Journal of Cardiovascular Translational Research最新文献_第9页

Changes in Cardiac Electrical Biomarker in Response to Coronary Arterial Occlusion: An Experimental Observation. 冠状动脉闭塞时心脏电生物标志物的变化：实验观察

IF 4.6 3区医学

Journal of Cardiovascular Translational Research Pub Date : 2024-08-01 Epub Date: 2024-02-13 DOI: 10.1007/s12265-024-10487-w

Sudipta Chattopadhyay, Felicia Adjei, Attila Kardos

{"title":"Changes in Cardiac Electrical Biomarker in Response to Coronary Arterial Occlusion: An Experimental Observation.","authors":"Sudipta Chattopadhyay, Felicia Adjei, Attila Kardos","doi":"10.1007/s12265-024-10487-w","DOIUrl":"10.1007/s12265-024-10487-w","url":null,"abstract":"Cardiac electrical biomarker (CEB), an indicator of ischaemia-induced change in myocyte polarity, has been proposed for diagnosis of acute coronary syndrome. However, effect of coronary occlusion on CEB has not been demonstrated. CEB was acquired before (CEB0), during maximal adenosine hyperaemia (CEBhyp), balloon inflations (CEBmax) and 1 (CEB1h), 2 (CEB2h) and 3 (CEB3h) h after percutaneous coronary intervention along with pre- and post-procedural troponin-I. CEB of subjects with non-cardiac chest pain without risk factors was used as controls (CEBc). \"Late recovery\" (LR) of CEB was defined as CEB3h > median-CEB0. CEB was recorded in 75 patients undergoing stenting (group 1) including 8 with FFR < 0.8 (group 1a), 25 with FFR ≥ 0.8 (group 2) and 49 controls. In group 1, CEB0 (median, IQR) was higher than CEBc (48.0; 29.5-88.3 vs 30.0; 17.0-44.0; p < 0.001). CEBmax (185; 105.0-331.0) was higher than CEB0 (p < 0.0001). CEB1h (78.0; 31.5-143.8; p < 0.0001) and CEB2h (63.0; 31.5-114.3; p = 0.039) were higher than CEB0 while CEB3h (54.0; 24.3-94.8, p = 0.152) was similar. LR occurred in 50.7% patients. CEBmax predicted LR (OR 1.01, 95% CI 1.00-1.01, p < 0.001) (AUC 0.759, p < 0.001). CEB0 in group 1a and group 2 were similar (p = 0.524). CEBhyp was higher than CEB0 in group 1a (126.0, 109.5-266.0 vs 47.5, 20.5-73.5; p = 0.016) and group 2 (44.0, 27.8-104.8 vs 39.0, 24.0-90.3; p = 0.014). CEBhyp was higher in group 1a than 2 (p = 0.039). CEBhyp (AUC 0.75, p = 0.017) accurately predicted FFR < 0.8. Coronary arterial occlusion increases CEB that retains a \"memory\" of the ischaemic event. CEBhyp was higher only when FFR was ischaemic and accurately identified FFR < 0.8.","PeriodicalId":15224,"journal":{"name":"Journal of Cardiovascular Translational Research","volume":" ","pages":"870-878"},"PeriodicalIF":4.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139722801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

PPARγ Agonist Rosiglitazone and Antagonist GW9662: Antihypertensive Effects on Chronic Intermittent Hypoxia-Induced Hypertension in Rats. PPARγ 激动剂罗格列酮和拮抗剂 GW9662：对慢性间歇性缺氧诱导的高血压大鼠的降压作用。

IF 4.6 3区医学

Journal of Cardiovascular Translational Research Pub Date : 2024-08-01 Epub Date: 2024-02-27 DOI: 10.1007/s12265-024-10499-6

Ningzhi Zhang, Feng Wei, Sisi Ning, Jialu Hu, Hongtao Shi, Zhifeng Yao, Minna Tang, Yongqiao Zhang, Jiaxin Gong, Junbo Ge, Zhaoqiang Cui

