New Materials for Sensing and Functional Bio-Applications: Nanoparticle Systems

K. Ray
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Abstract

The interface among biology and Nanomaterial's is an arising frontier for innovative work in science and technology. Currently significant research activities are centered around utilizing or emulating biological materials, including self-assembly in living and synthetic materials, bio-functionalization of Nanomaterial’s, control of cell conduct through Nano-designed materials , and hybrid systems comprising of biomolecules and inorganic materials, like Metallic Nanoparticles (MNPs) and semiconductor Quantum Dots (QDs). These frameworks, which are of interest for different applications (counting biosensors, responsive nanoparticle frameworks and so on) are generally founded on the natural resonances of QDs (excitons) and MNPs (plasmons), Forster energy transfer, and the effect of climate on biomolecules. Considerable research efforts have effectively been dedicated to considering potential uses of such frameworks for biosensors that can sensitively monitor binding events in real time and can detect a variety of processes, including self-collected monolayer arrangement, protein-ligand and antibody-protein interactions, DNA hybridization, and protein conformational changes.
传感和功能生物应用的新材料:纳米颗粒系统
生物学和纳米材料之间的界面是科学技术创新工作的新兴前沿。目前重要的研究活动集中在利用或模拟生物材料,包括生物和合成材料的自组装,纳米材料的生物功能化,通过纳米设计材料控制细胞行为,以及由生物分子和无机材料组成的混合系统,如金属纳米颗粒(MNPs)和半导体量子点(QDs)。这些框架对不同的应用(计数生物传感器,响应纳米粒子框架等)感兴趣,通常建立在QDs(激子)和MNPs(等离子体激元)的自然共振,福斯特能量转移和气候对生物分子的影响之上。大量的研究工作已经有效地致力于考虑这些生物传感器框架的潜在用途,这些框架可以实时灵敏地监测结合事件,并可以检测各种过程,包括自收集的单层排列,蛋白质-配体和抗体-蛋白质相互作用,DNA杂交和蛋白质构象变化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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