Journal of Cardiothoracic Surgery最新文献

{"title":"Recurrent purulent cardiac tamponade caused by rupture of an anterior mediastinal teratoma: a case report.","authors":"Jun Gao, Wenyu Zhang, Pan Gao, Hairong Chang, Liye Shao, Jianjun Zhang, Jinrong Wang","doi":"10.1186/s13019-026-04547-2","DOIUrl":"10.1186/s13019-026-04547-2","url":null,"abstract":"<p><p>Mediastinal teratomas are rare germ cell tumors that may present with acute complications, such as rupture, resulting in purulent pericardial effusion and cardiac tamponade. Prompt recognition and intervention are essential to prevent life-threatening deterioration. A 21-year-old previously healthy man presented with acute severe chest pain, dyspnea, and dry cough. Initial chest computed tomography (CT) revealed a 9 × 7 cm anterior mediastinal mass suggestive of teratoma, with minimal pericardial effusion confirmed by echocardiography. Vital signs indicated tachycardia and tachypnea, accompanied by leukocytosis but normal cardiac markers. Within 16 h, the patient developed fever, hypotension, hypoxemia, and oliguria, progressing to septic shock. Bedside ultrasound revealed a large pericardial effusion with signs of tamponade, leading to urgent ultrasound-guided pericardiocentesis that drained purulent fluid. Tumor aspiration confirmed rupture into the pericardial sac, yielding similar purulent material containing hair and fatty globules. Hemodynamic stabilization followed, but the effusion reaccumulated by day 7, requiring repeat pericardiocentesis via a left lateral approach. On hospital day 30, surgical resection revealed a fistula connecting the mass to the pericardium, along with intraoperative findings of pus, hair, sebum, and adhesions. Pathology confirmed a mixed germ cell tumor (predominantly mature teratoma with 5% seminoma). No adjuvant therapy was required. This case highlights the rare yet fulminant complication of mediastinal teratoma rupture leading to purulent pericarditis and tamponade. Bedside ultrasound-guided interventions were pivotal in management, emphasizing the importance of serial monitoring and multidisciplinary care. At 14-month follow-up, the patient remained free of metastasis.</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13673769/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148536008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term outcomes after bentall-de bono versus modified bentall-de bono procedures: a propensity score-matched analysis.","authors":"Song Wang, Meng He, Jinwei Zhang, Peng Sun, Yongqiang Lai, Junming Zhu, Hao Cui, Changwei Ren","doi":"10.1186/s13019-026-04542-7","DOIUrl":"10.1186/s13019-026-04542-7","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the impact of Bentall-de Bono (BD) versus modified Bentall-de Bono (MBD) procedures on patient survival and long-term clinical outcomes.</p><p><strong>Methods: </strong>We reviewed 1,478 patients who underwent Bentall procedures between 2003 and 2022. Patients were initially stratified into two groups based on surgical technique: the BD group (n = 1,274), and the MBD group (n = 204). To mitigate baseline imbalances and selection bias, a 1:1 propensity score matching analysis was performed, yielding 202 matched pairs. Long-term survival was assessed using Kaplan-Meier analysis. Stroke was analyzed as an exploratory secondary cerebrovascular outcome. Predictors of mortality were identified via multivariable Cox proportional hazards regression.</p><p><strong>Results: </strong>In the matched cohort, the median follow-up was 5.98 (interquartile range: 3.53-9.84) years. Kaplan-Meier analysis demonstrated comparable 10-year survival rates between the BD and MBD groups (90.9% vs. 88.4%, P = 0.42). Freedom from stroke was evaluated exploratorily and did not differ significantly between groups. (80.0% vs. 80.2%, P = 0.63). Multivariable Cox regression confirmed that the surgical technique (BD vs. MBD) was not an independent predictor of long-term mortality (hazard ratio [HR], 0.84; 95% confidence interval [CI], 0.40-1.74; P = 0.634). Independent predictors of late mortality included advanced age and prolonged aortic cross-clamp time.</p><p><strong>Conclusion: </strong>There is no difference in long-term survival following BD versus MBD.</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13670466/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148535956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Two Variants in One: Celiomesenteric Trunk with a Proximal SMA-originated Trunk with a Retrograde Hepatic Artery.","authors":"Ampuriire Nyakubaho, Catherine Nagadya, Julius Sewankambo, John Kukiriza","doi":"10.1186/s13019-026-04570-3","DOIUrl":"10.1186/s13019-026-04570-3","url":null,"abstract":"<p><strong>Purpose: </strong>This case report describes an asymptomatic 23-year-old male volunteer in whom an incidental celiomesenteric trunk (CMT) with an associated aberrant retrograde hepatic artery arising from the proximal superior mesenteric artery (SMA) was identified during an educational ultrasound session.