{"title":"PPARγ Agonist Rosiglitazone and Antagonist GW9662: Antihypertensive Effects on Chronic Intermittent Hypoxia-Induced Hypertension in Rats.","authors":"Ningzhi Zhang, Feng Wei, Sisi Ning, Jialu Hu, Hongtao Shi, Zhifeng Yao, Minna Tang, Yongqiao Zhang, Jiaxin Gong, Junbo Ge, Zhaoqiang Cui","doi":"10.1007/s12265-024-10499-6","DOIUrl":"10.1007/s12265-024-10499-6","url":null,"abstract":"The increased incidence of hypertension associated with obstructive sleep apnea (OSA) presents significant physical, psychological, and economic challenges. Peroxisome proliferator-activated receptor gamma (PPARγ) plays a role in both OSA and hypertension, yet the therapeutic potential of PPARγ agonists and antagonists for OSA-related hypertension remains unexplored. Therefore, we constructed a chronic intermittent hypoxia (CIH)-induced hypertension rat model that mimics the pathogenesis of OSA-related hypertension in humans. The model involved administering PPARγ agonist rosiglitazone (RSG), PPARγ antagonist GW9662, or normal saline, followed by regular monitoring of blood pressure and thoracic aorta analysis using staining and electron microscopy. Intriguingly, our results indicated that both RSG and GW9662 appeared to potently counteract CIH-induced hypertension. In silico study suggested that GW9662's antihypertensive effect might mediated through angiotensin II receptor type 1 (AGTR1). Our findings provide insights into the mechanisms of OSA-related hypertension and propose novel therapeutic targets.","PeriodicalId":15224,"journal":{"name":"Journal of Cardiovascular Translational Research","volume":" ","pages":"803-815"},"PeriodicalIF":4.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139972029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dysregulation of micro-RNA 143-3p as a Biomarker of Carotid Atherosclerosis and the Associated Immune Reactions During Disease Progression. 微小核糖核酸 143-3p 的失调是颈动脉粥样硬化的生物标志物，也是疾病进展过程中的相关免疫反应。

IF 4.6 3区医学

Journal of Cardiovascular Translational Research Pub Date : 2024-08-01 Epub Date: 2024-01-25 DOI: 10.1007/s12265-024-10482-1

Paula González-López, Yinda Yu, Shiying Lin, Óscar Escribano, Almudena Gómez-Hernández, Anton Gisterå

{"title":"Dysregulation of micro-RNA 143-3p as a Biomarker of Carotid Atherosclerosis and the Associated Immune Reactions During Disease Progression.","authors":"Paula González-López, Yinda Yu, Shiying Lin, Óscar Escribano, Almudena Gómez-Hernández, Anton Gisterå","doi":"10.1007/s12265-024-10482-1","DOIUrl":"10.1007/s12265-024-10482-1","url":null,"abstract":"Atherosclerosis commonly remains undiagnosed until disease manifestations occur. The disease is associated with dysregulated micro(mi)RNAs, but how this is linked to atherosclerosis-related immune reactions is largely unknown. A mouse model of carotid atherosclerosis, human APOB100-transgenic Ldlr-/- (HuBL), was used to study the spatiotemporal dysregulation of a set of miRNAs. Middle-aged HuBL mice with established atherosclerosis had decreased levels of miR-143-3p in their carotid arteries. In young HuBL mice, early atherosclerosis was observed in the carotid bifurcation, which had lower levels of miR-15a-5p, miR-143-3p, and miR-199a-3p, and higher levels of miR-155-5p. The dysregulation of these miRNAs was reflected by specific immune responses during atheroprogression. Finally, levels of miR-143-3p were 70.6% lower in extracellular vesicles isolated from the plasma of patients with carotid stenosis compared to healthy controls. Since miR-143-3p levels progressively decrease when transitioning between early and late experimental carotid atherosclerosis, we propose it as a biomarker for atherosclerosis.","PeriodicalId":15224,"journal":{"name":"Journal of Cardiovascular Translational Research","volume":" ","pages":"768-778"},"PeriodicalIF":4.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11371874/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139546409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction: MicroRNA-208a: a Good Diagnostic Marker and a Predictor of no-Reflow in STEMI Patients Undergoing Primary Percutaneuos Coronary Intervention. 更正：MicroRNA-208a：接受初级经皮冠状动脉介入治疗的 STEMI 患者无再流的良好诊断标志物和预测因子。

