Yetkin Korkmaz, Tufan Çınar, Faysal Şaylık, Tayyar Akbulut, Murat Selçuk, Mustafa Oğuz, Mert Ilker Hayıroğlu, İbrahim Halil Tanboğa
{"title":"Evaluation of pulmonary arterial stiffness in post mild COVID-19 patients: a pilot prospective study.","authors":"Yetkin Korkmaz, Tufan Çınar, Faysal Şaylık, Tayyar Akbulut, Murat Selçuk, Mustafa Oğuz, Mert Ilker Hayıroğlu, İbrahim Halil Tanboğa","doi":"10.1186/s44348-024-00032-3","DOIUrl":"https://doi.org/10.1186/s44348-024-00032-3","url":null,"abstract":"<p><strong>Background: </strong>Our primary goal was to utilize pulmonary arterial stiffness (PAS) to demonstrate the early alterations in the pulmonary vascular area in individuals with prior COVID-19 illness who had not undergone hospitalization.</p><p><strong>Methods: </strong>In total, 201 patients with prior COVID-19 infection without hospitalization and 195 healthy, age- and sex-matched individuals without a history of COVID-19 disease were included in this prospective analysis. The PAS value for each patient was calculated by dividing the mean peak pulmonary flow velocity by the pulmonary flow acceleration time.</p><p><strong>Results: </strong>The measured PAS was 10.2 ± 4.11 Hz/msec in post-COVID-19 participants and 8.56 ± 1.47 Hz/msec in healthy subjects (P < 0.001). Moreover, pulmonary artery acceleration time was significantly lower in patients with a prior history of COVID-19. Multivariable logistic regression analysis revealed that PAS was significantly connected to a prior COVID-19 illness (odds ratio, 1.267; 95% confidence interval, 1.142-1.434; P < 0.001). The optimal cutoff point for detecting a prior COVID-19 disease for PAS was 10.1 (sensitivity, 70.2%; specificity, 87.7%).</p><p><strong>Conclusions: </strong>This might be the first investigation to reveal that patients with a history of COVID-19 had higher PAS values compared to those without COVID-19. The results of the investigation may indicate the need of regular follow up of COVID-19 patients for the development of pulmonary arterial hypertension, especially during the post-COVID-19 interval.</p>","PeriodicalId":15229,"journal":{"name":"Journal of Cardiovascular Imaging","volume":"32 1","pages":"25"},"PeriodicalIF":0.0,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11351102/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142093210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Suyon Chang, Hoon Seok Kim, Mi-Hyang Jung, Myungshin Kim, Jong-Chan Youn
{"title":"Delayed onset of hypertrophic cardiomyopathy in a 61-year-old male patient with MYBPC3 mutation.","authors":"Suyon Chang, Hoon Seok Kim, Mi-Hyang Jung, Myungshin Kim, Jong-Chan Youn","doi":"10.1186/s44348-024-00009-2","DOIUrl":"10.1186/s44348-024-00009-2","url":null,"abstract":"","PeriodicalId":15229,"journal":{"name":"Journal of Cardiovascular Imaging","volume":"32 1","pages":"24"},"PeriodicalIF":0.0,"publicationDate":"2024-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11321234/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141971195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Echocardiographic estimation of pulmonary arterial and right atrial pressures in children with congenital heart disease: a comprehensive prospective study and introduction of novel equations.","authors":"Elaheh Malakan Rad, Reza Elhamian, Keyhan Sayadpour Zanjani, Reza Shabanian, Ehsan Aghaei Moghadam, Mohamad Taghi Majnoon, Aliakbar Zeinaloo","doi":"10.1186/s44348-024-00023-4","DOIUrl":"10.1186/s44348-024-00023-4","url":null,"abstract":"<p><strong>Background: </strong>Pediatric pulmonary hypertension (PH) is characterized by a mean pulmonary arterial pressure exceeding 20 mmHg. There is limited research on the suitability of adult-based methods for estimating PH in pediatric populations. Using established formulas for adults, this study aimed to evaluate the correlation between echocardiographic estimates of systolic, diastolic, and mean pulmonary arterial pressures, and mean right atrial pressures in children with congenital heart disease (CHD).</p><p><strong>Methods: </strong>A prospective study was conducted involving children with CHD undergoing cardiac catheterization without prior cardiac surgery. We used echocardiography to estimate pulmonary and right atrial pressures and compared these with invasively measured values. Four reliable regression equations were developed to estimate systolic, diastolic, and mean pulmonary arterial pressures, and mean right atrial pressures. Cutoff values were determined to predict the occurrence of PH. Linear regression, Bland-Altman analysis, and receiver operating characteristic curve analysis were performed to assess the accuracy of echocardiography and establish diagnostic thresholds for PH.