Journal of Biomimetics, Biomaterials and Biomedical Engineering最新文献_第5页

Evaluation of Newly Formulated Chlorhexidine Mouthwash 新配方洗必泰漱口水的评价

Journal of Biomimetics, Biomaterials and Biomedical Engineering Pub Date : 2023-10-24 DOI: 10.4028/p-dppua9

Peerapong Tua-Ngam, Ratchaporn Srichan, Arthit Klaophimai, Pachara Rudrakanjana, Thanattha Wuttihasa, Rattiporn Kaypetch

引用次数: 0

Scaffold of Bone Tissue Engineering Based on PVA/BCP Bioactive Composite Foam 基于PVA/BCP生物活性复合泡沫的骨组织工程支架

IF 0.7

Journal of Biomimetics, Biomaterials and Biomedical Engineering Pub Date : 2023-07-31 DOI: 10.4028/p-xBhp5F

F. Hashim, Wafaa A. Hussain, M. Ismail, Ahmed Amr, Abdulqadher M. Daham, Luay H. Alwan

{"title":"Scaffold of Bone Tissue Engineering Based on PVA/BCP Bioactive Composite Foam","authors":"F. Hashim, Wafaa A. Hussain, M. Ismail, Ahmed Amr, Abdulqadher M. Daham, Luay H. Alwan","doi":"10.4028/p-xBhp5F","DOIUrl":"https://doi.org/10.4028/p-xBhp5F","url":null,"abstract":"This study constructed poly (vinyl alcohol)/ biphasic-calcium phosphate (PVA/ BCP) composite scaffolds. The biphasic-calcium phosphate (BCP) was incorporated in 0, 5, 10, and 25 wt%; BP0, BP1, BP2, and BP3, respectively. The surface morphology was done with a scanning electron microscope (SEM) to observe the porosity and the pore size and distribution of fabricated samples. The Fourier Transform Infrared spectroscopy (FTIR), and some physical properties such as porosity, density, swelling ratio, flexural strength, impact strength, and compression strength were also investigated. The biodegradation and bioactivity were also tested. The SEM results showed that the pores increased and became more regular and interconnected to each other with the increasing addition of BCP. The density decreased with the addition of BCP, while the porosity and mechanical properties increased with additives. The sample of BP3 has a high porosity (67%) and high impact strength (11.9 MPa). The high porosity is favorable for bone implants, and the mechanical strength must also be considered. The bio tests show that the biodegradation became regular by adding the BCP powder, which leads to ease of controlling the gradual degradation and the samples are bioactive for bone tissue. Keywords: Bone Tissue Engineering, PVA, Biphasic-Calcium Phosphate, Porosity, Mechanical properties","PeriodicalId":15161,"journal":{"name":"Journal of Biomimetics, Biomaterials and Biomedical Engineering","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47679507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

LLDPE/TiO2-ZnO Nanocomposite Films induces Transitory Oxidative Stress Response on Human Fibroblast and Blood Cell Lines Models LLDPE/TiO2-ZnO纳米复合膜诱导人成纤维细胞和血细胞模型的瞬态氧化应激反应

IF 0.7

Journal of Biomimetics, Biomaterials and Biomedical Engineering Pub Date : 2023-07-31 DOI: 10.4028/p-2aa27K

Nor Hazliana Harun, R. Mydin, S. Sreekantan, Khairul Arifah Saharuddin, A. Seeni

{"title":"LLDPE/TiO2-ZnO Nanocomposite Films induces Transitory Oxidative Stress Response on Human Fibroblast and Blood Cell Lines Models","authors":"Nor Hazliana Harun, R. Mydin, S. Sreekantan, Khairul Arifah Saharuddin, A. Seeni","doi":"10.4028/p-2aa27K","DOIUrl":"https://doi.org/10.4028/p-2aa27K","url":null,"abstract":"Healthcare-associated infections (HAIs) are a major safety concern globally that contribute to mortality rates amongst patients especially associated with indwelling or implanted medical devices. The advanced metal-oxide nanocomposites (MNPs) embedded in polymer matrix present an outstanding antibacterial profile, especially for MDR strains owing to reactive oxygen species (ROS) and free radicals’ mode of action. To date, there is still a lack of knowledge on the implication of external reactive species from MNPs-based polymers to humans. This study investigates the bio-interaction of TiO2-ZnO nanocomposite films embedded in linear low-density polyethylene (LLDPE/ TiO2-ZnO) on human fibroblast and blood cell lines model at molecular genes and protein level. The initial analysis of the in vitro bio-interaction responses on fibroblast and blood cell line models showed signs of cell membrane integrity disturbance, which might be due to free radicals’ activities, such as the release of intracellular ROS and Zn ions (Zn2+) during the initial cellular adaptation process on the TiO2–ZnO polymer nanocomposite film. Further findings found that cell–polymer nanocomposite film interaction could possibly trigger transitory oxidative stress response and cellular redox regulation via NF-kβ interactions. However, further comprehensive studies are needed to support this study, especially involving animal models.","PeriodicalId":15161,"journal":{"name":"Journal of Biomimetics, Biomaterials and Biomedical Engineering","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45990774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of Novel Prosthesis Implant Adapter by Finite Element Analysis 基于有限元分析的新型假体种植接头评价

