Journal of Cardiothoracic Surgery最新文献

{"title":"Association between negative T waves in lead V1 and delayed patent ductus arteriosus closure in preterm neonates.","authors":"Hong Meng, Jiangya Wang, Xingxing Jiang, Lei Tian, Tingting Liu, Yuquan Ye","doi":"10.1186/s13019-025-03494-8","DOIUrl":"10.1186/s13019-025-03494-8","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of this study is to determine whether the presence of a negative T wave in lead V1 within 15 h after birth is associated with delayed closure of patent ductus arteriosus (PDA) in preterm neonates within the first week of life.</p><p><strong>Methods: </strong>A retrospective cohort study was conducted involving neonates with a gestational age between 270/70/7 and 411/71/7 weeks who were less than 15 h old and had documented T-wave morphology in lead V1, with PDA confirmed by echocardiography. Neonates with asphyxia, congenital infections, structural heart defects, major malformations, or clinical sepsis were excluded. The cohort was categorized into two groups based on T-wave morphology: Group A (n = 200; normal T wave) and Group B (n = 29; negative T wave). Echocardiographic assessments of PDA closure were performed at different time intervals (days 0-2, 2-5, and 5-7).</p><p><strong>Results: </strong>A total of 229 neonates were included, with a mean gestational age of 35.5 ± 3.23 weeks and a mean birth weight of 2.54 ± 0.78 kg. PDA was diagnosed in 54 neonates (23.6%). Negative T waves in lead V1 were observed in 29 neonates (12.7%) within 15 h after birth, of whom 15 (51.7%) had PDA. The median time to PDA closure differed significantly between Groups A and B, with closure occurring at 2 (0-2), 5 (2-5), and 7 (5-7) days, respectively (log-rank test, p < 0.01). Cox proportional hazards regression analysis identified the presence of a negative T wave in lead V1 as an independent predictor of PDA closure time (adjusted hazard ratio, 0.559; 95% confidence interval: 0.318-0.984).</p><p><strong>Conclusion: </strong>The presence of a negative T wave in lead V1 within 15 h after birth independently predicted a higher likelihood of persistent PDA at day 7 in preterm neonates.</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":"20 1","pages":"240"},"PeriodicalIF":1.5,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12107803/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144159182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Four challenging cases of eosinophilic endocarditis or myocarditis with literature review.","authors":"Ping Chen, Huiling Cheng, Yun Mou","doi":"10.1186/s13019-025-03496-6","DOIUrl":"10.1186/s13019-025-03496-6","url":null,"abstract":"<p><strong>Background: </strong>Eosinophilic endocarditis or myocarditis is a major complication of hypereosinophilic syndrome, characterized by eosinophilic infiltration leading to endocardial or myocardial necrosis, thrombosis formation, and fibrosis. For its rare morbility and various heterogenicity, eosinophilic endocarditis or myocarditis is prone to misdiagnosis and missed diagnosis. Neither large case series nor clinical trials on this specific endocarditis or myocarditis have been reported.</p><p><strong>Case presentation: </strong>Four middle-aged male patients had increased eosinophilia and elevated levels of troponin or lactate dehydrogenase. Cardiac ultrasound showed ventricular wall thickening with or without reduced cardiac systolic function, apical thrombosis or restrictive cardiomyopathy.one of these patients showed myocardial enhancement by CMR, and one of these patients showed endocardial enhancement by CMR. The coronary angiography results were negative. Three patients were diagnosed with eosinophilic endocarditis, and one was diagnosed with eosinophilic myocarditis. After the application of steroid treatment, eosinophil levels decreased rapidly, myocardial thickening was relieved, and cardiac function was gradually recovered.</p><p><strong>Conclusion: </strong>This case series embodies the high heterogeneity in the clinical manifestation of the eosinophilic myocarditis or endocarditis, and the important role of multi-module imaging. Early detection and early treatment is crucial for the prognosis of eosinophilic endocarditis or myocarditis.