</p><p><strong>Results: </strong>The study involved 55 children (23 with normal pulmonary arterial pressure and 32 with PH) with acyanotic CHD aged 1 to 192 months. Four equations were developed to detect high pulmonary arterial pressures, with cutoff values of 32.9 for systolic pulmonary arterial pressure, 14.95 for diastolic pulmonary arterial pressure, and 20.7 for mean pulmonary arterial pressure. The results showed high sensitivity and moderate specificity but a tendency to underestimate systolic and mean pulmonary arterial pressures at higher pressures.</p><p><strong>Conclusions: </strong>The study provides valuable insights into the use of adult-based echocardiographic formulas for estimating PH in pediatric patients with acyanotic CHD.</p>","PeriodicalId":15229,"journal":{"name":"Journal of Cardiovascular Imaging","volume":"32 1","pages":"23"},"PeriodicalIF":0.0,"publicationDate":"2024-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11308456/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141901899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Inki Moon, Soongu Kwak, MinKwan Kim, Seung-Pyo Lee, Hyung-Kwan Kim, Yong-Jin Kim, Jun-Bean Park
{"title":"Assessment of right ventricular systolic function using speckle tracking strain imaging in patients with severe tricuspid regurgitation: a validation study with cardiac magnetic resonance.","authors":"Inki Moon, Soongu Kwak, MinKwan Kim, Seung-Pyo Lee, Hyung-Kwan Kim, Yong-Jin Kim, Jun-Bean Park","doi":"10.1186/s44348-024-00015-4","DOIUrl":"10.1186/s44348-024-00015-4","url":null,"abstract":"<p><strong>Background: </strong>Right ventricular (RV) systolic dysfunction is an established prognostic factor in patients with severe tricuspid regurgitation (TR). However, accurate assessment of RV systolic function using conventional echocardiography remains challenging. We investigated the accuracy of strain measurement using speckle tracking echocardiography (STE) for evaluating RV systolic function in patients with severe TR.</p><p><strong>Methods: </strong>We included consecutive patients with severe TR who underwent echocardiography and cardiac magnetic resonance imaging (CMR) within 30 days between 2011 and 2023. Two-dimensional STE was used to measure RV free wall longitudinal strain (RVFWLS) and global longitudinal strain (RVGLS). These values were compared with the RV ejection fraction (RVEF) from CMR. RV systolic dysfunction was defined as a CMR-derived RVEF < 35%.</p><p><strong>Results: </strong>A total of 87 patients with severe TR were identified during the study period. Among echocardiographic RV strain measurements, RVFWLS was the best correlate of CMR-derived RVEF (r = -0.37, P < 0.001), followed by RVGLS (r = -0.27, P = 0.012). Receiver operating characteristic (ROC) curve analysis revealed that RVFWLS provided better discrimination of RV systolic dysfunction, yielding an area under the ROC curve (AUC) of 0.770 (95% confidence interval [CI], 0.696-0.800) than RV fractional area change (AUC, 0.615; 95% CI, 0.500-0.859).</p><p><strong>Conclusions: </strong>In patients with severe TR, STE-derived RVFWLS showed the best correlation with RVEF on CMR and displayed superior discrimination of RV systolic dysfunction compared with the RV fractional area change. This study suggests the potential usefulness of STE in assessing RV systolic function in this population.</p>","PeriodicalId":15229,"journal":{"name":"Journal of Cardiovascular Imaging","volume":"32 1","pages":"22"},"PeriodicalIF":0.0,"publicationDate":"2024-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11304584/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141901898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Joana Laranjeira Correia, Gonçalo R M Ferreira, João Gouveia Fiuza, Mariana Duarte Almeida, Joana Coelho, Emanuel Correia, José Miguel Correia, Davide Moreira, Nuno Craveiro, Maria Luísa Gonçalves, Vanda Devesa Neto