IF 0.7

Journal of Biomimetics, Biomaterials and Biomedical Engineering Pub Date : 2023-07-31 DOI: 10.4028/p-N2yzeB

Marwa J. Jamal, S. Hamandi, M. N. Arbilei

引用次数: 1

Functionalization of Chitosan-TiO2 Nanotubes Scaffolds with Fibronectin for Bone Regeneration 壳聚糖-TiO2纳米管支架与纤连蛋白的功能化骨再生

IF 0.7

Journal of Biomimetics, Biomaterials and Biomedical Engineering Pub Date : 2023-07-31 DOI: 10.4028/p-k9wk3T

S. Lim, C. Chiang, N. Rosli, K. Chew

{"title":"Functionalization of Chitosan-TiO2 Nanotubes Scaffolds with Fibronectin for Bone Regeneration","authors":"S. Lim, C. Chiang, N. Rosli, K. Chew","doi":"10.4028/p-k9wk3T","DOIUrl":"https://doi.org/10.4028/p-k9wk3T","url":null,"abstract":"Composite scaffolds are promising regenerative medicines. Chitosan-TiO2 nanotubes (CTNTs) scaffold as a composite scaffold is, however, associated with low biocompatibility. This research aims to increase in vitro efficacy of CTNTs scaffolds by using fibronectin (FN) and investigate the adsorption affinity of such scaffolds towards FN. CTNTs scaffolds were prepared via direct blending of TiO2 nanotubes (TNTs) and chitosan solution. The mixture was then subjected to 24-h freezing and 24-h freeze drying. The scaffolds were further functionalized with FN solution (20, 40, 60, 80 and 100 μg/mL) via adsorption. The amount of adsorbed FN by the scaffolds was determined via colorimetric method. MG63 was used to evaluate the in vitro efficacy of CTNTs scaffolds with FN. The adsorption affinity of CTNTs scaffolds towards FN was high, as no saturation was achieved. The adsorption isotherm of FN onto CTNTs scaffolds fitted well with Temkin isotherm suggesting there was electrostatic interaction between the scaffolds and FN. Enhanced proliferation and early differentiation were observed in MG63 cultured on CTNTs scaffolds with FN. Particularly, CTNTs scaffolds functionalized with 60 μg/mL FN promoted the highest proliferation and early differentiation. CTNTs scaffolds with FN showed potential as scaffolding material for bone regeneration.","PeriodicalId":15161,"journal":{"name":"Journal of Biomimetics, Biomaterials and Biomedical Engineering","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47491053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Accelerated Variant of an EMD-Based-R Peaks Detection Algorithm Involving FFT-Based Time-Domain Down-Sampling and up-Sampling 基于emd的r峰值检测算法的加速变体，包括基于fft的时域下采样和上采样

IF 0.7

Journal of Biomimetics, Biomaterials and Biomedical Engineering Pub Date : 2023-07-31 DOI: 10.4028/p-E6HyU0

