Journal of Biomimetics, Biomaterials and Biomedical Engineering最新文献_第4页

Optimizing Mesh Sizes of Thin Shells Using Biomimicry for a Sustainable Solution 利用仿生学优化薄壳网孔尺寸，寻求可持续解决方案

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Journal of Biomimetics, Biomaterials and Biomedical Engineering Pub Date : 2023-07-31 DOI: 10.4028/p-XYcl3m

Pennarasi Gunasekaran, S. Nachiar, S. Subramanian, A. Sekar

{"title":"Optimizing Mesh Sizes of Thin Shells Using Biomimicry for a Sustainable Solution","authors":"Pennarasi Gunasekaran, S. Nachiar, S. Subramanian, A. Sekar","doi":"10.4028/p-XYcl3m","DOIUrl":"https://doi.org/10.4028/p-XYcl3m","url":null,"abstract":"Nature always has the ability to offer various solutions in day-to-day life of humans in various fields of engineering and science. The term biomimicry refers to the process of adopting solutions from nature to solve complicated problems that refers to analysing the environment for sustainable solutions. This concept is used in various fields of engineering and science. This concept is emerging now in the field of construction also. Biomimics concept is used in analysing the behaviour of structural elements which forms a symbiosis between the environment and construction. In the field of construction, thin shell structures are lightweight structures that are preferred as roof elements for covering high spans and also gives an aesthetic appearance. In this study, three different shapes like spherical with different rise to span ratios, circular and elliptical are considered. The concept of reflecting the human skull shape into thin shell structures was considered, because the reflection from the environment helps in solving the complicated problems of both engineering and sciences. This study focused on the mesh convergence study for numerical analysis using Ansys 18.1 software. The parameters of the thin shells such as thickness, span and rise were taken from the geometrical characteristics of scanned human skull models in comparison with the standard skull models. From the results, mesh sizes were optimized for the three different shapes considered and also predicted the most efficient model. These results were obtained based on the equivalent stress in comparison with the theoretical stresses of the respective models. This study inspires the naturally available forms in the environment to incorporate it in the field of construction and technology for a sustainable solution.","PeriodicalId":15161,"journal":{"name":"Journal of Biomimetics, Biomaterials and Biomedical Engineering","volume":"61 1","pages":"1 - 14"},"PeriodicalIF":0.7,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46070405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Journal of Biomimetics, Biomaterials and Biomedical Engineering Vol. 61 生物仿生学、生物材料和生物医学工程学杂志》第 61 卷

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Journal of Biomimetics, Biomaterials and Biomedical Engineering Pub Date : 2023-07-31 DOI: 10.4028/b-15kwwl

S. Nandyala, David Duday, Kazuo Umemura

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The Interplay of Brønsted-Lowry and Lewis Acid Sites in Bifunctional Catalyst for the Biomass Conversion to Levulinic Acid Brønsted Lowry和Lewis酸位点在生物质转化为乙酰丙酸的双功能催化剂中的相互作用

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Journal of Biomimetics, Biomaterials and Biomedical Engineering Pub Date : 2023-07-31 DOI: 10.4028/p-RNTv04

Nadiah Syafiqah Mohd Azlan, C. L. Yap, Y. W. Tiong, S. Gan, M. B. A. Rahman

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Antibacterial Effect of Experimental Orthodontic Elastomeric Ligature Coated with Zinc Oxide Particles 氧化锌颗粒涂层正畸弹性体扎带的抗菌效果

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Journal of Biomimetics, Biomaterials and Biomedical Engineering Pub Date : 2023-07-31 DOI: 10.4028/p-QCM4oh

Kornkanok Khlongwanitchakul, N. Anuwongnukroh, S. Dechkunakorn, Parichart Naruphontjirakul, W. Wichai, R. Srisatjaluk

