{"title":"Physicians Have Extensive Education in Musculoskeletal Medicine","authors":"Loai Aljerf","doi":"10.37421/1948-593X.2021.13.270","DOIUrl":"https://doi.org/10.37421/1948-593X.2021.13.270","url":null,"abstract":"","PeriodicalId":15259,"journal":{"name":"Journal of Bioanalysis & Biomedicine","volume":"45 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85073077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Involvement of Chromatographic Techniques in Organic Compound","authors":"Krishanu Ray","doi":"10.37421/1948-593X.2021.13.264","DOIUrl":"https://doi.org/10.37421/1948-593X.2021.13.264","url":null,"abstract":"During the previous decade significant advances have occurred in computerized and simple hardware, PC frameworks and instrument plan which has enabled dedicated gas chromatography (GC) and and high performance liquid chromatography (HPLC) instruments to be planned consolidating reduced incorporated spectroscopic identifiers, especially mass spectrometric (MS) detectors. Control programming and information bases joining libraries of reference spectra run on quick (PC) workstations, this permits test blends containing basic natural analytes to be isolated and distinguished on a standard premise utilizing a solitary seat top instrument.","PeriodicalId":15259,"journal":{"name":"Journal of Bioanalysis & Biomedicine","volume":"17 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85931623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ifeanyi Peter Onyeka, O. Aziakpono, U. Morikwe, Onyebuchi Hillary Nwafor, N.M. Adione
{"title":"Physicochemical and Anti-Diabetic Effect of the Crude Leaf Extract of Mallotus oppostifollous (Euphorbiaceae) in Alloxan Induced Diabetic Mice","authors":"Ifeanyi Peter Onyeka, O. Aziakpono, U. Morikwe, Onyebuchi Hillary Nwafor, N.M. Adione","doi":"10.37421/1948-593X.2021.13.279","DOIUrl":"https://doi.org/10.37421/1948-593X.2021.13.279","url":null,"abstract":"Background: Diabetes mellitus results when there is an imbalance in the production, metabolism and regulation of insulin and blood glucose respectively, in the human body. This study investigated the fresh leaf microscopy and chemomicroscopy, phytochemical, acute toxicity and the anti-diabetic potentials of Mallotus oppostifollous using the mice diabetic model. Methods: Mallotus oppostifollous was extracted using the cold maceration method with absolute methanol. The acute toxicity (LD 50) of the fraction extract was determined in mice using Lorke’s method. The antidiabetic studies were conducted using the standard protocol of alloxan induced diabetic mice. Results: The findings showed that no toxicity was observed up to 5000 mg/kg doses of the crude extract. The phytochemical screening revealed the presence glycosides, saponins, alkaloids, flavonoids and tannins, steroids and terpenoids of the crude extract of Mallotus oppostifollous decreased blood glucose levels significantly (P<0.05) within 10 hours’ acute treatment and 14 days long term treatment. Histological examination showed a consistent rejuvenation of the pancreatic β cells islet of diabetic mice treated with methanol leaf extract Mallotus oppostifollous. The result also showed abundance of manganese, magnesium, iron, calcium, zinc and potassium which are all implicated in secretion and metabolism of insulin. Conclusion: Mallotus oppostifollous may have acted by restoring pancreatic beta-cell integrity through mopping of reactive oxygen species (ROS) associated with the diabetic state, and thereby improving pancreatic function and consequently, lowering of fasting blood glucose levels. These findings provide ample evidence to support the traditional use of Mallotus oppostifollous in the management of diabetes mellitus.","PeriodicalId":15259,"journal":{"name":"Journal of Bioanalysis & Biomedicine","volume":"8 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75962818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Editorial Note on Spectroscopy","authors":"Loai Aljerf","doi":"10.37421/1948-593X.21.13.245","DOIUrl":"https://doi.org/10.37421/1948-593X.21.13.245","url":null,"abstract":"Received 06 January 2021; Accepted 27 January 2021; Published 30 January 2021 Journal of Bioanalysis & Biomedicine (jbabm) recognizes its decade long service to the scientific community by reliably publishing peer-reviewed articles and tracking the progress and following the advancements in the field of Biomedicine and Pharmacotherapy, Negative results of Biomedicine, Molecular Epidomology, Nanomedicine, Drug Development, Toxicology, Biomarkers in toxicology.","PeriodicalId":15259,"journal":{"name":"Journal of Bioanalysis & Biomedicine","volume":"57 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84559919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Short Note on Nanomedicine in