</p><p><strong>Methods: </strong>High-resolution ultrasonography with color Doppler was used to visualise the abdominal aorta and its visceral branches in both sagittal and transverse planes.</p><p><strong>Results: </strong>Imaging demonstrated a single common trunk originating from the anterior abdominal aorta, which bifurcated into the celiac trunk and SMA. Additionally, a distinct arterial branch arose from the proximal SMA and coursed superiorly toward the porta hepatis, consistent with a replaced right hepatic artery following a retrograde trajectory.</p><p><strong>Conclusion: </strong>This combination of a CMT and a retrograde replaced right hepatic artery from the proximal SMA represents an uncommon anatomical configuration with direct implications for complex aortic debranching procedures, mesenteric revascularisation, and hepatopancreatobiliary surgery. The case also illustrates the educational value of point-of-care ultrasound in revealing anatomical variations beyond the classic textbook description.</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13670489/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148535954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification and analysis of EphrinB2/EphB4 signaling pathway and angiogenesis related biomarkers in coronary artery disease based on bioinformatics.","authors":"Chunyu Liu, Weiwei Cheng, Xing Wei, Di Song, Zhibiao Zhang","doi":"10.1186/s13019-026-04577-w","DOIUrl":"10.1186/s13019-026-04577-w","url":null,"abstract":"<p><strong>Background: </strong>EphrinB2 and its receptor EphB4 have been reported to play a crucial role in the development of the cardiovascular system, and the process of coronary artery disease (CAD) is closely related to angiogenesis. The aim of this study is to identify and analyze the therapeutic value of the EphrinB2/EphB4 signaling pathway and angiogenesis-related biomarkers.</p><p><strong>Methods: </strong>The CAD chip data (GSE42148) was used for differential analysis to identify differently expressed genes (DEGs). Key module genes associated with CAD were identified using WGCNA. Machine learning and expression validation were executed for screening biomarkers. In addition, the biological functions of biomarkers were explored using enrichment analyses. Finally, the diagnostic and therapeutic value of biomarkers was explored through immune infiltration analysis and drug prediction.</p><p><strong>Results: </strong>Totally, 927 DEGs were identified in CAD and control groups. A total of 1,605 key CAD-related module genes were obtained for subsequent analyses. Then, PTX3, DLL4, and CITED4 were identified as biomarkers. Enrichment analysis suggested that three biomarkers were associated with allograft rejection. Analysis of 28 immune cell infiltrates revealed that CD56dim natural killer cell, eosinophil, mast cell, and MDSC etc. were significantly different between CAD and control groups. Finally, small-molecule drugs, notably simvastatin and calcitriol, were predicted and validated via molecular docking (binding energies < -6.0 kcal/mol) to have a potential therapeutic role in CAD by targeting PTX3 and CITED4, respectively.</p><p><strong>Conclusion: </strong>We obtained three EphrinB2/EphB4 signaling pathway and angiogenesis-related biomarkers (PTX3, DLL4, and CITED4) linked with CAD, which provide new references for the treatment of CAD.</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13673779/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148535915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Technological advances and clinical application of left ventricular assist devices in the treatment of advanced heart failure.","authors":"Chenyu Liu, Yuxiang Zhu","doi":"10.1186/s13019-026-04599-4","DOIUrl":"10.1186/s13019-026-04599-4","url":null,"abstract":"<p><p>Left ventricular assist devices (LVADs) have become an important treatment for advanced heart failure, especially given the shortage of heart transplant donors. This article systematically reviews the technological evolution, perioperative assessment, pathophysiological changes, gender differences, functional recovery, and complication management of LVADs, focusing on the CH-VAD, a fully magnetically levitated centrifugal pump independently developed in China. Results show that LVAD technology has evolved from pulsatile flow devices to the third-generation magnetically levitated centrifugal pump, significantly improving blood compatibility and treatment safety. CH-VAD has demonstrated good efficacy and safety in clinical applications, with a 6-month and 1-year survival rate of 91.6%, a low rate of drive-line infection (11.0%), and unique advantages in complex anatomical cases. LVADs can effectively improve patients' cardiac function, quality of life, and exercise tolerance, promoting cardiac remodeling and skeletal muscle recovery, but hemodynamic regulation during exercise remains limited. The risk of complications (stroke, infection) remains higher in female patients than in male patients. The prediction and management of right heart failure remains a key challenge affecting prognosis. In the future, it is necessary to combine biomarker-guided patient screening, gender-specific risk management, and the technological iteration of domestically produced equipment to promote the individualization and precision of LVAD treatment.