Journal of Biomimetics, Biomaterials and Biomedical Engineering最新文献_第3页

Journal of Biomimetics, Biomaterials and Biomedical Engineering Vol. 62 生物仿生学、生物材料和生物医学工程学杂志》第 62 卷

IF 0.7

Journal of Biomimetics, Biomaterials and Biomedical Engineering Pub Date : 2023-10-24 DOI: 10.4028/b-l1hbsy

A. Shidiq, Steven Y. Liang, M. Kaloop

引用次数: 0

Physicochemical and Characterization Nano-Calcium Catfish Bone Flour (Clarias gariepinus) 纳米钙鲶鱼骨粉(Clarias gariepinus)

Journal of Biomimetics, Biomaterials and Biomedical Engineering Pub Date : 2023-10-24 DOI: 10.4028/p-e0djpd

Siti Suryaningsih, Buchori Muslim, Mohamad Djali

{"title":"Physicochemical and Characterization Nano-Calcium Catfish Bone Flour (Clarias gariepinus)","authors":"Siti Suryaningsih, Buchori Muslim, Mohamad Djali","doi":"10.4028/p-e0djpd","DOIUrl":"https://doi.org/10.4028/p-e0djpd","url":null,"abstract":"The aim of the study was to determine the physicochemical and characterization of nano-calcium Catfish bone flour. The research implementation consisted of several stages: Preparation of fish bone meal, chemical characterization, physical characterization. The t test was used to see differences in treatment. The results of the research: chemical analysis of nano-calcium catfish bone flour revealed that it had a water content of 7.45%, ash 63.29%, protein 4.50%, lipid 2.95%, and carbohydrate 21.81%. Furthermore, both 33.15% calcined bone meal and the 32.16% non-calcined bone meal have calcium contents that meet the Quality I criterion. The findings of the physical characteristics test show nanoparticles in the uncalcined bone meal particle size, which is based on the percent number of 204.1 nm achieved with PI (degree of non-uniformity of particle distribution 0.403). And the calcined bone flour indicated the presence of nanoparticles and that their distribution tended to be uniform, with intensity percentages of 675.4 nm (86.1%) and 100.7 nm (13.9%), respectively. Visually, calcined nano-calcium flour is whiter in color than non-calcined nano-calcium flour. The advantages of alternative research for natural nanocalcium sources from catfish bone meal can be employed in food product manufacturing to satisfy the body's calcium requirements","PeriodicalId":15161,"journal":{"name":"Journal of Biomimetics, Biomaterials and Biomedical Engineering","volume":"20 7","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135267060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Viability Base Gel as Potential for Fabricating Crassostrea gigas hydroxyapatite (HA-Crassostrea gigas shell) Gel for Dental Caries Repair 活力基凝胶制备长牡蛎羟基磷灰石</i&gt(HA-长牡蛎壳)龋齿修复凝胶

Journal of Biomimetics, Biomaterials and Biomedical Engineering Pub Date : 2023-10-24 DOI: 10.4028/p-ly1ksh

Aminatun Nisa, Mona Sari, Yusril Yusuf

{"title":"Viability Base Gel as Potential for Fabricating Crassostrea gigas hydroxyapatite (HA-Crassostrea gigas shell) Gel for Dental Caries Repair","authors":"Aminatun Nisa, Mona Sari, Yusril Yusuf","doi":"10.4028/p-ly1ksh","DOIUrl":"https://doi.org/10.4028/p-ly1ksh","url":null,"abstract":"This study aims to create a gel base composition that has the potential to be combined with hydroxyapatite from the biogenic material Crassostrea gigas as a gel that can repair dental caries. The base gel composition consists of Na-CMC, guar gum, and glycerin which can dissolve the HA element without settling so that it can be applied well to the teeth. nano HA contained in Crassostrea gigas can potentially remineralize and improve caries in teeth. Therefore, it is inevitable that the base gel is safe to make composites with nano HA as a function of repairing dental caries. The potential of HA as a tooth remineralization material was proven by the SEM, FTIR, and XRD characterization of CaCO 3 and CaO, which have sharp crystallinity. The base gel is safe to be applied to the bones of the teeth by the MTT test treatment. This proves that the base gel is not toxic and has high viability of 92.66% at a dose of 31.25 μg/mL. The IC50 value was 688.6 μg/ml. These results are safe to be applied with nano HA material and are safe to be applied to the bones of the teeth.","PeriodicalId":15161,"journal":{"name":"Journal of Biomimetics, Biomaterials and Biomedical Engineering","volume":"1 4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135267877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of Newly Formulated Chlorhexidine Mouthwash 新配方洗必泰漱口水的评价