IF 2.4 3区医学

Journal of Cardiovascular Translational Research Pub Date : 2024-08-01 DOI: 10.1007/s12265-024-10486-x

Aboubakr Mohamed Salama, Wael Ali Khalil, Manar Al-Zaky, Somia Hassan Abdallah, Nader Talaat Kandil, Ahmed Abdelsabour, Ahmed Mohammed Shaker, Mesbah Taha Hasanein, Giovanni Battista Luciani, Hassan M E Azzazy

引用次数: 0

Exploration of the Potential Biomarker FNDC5 for Discriminating Heart Failure in Patients with Coronary Atherosclerosis. 探索用于鉴别冠状动脉粥样硬化患者心力衰竭的潜在生物标记物 FNDC5

IF 4.6 3区医学

Journal of Cardiovascular Translational Research Pub Date : 2024-08-01 Epub Date: 2024-02-20 DOI: 10.1007/s12265-024-10489-8

Hongchao Zheng, Yuntao Zheng, Wei Huang, Lingling Jiang, Siyu Liu, Peizhi Miao, Ning Zhu, Richard Y Cao

{"title":"Exploration of the Potential Biomarker FNDC5 for Discriminating Heart Failure in Patients with Coronary Atherosclerosis.","authors":"Hongchao Zheng, Yuntao Zheng, Wei Huang, Lingling Jiang, Siyu Liu, Peizhi Miao, Ning Zhu, Richard Y Cao","doi":"10.1007/s12265-024-10489-8","DOIUrl":"10.1007/s12265-024-10489-8","url":null,"abstract":"Coronary atherosclerosis leading to ischemic artery disease is one of the etiological factors to develop heart failure (HF). This study aimed to investigate potential biomarkers for discriminating HF in atherosclerotic patients. This study included 40 consecutive atherosclerotic patients who underwent angiography. Concentrations of B-type natriuretic peptide (BNP), fibronectin type III domain containing 5 (FNDC5), and Phosphodiesterase 9A (PDE9A) were measured in 20 atherosclerotic patients with HF symptoms/signs and 20 without HF symptoms/signs. Circulating BNP levels were elevated, while FNDC5 levels were reduced in atherosclerotic patients with HF symptoms/signs compared to those without HF symptoms/signs. Pearson correlation analysis showed a significant correlation between FNDC5 and BNP. Receiver Operating Characteristics analysis indicated that both FNDC5 and BNP were able to discriminate HF in atherosclerotic patients. Our findings suggest that FNDC5, along with BNP, has independent value as a biomarker for discriminating HF in patients with coronary atherosclerosis.","PeriodicalId":15224,"journal":{"name":"Journal of Cardiovascular Translational Research","volume":" ","pages":"795-802"},"PeriodicalIF":4.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139905718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transplantation of Human Embryonic Stem Cell-Derived Pericyte-Like Cells Transduced with Basic Fibroblast Growth Factor Promotes Angiogenic Recovery in Mice with Severe Chronic Hindlimb Ischemia. 移植经碱性成纤维细胞生长因子转导的人胚胎干细胞衍生的类周细胞可促进严重慢性后肢缺血小鼠的血管生成恢复。