{"title":"Antibacterial Effect of Experimental Orthodontic Elastomeric Ligature Coated with Zinc Oxide Particles","authors":"Kornkanok Khlongwanitchakul, N. Anuwongnukroh, S. Dechkunakorn, Parichart Naruphontjirakul, W. Wichai, R. Srisatjaluk","doi":"10.4028/p-QCM4oh","DOIUrl":"https://doi.org/10.4028/p-QCM4oh","url":null,"abstract":"Objectives . This study aimed to evaluate antibacterial activity of elastomeric ligatures coated with Zinc oxide particles against Streptococcus mutans. Methods. ZnO particles grafted with (3-Aminopropyl) trimethoxysilane (APTMS) were prepared in situ. The ATR-FTIR spectrum was used to analyze the APTMS grafted on ZnO surfaces. Two concentrations of ZnO-APTMS, i.e., 5 and 10 wt%, were coated on orthodontic elastomeric ligatures by the dip coating method. Antibacterial property of the ZnO-APTMS coated elastomeric ligatures against S. mutans ATCC25175 were investigated by the agar diffusion test. The effect of ligature aging on antibacterial property was evaluated by the direct contact test, in which the growth of bacteria was determined by the turbidity after exposed to the samples that had been immersed in distilled water for 0, 3, 7, 14, 28 days. The drop plate test was also performed to determine the inhibitory and the bactericidal effects. Results. The analysis of ATR-FTIR spectrum confirmed that APTMS was successfully grafted on ZnO surfaces. The agar diffusion test could not demonstrate the antimicrobial effects of the ZnO-coated elastomeric ligatures. However, results from the direct contact and the drop plate tests showed the inhibitory effects on bacterial growth compared to the positive controls (p < 0.05). The inhibitory effect of the ZnO-coated elastomeric ligatures was observed even after they had been immersed in distilled water for 28 days. Conclusions. The surface coating elastomeric ligatures with 5 and 10 wt% ZnO-APTMS exhibited antibacterial activity against cariogenic bacteria, S. mutans. The bacterial inhibitory effect was prolonged until 28-day.","PeriodicalId":15161,"journal":{"name":"Journal of Biomimetics, Biomaterials and Biomedical Engineering","volume":"61 1","pages":"43 - 50"},"PeriodicalIF":0.7,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48815698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Investigating the Electrochemical Properties of Alkaloids Compound Derived from Catharanthus Roseus Extract 花楸花提取物生物碱类化合物的电化学性质研究

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Journal of Biomimetics, Biomaterials and Biomedical Engineering Pub Date : 2023-07-31 DOI: 10.4028/p-yBmV9q

Marwah Al-Azzawi, W. R. Saleh

{"title":"Investigating the Electrochemical Properties of Alkaloids Compound Derived from Catharanthus Roseus Extract","authors":"Marwah Al-Azzawi, W. R. Saleh","doi":"10.4028/p-yBmV9q","DOIUrl":"https://doi.org/10.4028/p-yBmV9q","url":null,"abstract":"The Catharanthus roseus plant was extracted and converted to nanoparticles in this work. The Soxhlet method was used to extract alkaloid compounds from the Catharanthus roseus plant and converted them to the nanoscale. Chitosan polymer was used as a linking material and converted to Chitosan nanoparticles (CSNPs). The extracted alkaloids were linked with Chitosan nanoparticles by maleic anhydride to get the final product (CSNPs-Linker-alkaloids). The pure Chitosan, Chitosan nanoparticles, and CSNPs-Linker-alkaloids were characterized by X-ray diffractometer, and Fourier Transform Infrared spectroscopy. X-ray results show that all samples have an orthorhombic structure with crystallite size in nanodimensions. FTIR spectra prove that the P=O is the cross-linkage between chitosan and phosphate groups by ionic bond, which indicate that the Chitosan nanoparticle has been formed in the solution. FTIR spectrum for CSNPs - Linker - alkaloids appear a new distinct band at 1708.93 cm-1 which demonstrates the presence of C = O esterification. Atomic Force Microscope images of the Chitosan nanoparticles and CSNPs-Linker-alkaloids show that they have almost spherical shapes with average sizes of 90 and 92.6 nm respectively. The electroactive surface area of glassy carbon electrodes (GCE), extract plant, and Linker-alkaloids were calculated in KCl solution containing K3[Fe (CN)6]. The presence of CSNPs-Linker-alkaloids in modified glassy carbon electrodes about 3 times. The successful synthesis of organic nanoparticles from the Catharanthus roseus plant can be used safely in biosensors, environmental monitoring, and biomedical applications.","PeriodicalId":15161,"journal":{"name":"Journal of Biomimetics, Biomaterials and Biomedical Engineering","volume":"61 1","pages":"93 - 107"},"PeriodicalIF":0.7,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43734108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Electrophoretic Deposition of Nanohydroxyapatite on Homogenized Magnesium Based Alloy for Biomedical Applications 电泳沉积纳米羟基磷灰石在均匀化镁基合金上的生物医学应用

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Journal of Biomimetics, Biomaterials and Biomedical Engineering Pub Date : 2023-07-31 DOI: 10.4028/p-CU9Y6h

