Chinese Journal of Chemistry最新文献

{"title":"Stereoselective Synthesis and Immunological Evaluation of α- and β-Linked Legionaminic Acid Glycoconjugates","authors":"Zhuojia Xu,&nbsp;Xiangyu Wang,&nbsp;Huajie Zhang,&nbsp;Wenxiao Sun,&nbsp;Qi Gao,&nbsp;Zhongrui Ma,&nbsp;Tiehai Li","doi":"10.1002/cjoc.70723","DOIUrl":"https://doi.org/10.1002/cjoc.70723","url":null,"abstract":"<div>\u0000 \u0000 <p>Legionaminic acid (Leg) is a bacteria-specific nonulosonic acid that has emerged as a promising target for the development of pathogen diagnostics and vaccines, especially against critical-priority <i>Acinetobacter baumannii</i>. However, immunological studies of Leg-containing glycoconjugates remain largely unexplored due to the limited availability of structurally well-defined Leg glycosides. Herein, we developed an additive-controlled glycosylation strategy using a 5-<i>N</i>,4-<i>O</i>-carbonyl-protected Leg thioglycoside donor, which enabled the stereoselective synthesis of both α- and β-linked Leg glycosides. To assess their immunological properties, these Leg glycosides were further elaborated into two Leg5,7NAc2-CRM197 glycoconjugates. Immunological evaluation revealed that Leg functions as an antigenic epitope whose antibody specificity is governed by its anomeric configuration.</p>\u0000 <p></p>\u0000 </div>","PeriodicalId":151,"journal":{"name":"Chinese Journal of Chemistry","volume":"44 21","pages":"3401-3405"},"PeriodicalIF":5.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149084037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ligand-Optimized Inorganic Passivation with Alkylammonium Sulfates for Perovskite Photovoltaic","authors":"Jiahui Shen,&nbsp;Ke Zhao,&nbsp;Donger Jin,&nbsp;Jingjing Zhou,&nbsp;Xiaonan Wang,&nbsp;Huaiguo Xue,&nbsp;Rui Wang","doi":"10.1002/cjoc.70778","DOIUrl":"https://doi.org/10.1002/cjoc.70778","url":null,"abstract":"<div>\u0000 \u0000 <p>Perovskite solar cells (PSCs) have reached power conversion efficiencies (PCEs) over 27%, yet further improvements in stability remain critical. Surface passivation is an effective strategy to reduce defects and enhance device durability. Inorganic passivation, in particular, offers stronger chemical bonding and denser protection against moisture and oxygen compared to organic small molecules. Recent studies have employed mild organic ligands to introduce inorganic anions, creating an inorganic passivation layer on the perovskite surface. Here, we report a solution-based passivation approach using sulfate salts coordinated with butylamine, hexylamine, and octylamine, spin-coated onto perovskite surfaces. By tuning the alkylamine chain length, we modulate the passivation effect. With hexylamine sulfate treatment, we achieve a champion PCE of 26.3% for small-area devices and 23.4% for mini solar modules with an active area of 20.8 cm². Moreover, under continuous illumination at 60 °C during maximum power point (MPP) tracking, the devices retain 97.2% of their initial efficiency after 600 h. Our results demonstrate that ligand-optimized inorganic passivation using alkylammonium sulfates enables both high efficiency and excellent operational stability.</p>\u0000 <p></p>\u0000 </div>","PeriodicalId":151,"journal":{"name":"Chinese Journal of Chemistry","volume":"44 21","pages":"3421-3426"},"PeriodicalIF":5.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149084042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[OH-TEMPO]+[NO3]–: A Metal-Free and Cost-Effective Catalyst for Aerobic Oxidation of Alcohols","authors":"Wanqi Sun,&nbsp;Jiayi Dong,&nbsp;Zijie Yu,&nbsp;Zeyu Wen,&nbsp;Jia Yao,&nbsp;Yongtao Wang,&nbsp;Haoran Li","doi":"10.1002/cjoc.70775","DOIUrl":"https://doi.org/10.1002/cjoc.70775","url":null,"abstract":"<div>\u0000 \u0000 <p>The development of sustainable methods for the oxidation of alcohols to aldehydes or ketones remains an important goal in synthesis. In this work, we synthesized a series of nitrate-bearing oxoammonium salts and demonstrated their efficiency as metal-free catalysts for the aerobic oxidation of alcohols. These catalysts operate under mild conditions and exhibit a broad substrate scope, efficiently oxidizing both primary and secondary alcohols. The catalytic system performs effectively on a gram scale with industrially relevant substrates, providing a valuable alternative to current protocols. The system operates via a hydride-transfer mechanism and a self-sustained NO<i>ₓ</i>-mediated redox cycle, with molecular oxygen as the terminal oxidant.