Journal of Biomimetics, Biomaterials and Biomedical Engineering Pub Date : 2023-10-24 DOI: 10.4028/p-dppua9

Peerapong Tua-Ngam, Ratchaporn Srichan, Arthit Klaophimai, Pachara Rudrakanjana, Thanattha Wuttihasa, Rattiporn Kaypetch

引用次数: 0

Scaffold of Bone Tissue Engineering Based on PVA/BCP Bioactive Composite Foam 基于PVA/BCP生物活性复合泡沫的骨组织工程支架

IF 0.7

Journal of Biomimetics, Biomaterials and Biomedical Engineering Pub Date : 2023-07-31 DOI: 10.4028/p-xBhp5F

F. Hashim, Wafaa A. Hussain, M. Ismail, Ahmed Amr, Abdulqadher M. Daham, Luay H. Alwan

{"title":"Scaffold of Bone Tissue Engineering Based on PVA/BCP Bioactive Composite Foam","authors":"F. Hashim, Wafaa A. Hussain, M. Ismail, Ahmed Amr, Abdulqadher M. Daham, Luay H. Alwan","doi":"10.4028/p-xBhp5F","DOIUrl":"https://doi.org/10.4028/p-xBhp5F","url":null,"abstract":"This study constructed poly (vinyl alcohol)/ biphasic-calcium phosphate (PVA/ BCP) composite scaffolds. The biphasic-calcium phosphate (BCP) was incorporated in 0, 5, 10, and 25 wt%; BP0, BP1, BP2, and BP3, respectively. The surface morphology was done with a scanning electron microscope (SEM) to observe the porosity and the pore size and distribution of fabricated samples. The Fourier Transform Infrared spectroscopy (FTIR), and some physical properties such as porosity, density, swelling ratio, flexural strength, impact strength, and compression strength were also investigated. The biodegradation and bioactivity were also tested. The SEM results showed that the pores increased and became more regular and interconnected to each other with the increasing addition of BCP. The density decreased with the addition of BCP, while the porosity and mechanical properties increased with additives. The sample of BP3 has a high porosity (67%) and high impact strength (11.9 MPa). The high porosity is favorable for bone implants, and the mechanical strength must also be considered. The bio tests show that the biodegradation became regular by adding the BCP powder, which leads to ease of controlling the gradual degradation and the samples are bioactive for bone tissue. Keywords: Bone Tissue Engineering, PVA, Biphasic-Calcium Phosphate, Porosity, Mechanical properties","PeriodicalId":15161,"journal":{"name":"Journal of Biomimetics, Biomaterials and Biomedical Engineering","volume":"61 1","pages":"59 - 70"},"PeriodicalIF":0.7,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47679507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

LLDPE/TiO2-ZnO Nanocomposite Films induces Transitory Oxidative Stress Response on Human Fibroblast and Blood Cell Lines Models LLDPE/TiO2-ZnO纳米复合膜诱导人成纤维细胞和血细胞模型的瞬态氧化应激反应

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Journal of Biomimetics, Biomaterials and Biomedical Engineering Pub Date : 2023-07-31 DOI: 10.4028/p-2aa27K

