Journal of Behavioral and Brain Science最新文献_第2页

Specific components of child gestures at 14 months are associated with preschoolers’ language skills 14个月大的儿童手势的特定组成部分与学龄前儿童的语言技能有关

Journal of Behavioral and Brain Science Pub Date : 2020-01-01 DOI: 10.20821/JBS.49.0_5

Yuko Ibara, Tomoko Nishimura, Ryuji Nakahara, Toshiki Iwabuchi, Taeko Harada, Akemi Okumura, Chikako Nakayasu, N. Takei, K. Tsuchiya

引用次数: 0

Ghrelin signaling attenuates the inflammatory activation of neuroimmune system in senescence. 促生长素信号可减弱衰老过程中神经免疫系统的炎症激活。

Journal of Behavioral and Brain Science Pub Date : 2020-01-01 DOI: 10.20821/JBS.49.0_63

K. Endo, Hiroyuki Morimoto, Hayato Asai, Million Hong, Haruka Amitani, A. Asakawa, S. Mikawa, Kohji Sato, Y. Ueki, Koichi Inoue, T. Ueki, H. Okamoto, T. Otsuka, H. Murakami

引用次数: 0

Why is methylphenidate effective in ADHD 为什么哌甲酯对ADHD有效

Journal of Behavioral and Brain Science Pub Date : 2018-01-01 DOI: 10.20821/JBS.48.0_5

Kohji Sato

{"title":"Why is methylphenidate effective in ADHD","authors":"Kohji Sato","doi":"10.20821/JBS.48.0_5","DOIUrl":"https://doi.org/10.20821/JBS.48.0_5","url":null,"abstract":"Attention deficit hyperactivity disorder (ADHD) is one of the most prevalent neurobehavioral disorders. Methylphenidate (MPH) is a psychostimulant widely used for the treatment of ADHD. MPH is an inhibitor of dopamine transporter (DAT), and increases dopamine (DA) levels by inhibiting dopamine uptakes in patient brains. On the other hand, the involvement of NMDA type glutamate receptors (NMDARs) in the pathogenesis of ADHD has been also postulated. Magnetic resonance spectroscopy (MRS) study showed a decrease of combined glutamate/glutamine to creatinine ratio in the right anterior cingulated cortex in ADHD adults. In addition, a NMDA subunit gene polymorphism (GRIN2B rs2284411) has been reported to be an important predictor of MPH response in ADHD. Taken together, NMDAR functions are somehow disturbed in ADHD. However, the relationship between the increment of dopamine levels and the improvement of NMDAR functions is largely unknown. Recently, Shibasaki et al. have reported that DA Journal of Brain Science, January 25, 2018,Vol.48 6 causes a functional reversal of glycine transporter 1 (GlyT1), causing astrocytes to release glycine. Glycine is a very important co-agonist for NMDARs and plays a role in treating ADHD by modulating the glutamatergic neurotransmission system through activating NMDARs. Thus, I postulate the following hypothesis. MPH blocks DAT and increases dopamine levels. The increment of dopamine levels activates astrocyte to release glycine. The increment of glycine levels improves NMDAR functions, resulting in improvement of ADHD. Key wards: ADHD, dopamine, glycine, glycine transporter","PeriodicalId":15186,"journal":{"name":"Journal of Behavioral and Brain Science","volume":"6 1","pages":"5-13"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84778432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Investigation of the reliability and validity of the Japanese Deliberate Self-Harm Inventory 日本人故意自残量表信效度调查

Journal of Behavioral and Brain Science Pub Date : 2018-01-01 DOI: 10.20821/JBS.48.0_14

T. Ohira, T. Munesue, Manabu Oi, Kunitake Suzuki, D. Saito

引用次数: 2

Individual Schema Therapy for high-functioning autism spectrum disorder with comorbid psychiatric conditions in Young Adults: Results of a Naturalistic Multiple Case Study 个体图式疗法治疗年轻成人高功能自闭症谱系障碍合并精神疾病:一项自然多病例研究的结果