A. Harkat, R. Benzid, N. Athamena

{"title":"Accelerated Variant of an EMD-Based-R Peaks Detection Algorithm Involving FFT-Based Time-Domain Down-Sampling and up-Sampling","authors":"A. Harkat, R. Benzid, N. Athamena","doi":"10.4028/p-E6HyU0","DOIUrl":"https://doi.org/10.4028/p-E6HyU0","url":null,"abstract":"As most of developed empirical mode decomposition (EMD) based R-peaks detection algorithms consume a considerable time of calculation caused by the large length of the input ECG signal, the design of a new technique that allows the acceleration of such methods becomes necessary. Accordingly, a new variant of an EMD-based strategy for R-peaks localization is presented. The new accelerated variant is constituted of three essential parts. The first step is the length reduction of the input signal by means of the truncation in the Fast Fourier Transform (FFT) domain followed by the application of the inverse FFT guaranteeing a suitable time-domain down-sampling. Consequently, the new input signal of a reduced length preserves all medical information contained initially in the original lengthy signal. The second part is dedicated to identify the QRS complex using EMD-based R-peaks detection. This latter comprises a low-pass filter, Empirical Mode Decomposition (EMD) and the Hilbert transform, Finally, the third phase is the time-domain up-sampling using the FFT, the zero padding and the Inverse Fast Fourier Transform (IFFT) to obtain a resulting processed signal which has the same length as the original signal. Next, as a post-processing step, final R-peaks refined localization is achieved. It is noticeable that the new variant ensures same results, in term of accuracy, as the standard method; however, a significant speed-up ratio of 6.95:1 is reported. Additionally, to more prove the effectiveness of the suggested strategy, it has been applied to accelerate two other efficient algorithms and satisfactory speed up ratios of, 7.20:1 and 4.23:1, respectively have been reached.","PeriodicalId":15161,"journal":{"name":"Journal of Biomimetics, Biomaterials and Biomedical Engineering","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43451396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Optimizing Mesh Sizes of Thin Shells Using Biomimicry for a Sustainable Solution 利用仿生学优化薄壳网孔尺寸，寻求可持续解决方案

IF 0.7

Journal of Biomimetics, Biomaterials and Biomedical Engineering Pub Date : 2023-07-31 DOI: 10.4028/p-XYcl3m

Pennarasi Gunasekaran, S. Nachiar, S. Subramanian, A. Sekar

{"title":"Optimizing Mesh Sizes of Thin Shells Using Biomimicry for a Sustainable Solution","authors":"Pennarasi Gunasekaran, S. Nachiar, S. Subramanian, A. Sekar","doi":"10.4028/p-XYcl3m","DOIUrl":"https://doi.org/10.4028/p-XYcl3m","url":null,"abstract":"Nature always has the ability to offer various solutions in day-to-day life of humans in various fields of engineering and science. The term biomimicry refers to the process of adopting solutions from nature to solve complicated problems that refers to analysing the environment for sustainable solutions. This concept is used in various fields of engineering and science. This concept is emerging now in the field of construction also. Biomimics concept is used in analysing the behaviour of structural elements which forms a symbiosis between the environment and construction. In the field of construction, thin shell structures are lightweight structures that are preferred as roof elements for covering high spans and also gives an aesthetic appearance. In this study, three different shapes like spherical with different rise to span ratios, circular and elliptical are considered. The concept of reflecting the human skull shape into thin shell structures was considered, because the reflection from the environment helps in solving the complicated problems of both engineering and sciences. This study focused on the mesh convergence study for numerical analysis using Ansys 18.1 software. The parameters of the thin shells such as thickness, span and rise were taken from the geometrical characteristics of scanned human skull models in comparison with the standard skull models. From the results, mesh sizes were optimized for the three different shapes considered and also predicted the most efficient model. These results were obtained based on the equivalent stress in comparison with the theoretical stresses of the respective models. This study inspires the naturally available forms in the environment to incorporate it in the field of construction and technology for a sustainable solution.","PeriodicalId":15161,"journal":{"name":"Journal of Biomimetics, Biomaterials and Biomedical Engineering","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46070405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Design and Manufacturing a Portable Smart Sole for Measuring the Ground Reaction Force 测量地面反作用力的便携式智能鞋底的设计与制造

IF 0.7

Journal of Biomimetics, Biomaterials and Biomedical Engineering Pub Date : 2023-07-31 DOI: 10.4028/p-mrM7AX

F. M. Kadhim, S. Hasan, Rasha Qasim Humadi

引用次数: 0

Journal of Biomimetics, Biomaterials and Biomedical Engineering Vol. 61 生物仿生学、生物材料和生物医学工程学杂志》第 61 卷

IF 0.7

Journal of Biomimetics, Biomaterials and Biomedical Engineering Pub Date : 2023-07-31 DOI: 10.4028/b-15kwwl

S. Nandyala, David Duday, Kazuo Umemura

引用次数: 0

The Interplay of Brønsted-Lowry and Lewis Acid Sites in Bifunctional Catalyst for the Biomass Conversion to Levulinic Acid Brønsted Lowry和Lewis酸位点在生物质转化为乙酰丙酸的双功能催化剂中的相互作用

IF 0.7

Journal of Biomimetics, Biomaterials and Biomedical Engineering Pub Date : 2023-07-31 DOI: 10.4028/p-RNTv04

Nadiah Syafiqah Mohd Azlan, C. L. Yap, Y. W. Tiong, S. Gan, M. B. A. Rahman

引用次数: 0