</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":"20 1","pages":"241"},"PeriodicalIF":1.5,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12107866/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144159173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and safety of mechanical pulmonary valve replacement: a comprehensive systematic review and meta-analysis.","authors":"Ali Rafati, Sina Rashedi, Yeganeh Pasebani, Milad Vahedinejad, Hamed Ghoshouni, Yaser Toloueitabar, Mostafa Mousavizadeh, Sedigheh Saedi, Amirhosein Jalali, Zahra Khajali, Hassan Tatari, Fahimeh Farrokhzadeh, Hooman Bakhshandeh, Maziar Gholampour Dehaki, Behshid Ghadrdoost, Parham Sadeghipour","doi":"10.1186/s13019-025-03471-1","DOIUrl":"10.1186/s13019-025-03471-1","url":null,"abstract":"<p><strong>Background: </strong>Pulmonary valve replacement (PVR) is the most common valve replacement procedure for pulmonary valve dysfunction in congenital heart diseases (CHD). Despite the long-term need for anticoagulation and potential bleeding complications in mechanical PVR (MPVR), prosthetic dysfunction and reoperation might occur less frequently. The major guidelines on the CHD management have no recommendation on the valve type for the PVR. So, we systematically reviewed the latest literature on the efficacy and safety of MPVR with different etiologies.</p><p><strong>Methods: </strong>This study followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. The protocol was registered with PROSPERO (CRD42023425339). A systematic search was conducted in PubMed, Scopus, Web of Science, and Embase. The primary outcomes evaluated include all-cause mortality, reintervention for mechanical prostheses, valvular thrombosis, thromboembolic events, prosthetic valve dysfunction, major bleeding events, right ventricular failure, and infective endocarditis. A random-effects model was employed for the meta-analysis. The quality of the studies was assessed using the Newcastle-Ottawa Scale.</p><p><strong>Results: </strong>The literature search was conducted up to June 12, 2023, and included 16 records in the qualitative synthesis, with 13 studies also included in the quantitative synthesis. Our systematic review indicates that the previously published patient-level analysis remains the most reliable evidence to date on MPVR, with 91%, 97%, and 95% 5-year freedom from valvular thrombosis, reintervention, and all-cause mortality, respectively. Our meta-analysis indicated low pooled incidence proportions of other outcomes as follows: Major bleeding (mean follow-up = 68.79 months, 16/336, 5% [95% CI 3-8]); Valvular dysfunction (mean follow-up = 68.89 months, 70/708, 10% [95% CI 8-12]); Thromboembolic events (mean follow-up = 78.28 months, 9/293, 3% [95% CI 2-6]); and Infectious endocarditis (mean follow-up = 42.03 months, 7/518, 1% [95% CI 1-3]).</p><p><strong>Conclusions: </strong>Despite showing acceptable efficacy and safety in MPVR, there is still a significant knowledge gap in choosing the most appropriate prosthetic valve in patients undergoing PVR. High-quality research is warranted to resolve the existing gap in evidence.</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":"20 1","pages":"238"},"PeriodicalIF":1.5,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12105212/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144150450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic value of baseline glucose levels for mortality in patients with cardiogenic shock: a systematic review and meta-analysis.","authors":"Lisha Wu, Jingjing Cao, Jiuxin Ge","doi":"10.1186/s13019-025-03483-x","DOIUrl":"10.1186/s13019-025-03483-x","url":null,"abstract":"<p><strong>Background: </strong>Baseline glucose levels have been implicated in the prognosis of critically ill patients. However, the prognostic value of glucose in patients with cardiogenic shock (CS) has not been systematically evaluated. The current study aimed to provide evidence that baseline glucose levels can predict mortality in patients with CS.</p><p><strong>Methods: </strong>PubMed, Scopus, Embase and Web of Science were searched from inception to July 31, 2024 for studies assessing mortality after CS based on different baseline glucose levels. Hyperglycemia was defined as a glucose level > 7.8-8 mmol/l. Data were synthesized using \"Review Manager\" (RevMan; version 5.3; The Cochrane Collaboration).