Nor Hazliana Harun, R. Mydin, S. Sreekantan, Khairul Arifah Saharuddin, A. Seeni

{"title":"LLDPE/TiO2-ZnO Nanocomposite Films induces Transitory Oxidative Stress Response on Human Fibroblast and Blood Cell Lines Models","authors":"Nor Hazliana Harun, R. Mydin, S. Sreekantan, Khairul Arifah Saharuddin, A. Seeni","doi":"10.4028/p-2aa27K","DOIUrl":"https://doi.org/10.4028/p-2aa27K","url":null,"abstract":"Healthcare-associated infections (HAIs) are a major safety concern globally that contribute to mortality rates amongst patients especially associated with indwelling or implanted medical devices. The advanced metal-oxide nanocomposites (MNPs) embedded in polymer matrix present an outstanding antibacterial profile, especially for MDR strains owing to reactive oxygen species (ROS) and free radicals’ mode of action. To date, there is still a lack of knowledge on the implication of external reactive species from MNPs-based polymers to humans. This study investigates the bio-interaction of TiO2-ZnO nanocomposite films embedded in linear low-density polyethylene (LLDPE/ TiO2-ZnO) on human fibroblast and blood cell lines model at molecular genes and protein level. The initial analysis of the in vitro bio-interaction responses on fibroblast and blood cell line models showed signs of cell membrane integrity disturbance, which might be due to free radicals’ activities, such as the release of intracellular ROS and Zn ions (Zn2+) during the initial cellular adaptation process on the TiO2–ZnO polymer nanocomposite film. Further findings found that cell–polymer nanocomposite film interaction could possibly trigger transitory oxidative stress response and cellular redox regulation via NF-kβ interactions. However, further comprehensive studies are needed to support this study, especially involving animal models.","PeriodicalId":15161,"journal":{"name":"Journal of Biomimetics, Biomaterials and Biomedical Engineering","volume":"61 1","pages":"77 - 91"},"PeriodicalIF":0.7,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45990774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Accelerated Variant of an EMD-Based-R Peaks Detection Algorithm Involving FFT-Based Time-Domain Down-Sampling and up-Sampling 基于emd的r峰值检测算法的加速变体，包括基于fft的时域下采样和上采样

IF 0.7

Journal of Biomimetics, Biomaterials and Biomedical Engineering Pub Date : 2023-07-31 DOI: 10.4028/p-E6HyU0

A. Harkat, R. Benzid, N. Athamena

{"title":"Accelerated Variant of an EMD-Based-R Peaks Detection Algorithm Involving FFT-Based Time-Domain Down-Sampling and up-Sampling","authors":"A. Harkat, R. Benzid, N. Athamena","doi":"10.4028/p-E6HyU0","DOIUrl":"https://doi.org/10.4028/p-E6HyU0","url":null,"abstract":"As most of developed empirical mode decomposition (EMD) based R-peaks detection algorithms consume a considerable time of calculation caused by the large length of the input ECG signal, the design of a new technique that allows the acceleration of such methods becomes necessary. Accordingly, a new variant of an EMD-based strategy for R-peaks localization is presented. The new accelerated variant is constituted of three essential parts. The first step is the length reduction of the input signal by means of the truncation in the Fast Fourier Transform (FFT) domain followed by the application of the inverse FFT guaranteeing a suitable time-domain down-sampling. Consequently, the new input signal of a reduced length preserves all medical information contained initially in the original lengthy signal. The second part is dedicated to identify the QRS complex using EMD-based R-peaks detection. This latter comprises a low-pass filter, Empirical Mode Decomposition (EMD) and the Hilbert transform, Finally, the third phase is the time-domain up-sampling using the FFT, the zero padding and the Inverse Fast Fourier Transform (IFFT) to obtain a resulting processed signal which has the same length as the original signal. Next, as a post-processing step, final R-peaks refined localization is achieved. It is noticeable that the new variant ensures same results, in term of accuracy, as the standard method; however, a significant speed-up ratio of 6.95:1 is reported. Additionally, to more prove the effectiveness of the suggested strategy, it has been applied to accelerate two other efficient algorithms and satisfactory speed up ratios of, 7.20:1 and 4.23:1, respectively have been reached.","PeriodicalId":15161,"journal":{"name":"Journal of Biomimetics, Biomaterials and Biomedical Engineering","volume":"61 1","pages":"131 - 141"},"PeriodicalIF":0.7,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43451396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of Novel Prosthesis Implant Adapter by Finite Element Analysis 基于有限元分析的新型假体种植接头评价

IF 0.7

Journal of Biomimetics, Biomaterials and Biomedical Engineering Pub Date : 2023-07-31 DOI: 10.4028/p-N2yzeB