{"title":"Left ventricular thrombus routine screening with contrast echocardiography in patients with anterior ST-elevation myocardial infarction: is it worth it?","authors":"Joana Laranjeira Correia, Gonçalo R M Ferreira, João Gouveia Fiuza, Mariana Duarte Almeida, Joana Coelho, Emanuel Correia, José Miguel Correia, Davide Moreira, Nuno Craveiro, Maria Luísa Gonçalves, Vanda Devesa Neto","doi":"10.1186/s44348-024-00027-0","DOIUrl":"10.1186/s44348-024-00027-0","url":null,"abstract":"<p><strong>Background: </strong>Left ventricular (LV) thrombus has a higher incidence among patients with anterior ST-elevation myocardial infarction (STEMI) when compared to other types of acute myocardial infarction and is associated with worse prognosis. The management of LV thrombus diagnosis remains challenging. Contrast echocardiography (transthoracic echocardiography, TTE) has shown potential in improving the accuracy for its diagnosis, thereby influencing treatment strategies concerning antithrombotic/anticoagulation therapy. The aim of this study was to assess the effectiveness of contrast TTE as a routine screening method for detecting LV thrombus in the acute phase of anterior STEMI.</p><p><strong>Methods: </strong>A prospective, single center, randomized controlled trial was conducted among patients with anterior STEMI. The study group underwent contrast TTE, while the control group received a conventional approach. Demographical, clinical, and diagnostic data were collected. Thrombus detection rates were compared between groups.</p><p><strong>Results: </strong>A total of 68 patients were included (32 in the study group and 36 in the control group). No substantial baseline differences were observed between groups. Thrombus detection rate was 25.0% in the study group and 13.9% in the control group, however these results did not reach statistical significance (P = 0.24). The prevalence of anterior/apical aneurysm was higher in the study group (46.9% vs. 22.2%, P = 0.03).</p><p><strong>Conclusions: </strong>Conventional TTE may be adequate for diagnosing LV thrombus in the acute phase of anterior STEMI; however, further larger-scale and multicenter studies are necessary to obtain more robust and conclusive results. Ultrasound contrast may play a significant role in the detection of anterior/apical aneurysms, which are known risk factors for the subsequent development of thrombus.</p><p><strong>Trial registration: </strong>NCT06480929 (ClinicalTrials.gov, Retrospectively registered).</p>","PeriodicalId":15229,"journal":{"name":"Journal of Cardiovascular Imaging","volume":"32 1","pages":"21"},"PeriodicalIF":0.0,"publicationDate":"2024-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11299253/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141893424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prevalence and characteristics of patients with incidental cardiac uptake on bone scintigraphy.","authors":"Jihee Son, Yeon-Hee Han, Sun Hwa Lee","doi":"10.1186/s44348-024-00030-5","DOIUrl":"10.1186/s44348-024-00030-5","url":null,"abstract":"<p><strong>Background: </strong>Bone scintigraphy is emerging as a confirmatory diagnostic tool for transthyretin cardiac amyloidosis (ATTR-CA). This study aimed to investigate the frequency and clinical characteristics of patients with incidental cardiac uptake and incidental ATTR-CA on bone scintigraphy.</p><p><strong>Methods: </strong>All bone scintigraphic studies performed at a tertiary teaching hospital between 2011 and 2022 were reviewed retrospectively. Patients who underwent bone scintigraphy to confirm ATTR-CA were excluded. Patients with cardiac uptake of grade 2 or 3 were included and divided into two groups: possible ATTR-CA group and noncardiac amyloidosis (non-CA) group.</p><p><strong>Results: </strong>Of the 61,432 bone scintigraphic studies performed on 32,245 patients, 23 (0.07%) had grade 2 or 3 cardiac uptake. Nine of 23 patients (39.1%) were assigned to the non-CA group because they showed cardiac uptake from definite other causes or focal uptake that did not match CA. The remaining 14 patients (60.9%) were classified as the possible ATTR-CA group, and five patients were referred to cardiologists and finally diagnosed with ATTR-CA. Two patients were treated with tafamidis. Patients in the ATTR-CA group were significantly older and had a less frequent history of end-stage renal disease than those in the non-CA group. Other characteristics were comparable in both groups.