</p><p><strong>Results: </strong>A total of nine studies were included. Meta-analysis showed that patients with CS who had baseline glucose levels > 7.8-8 mmol/l had a significantly greater risk of early mortality as compared to those with glucose levels < 7.8-8 mmol/l [risk ratio (RR), 1.48; 95% confidence interval (CI), 1.24-1.77; I-squared (I²) = 65%]. Similarly, patients with CS who had baseline glucose levels > 10-11 mmol/l (RR, 1.98; 95% CI, 1.35-2.90; I² = 82%) and 11.5-12mmol/l (RR, 1.43; 95% CI, 1.19-1.72; I² = 74%) had significantly greater risk of early mortality as compared to those with lower levels. Severe hyperglycemia (> 16 mmol/l) was also associated with an increased risk of mortality compared with normoglycemia (RR, 1.84; 95% CI, 1.36-2.48; I² = 78%).</p><p><strong>Conclusion: </strong>In the present meta-analysis, the elevated risk of mortality was persistent with different glucose cut-offs, suggesting that glucose levels at admission can be useful for risk assessment in patients with CS. Further studies considering diabetes status and other important confounding factors are needed to obtain more evidence.</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":"20 1","pages":"237"},"PeriodicalIF":1.5,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12105281/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144150353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of outcomes between axillary and femoral artery cannulation for type A aortic dissection surgery.","authors":"ZhenHong Wang, YiHui Yu, XinYi Xie, LinLin Wan, Lei Wang, JiaLin Yin","doi":"10.1186/s13019-025-03465-z","DOIUrl":"10.1186/s13019-025-03465-z","url":null,"abstract":"<p><strong>Objective: </strong>To compare the application and outcomes of femoral versus axillary arterial cannulation in adult patients undergoing surgery for type A aortic dissection.</p><p><strong>Methods: </strong>We conducted a retrospective review of 108 patients who underwent surgery for type A aortic dissection, dividing them into two groups based on the type of arterial cannulation utilized: the femoral artery cannulation group (n = 53) and the axillary artery cannulation group (n = 55). We assessed their general condition, cardiopulmonary bypass time, and the occurrence of major postoperative complications. Multivariate logistic regression models were used to identify independent predictors of mortality risk factors.</p><p><strong>Results: </strong>The operative mortality rates were comparable between the two groups, with axillary cannulation at 18.1% and femoral cannulation at 15.1%. Multivariate logistic analysis identified age (70 years or older) and prolonged extracorporeal cardiopulmonary bypass time (250 min or more) as independent risk factors for surgical mortality. The rates of early stroke, renal injury, and cognitive dysfunction were similar in both groups.</p><p><strong>Conclusion: </strong>The findings indicate that femoral and axillary arterial cannulation yield similar outcomes in patients with acute type A aortic dissection. The choice of cannulation site should be individualized based on each patient's specific risk factors. Additionally, preoperative hemodynamic instability, the duration of cardiopulmonary bypass (CPB), and a high body mass index (BMI ≥ 30 kg/m²) are independent predictors of operative mortality.</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":"20 1","pages":"236"},"PeriodicalIF":1.5,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12102863/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144132281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cone reconstruction after carpentier repair in ebstein anomaly: yes we can!","authors":"Alessandro Giamberti, Federica Torchio, Massimo Chessa, Stefan Veljkovic, Ana Perunicic, Aleksandra Nikolic","doi":"10.1186/s13019-025-03344-7","DOIUrl":"10.1186/s13019-025-03344-7","url":null,"abstract":"<p><p>The management of recurrent tricuspid regurgitation (TR) after initial tricuspid valve (TV) repair in patients with Ebstein's anomaly (EA) represents a complex challenge. Traditionally, tricuspid valve replacement has been the first-line option for these patients. The use of Cone Repair for recurrent TR remains under-reported. Herein, we report a successful cone repair for recurrent TR, twelve years after a Carpentier repair in a 39-year-old male patient.