</p>\u0000 <p>\u0000 </p>\u0000 </div>","PeriodicalId":151,"journal":{"name":"Chinese Journal of Chemistry","volume":"44 21","pages":"3413-3420"},"PeriodicalIF":5.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149084172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to “Side Chain Engineering of Non-fused Ring Electron Acceptors for Organic Solar Cells”","authors":"","doi":"10.1002/cjoc.70826","DOIUrl":"https://doi.org/10.1002/cjoc.70826","url":null,"abstract":"<p>Side Chain Engineering of Non-fused Ring Electron Acceptors for Organic Solar Cells</p><p>Xia Zhou, Wenkui Wei,* and Chunhui Duan*</p><p>Chin. J. Chem. 2026, 44, 2225–2242.</p><p>DOI: 10.1002/cjoc.70570</p><p>The grant number was incorrectly listed as “2024YFB4611500”. The correct grant number should be “2024YFB3211500”.</p>","PeriodicalId":151,"journal":{"name":"Chinese Journal of Chemistry","volume":"44 21","pages":""},"PeriodicalIF":5.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cjoc.70826","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149083970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enantioselective (3+2) Cycloaddition–Rearrangement Strategy to Access Benzo[d]isothiazole-Containing Polyheterocycles","authors":"Hui-Ling Qian,&nbsp;Wen-Tao Gao,&nbsp;Ming-Zhou Liao,&nbsp;Yi-Ping Liu,&nbsp;Lei Yang,&nbsp;Shu-Pei Yuan,&nbsp;Yong You,&nbsp;Zhen-Hua Wang,&nbsp;Wei-Cheng Yuan,&nbsp;Jian-Qiang Zhao","doi":"10.1002/cjoc.70756","DOIUrl":"https://doi.org/10.1002/cjoc.70756","url":null,"abstract":"<div>\u0000 \u0000 <p>Benzo[<i>d</i>]isothiazole motif has emerged as a privileged structure in medicinal chemistry and agricultural science. However, conventional synthetic methods are plagued by tedious multistep procedures, low atom economy and harsh reaction conditions, rendering the development of a facile and convenient approach for the synthesis of compounds containing a benzo[<i>d</i>]isothiazole moiety highly desirable. We herein present a one-pot enantioselective protocol that integrates a dearomative (3+2) cycloaddition of 2-nitrobenzofurans with 2-(<i>N</i>-2,2,2-trifluoroethyl)benzothiophene-derived ketimines and a subsequent DPPH-mediated rearrangement. This methodology affords an efficient route to enantiomerically pure benzo[<i>d</i>]isothiazole-containing polyheterocyclic derivatives in excellent outcomes (up to 95% yield, &gt; 20 : 1 dr and 99% ee). The synthetic utility of this protocol is further substantiated by scale-up synthesis, downstream transformations, as well as late-stage modification of biologically active molecules.</p>\u0000 <p></p>\u0000 </div>","PeriodicalId":151,"journal":{"name":"Chinese Journal of Chemistry","volume":"44 21","pages":"3406-3412"},"PeriodicalIF":5.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149083988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Siloxane-Based Additives via Electronic Structure Tailoring: A Key Strategy for High-Efficiency and Stable Organic Solar Cells Compatible with Air and Green Solvent Processing†","authors":"Xing Chen,&nbsp;Mingqing Chen,&nbsp;Lianjie Zhang,&nbsp;Dongge Ma,&nbsp;Junwu Chen","doi":"10.1002/cjoc.70746","DOIUrl":"https://doi.org/10.1002/cjoc.70746","url":null,"abstract":"<div>\u0000 \u0000 <p>To advance organic solar cells (OSCs) commercialization, high efficiency and stable devices processed in air and eco-friendly conditions are essential. Herein, two siloxane-based additives, Th-SiO incorporating an electron-donating thiophene unit and Qx-SiO incorporating an electron-deficient quinoxaline unit, were developed. The two retained additives exhibited excellent multifunctionality. In the PM6:L8-BO system, they could effectively regulate intermolecular interactions and active layer morphology, optimize charge transport, and suppress charge recombination. The two additives significantly enhanced the photovoltaic performance of devices fabricated under N₂ and high-humidity air conditions, while also enabling high-performance air processing with a non-halogenated green solvent. Both additives showed good universality. When using 2PACz as the hole transporting layer material, Th-SiO-processed D18:L8-BO devices achieved an efficiency of 20.39%. In the PM6:L8-BO system, the additives Th-SiO and Qx-SiO improved the light and thermal stabilities of the devices simultaneously, yet exhibited different characteristics: Qx-SiO-processed devices showed superior light stability, whereas Th-SiO-processed devices exhibited better thermal stability. The research provides valuable insights for the chemical structure design of novel multifunctional additives.