Journal of Biomimetics, Biomaterials and Biomedical Engineering最新文献

Analytical Study of Interstitial Fluid Extractive Microneedle Arrays Using Differential Transform Method 基于微分变换的间隙流体萃取微针阵列分析研究

Journal of Biomimetics, Biomaterials and Biomedical Engineering Pub Date : 2023-11-03 DOI: 10.4028/p-2spruh

Ihuoma V. Diwe, Olurotimi A. Adeleye, Henry E. Mgbemere

{"title":"Analytical Study of Interstitial Fluid Extractive Microneedle Arrays Using Differential Transform Method","authors":"Ihuoma V. Diwe, Olurotimi A. Adeleye, Henry E. Mgbemere","doi":"10.4028/p-2spruh","DOIUrl":"https://doi.org/10.4028/p-2spruh","url":null,"abstract":"The computational studies of a predictive mathematical model for the extraction of interstitial (ISF) for transdermal and non-invasive diagnosis using biodegradable and hollow microneedle patch is presented in this paper. Rapid Diagnostic Tests diagnosis, which is non-invasive, affordable, straightforward, and provides results promptly and reliably, has increased access to parasite-based analysis on a global scale. Microneedle arrays are a rapidly evolving and promising technology for transdermal interstitial fluid extraction, which is used for many clinical diagnostic procedures. Hence, a developed mathematical predictive model used to optimize the design of microneedle patch for transdermal ISF extraction and subsequent diagnosis using dissolvable microneedle arrays was applied in this study. The model's solutions were obtained using the Differential Transform Method. The numerical Runge-Kutta method of fourth order was used to validate it. An experimental test result was also used to further validate the analytical results in the absence of the extracted velocity parameter. And there was a good agreement among them. Influence of dissolution rate constant, microneedle height, diffusion coefficient, velocity of ISF, microneedle ISF drug load, and density of the microneedle; were investigated. Increase in diffusion coefficient and density led to an increase in concentration of ISF extracted over time, an increase in dissolution rate led to a decrease in concentration extracted, while decrease in drug load and height, led to increase in ISF concentration extracted. A negligible effect was observed by varying the velocity of ISF extracted. The approximate analytical approach utilized in the current work has given us a more precise strategy for creating a mathematical model that predicts how ISF will be extracted from skin for use in transdermal and non-invasive rapid diagnostic tests.","PeriodicalId":15161,"journal":{"name":"Journal of Biomimetics, Biomaterials and Biomedical Engineering","volume":"41 22","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135819885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Active Rehabilitation Gloves Based on Brain-Computer Interfaces and Deep Learning 基于脑机接口和深度学习的主动康复手套

Journal of Biomimetics, Biomaterials and Biomedical Engineering Pub Date : 2023-11-03 DOI: 10.4028/p-2jc2qf

Jia Hua Zhu, Xing Zhao Shi, Xing Yue Cheng, Qi Rui Yang, Ruo Xiu Xiao

引用次数: 0

In Vitro Study: Bioactivity, Biocompatibility and Antibacterial Behavior for Polyetheretherketone Composites & lt; i&gt Vitro聚醚醚酮复合材料的生物活性、生物相容性及抗菌性能研究

Journal of Biomimetics, Biomaterials and Biomedical Engineering Pub Date : 2023-11-03 DOI: 10.4028/p-2faovi

Alaa A. Mohammed, Emad S. Al-Hassani, Jawad K. Oleiwi

{"title":"In Vitro Study: Bioactivity, Biocompatibility and Antibacterial Behavior for Polyetheretherketone Composites","authors":"Alaa A. Mohammed, Emad S. Al-Hassani, Jawad K. Oleiwi","doi":"10.4028/p-2faovi","DOIUrl":"https://doi.org/10.4028/p-2faovi","url":null,"abstract":"Polyetheretherketone (PEEK) as alternate biomaterial to traditional metallic implant materials has become greater important. At the same time have greater chemical resistance, mechanical properties, biocompatibility and radiolucency, making it convenient for use as dental and orthopedic implants. In the present study the biological behavior was evaluated of polymer composites based polyetheretherketone combined with various nano hydroxyapatite and nano titanium dioxide blending up to (1.5 wt%). The bioactivity of the specimens was evaluated by investigation apatite formation after immersion for 7 days and 14 days in simulated body fluid (SBF). XRD and SEM were used to approve the bioactivity of the specimens. Cell viability, proliferation, and the cell attachment activity of L929 mouse fibroblast cells was evaluated after (1, 3 & 5) days by MTT assay. Antibacterial property of the specimens versus S. aureus was observed with optical density methods. The results detected that the apatite-like layer formation was clearly observed on specimens after immersion for different period in simulated body fluid (SBF). Moreover, Results of MTT assay recorded the PEEK specimens excited the activity of fibroblasts and therefore a high cytocompatibility was noticed and specimens showed antibacterial properties against S. aureus.","PeriodicalId":15161,"journal":{"name":"Journal of Biomimetics, Biomaterials and Biomedical Engineering","volume":"41 19","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135819596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effect of Curcumin on Blood Glucose Patients with Type 2 Diabetes Mellitus: A Systematic Review 姜黄素对2型糖尿病患者血糖的影响:系统综述