</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":"20 1","pages":"235"},"PeriodicalIF":1.5,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12096629/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144119715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ascorbic acid and microcirculation in cardiothoracic surgery: a pilot feasibility trial and matched cohort study.","authors":"Patrick M Wieruszewski, Misty A Radosevich, Scott D Nei, Kianoush B Kashani, Sarah E Normand, Hartzell V Schaff, Erica D Wittwer","doi":"10.1186/s13019-025-03486-8","DOIUrl":"10.1186/s13019-025-03486-8","url":null,"abstract":"<p><strong>Background: </strong>Ascorbic acid is an essential cofactor of catecholamine synthesis that increases capillary bed density and improves microcirculation perfusion. We hypothesized early ascorbic acid administration in cardiothoracic surgery would preserve the microcirculatory integrity and minimize postoperative vasoplegia.</p><p><strong>Methods: </strong>This was a single-arm pilot feasibility study of adults undergoing septal myectomy combined with valve intervention or alone using cardiopulmonary bypass. Intravenous ascorbic acid 1,500 mg was administered before and immediately following cardiopulmonary bypass and every 6 h after for 12 doses. Three historical controls were identified and matched to each trial participant on age, gender, body mass index, preoperative ejection fraction, surgery performed, and time on cardiopulmonary bypass. The feasibility endpoint was a composite of successful and timely 1) ascorbic acid administration, 2) laboratory assessment, and 3) microcirculation measurements across the perioperative phases of care. Clinical endpoints included vasoplegia incidence, acute kidney injury, and lengths of stay compared to controls.</p><p><strong>Results: </strong>Fifteen patients were enrolled and compared to 45 historically matched controls. Participants' median baseline plasma ascorbic acid concentration was 0.5 (0.3, 0.9) mg/dL. Four (27%) patients had suboptimal concentrations. Eleven participants (75%) did not meet the feasibility composite endpoint due to the inability of microcirculation measurement. Incidence of vasoplegia and acute kidney injury, vasopressor duration, and lengths of stay were similar between participants and historical controls. No drug-related adverse events were noted.</p><p><strong>Conclusions: </strong>Timely microcirculation measurements were challenging in the complex cardiothoracic surgery environment. Compared to historical controls, no meaningful differences in clinical endpoints were noted with ascorbic acid treatment. The utility of ascorbic acid on post-cardiopulmonary bypass vasoplegia remains unclear.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov (NCT03744702, registered on November 14, 2018).</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":"20 1","pages":"234"},"PeriodicalIF":1.5,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12096601/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144119713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fatal case of streptococcal prosthetic valve endocarditis caused by Streptococcus mitis in patient with tetralogy fallot disorder: a case report.","authors":"Zahra Jahani, Mina Latifian, Pooria Ahmadi, Saber Esmaeili","doi":"10.1186/s13019-025-03463-1","DOIUrl":"10.1186/s13019-025-03463-1","url":null,"abstract":"<p><strong>Background: </strong>Prosthetic valve Endocarditis (PVE) is an uncommon but potentially life-threatening infection involves a valve prosthesis or annuloplasty ring. Streptococci, including Streptococcus mitis and enterococci are major etiological agents, with studies indicating their significant role in late-onset PVE in some regions of world, staphylococci have surpassed streptococci as the most frequent causative organism. Despite challenges in diagnosis, molecular methods offer high sensitivity.</p><p><strong>Case presentation: </strong>A 30-year-old female patient, Iranian, with a history of hypothyroidism, tetralogy of Fallot, and a bioprosthetic valve replacement and weakness after two months from exprience upper respiratory tract infection (URTI), was admitted with complaints of epistaxis, fever and worsening of shortness of breath. She exhibited symptoms of anemia, thrombocytopenia, elevated WBC, LDH, and D-dimer levels, along with splenomegaly, pleural effusions, and pulmonary congestion. Echocardiography revealed significant valve vegetation and RV failure. Despite comprehensive treatment, including cardiac surgery and antifungal therapy, her condition deteriorated, leading to cardiac arrest and death. Posthumous molecular analysis identified S. mitis as the causative agent, despite negative blood cultures.</p><p><strong>Conclusions: </strong>This case highlights the challenges of diagnosing and treating complex PVE, particularly when conventional cultures are negative. The detection of S. mitis through molecular methods underscores the importance of early and accurate identification of pathogens in guiding effective treatment.