IF 4.6 3区医学

Journal of Cardiovascular Translational Research Pub Date : 2024-08-01 Epub Date: 2024-02-20 DOI: 10.1007/s12265-024-10496-9

Kenichiro Shimatani, Hiromu Sato, Kazuhiko Mizukami, Atsuhiro Saito, Masao Sasai, Jun-Ichiro Enmi, Kenichi Watanabe, Masazumi Kamohara, Yoshichika Yoshioka, Shigeru Miyagawa, Yoshiki Sawa

{"title":"Transplantation of Human Embryonic Stem Cell-Derived Pericyte-Like Cells Transduced with Basic Fibroblast Growth Factor Promotes Angiogenic Recovery in Mice with Severe Chronic Hindlimb Ischemia.","authors":"Kenichiro Shimatani, Hiromu Sato, Kazuhiko Mizukami, Atsuhiro Saito, Masao Sasai, Jun-Ichiro Enmi, Kenichi Watanabe, Masazumi Kamohara, Yoshichika Yoshioka, Shigeru Miyagawa, Yoshiki Sawa","doi":"10.1007/s12265-024-10496-9","DOIUrl":"10.1007/s12265-024-10496-9","url":null,"abstract":"Critical limb ischemia (CLI) is a state of severe peripheral artery disease, with no effective treatment. Cell therapy has been investigated as a therapeutic tool for CLI, and pericytes are promising therapeutic candidates based on their angiogenic properties. We firstly generated highly proliferative and immunosuppressive pericyte-like cells from embryonic stem (ES) cells. In order to enhance the angiogenic potential, we transduced the basic fibroblast growth factor (bFGF) gene into the pericyte-like cells and found a significant enhancement of angiogenesis in a Matrigel plug assay. Furthermore, we evaluated the bFGF-expressing pericyte-like cells in the previously established chronic hindlimb ischemia model in which bone marrow-derived MSCs were not effective. As a result, bFGF-expressing pericyte-like cells significantly improved blood flow in both laser Doppler perfusion imaging (LDPI) and dynamic contrast-enhanced MRI (DCE-MRI). These findings suggest that bFGF-expressing pericyte-like cells differentiated from ES cells may be a therapeutic candidate for CLI.","PeriodicalId":15224,"journal":{"name":"Journal of Cardiovascular Translational Research","volume":" ","pages":"828-841"},"PeriodicalIF":4.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139905720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Circulating Proteome Analysis Identifies Reduced Inflammation After Initiation of Hemodynamic Support with Either Veno-Arterial Extracorporeal Membrane Oxygenation or Impella in Patients with Cardiogenic Shock. 循环蛋白质组分析发现心源性休克患者使用静脉-动脉体外膜氧合或Impella启动血流动力学支持后炎症减少

IF 4.6 3区医学

Journal of Cardiovascular Translational Research Pub Date : 2024-08-01 Epub Date: 2024-02-26 DOI: 10.1007/s12265-024-10501-1

Nikolaos A Diakos, Lija Swain, Shreyas Bhave, Xiaoying Qiao, Towia Libermann, Jillian Haywood, Siya Goel, Shiva Annamalai, Michele Esposito, Haval Chweich, Anthony Faugno, Navin K Kapur