Journal of Biomimetics, Biomaterials and Biomedical Engineering Pub Date : 2023-11-03 DOI: 10.4028/p-7ljftp

Nurhasan Agung Prabowo, Yulia Sari, Desy Puspa Putri, Hartono Hartono

{"title":"The Effect of Curcumin on Blood Glucose Patients with Type 2 Diabetes Mellitus: A Systematic Review","authors":"Nurhasan Agung Prabowo, Yulia Sari, Desy Puspa Putri, Hartono Hartono","doi":"10.4028/p-7ljftp","DOIUrl":"https://doi.org/10.4028/p-7ljftp","url":null,"abstract":"Type 2 Diabetes Mellitus (DM) is characterized by elevated blood glucose. Curcumin has glucose-lowering properties. This review intended to determine if Curcumin can lower blood glucose levels in type 2 diabetic patients. This review intended to determine if Curcumin can decrease blood glucose in type 2 DM patients. Curcumin has a mechanism of stimulating incretin and inhibiting digestive enzymes from reducing blood glucose levels in type 2 DM patients. We systematically searched PubMed for peer-reviewed studies examining the mechanism of Curcumin in decreasing blood glucose in type 2 DM patients. The journal criteria included in this review were a study from 2000 to 2022, randomized control trial using intervention Curcumin, an outcome variable using blood glucose, the full text of the article can be obtained, and the DM patient's age is over 18 years. Two independent reviewers retrieved data o clinical outcomes, studies, and patient characteristics using the Cochrane Risk of Bias Assessment Instrument. Quality is evaluated using the Grading of Recommendations Assessment, Development, and Evaluation system. There are 19 studies included in this research, and Three journals meet the requirements. The conclusion is that curcumin can decrease blood glucose in Type 2 DM patients.","PeriodicalId":15161,"journal":{"name":"Journal of Biomimetics, Biomaterials and Biomedical Engineering","volume":"42 15","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135819877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Journal of Biomimetics, Biomaterials and Biomedical Engineering Vol. 63 生物仿生学、生物材料和生物医学工程学杂志》第 63 卷

IF 0.7

Journal of Biomimetics, Biomaterials and Biomedical Engineering Pub Date : 2023-11-03 DOI: 10.4028/b-q6rjge

David Duday, S. Nandyala, A. Shidiq, Thangaprakash Sengodan

引用次数: 0

Synthesis of Colloidal Silver Nanoparticles Using Alginate as Reducing and Stabilizing Agents and its Application as Antibacterial Material 以海藻酸盐为还原剂和稳定剂合成纳米银胶体及其抗菌材料的研究

Journal of Biomimetics, Biomaterials and Biomedical Engineering Pub Date : 2023-11-03 DOI: 10.4028/p-reri3h

Endang Susilowati, Lina Mahardiani, Sri Retno Dwi Ariani, Hidayat Fauzi

{"title":"Synthesis of Colloidal Silver Nanoparticles Using Alginate as Reducing and Stabilizing Agents and its Application as Antibacterial Material","authors":"Endang Susilowati, Lina Mahardiani, Sri Retno Dwi Ariani, Hidayat Fauzi","doi":"10.4028/p-reri3h","DOIUrl":"https://doi.org/10.4028/p-reri3h","url":null,"abstract":"Synthesis of colloidal silver nanoparticles has been successfully conducted through the chemical reduction technique. The synthesis used AgNO3, NaOH, and alginate as the precursor, accelerator reagent, and reducing agent and stabilizer, respectively. The effects of heating temperature, reaction time, accelerator concentration, and precursor concentration were investigated according to the localized surface plasmon resonance (LSPR) phenomenon using a UV-Vis spectrophotometer. The nanoparticle size distribution was observed via a Particle Size Analyzer (PSA). The stability of silver nanoparticles was studied for 8 weeks based on the LSPR phenomenon. Then, their antibacterial performance toward S. Aureus ATCC 25923 and E. Coli ATCC 25922 was examined. The results showed the absorbance intensities representing the number of silver nanoparticles formed were influenced by temperature, reaction time, NaOH concentration, and AgNO3 concentration. At 50°C heating, the optimum synthesis of silver nanoparticles was achieved at 50 min with a NaOH concentration of 0.013M. The higher AgNO3 concentration resulted in a greater concentration of silver nanoparticles produced. From the PSA characterization, the average particle sizes for the samples were 1.82 nm and 1.30 nm for AgNO3 concentrations (% w/w; AgNO3/Alginate) of 1.6% and 2.4%, respectively. Based on the LSPR phenomenon, colloidal silver nanoparticles were stable in storage for 8 weeks at room temperature. The increase in the concentration of silver nanoparticles within colloidal could enhance antibacterial performance against S. Aureus and E. Coli. Accordingly, silver nanoparticles synthesized with alginate as a stabilizer have the potential as an antibacterial compound for medical applications.","PeriodicalId":15161,"journal":{"name":"Journal of Biomimetics, Biomaterials and Biomedical Engineering","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135819605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Public Perception of the Chemical Composition of Covid-19 Vaccine that Hinders the Implementations of COVID-19 Vaccination in Indonesia 公众对Covid-19疫苗化学成分的认知阻碍了Covid-19疫苗在印度尼西亚的实施