</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":"20 1","pages":"233"},"PeriodicalIF":1.5,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12093851/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144110452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"miR-221-3p, arterial blood gas, and lung ultrasound: a multimodal approach for predicting neonatal respiratory distress syndrome outcomes.","authors":"Meixin Liang, Tao Pan, Yanan Hou, Zhihua Liu, Zhiqiang Liu, Jing Mo, Yang Zhang, Jinfeng Wen","doi":"10.1186/s13019-025-03445-3","DOIUrl":"10.1186/s13019-025-03445-3","url":null,"abstract":"<p><strong>Background: </strong>Neonatal respiratory distress syndrome (NRDS) is one of the critical illnesses causing early death in infants due to alveolar surface-active substance deficiency, and the prognosis may show varying degrees of sequelae. Some miRNAs are valuable in the prognosis of NRDS infants. The objective of this research was to assess the predictive value of combining the three factors on the prognosis of NRDS infants by analyzing miR-221-3p levels, arterial blood gas analysis parameters and lung ultrasound (LUS) scores in NRDS infants with good and poor prognosis.</p><p><strong>Methods: </strong>Serum miR-221-3p levels were measured by qRT-PCR. Effect of miR-221-3p expression in prognosis of NRDS infants using Kaplan-Meier curve and COX analyses. Arterial blood gas parameters were analyzed, as well as LUS score was recorded for NRDS infants. Role of miR-221-3p combined with arterial blood gas parameters and LUS score in prognosis of NRDS infants was assessed by ROC curves. Pearson correlation was applied to assess the association of miR-221-3p with arterial blood gas analysis parameters and LUS score.</p><p><strong>Results: </strong>Serum miR-221-3p was notably greater in NRDS infants than in healthy newborns. High miR-221-3p level was related to poor prognosis for NRDS infants. pH and PaO₂ were lower and PaCO₂ was higher in arterial blood gas analysis parameters in poor prognosis. Furthermore, LUS score was greater on poor prognosis as opposed to good prognosis. miR-221-3p combined with arterial blood gas parameters and LUS score has a high accuracy in predicting prognosis in NRDS infants. Moreover, miR-221-3p was associated negatively with pH and PaO₂ and positively with PaCO₂ and LUS score.</p><p><strong>Conclusions: </strong>Elevated miR-221-3p may be related to poor survival outcomes in NRDS infants. miR-221-3p in combination with arterial blood gas parameters and LUS score has a high accuracy in determining the survival outcome of NRDS infants and may be a useful tool for clinical NRDS prognosis.</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":"20 1","pages":"232"},"PeriodicalIF":1.5,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12093823/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144110516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute myocardial infarction and left ventricular thrombus in a young male with thromboangiitis obliterans: a case report and literature review.","authors":"Junyan Zhang, Kai Li, Li Rao, Yong He, Zhongxiu Chen, Xin Wei","doi":"10.1186/s13019-025-03383-0","DOIUrl":"10.1186/s13019-025-03383-0","url":null,"abstract":"<p><p>Thromboangiitis obliterans (TAO) is an inflammatory vascular disease that primarily affects the small- and medium-sized arteries of the extremities. Coronary artery involvement in TAO is rarely reported, and we present the first case of TAO involving the coronary arteries with concomitant left ventricular thrombus. In addition, our case report includes a literature review on coronary artery involvement in TAO and draws comparisons with systemic vasculitis with coronary artery involvement. The case report and literature review aims to offer physicians valuable insights for diagnosis and treatment of TAO with coronary arteries involvement, while also advocating for increased research efforts to explore therapeutic strategies for this rare condition, including both pharmacological treatment and interventional therapy.</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":"20 1","pages":"231"},"PeriodicalIF":1.5,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12085856/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144093678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}