal of Bioanalysis and Biomedicine including me, we as a whole are respected and thankful for his benevolent dedication towards the journal. We provide a fast pivot time workable for peer reviewing on and publishing the article online and to scatter the articles freely for exploration, educating and reference purposes. The Journal of Bioanalysis and Biomedicine additionally fills in as an abridgment of information in pharmaco the study of disease transmission and drug safety which can be promptly gotten to by physicians, specialists, clinical researchers, general wellbeing experts, clinical understudies, clinicians, lab scientists, academicians and industry for keeping themselves refreshed and furthermore to detail further research programs. The Journal of Bioanalysis and Biomedicine consistently distributes reports covering wide scope of subjects which incorporate new difficulties of over Pharmacology, Pharmacognosy and Phytochemistry just as different parts of biomedical sciences. Applied Strategies in 2019 We have applied many strategies in 2019, i.e. • Using contacting through Mobile (Whatsapp) telephones • Sent Call for papers for the famous in the field • Approaching the Editors proposed prominent • Approaching possible reviewers for the Call for papers • Maintaining the frequency of articles. Conclusion I wish to give some point of view from the cycling research network of Journal of Bioanalysis and Biomedicine with respect to an ongoing Editorial note of our Journal. I exclusively accept that the quality of the journal depends on the Eminence nearness in the Editorial Board just as Reviewer Board (possible reviewers) who endeavor to make the","PeriodicalId":15259,"journal":{"name":"Journal of Bioanalysis & Biomedicine","volume":"30 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88030860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Brief Review on Journal of Bioanalysis and Biomedicine","authors":"W. Fischer","doi":"10.37421/JBABM.2020.12.238","DOIUrl":"https://doi.org/10.37421/JBABM.2020.12.238","url":null,"abstract":"Dear Readers, With an incredible pleasure, I would like to express my happiness not long before going into the twelfth year of this Scientific Publishing Field. Initially we started this Journal of Bioanalysis & Biomedicine (jbabm) with the aim to disperse progressed information everywhere on the globe. Fortunately, with the consistent assistance of Eminent Editorial Board Members, Potential Reviewers and Active Authors we can run this journal so adequately till now and we believe it proceeds in not so distant future moreover. Journal of Bioanalysis & Biomedicine provides the half yearly publication of articles. In the year of 2019, we have published a good number of articles, which were recent discoveries. In the earlier years, aside releasing standard issues at present, our rule community is to make scientific papers more open for aspiring scientists. With the help of Editorial board members, Executive editors and Guest Editors, we are aiming to devise interesting special issue point’s focuses to stimulate the authors. Journal of Bioanalysis & Biomedicine comes under the top ten journals in this open access field. In 2020, we have already released five issues and now we are in the process of releasing another issue. The point of convergence of the high impact factor journal offers an open access stage for clinical and lab experts, academicians and researchers keen in exploring and presenting the clinical implications of Biomedicine and Pharmacotherapy are significant regions of enthusiasm for this journal.","PeriodicalId":15259,"journal":{"name":"Journal of Bioanalysis & Biomedicine","volume":"51 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84645138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vaccine & Immunotherapy Summit October 14-15, 2020 | Brussels, Belgium","authors":"Z. Farajzadegan","doi":"10.37421/jbabm.2020.12.237","DOIUrl":"https://doi.org/10.37421/jbabm.2020.12.237","url":null,"abstract":"Exposure to reactive oxygen species can result in formation of oxidized nucleotides which increase the frequency of mutations, DNA damage, and cell death. MutT Homolog 1 (MTH1) is an enzyme that catalyzes removal of pyrophosphate from the highly mutagenic oxidized nucleoside triphosphate 8-oxo-2'-deoxyguanosine-5'-triphosphate (8-oxo-dGTP). Interest in MTH1 as a potential new target for cancer therapy surged due to reports of MTH1 inhibitors causing DNA damage and inducing cell death in cancer cells. However, questions have been raised about MTH1 target validation. One critical piece of information that is currently lacking is a quantitative understanding of the levels of 8-oxo-dGTP in cancer cells and the effect of MTH1 inhibition on them. In this study, we developed a sensitive and selective method to simultaneously measure the intracellular concentrations of 8-oxo guanosine nucleotides and their unmodified counterparts using liquid chromatography coupled to tandem mass spectrometry (LC-MS/ MS). An ion-pairing reversed phase liquid chromatography method using dimethylhexylamine was employed to quantify the highly polar analytes. The method was validated fit for purpose using a combination of authentic standards and cell samples. The intracellular oxo-nucleotide concentrations in human bone osteosarcoma cell line U2OS were determined using the method. We observed very low levels of 8-oxo nucleotides in untreated and hydrogen peroxide treated cells and MTH1 knockdown in these cells had minimal if any effect on 8-oxo nucleotide levels. This method will allow for a more comprehensive understanding of oxidized nucleotide detoxification pathways and MTH1 as a target for cancer therapy.","PeriodicalId":15259,"journal":{"name":"Journal of Bioanalysis & Biomedicine","volume":"1980 1","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89817502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Announcement of ANTIBIOTICS: DISCOVERY & DEVELOPMENT scheduled in New York, USA during October 26-27, 2021","authors":"Alice Genyi","doi":"10.37421/jbabm.2020.12.236","DOIUrl":"https://doi.org/10.37421/jbabm.2020.12.236","url":null,"abstract":"","PeriodicalId":15259,"journal":{"name":"Journal of Bioanalysis & Biomedicine","volume":"32 1 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78637914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}