</p>\u0000 <p></p>\u0000 </div>","PeriodicalId":151,"journal":{"name":"Chinese Journal of Chemistry","volume":"44 21","pages":"3441-3452"},"PeriodicalIF":5.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149084041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recent Advances in Asymmetric Electrochemical Synthesis","authors":"Cheng Huang,&nbsp;Yingqi Yang,&nbsp;Kang Liang,&nbsp;Xiuwen Zheng,&nbsp;Ping Hu,&nbsp;Jin Song,&nbsp;Qingquan Lu,&nbsp;Chang Guo","doi":"10.1002/cjoc.70759","DOIUrl":"https://doi.org/10.1002/cjoc.70759","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Comprehensive Summary</h3>\u0000 \u0000 <p>Asymmetric organic electrosynthesis has the core value of precisely combining the clean characteristics of electrochemistry with the high selectivity of organic synthesis. This technology utilizes electrons as ideal redox reagents, fundamentally avoiding the reliance on stoichiometric reductants or hazardous oxidants in traditional methods, and meeting the development requirements of sustainable chemistry. By precise regulation of potential and current, the reaction can selectively generate highly reactive intermediates (such as radicals and radical ions) under mild conditions, opening up a unique pathway for efficient asymmetric synthesis and demonstrating great potential in the synthesis of chiral drug molecules, natural products, and functional materials. Currently, asymmetric organic electrosynthesis based on transition-metal catalysis, organocatalysis, and biocatalysis is flourishing, and a systematic research system has been established to achieve asymmetric coupling and functionalization reactions of various radicals. This review summarizes the research progress made in the field of asymmetric electrosynthesis since 2019, and the mechanistic considerations are comprehensively discussed, including asymmetric anodic oxidation, cathodic reduction, and paired electrolysis. Furthermore, we provide critical insights into future directions and potential challenges in this field, highlighting opportunities for further methodology development and applications for asymmetric electrosynthesis. With the continuous breakthroughs in basic research and technological innovation, asymmetric organic electrosynthesis is expected to become an indispensable core tool in chiral chemistry.</p>\u0000 \u0000 <p>\u0000 </p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Key Scientists</h3>\u0000 \u0000 <p>KEY PLAYERS in the field of asymmetric electrochemical synthesis.</p>\u0000 \u0000 <p>\u0000 </p>\u0000 </section>\u0000 </div>","PeriodicalId":151,"journal":{"name":"Chinese Journal of Chemistry","volume":"44 21","pages":"3530-3555"},"PeriodicalIF":5.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149083955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recent Advances in Transition Metal-Catalyzed Asymmetric Radical C–C Bond Construction","authors":"Fu-Li Wang,&nbsp;Tingting Xia,&nbsp;Yifeng Chen,&nbsp;Xin-Yuan Liu","doi":"10.1002/cjoc.70741","DOIUrl":"https://doi.org/10.1002/cjoc.70741","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Comprehensive Summary</h3>\u0000 \u0000 <p>Radical reactions have emerged as powerful tools for carbon–carbon bond formation, offering complementary advantages to conventional ionic pathways. Nevertheless, the development of asymmetric radical transformations has long remained a formidable challenge, primarily because the high intrinsic reactivity and short lifetime of radical intermediates often lead to competitive racemic background reactions. In recent years, chiral transition-metal catalysts have provided effective platforms to address these issues. Depending on the