T. O. Sadiq, I. Sudin, Ahmed Alsakkaf, J. Idris, N. A. Fadil

{"title":"Electrophoretic Deposition of Nanohydroxyapatite on Homogenized Magnesium Based Alloy for Biomedical Applications","authors":"T. O. Sadiq, I. Sudin, Ahmed Alsakkaf, J. Idris, N. A. Fadil","doi":"10.4028/p-CU9Y6h","DOIUrl":"https://doi.org/10.4028/p-CU9Y6h","url":null,"abstract":"Magnesium (Mg) alloys are promising biodegradable implant materials. If successful, they do not require second surgical operation for their removal. However, the focus of this study is to address the limitation of fast degradation rate (DR) which hinders the clinical application of Mg alloys. The bio-corrosion rate of any intermetallic alloy is related to its beta (β) phase volume fraction. Thus, homogenization heat treatment (HHT) was carried out to reduce the β phase. The influence of β phase and the hydroxyapatite powders (HAp) was employed to slow down the initial DR of Mg AZ91 alloy. Samples were cut from Mg grade AZ91 alloy ingot in 10mm x 10mm x 3mm dimension. The samples were prepared and divided into two; the first part was classified as as-received sample (sample a) while the second one was processed for HHT. HHT was carried out at 410°C/10h, cooled inside the furnace and named as homogenized sample (sample b). The HAp was synthesized using a simple wet chemical precipitation technique (SWCPT) and deposited on sample b via electrophoretic deposition (EPD) at different voltages with different deposition times. The HAp, uncoated and coated samples were characterized. Potentiodynamic polarization (PP) and immersion tests were carried out in stimulated body fluid (SBF) to estimate the DR and in vitro bioactivity of Mg AZ91 respectively. The results revealed a significant drop in DR from sample a (1.421 mm per year) to coated sample h (3.73 x 10-4 mm per year). Keywords: Magnesium alloy, biodegradable implants, beta phase, homogenization heat treatment, hydroxyapatite, electrophoretic deposition.","PeriodicalId":15161,"journal":{"name":"Journal of Biomimetics, Biomaterials and Biomedical Engineering","volume":"61 1","pages":"15 - 41"},"PeriodicalIF":0.7,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43189866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Premature Ventricular Contraction (PVC) Recognition Using DCT-CWT Based Discriminant and Optimized RBF Neural Network 基于DCT-CWT的判别优化RBF神经网络识别室性早搏

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Journal of Biomimetics, Biomaterials and Biomedical Engineering Pub Date : 2023-05-31 DOI: 10.4028/p-6yc34j

A. Harkat, R. Benzid

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Zeolitic Imidazolate Framework-8-Loaded Hydrogels as a Highly Biocompatible Carrier for Drug Delivery Applications 沸石咪唑骨架-8-负载水凝胶作为药物递送应用的高度生物相容性载体

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Journal of Biomimetics, Biomaterials and Biomedical Engineering Pub Date : 2023-05-31 DOI: 10.4028/p-268hc7

Pagasukon Mekrattanachai, Naruemon Setthaya, Chakkresit Chindawong, Bunlawee Yotnoi, W.-G. Song, Natchanon Ratanapun, Supreeda Tambunlertchai, C. Manaspon

{"title":"Zeolitic Imidazolate Framework-8-Loaded Hydrogels as a Highly Biocompatible Carrier for Drug Delivery Applications","authors":"Pagasukon Mekrattanachai, Naruemon Setthaya, Chakkresit Chindawong, Bunlawee Yotnoi, W.-G. Song, Natchanon Ratanapun, Supreeda Tambunlertchai, C. Manaspon","doi":"10.4028/p-268hc7","DOIUrl":"https://doi.org/10.4028/p-268hc7","url":null,"abstract":"Zeolitic imidazolate frameworks-8 (ZIF-8), a type of metal-organic frameworks (MOFs), displays high porosity, large surface areas, and tunable functionality in nanocomposites, promising carrier for drug delivery applications. In this work, ZIF-8 nanomaterials were synthesized via precipitation under three different conditions and subsequently loaded onto chitosan/pluronic F-127 (CS/PL) hydrogels. The ZIF-8 materials prepared in NH4OH solution (ZIF-8-NH4OH) showed a regular cubic shape with a large particle size of approximately 963 nm due to the acceleration of crystal growth in a basic medium. Meanwhile, the ZIF-8 species prepared in H2O and MeOH (ZIF-8-H2O and ZIF-8-MeOH, respectively) displayed crystal sizes of approximately 152 and 240 nm, respectively. The overall toxicity of the ZIF-8 nanomaterials was determined with an XTT assay against the L929 mouse fibroblast cell line. The morphology of the cells was altered at a concentration of over 30 µg/mL due to cell membrane deformations. This result correlated with the lactate dehydrogenase (LDH) release study by detection of LDH release at a concentration of over 25 µg/mL (50% LDH release). To reduce the toxicity of the ZIF-8 materials, CS/PL hydrogels were appropriately prepared and used to encapsulate the ZIF-8 at 0.095% w/w. Cytotoxicity results of the ZIF-8-loaded CS/PL hydrogels indicated over 75% cell viability of the L929 cells. These results presented significant implications for future applications of the ZIF-8 particles in the delivery of drugs or other compounds.","PeriodicalId":15161,"journal":{"name":"Journal of Biomimetics, Biomaterials and Biomedical Engineering","volume":"60 1","pages":"29 - 42"},"PeriodicalIF":0.7,"publicationDate":"2023-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41788020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Development and Characterization of Nanovesicles Containing Phenolic Compounds of Carissa spinarum: Encapsulation, Release Kinetics, Antimicrobial Activity and Mathematical Modeling 棘豆酚类化合物纳米囊泡的制备与表征:包封、释放动力学、抗菌活性和数学模型