Journal of Behavioral and Brain Science Pub Date : 2018-01-01 DOI: 10.20821/JBS.48.0_43

Fumiyo Oshima, Ida A. Shaw, Toshiyuki Ohtani, Kazunori Iwasa, Hirofumi Nishinaka, A. Nakagawa, E. Shimizu

引用次数: 2

Positively worded subscale score of the Perceived Stress Scale is associated with cognitive domain function. 感知压力量表的正向分量表得分与认知领域功能相关。

Journal of Behavioral and Brain Science Pub Date : 2017-07-01 Epub Date: 2017-07-24 DOI: 10.4236/jbbs.2017.77023

Julie M Jiang, Elizabeth K Seng, Molly E Zimmerman, Mimi Kim, Richard B Lipton

{"title":"Positively worded subscale score of the Perceived Stress Scale is associated with cognitive domain function.","authors":"Julie M Jiang, Elizabeth K Seng, Molly E Zimmerman, Mimi Kim, Richard B Lipton","doi":"10.4236/jbbs.2017.77023","DOIUrl":"10.4236/jbbs.2017.77023","url":null,"abstract":"Objectives: To examine the cross-sectional associations of the separate subscales of the Perceived Stress Scale (PSS) and tests measuring cognitive domains in older adults.Methods: 897 adults over the age of 70 free of amnestic mild cognitive impairment and dementia and enrolled in the Einstein Aging Study made up the study sample. The PSS-14 was used to measure stress. Three cognitive domains (language, episodic memory, and frontal-executive) had previously been found using principle component analysis. Linear regression analyses were used to determine the relationship between the PSS subscales and cognitive domain function.Results: The study sample had a mean age of 79.1 years and 62.8% were female. Bivariate correlations show that the PSS-14 positively worded subscale of the PSS (PSS-PW) was significantly associated with all three cognitive domains (language: r = -0.15, p < 0.001; episodic memory: r = -0.16, p < 0.001; frontal-executive: r = -0.21, p <0.001) while the negatively worded subscale of the PSS (PSS-NW) was not significantly associated with any cognitive domain. In linear regression analyses adjusted for age, white race, gender, years of education, and depressive symptoms, the PSS-PW remained significantly associated with each of the cognitive domains. The PSS-NW was not associated with any cognitive domains in any model. The PSS-14 was significantly associated with language and episodic memory, but not the frontal-executive domain.Conclusion: Worse PSS-PW scores are associated with reduced cognitive function in the executive, memory, and language domains in nondemented older adults. The PSS-PW subscale correlated better with cognitive function than the overall PSS-14. Future research should evaluate the temporality of the association and if stress reduction therapies improve cognitive performance.","PeriodicalId":15186,"journal":{"name":"Journal of Behavioral and Brain Science","volume":"7 7","pages":"311-324"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777589/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35769413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

How does being bilingual influence children with autism in the aspect of executive functions and social and communication competence 双语对自闭症儿童的执行能力、社交能力和沟通能力有何影响

Journal of Behavioral and Brain Science Pub Date : 2017-06-21 DOI: 10.20821/JBS.47.0_21

Li HiuKei, Oi Manabu, Gondo Keiko, Matsui Tomoko

{"title":"How does being bilingual influence children with autism in the aspect of executive functions and social and communication competence","authors":"Li HiuKei, Oi Manabu, Gondo Keiko, Matsui Tomoko","doi":"10.20821/JBS.47.0_21","DOIUrl":"https://doi.org/10.20821/JBS.47.0_21","url":null,"abstract":"Background Bilingual families with children with autism often struggle with the dilemma of their as they are usually advised by professionals to use only one language to avoid the risk of language delay and confusion. However, there is no scientific base to such advice. Two-way ANOVA was used to analyze the accuracy and latency of EF tasks and the score of questionnaires on social and communication competence. No significant differences were found between groups except between TD and ASD in the Japanese version of Stroop task and the scores of the social and communication competence questionnaires. Significant difference was found between the bilingual ASD and the Japanese monolingual ASD at the latency of the English version of Stroop task but stroop effect was not significantly different. study suggests that being bilingual for children with ASD does not impede their EF and social and communication competence. Professionals should consider the family cultural background and language use before suggesting the ‘one language only’ advice as it can scar the family dynamics and deprive the child’s opportunity to be fully involved in the family.","PeriodicalId":15186,"journal":{"name":"Journal of Behavioral and Brain Science","volume":"5 1","pages":"21-49"},"PeriodicalIF":0.0,"publicationDate":"2017-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74520625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 14