Journal of Biomimetics, Biomaterials and Biomedical Engineering Pub Date : 2023-11-03 DOI: 10.4028/p-b6jawk

Tonang Dwi Ardyanto, Nurhasan Agung Prabowo, Risalina Myrtha, Laaily Shofiyah

{"title":"Public Perception of the Chemical Composition of Covid-19 Vaccine that Hinders the Implementations of COVID-19 Vaccination in Indonesia","authors":"Tonang Dwi Ardyanto, Nurhasan Agung Prabowo, Risalina Myrtha, Laaily Shofiyah","doi":"10.4028/p-b6jawk","DOIUrl":"https://doi.org/10.4028/p-b6jawk","url":null,"abstract":"Indonesia has been facing COVID-19 since March 2020, causing significant problems for public health. Indonesia is trying to solve this problem, and the vaccination program began in January 2021. Several obstacles include public acceptance of the composition of the COVID-19 vaccine. We systematically searched peer-reviewed studies during 2020-2022, examining analyses of the Chemical Composition of the COVID-19 Vaccine authorized in Indonesia. We also explored the related information from the official body. Finally, we constructed a short review of the public acceptance of the vaccine focusing on the chemical composition. All COVID-19 vaccines are intended to induce humoral and cellular immunity toward infection. The antigen causes this as an active ingredient of the vaccine. The vaccine also contains adjuvants, and some other chemicals are required. The expansion aims to maintain the content of the vaccine, strengthen the body's reaction to the vaccine, and facilitate the administration process. But there are concerns about the risk of unintended effects of the substances used. This perception includes those that hinder the implementation of COVID-19 Vaccination in Indonesia. There is a need to disseminate information and education about the vaccine composition so that the optimal vaccination program benefits the community.","PeriodicalId":15161,"journal":{"name":"Journal of Biomimetics, Biomaterials and Biomedical Engineering","volume":"40 21","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135819608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Utilize Chitosan to Coat Hydroxyapatite on Polymer 壳聚糖在聚合物表面涂覆羟基磷灰石的研究

Journal of Biomimetics, Biomaterials and Biomedical Engineering Pub Date : 2023-11-03 DOI: 10.4028/p-k17meg

Marwa Jamal Mohammed, Marwan N. Arbilei, Sadiq J. Hamandi, Hussein A. Hussein

{"title":"Utilize Chitosan to Coat Hydroxyapatite on Polymer","authors":"Marwa Jamal Mohammed, Marwan N. Arbilei, Sadiq J. Hamandi, Hussein A. Hussein","doi":"10.4028/p-k17meg","DOIUrl":"https://doi.org/10.4028/p-k17meg","url":null,"abstract":"Biocompatible bone implants are often proposed to improve osseointegration such as metal or polymer. Calcium hydroxyapatite Ca 10 (PO 4 ) 6 -OH 2 , HA is the primary inorganic component of human bone. Hydroxyapatite and polymer are biocompatible to the human body and help to increase bone growth. Increasing osseointegration by application of coating polymer on ceramic using the dip coating method is a challenge in itself for the success of the process of coating polymeric materials on ceramic materials using the previous method. This research aims to establish a new interface for promoting osseointegration. This interface between the polymeric part and the bone tissue to overcome the problems and failures that occur in the metal limbs implanted in the amputees. As a result of its rejection by the cells of the living body or the lack of good cohesion between the implant and the place of contact. In this work, coat PEEK plastic material coated with an active biocompatible material (Hydroxyapatite). The polymeric parts that implant inside the bone will be used as an anchor for the metallic screw that is used for bone succession or artificial limb. This research is one of a series of investigations that enhance bone osseointegration in the simplest and most efficient method. The dipping method is used to create adhesive between ceramic and polymer (polyether ether ketone) depending on the chitosan material. Tape tests showed that there was good adherence between the HA and PEEK surfaces.","PeriodicalId":15161,"journal":{"name":"Journal of Biomimetics, Biomaterials and Biomedical Engineering","volume":"41 22","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135819736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of Plant Oil Derived Bio-Resin and Curing Temperature on Static and Dynamic Mechanical Properties of Epoxy Network 植物油衍生生物树脂及固化温度对环氧树脂网静态和动态力学性能的影响

Journal of Biomimetics, Biomaterials and Biomedical Engineering Pub Date : 2023-11-03 DOI: 10.4028/p-ui9jks

Sekar Kannan, Sathyaraj Sankar Lal

引用次数: 0

The Fragility of Glassy Corn Starches 透明玉米淀粉的脆弱性

Journal of Biomimetics, Biomaterials and Biomedical Engineering Pub Date : 2023-11-03 DOI: 10.4028/p-c4ncik

Vaibhavi H. Mistry, Niravkumar D. Patel, T. Lilly Shanker Rao, Toluchuri Shanker Rao

引用次数: 0