Thrombosis","authors":"R. Ghosh","doi":"10.37421/1948-593X.2021.13.282","DOIUrl":"https://doi.org/10.37421/1948-593X.2021.13.282","url":null,"abstract":"There are an expanded number of Research articles in the Journal of Bio analysis and Biomedicine and somewhere else depicting potential utilizations of Nanomedicine in cardiovascular illnesses. These infections have an expanded occurrence in developed countries because of a maturing populace and will also gradually increase in developing countries. As a general rule, the Nanomedical applications depicted in the literature have been focusing in on imaging and treatment of atherosclerosis and in vivo and ex-vivo distinguishing proof and checking of vascular bio signatures to name only two examples. Thrombosis is, not withstanding, a space of cardiovascular examination that would generously benefit of novel and supported nanotechnology approaches. This area isn't being examined and openings flourish for nanotechnologists and biomedical analysts to team up to progress Nanomedical answers for further developing analysis and getting movement and repeat of thrombosis. During thrombosis there is an arrangement of blood clusters with the vessels that lead to blood vessel or vein deterrent, aggravation, just as the creation of favorable to coagulant vesicles known as microparticles, delivered fundamentally from platelets.","PeriodicalId":15259,"journal":{"name":"Journal of Bioanalysis & Biomedicine","volume":"8 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85597812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"New Materials for Sensing and Functional Bio-Applications: Nanoparticle Systems","authors":"K. Ray","doi":"10.37421/1948-593X.2021.13.281","DOIUrl":"https://doi.org/10.37421/1948-593X.2021.13.281","url":null,"abstract":"The interface among biology and Nanomaterial's is an arising frontier for innovative work in science and technology. Currently significant research activities are centered around utilizing or emulating biological materials, including self-assembly in living and synthetic materials, bio-functionalization of Nanomaterial’s, control of cell conduct through Nano-designed materials , and hybrid systems comprising of biomolecules and inorganic materials, like Metallic Nanoparticles (MNPs) and semiconductor Quantum Dots (QDs). These frameworks, which are of interest for different applications (counting biosensors, responsive nanoparticle frameworks and so on) are generally founded on the natural resonances of QDs (excitons) and MNPs (plasmons), Forster energy transfer, and the effect of climate on biomolecules. Considerable research efforts have effectively been dedicated to considering potential uses of such frameworks for biosensors that can sensitively monitor binding events in real time and can detect a variety of processes, including self-collected monolayer arrangement, protein-ligand and antibody-protein interactions, DNA hybridization, and protein conformational changes.","PeriodicalId":15259,"journal":{"name":"Journal of Bioanalysis & Biomedicine","volume":"38 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88665446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"New Nanomedicine Block the Advancement of Pancreatic Cancer","authors":"K. Ray","doi":"10.37421/1948-593X.2021.13.288","DOIUrl":"https://doi.org/10.37421/1948-593X.2021.13.288","url":null,"abstract":"","PeriodicalId":15259,"journal":{"name":"Journal of Bioanalysis & Biomedicine","volume":"27 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88745626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Note on NMR to Improve Drug Development","authors":"Ankhita Chobe","doi":"10.37421/1948-593X.2021.13.276","DOIUrl":"https://doi.org/10.37421/1948-593X.2021.13.276","url":null,"abstract":"","PeriodicalId":15259,"journal":{"name":"Journal of Bioanalysis & Biomedicine","volume":"55 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91081586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Development of 3D-Printed Jelly for Biomedical Materials","authors":"Ankhita Chobe","doi":"10.37421/1948-593X.2021.13.278","DOIUrl":"https://doi.org/10.37421/1948-593X.2021.13.278","url":null,"abstract":"Received 16 July 2021; Accepted 23 July 2021; Published 30 July 2021 3D-printable gels with improved and extremely controlled properties are often created by merging microand Nano-sized networks of identical materials controlled from algae, in line with new analysis from North geographical area State University. The findings might have applications in medical specialty materials -think about biological scaffolds for growing cells-and soft artificial intelligence.","PeriodicalId":15259,"journal":{"name":"Journal of Bioanalysis & Biomedicine","volume":"1 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90108916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}