Translating Interdisciplinary Research on Language Learning into Identifying Specific Learning Disabilities in Verbally Gifted and Average Children and Youth. 将跨学科语言学习研究转化为识别语言天赋和普通儿童及青少年的特殊学习障碍。

Journal of Behavioral and Brain Science Pub Date : 2017-06-01 Epub Date: 2017-06-16 DOI: 10.4236/jbbs.2017.76017

Ruby Dawn Lyman, Elizabeth Sanders, Robert D Abbott, Virginia W Berninger

{"title":"Translating Interdisciplinary Research on Language Learning into Identifying Specific Learning Disabilities in Verbally Gifted and Average Children and Youth.","authors":"Ruby Dawn Lyman, Elizabeth Sanders, Robert D Abbott, Virginia W Berninger","doi":"10.4236/jbbs.2017.76017","DOIUrl":"10.4236/jbbs.2017.76017","url":null,"abstract":"The current research was grounded in prior interdisciplinary research that showed cognitive ability (verbal ability for translating cognitions into oral language) and multiple-working memory endophenotypes (behavioral markers of genetic or brain bases of language learning) predict reading and writing achievement in students with and without specific learning disabilities in written language (SLDs-WL). Results largely replicated prior findings that verbally gifted with dyslexia score higher on reading and writing achievement than those with average verbal ability but not on endophenotypes. The current study extended that research by comparing those with and without SLDs-WL with assessed verbal ability held constant. The verbally gifted without SLDs-WL (n = 14) scored higher than the verbally gifted with SLDs-WL (n = 27) on six language skills (oral sentence construction, best and fastest handwriting in copying, single real word oral reading accuracy, oral pseudoword reading accuracy and rate) and four endophenotypes (orthographic and morphological coding, orthographic loop, and switching attention). The verbally average without SLDs-WL (n = 6) scored higher than the verbally average with SLDs-WL (n = 22) on four language skills (best and fastest handwriting in copying, oral pseudoword reading accuracy and rate) and two endophenotypes (orthographic coding and orthographic loop). Implications of results for translating interdisciplinary research into flexible definitions for assessment and instruction to serve students with varying verbal abilities and language learning and endophenotype profiles are discussed along with directions for future research.","PeriodicalId":15186,"journal":{"name":"Journal of Behavioral and Brain Science","volume":"7 6","pages":"227-246"},"PeriodicalIF":0.0,"publicationDate":"2017-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7085111/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37762116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Conversations between individuals with autism and typical development: similarities, differences, and exchange characteristics and patterns from the perspective of verbal response modes 自闭症个体与典型发育者的对话:从言语反应模式看对话的异同及交流特征与模式

Journal of Behavioral and Brain Science Pub Date : 2017-01-01 DOI: 10.20821/JBS.47.0_50

Sakiko Koshimura, T. Munesue, Hiroyuki Nakamura, Manabu Oi

引用次数: 0

BMP signaling-related proteins are differentially expressed in the adult cerebellum BMP信号相关蛋白在成人小脑中有差异表达

Journal of Behavioral and Brain Science Pub Date : 2016-09-16 DOI: 10.20821/JBS.46.0_70

Gandhervin Kesavamoorthy, S. Mikawa, Y. Kusakawa, Tomonori Sato, M. Miyagi, S. Yamagishi, Kohji Sato

引用次数: 0