Marwa J. Jamal, S. Hamandi, M. N. Arbilei

引用次数: 1

Functionalization of Chitosan-TiO2 Nanotubes Scaffolds with Fibronectin for Bone Regeneration 壳聚糖-TiO2纳米管支架与纤连蛋白的功能化骨再生

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Journal of Biomimetics, Biomaterials and Biomedical Engineering Pub Date : 2023-07-31 DOI: 10.4028/p-k9wk3T

S. Lim, C. Chiang, N. Rosli, K. Chew

{"title":"Functionalization of Chitosan-TiO2 Nanotubes Scaffolds with Fibronectin for Bone Regeneration","authors":"S. Lim, C. Chiang, N. Rosli, K. Chew","doi":"10.4028/p-k9wk3T","DOIUrl":"https://doi.org/10.4028/p-k9wk3T","url":null,"abstract":"Composite scaffolds are promising regenerative medicines. Chitosan-TiO2 nanotubes (CTNTs) scaffold as a composite scaffold is, however, associated with low biocompatibility. This research aims to increase in vitro efficacy of CTNTs scaffolds by using fibronectin (FN) and investigate the adsorption affinity of such scaffolds towards FN. CTNTs scaffolds were prepared via direct blending of TiO2 nanotubes (TNTs) and chitosan solution. The mixture was then subjected to 24-h freezing and 24-h freeze drying. The scaffolds were further functionalized with FN solution (20, 40, 60, 80 and 100 μg/mL) via adsorption. The amount of adsorbed FN by the scaffolds was determined via colorimetric method. MG63 was used to evaluate the in vitro efficacy of CTNTs scaffolds with FN. The adsorption affinity of CTNTs scaffolds towards FN was high, as no saturation was achieved. The adsorption isotherm of FN onto CTNTs scaffolds fitted well with Temkin isotherm suggesting there was electrostatic interaction between the scaffolds and FN. Enhanced proliferation and early differentiation were observed in MG63 cultured on CTNTs scaffolds with FN. Particularly, CTNTs scaffolds functionalized with 60 μg/mL FN promoted the highest proliferation and early differentiation. CTNTs scaffolds with FN showed potential as scaffolding material for bone regeneration.","PeriodicalId":15161,"journal":{"name":"Journal of Biomimetics, Biomaterials and Biomedical Engineering","volume":"61 1","pages":"51 - 57"},"PeriodicalIF":0.7,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47491053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Design and Manufacturing a Portable Smart Sole for Measuring the Ground Reaction Force 测量地面反作用力的便携式智能鞋底的设计与制造

IF 0.7

Journal of Biomimetics, Biomaterials and Biomedical Engineering Pub Date : 2023-07-31 DOI: 10.4028/p-mrM7AX

F. M. Kadhim, S. Hasan, Rasha Qasim Humadi

{"title":"Design and Manufacturing a Portable Smart Sole for Measuring the Ground Reaction Force","authors":"F. M. Kadhim, S. Hasan, Rasha Qasim Humadi","doi":"10.4028/p-mrM7AX","DOIUrl":"https://doi.org/10.4028/p-mrM7AX","url":null,"abstract":"The systematic study of human locomotion known as gait analysis can be applied in various contexts, including athletics, rehabilitation, and clinical diagnoses. However, the present gait analysis methods have several limitations that make them inappropriate for individual use, such as the fact that they are expensive, non-portable, need a significant amount of time to set up, and require additional time for post-processing. This study aims to investigate and develop a gait analysis system to measure the vertical ground reaction forces. The measurement instrument qualities of being flexible, portable, and comfortable are essential to the design of wearable sensors. The device was calibrated using a universal testing machine (Force plate device). In addition, this study used flexible force sensors for detecting vGRF. The result shows the device works with high efficiency and accuracy in measurement when calculating the values of ground reaction force compared with the values of reaction force measured by the university testing machines. Keywords: Gait cycle, Ground reaction force, Arduino, Force plate, Smart sole","PeriodicalId":15161,"journal":{"name":"Journal of Biomimetics, Biomaterials and Biomedical Engineering","volume":"61 1","pages":"121 - 130"},"PeriodicalIF":0.7,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42131523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0