reaction manifold, chiral metal catalysts can participate in radical generation, activate reacting fragments, or intercept externally generated radicals, thereby enabling stereocontrolled C–C bond formation within a chiral catalytic environment. In this review, we summarize recent advances in transition-metal-catalyzed asymmetric radical C–C bond construction, with an emphasis on enantioselective radical cross-couplings that forge C(sp³)–C(sp), C(sp³)–C(sp²), and C(sp³)–C(sp³) bonds, as well as enantioselective radical additions to C=C, C=O, and C=N bonds. Representative modes of radical generation, including hydrogen-atom transfer (HAT), halogen-atom transfer (XAT), single-electron oxidation, and single-electron reduction, are also discussed. Finally, we highlight current limitations and future opportunities in this rapidly evolving field.</p>\u0000 \u0000 <p></p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Key Scientists</h3>\u0000 \u0000 <p></p>\u0000 \u0000 <p></p>\u0000 </section>\u0000 </div>","PeriodicalId":151,"journal":{"name":"Chinese Journal of Chemistry","volume":"44 21","pages":"3489-3529"},"PeriodicalIF":5.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149084090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inside Cover Picture","authors":"","doi":"10.1002/cjoc.70821","DOIUrl":"https://doi.org/10.1002/cjoc.70821","url":null,"abstract":"<p>Molecular-level design is an effective strategy for constructing high-performance adsorbents for water purification. Two hydrophilic heptazine-based hypercrosslinked polymers featuring abundant hydroxyl groups, high surface area, and intrinsic hydrophilicity were developed. These materials exhibit ultrafast adsorption kinetics, exceptional adsorption capacities, and excellent recyclability toward aromatic organic micropollutants, providing a promising platform for efficient wastewater treatment. More details are discussed in the article by Zhang <i>et al</i>. on pages 3481—3488.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":151,"journal":{"name":"Chinese Journal of Chemistry","volume":"44 21","pages":""},"PeriodicalIF":5.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cjoc.70821","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149083972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Concise Generation and Diazo-Preserving Diversification of β-Diazoimines","authors":"Jiabao Tian,&nbsp;Yanan Wang,&nbsp;Mingqiang Li,&nbsp;Jinxin Liu,&nbsp;Lei Zhou","doi":"10.1002/cjoc.70757","DOIUrl":"https://doi.org/10.1002/cjoc.70757","url":null,"abstract":"<div>\u0000 \u0000 <p>Irradiation of a mixture of vinyldiazo esters and azides with blue light, in the absence of any photocatalyst or additive, generates unconventional β-diazoimines. Mechanistically, the reaction involves the selective decomposition of vinyldiazo compounds under blue light to form singlet free vinylcarbenes, which undergo intramolecular [2+1] cyclization to produce unstable cyclopropene-1-carboxylates. These intermediates subsequently participate in a 1,3-dipolar cycloaddition with azides, followed by ring-opening via retro-1,3-dipolar cycloaddition to generate β-diazoimines. One-pot, diazo-preserving diversifications of β-diazoimines provide access to α-diazoesters bearing distal functional groups that are otherwise difficult to introduce. These transformations include nucleophilic addition and reduction to give γ-amino-α-diazoacetates, as well as oxidation to afford β-carboxamido-α-diazoesters. The synthetic potential of these unusual diazo compounds was demonstrated. For example, Rh(II)-catalyzed N–H insertion of γ-amino-α-diazoester afforded azetidine, while reduction of its diazo group with P^<i>n</i>Bu₃ promoted an intramolecular aminolysis to yield a γ-lactam product. Interestingly, controllable intramolecular 1,3-C–H and 1,4-N–H insertion reactions of β-carboxamido-α-diazoester were achieved using different catalyst systems, providing cyclopropane and β-lactam derivatives, respectively.</p>\u0000 <p></p>\u0000 </div>","PeriodicalId":151,"journal":{"name":"Chinese Journal of Chemistry","volume":"44 21","pages":"3427-3432"},"PeriodicalIF":5.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149084043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}