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Journal of Biomimetics, Biomaterials and Biomedical Engineering Pub Date : 2023-05-31 DOI: 10.4028/p-8mzn1a

Clarence Rubaka, J. Gathirwa, H. Malebo, H. Swai, A. Hilonga

{"title":"Development and Characterization of Nanovesicles Containing Phenolic Compounds of Carissa spinarum: Encapsulation, Release Kinetics, Antimicrobial Activity and Mathematical Modeling","authors":"Clarence Rubaka, J. Gathirwa, H. Malebo, H. Swai, A. Hilonga","doi":"10.4028/p-8mzn1a","DOIUrl":"https://doi.org/10.4028/p-8mzn1a","url":null,"abstract":"The aim of this study was to develop and characterize a delivery system for polyphenols from an extract of Carissa spinarum leaves, based on liposomes. Liposomes loaded with Carissa spinarum polyphenols (nanoliposomal CsP) were prepared by ethanol-solvent injection method and characterized in terms of zeta potential, size, and polydipersity index by using Zeta sizer and Fourier Transform Infrared spectrum analysis. Total Phenolic content was measured by using Folin-Ciocalteu method and entrapment efficiency was evaluated. The release behavior was conducted in Phosphate Buffer Saline (PBS) solution at pH, 7.4 and Kinetic model fitted to evaluate mechanism of release. Disc diffusion sensitivity test was used to evaluate antimicrobial activity of free extract and nanoliposomal CsP. The mean diameter of nanoliposomal CsP was 181 ± 1.02 nm and had 0.345 ± 0.014 polydipersity index. Zeta potential value for nanoliposomal CsP was-45.6 ± 8.84 mV. Entrapment efficiency under the optimum conditions was 66.11 ± 1.11%. and the nanoliposomal CsP was stable over 30 days. The antibacterial activity of nanoliposomal CsP exhibited inhibition zone diameter of 14.33 ± 1.53 mm and 12.00 ± 1.23 mm against S. aureus and E. coli respectively The results reveal the Carrisa spinarum liposome can be applied as potential carrier for delivery of polyphenols to improves therapeutic action against bacterial strain.","PeriodicalId":15161,"journal":{"name":"Journal of Biomimetics, Biomaterials and Biomedical Engineering","volume":"60 1","pages":"43 - 52"},"PeriodicalIF":0.7,"publicationDate":"2023-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45959326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Numerical Modeling of the Capsular Ligament Failure for the C2-C3 Segment in the Case of a Frontal Impact 正面碰撞时C2-C3节段囊韧带损伤的数值模拟

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Journal of Biomimetics, Biomaterials and Biomedical Engineering Pub Date : 2023-05-31 DOI: 10.4028/p-3td39z

N. Damba, B. Aour, A. Oudrane, Lamsadfa Sidamar

{"title":"Numerical Modeling of the Capsular Ligament Failure for the C2-C3 Segment in the Case of a Frontal Impact","authors":"N. Damba, B. Aour, A. Oudrane, Lamsadfa Sidamar","doi":"10.4028/p-3td39z","DOIUrl":"https://doi.org/10.4028/p-3td39z","url":null,"abstract":"The cervical spine is a complex anatomical structure that mainly stabilizes the head and protects the spinal cord. Injuries of the cervical spine often occur during falls or road accidents and are particularly serious since they generate strong threats of paralysis and death. It should be noted that the ligaments provide cervical stability but their stabilization in case of injury is not yet well investigated. In this context, the objective of the present work is to study the failure of the ligaments by developing a bio-faithful numerical model while using a more realistic geometry of the spinal components and behavior laws that take into account the effect of strain rate and motion amplitudes. In order to validate the results of the study, we conducted a comparison with previous literature studies. It has been found that damage is often supported by intervertebral discs, anterior longitudinal ligaments (ALL) and capsular ligaments (CL) in the case of frontal impact. Indeed, the highest stresses are concentrated in the annulus fibrosus and the capsular ligaments. In this study, we tested the effect of ligament tears on disc behavior, where it was found that the stress rate increased by approximately 6%. The effect of capsular ligament tear orientation was also examined. The obtained results show that the most dangerous inclination was downward at an angle of 45°.","PeriodicalId":15161,"journal":{"name":"Journal of Biomimetics, Biomaterials and Biomedical Engineering","volume":"60 1","pages":"69 - 81"},"PeriodicalIF":0.7,"publicationDate":"2023-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42964771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0