{"title":"Circulating Proteome Analysis Identifies Reduced Inflammation After Initiation of Hemodynamic Support with Either Veno-Arterial Extracorporeal Membrane Oxygenation or Impella in Patients with Cardiogenic Shock.","authors":"Nikolaos A Diakos, Lija Swain, Shreyas Bhave, Xiaoying Qiao, Towia Libermann, Jillian Haywood, Siya Goel, Shiva Annamalai, Michele Esposito, Haval Chweich, Anthony Faugno, Navin K Kapur","doi":"10.1007/s12265-024-10501-1","DOIUrl":"10.1007/s12265-024-10501-1","url":null,"abstract":"In-hospital mortality associated with cardiogenic shock (CS) remains high despite the use of percutaneous assist devices. We sought to determine whether support with VA-ECMO or Impella in patients with CS alters specific components of the plasma proteome. Plasma samples were collected before device implantation and 72 h after initiation of support in 11 CS patients receiving ECMO or Impella. SOMAscan was used to detect 1305 circulating proteins. Sixty-seven proteins were changed after ECMO (18 upregulated and 49 downregulated, p < 0.05), 38 after Impella (10 upregulated and 28 downregulated, p < 0.05), and only eight proteins were commonly affected. Despite minimal protein overlap, both devices were associated with markers of reduced inflammation and increased apoptosis of inflammatory cells. In summary, ECMO and Impella are associated with reduced expression of inflammatory markers and increased markers of inflammatory cell death. These circulating proteins may serve as novel targets of therapy or biomarkers to tailor AMCS use.","PeriodicalId":15224,"journal":{"name":"Journal of Cardiovascular Translational Research","volume":" ","pages":"935-945"},"PeriodicalIF":4.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139972027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Modulating the Expression of Exercise-induced lncRNAs: Implications for Cardiovascular Disease Progression. 调节运动诱导的 lncRNAs 的表达：对心血管疾病进展的影响

IF 3.4 3区医学

Journal of Cardiovascular Translational Research Pub Date : 2024-06-10 DOI: 10.1007/s12265-024-10530-w

Li-Hua Yu, Ge-Lin Zhang

{"title":"Modulating the Expression of Exercise-induced lncRNAs: Implications for Cardiovascular Disease Progression.","authors":"Li-Hua Yu, Ge-Lin Zhang","doi":"10.1007/s12265-024-10530-w","DOIUrl":"https://doi.org/10.1007/s12265-024-10530-w","url":null,"abstract":"Recent research shows exercise is good for heart health, emphasizing the importance of physical activity. Sedentary behavior increases the risk of cardiovascular disease, while exercise can help prevent and treat it. Additionally, physical exercise can modulate the expression of lncRNAs, influencing cardiovascular disease progression. Therefore, understanding this relationship could help identify prospective biomarkers and therapeutic targets pertaining to cardiovascular ailments. This review has underscored recent advancements concerning the potential biomarkers of lncRNAs in cardiovascular diseases, while also summarizing existing knowledge regarding dysregulated lncRNAs and their plausible molecular mechanisms. Additionally, we have contributed novel perspectives on the underlying mechanisms of lncRNAs, which hold promise as potential biomarkers and therapeutic targets for cardiovascular conditions. The knowledge imparted in this review may prove valuable in guiding the design of future investigations and furthering the understanding of lncRNAs as diagnostic, prognostic, and therapeutic biomarkers for cardiovascular diseases.","PeriodicalId":15224,"journal":{"name":"Journal of Cardiovascular Translational Research","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2024-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141300764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ASSESS-IE: a Novel Risk Score for Patients with Infective Endocarditis. 评估- ie:感染性心内膜炎患者的一种新的风险评分方法。

IF 4.6 3区医学

Journal of Cardiovascular Translational Research Pub Date : 2024-06-01 Epub Date: 2023-11-15 DOI: 10.1007/s12265-023-10456-9

Xuebiao Wei, Peng Ran, Yuxin Nong, Tao Ye, Xuhua Jian, Younan Yao, Yiwei Xu, Yang Li, Zhonghua Wang, Junqing Yang, Shouhong Wang, Danqing Yu, Jiyan Chen