</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13673777/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148535935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A very rare case report of circumflex aorta in the cervical vertebral region in an 8-year-old child.","authors":"Amirhossein Jalali, Mohammad Mahdavi, Yaser Toloueitabar, Seyed Salaheddin Nabavi, Mahmoud Ganjifard, Shokoofeh Derakhshan, Seyyed Ebrahim Hosseini Zargaz","doi":"10.1186/s13019-026-04506-x","DOIUrl":"10.1186/s13019-026-04506-x","url":null,"abstract":"<p><strong>Background: </strong>Although circumflex aorta is a rare congenital disease, it can be diagnosed at different ages.</p><p><strong>Case presentation: </strong>This congenital disease has been reported as both right circumflex aorta and left circumflex aorta. To the best of our knowledge, circumflex aorta extending into the cervical/cervical vertebral region is exceptionally rare, with very few comparable reports in the literature. Therefore, in this case, we present our experiences regarding surgical considerations in these patients.</p><p><strong>Conclusion: </strong>Although circumflex aorta is a rare congenital disease given the elevated aortic arch in these patients, meticulous care must be taken to protect the recurrent laryngeal nerve, thyroid gland, and parathyroid glands.</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13663236/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148535878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Complex infective endocarditis with perivalvular abscess and fistulation: two high-risk cases requiring extensive reconstruction and valve replacement.","authors":"Marco Lizwan, Edwin Yosef Widjaja, See Hooi Ewe, Thuan Tong Tan, Teing Ee Tan, Philip Y K Pang","doi":"10.1186/s13019-026-04491-1","DOIUrl":"10.1186/s13019-026-04491-1","url":null,"abstract":"<p><strong>Background: </strong>Infective endocarditis (IE) complicated by aortic root abscess, fistulation and multivalve involvement is rare but carries high mortality. Fistulation from the left ventricular outflow tract (LVOT) to the right atrium (RA) represents an exceptionally uncommon sequela due to extensive perivalvular tissue destruction. Early surgical intervention remains crucial, but postoperative outcomes vary widely depending on host factors, organism control and the feasibility of durable reconstruction.</p><p><strong>Case presentation: </strong>We report two cases of severe aortic valve endocarditis with aortic root abscess and acquired LVOT-RA fistula. The first patient had native-valve Streptococcus mitis endocarditis and underwent aortic and tricuspid valve replacement with double CardioCel patch repair of the fistula. He recovered after transient renal and hepatic dysfunction and completed six weeks of intravenous ceftriaxone. The second patient had prosthetic aortic valve endocarditis with aortomitral curtain destruction, pseudoaneurysm, severe malnutrition, and tricuspid involvement. He underwent redo sternotomy, aortomitral curtain reconstruction, double patch fistula repair, and triple bioprosthetic valve replacement. Although the initial repair was technically satisfactory, he later developed severe mitral paravalvular regurgitation with recurrent Staphylococcus haemolyticus bacteremia and died after deterioration with sepsis and multiorgan dysfunction.</p><p><strong>Conclusion: </strong>These cases illustrate the range of outcomes after complex endocarditis surgery. Patch-based reconstruction may be appropriate when radical debridement leaves sufficient tissue for secure prosthetic seating, whereas extensive prosthetic infection, malnutrition, recurrent bacteremia, and tissue friability increase the risk of late mechanical failure.</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13663161/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148497669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Partial cardiopulmonary bypass in thoracoabdominal aorta repair: a safe alternative in a low-volume center.","authors":"Nicolas Nunez-Ordonez, Julian Senosiain, Juan Andres Sarmiento, Carlos A Villa, Carlos Obando, Tomas Chalela, Mauricio Palomino, Sergio A Ortigoza-Espitia, Ivonne Pineda-Rodriguez, Nestor Sandoval, Jaime Camacho-Mackenzie","doi":"10.1186/s13019-026-04114-9","DOIUrl":"10.1186/s13019-026-04114-9","url":null,"abstract":"<p><strong>Objective: </strong>To describe postoperative outcomes with the use of partial CPB for thoracoabdominal aortic repair.</p><p><strong>Methods: </strong>We included all the patients who underwent programmed thoracoabdominal aortic procedures in which partial cardiopulmonary bypass was used at a single institution. Long term follow-up was collected by review of health records, national databases and via telephone.