</p><p><strong>Conclusions: </strong>Although incidental ATTR-CA in patients undergoing bone scintigraphy for noncardiac reasons is uncommon, if cardiac uptake is observed in elderly patients without metastatic calcification associated with end-stage renal disease, further diagnostic work-up for ATTR-CA as a cause of undiagnosed heart failure should be considered.</p>","PeriodicalId":15229,"journal":{"name":"Journal of Cardiovascular Imaging","volume":"32 1","pages":"19"},"PeriodicalIF":0.0,"publicationDate":"2024-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11297744/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141878767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nihal M Batouty, Ahmad M Tawfik, Donia M Sobh, Basma N Gadelhak, Shimaa El-Ashwah, Mohamed Abdelghafar Hussein, Mai Gad, A Ashraf Abd El Aziz, Mahmoud Abd El-Shahed, Rasha Karam
{"title":"Global and regional cardiac magnetic resonance feature tracking left ventricular strain analysis in assessing early myocardial disease in β thalassemia major patients.","authors":"Nihal M Batouty, Ahmad M Tawfik, Donia M Sobh, Basma N Gadelhak, Shimaa El-Ashwah, Mohamed Abdelghafar Hussein, Mai Gad, A Ashraf Abd El Aziz, Mahmoud Abd El-Shahed, Rasha Karam","doi":"10.1186/s44348-024-00026-1","DOIUrl":"10.1186/s44348-024-00026-1","url":null,"abstract":"<p><strong>Background: </strong>Cardiac magnetic resonance imaging (CMR) is the modality of choice for quantification of myocardial iron overload in β-thalassemia major patients using the T2* sequence. CMR feature tracking (FT) is a recent magnetic resonance imaging tool that gives an idea about myocardial fibers deformation; thus, it can detect early impairment in myocardial function even before the reduction in ejection fraction.</p><p><strong>Methods: </strong>This study aims to assess the ability of left ventricular CMR-FT in the early detection of systolic dysfunction in β thalassemia major patients and to correlate it with the degree of myocardial iron overload measured by CMR T2*. This prospective study enrolled 57 β thalassemia major patients who received long-term blood transfusion and 20 healthy controls. CMR was used to evaluate left ventricular volumes, ejection fraction, and the amount of myocardial T2*. A two-dimensional left ventricular FT analysis was performed. Both global and segmental left ventricular strain values were obtained.</p><p><strong>Results: </strong>The mean global circumferential strain (GCS) and global radial strain (GRS) values were significantly lower in patients compared to control (P = 0.002 and P = 0.006, respectively). No correlation was found between T2* values and ejection fraction; however, there was a significant correlation between T2* values and GCS and GRS (P = 0.012 and P = 0.025, respectively) in thalassemia patients. Regional strain revealed significantly lower values of GCS and GRS in basal regions compared to apical ones (P = 0.000).</p><p><strong>Conclusions: </strong>Our study revealed that CMR-FT can play a role in the early detection of systolic impairment in thalassemia patients.</p>","PeriodicalId":15229,"journal":{"name":"Journal of Cardiovascular Imaging","volume":"32 1","pages":"18"},"PeriodicalIF":0.0,"publicationDate":"2024-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11297698/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141878766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Soongu Kwak, Sojung Lim, Yong-Jin Kim, Hyung-Kwan Kim
{"title":"Isolated severe mitral stenosis as an uncommon manifestation of cardiac amyloidosis.","authors":"Soongu Kwak, Sojung Lim, Yong-Jin Kim, Hyung-Kwan Kim","doi":"10.1186/s44348-024-00013-6","DOIUrl":"10.1186/s44348-024-00013-6","url":null,"abstract":"","PeriodicalId":15229,"journal":{"name":"Journal of Cardiovascular Imaging","volume":"32 1","pages":"17"},"PeriodicalIF":0.0,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11295530/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141874885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Old problem surfaces with new technology: Twiddler's syndrome in Barostim NEO.","authors":"Anila Rao, Lakshmi Rao, Akarsh Parekh, Surya Rao","doi":"10.1186/s44348-024-00010-9","DOIUrl":"10.1186/s44348-024-00010-9","url":null,"abstract":"","PeriodicalId":15229,"journal":{"name":"Journal of Cardiovascular Imaging","volume":"32 1","pages":"16"},"PeriodicalIF":0.0,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11295297/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141874886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}