{"title":"ASSESS-IE: a Novel Risk Score for Patients with Infective Endocarditis.","authors":"Xuebiao Wei, Peng Ran, Yuxin Nong, Tao Ye, Xuhua Jian, Younan Yao, Yiwei Xu, Yang Li, Zhonghua Wang, Junqing Yang, Shouhong Wang, Danqing Yu, Jiyan Chen","doi":"10.1007/s12265-023-10456-9","DOIUrl":"10.1007/s12265-023-10456-9","url":null,"abstract":"Mortality in patients with infective endocarditis (IE) remains high. The existing risk scores are relatively complex with limited clinical application. This study was conducted to establish a new risk model to predict in-hospital and 6-month mortality in IE patients. A total of 1549 adult patients with definite IE admitted to Guangdong Provincial People's Hospital (n=1354) or Xiamen Cardiovascular Hospital (n=195) were included. The derivation cohort consisted of 1141 patients. The score was developed using the multivariate stepwise logistic regression analysis for in-hospital death. Bootstrap analysis was used for validation. Discrimination and calibration were evaluated by the receiver operating characteristic curve and the Hosmer-Lemeshow goodness-of-fit test. Six risk factors were used as score parameters (1 point for each): aortic valve affected, previous valve replacement surgery, severe heart failure, elevated serum direct bilirubin, moderate-severe anemia and acute stage. The predictive value and calibration of the ASSESS-IE score for in-hospital death were excellent in the derivation (area under the curve [AUC]=0.781, p<0.001; Hosmer-Lemeshow p=0.948) and validation (AUC=0.779, p<0.001; Hosmer-Lemeshow p=0.520) cohorts. The score remained excellent in bootstrap validation (AUC=0.783). The discriminatory ability of the ASSESS-IE score for in-hospital (AUC: 0.781 vs. 0.799, p=0.398) and 6-month mortality (AUC: 0.778 vs. 0.814, p=0.040) were similar with that of Park's score which comprised 14 variables. The ASSESS-IE risk score is a new and robust risk-stratified tool for patients with IE, which might further facilitate clinical decision-making.","PeriodicalId":15224,"journal":{"name":"Journal of Cardiovascular Translational Research","volume":" ","pages":"695-704"},"PeriodicalIF":4.6,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"107591379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Systematic Approach Focused on Machine Learning Models for Exploring the Landscape of Physiological Measurement and Estimation Using Photoplethysmography (PPG). 一种系统的方法，专注于机器学习模型，探索利用光体积脉搏图(PPG)进行生理测量和估计的景观。

IF 4.6 3区医学

Journal of Cardiovascular Translational Research Pub Date : 2024-06-01 Epub Date: 2023-11-27 DOI: 10.1007/s12265-023-10462-x

Javed Alam, Mohammad Firoz Khan, Meraj Alam Khan, Rinky Singh, Mohammed Mundazeer, Pramod Kumar

{"title":"A Systematic Approach Focused on Machine Learning Models for Exploring the Landscape of Physiological Measurement and Estimation Using Photoplethysmography (PPG).","authors":"Javed Alam, Mohammad Firoz Khan, Meraj Alam Khan, Rinky Singh, Mohammed Mundazeer, Pramod Kumar","doi":"10.1007/s12265-023-10462-x","DOIUrl":"10.1007/s12265-023-10462-x","url":null,"abstract":"A non-invasive optical technique known as photoplethysmography (PPG) can be used to provide various physiological measurements and estimations. PPG can be used to assess cardiovascular disease (CVD). Hypertension is a primary risk factor for CVD and a major health problem worldwide. PPG is popular because of its important applications in the evaluation of cardiac activity, variations in venous blood volume, blood oxygen saturation, blood pressure and heart rate variability, etc. In this study, we provide a comprehensive analysis of the extraction of various physiological parameters using PPG waveforms. In addition, we focused on the role of machine learning (ML) models used for the estimation of blood pressure and hypertension classification based on PPG waveforms to make future research and innovation recommendations. This study will be helpful for researchers, scientists, and medical practitioners working on PPG waveforms for monitoring, screening, and diagnosis, as a comparative study or reference.","PeriodicalId":15224,"journal":{"name":"Journal of Cardiovascular Translational Research","volume":" ","pages":"669-684"},"PeriodicalIF":4.6,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138444799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0