</p><p><strong>Results: </strong>The study involved 134 patients. Hypertension was present in 78% of patients. The primary surgical indication was an aortic aneurysm (67%), though aortic dissection was also common (33%). Extensive repairs and postoperative complications, such as acute kidney injury and RRT requirement, were significantly associated with increased mortality (p < 0.05). Patients with aortic dissection had worse outcomes, including higher rates of hypertension, stroke, and other complications (p < 0.05). Early mortality was notably higher in extent and II and IV repairs.</p><p><strong>Conclusions: </strong>Thoracoabdominal aorta repair can be safely performed with the use of partial CPB in a low-volume setting when undertaken by a dedicated, experienced Aorta team.</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13663281/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148520549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Papillary fibroelastoma of the mitral valve initially suspected as myxoma: a case report of resection via minimally invasive approach.","authors":"Shota Inoue, Hayate Nomura, Yukihiro Hayatsu","doi":"10.1186/s13019-026-04521-y","DOIUrl":"10.1186/s13019-026-04521-y","url":null,"abstract":"<p><strong>Background: </strong>Papillary fibroelastomas typically arise from the cardiac valves, whereas cardiac myxomas rarely originate from the valves. Distinguishing these tumors intraoperatively can be challenging.</p><p><strong>Case presentation: </strong>An 81-year-old man was referred for evaluation of an incidental cardiac mass. Transesophageal echocardiography revealed a mobile 10-mm mass attached to the P1 segment of the posterior mitral leaflet. Minimally invasive cardiac surgery via a right mini-thoracotomy allowed satisfactory exposure of the mitral valve. Intraoperative findings and frozen section analysis suggested a myxoma, prompting excision with a margin that included the tumor attachment. However, the final histopathological examination revealed papillary fibroelastoma. The postoperative course was uneventful, and the mitral valve function was preserved.</p><p><strong>Conclusions: </strong>Papillary fibroelastomas and myxomas can be difficult to differentiate intraoperatively. Surgical decision-making should balance adequate tumor resection with preserved valve function when a diagnosis is uncertain.</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13663311/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148520554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A potential role of the circ_UBR4/miR-10a-5p/KLF4 axis in regulating vascular smooth muscle cell phenotypic transformation : implications for cardiac allograft vasculopathy.","authors":"Haoqiu Zhong, Zhanyu Xu, Mingyao Zhou, Jieyao Yuan, Jun Peng, Mai Chen, Guoxing Ling, Yibo Yan, Binfeng Lei","doi":"10.1186/s13019-026-04504-z","DOIUrl":"10.1186/s13019-026-04504-z","url":null,"abstract":"<p><p>Cardiac Allograft Vasculopathy (CAV) remains a predominant challenge in post-transplant cardiac care. The phenotypic transformation of vascular smooth muscle cells (VSMCs) is central to its progression, contributing to neointimal hyperplasia and long-term graft failure. Recent studies have highlighted the involvement of non-coding RNAs as essential modulators in VSMC regulation, opening new avenues for therapeutic exploration. In this study, we aimed to explore the role of the circ_UBR4/miR-10a-5p/KLF4 regulatory axis in VSMC phenotypic switching. Human aortic smooth muscle cells (HASMCs) underwent co-transfection with constructed plasmids of both wild-type and mutated sequences for circ_UBR4 and KLF4, along with respective miR-10a-5p mimics or controls. Functional and mechanistic assays, including dual-luciferase reporter analysis, flow cytometry, Transwell migration and invasion assays, qRT-PCR, Western blotting, and immunofluorescence, were utilized to investigate interactions and downstream effects. Our results revealed that circ_UBR4 directly interacts with miR-10a-5p, and its suppression led to attenuated VSMC proliferation and migration. This inhibitory effect was reversed by concurrent miR-10a-5p downregulation, suggesting a functional antagonism. Further analyses demonstrated that miR-10a-5p directly targets KLF4, and its overexpression resulted in decreased proliferative capacity and reduced expression of synthetic and proliferative markers (e.g., OPN, MMP-2, PCNA, and ki-67). These effects were counteracted by KLF4 overexpression. In parallel, contractile marker SM-22α showed opposing trends, further confirming phenotypic transition. Together, these findings suggest that the circ_UBR4/miR-10a-5p/KLF4 axis may play a critical role in regulating VSMC phenotypic plasticity. Insights from this study provide new molecular insights that could inform our understanding of CAV pathogenesis and may represent potential targets for future therapeutic exploration in transplant cardiology.</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13663076/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148520615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}