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The origin and evolution of lactation. 哺乳的起源和演变。
Journal of Biology Pub Date : 2009-01-01 Epub Date: 2009-04-24 DOI: 10.1186/jbiol139
Anthony V Capuco, R Michael Akers
{"title":"The origin and evolution of lactation.","authors":"Anthony V Capuco,&nbsp;R Michael Akers","doi":"10.1186/jbiol139","DOIUrl":"https://doi.org/10.1186/jbiol139","url":null,"abstract":"<p><p>The presence of mammary glands is the defining morphological feature of mammals. The recent assembly of the bovine genome and a report in Genome Biology that links the milk and lactation data of bovine and other mammalian genomes will help biologists investigate this economically and medically important feature.</p>","PeriodicalId":15075,"journal":{"name":"Journal of Biology","volume":"8 4","pages":"37"},"PeriodicalIF":0.0,"publicationDate":"2009-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/jbiol139","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28171174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 76
The human spermatozoon - a stripped down but refined machine. 人类的精子——一个被剥离但精细的机器。
Journal of Biology Pub Date : 2009-01-01 Epub Date: 2009-08-07 DOI: 10.1186/jbiol167
Christopher L R Barratt, Vanessa Kay, Senga K Oxenham
{"title":"The human spermatozoon - a stripped down but refined machine.","authors":"Christopher L R Barratt,&nbsp;Vanessa Kay,&nbsp;Senga K Oxenham","doi":"10.1186/jbiol167","DOIUrl":"https://doi.org/10.1186/jbiol167","url":null,"abstract":"<p><p>A recent paper in BMC Developmental Biology describes the development of the annulus of the mouse sperm cell, but much remains to be learnt about sperm cells despite their importance in human fertility.</p>","PeriodicalId":15075,"journal":{"name":"Journal of Biology","volume":"8 7","pages":"63"},"PeriodicalIF":0.0,"publicationDate":"2009-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/jbiol167","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28338011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 27
Beyond toxicity: aryl hydrocarbon receptor-mediated functions in the immune system. 超越毒性：免疫系统中芳基烃受体介导的功能。
Journal of Biology Pub Date : 2009-01-01 Epub Date: 2009-08-17 DOI: 10.1186/jbiol170
Brigitta Stockinger
{"title":"Beyond toxicity: aryl hydrocarbon receptor-mediated functions in the immune system.","authors":"Brigitta Stockinger","doi":"10.1186/jbiol170","DOIUrl":"10.1186/jbiol170","url":null,"abstract":"<p><p>The aryl hydrocarbon receptor is a ligand-activated transcriptional regulator that binds dioxin and other exogenous contaminants and is responsible for their toxic effects, including immunosuppression. New evidence suggests, however, that the aryl hydrocarbon receptor has a physiological role in the immune system, and the immunosuppressive effects of dioxin may reflect a more subtle disruption of the regulatory interactions between immune cells.</p>","PeriodicalId":15075,"journal":{"name":"Journal of Biology","volume":"8 7","pages":"61"},"PeriodicalIF":0.0,"publicationDate":"2009-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/jbiol170","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28350909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 31
Fishing for the signals that pattern the face. 寻找面部特征的信号。
Journal of Biology Pub Date : 2009-01-01 Epub Date: 2009-12-22 DOI: 10.1186/jbiol205
Thomas F Schilling, Pierre Le Pabic
{"title":"Fishing for the signals that pattern the face.","authors":"Thomas F Schilling,&nbsp;Pierre Le Pabic","doi":"10.1186/jbiol205","DOIUrl":"https://doi.org/10.1186/jbiol205","url":null,"abstract":"<p><p>Zebrafish are a powerful system for studying the early embryonic events that form the skull and face, as a model for human craniofacial birth defects such as cleft palate. Signaling pathways that pattern the pharyngeal arches (which contain skeletal precursors of the palate, as well as jaws and gills) are discussed in light of a recent paper in BMC Developmental Biology on requirements for Hedgehog signaling in craniofacial development.</p>","PeriodicalId":15075,"journal":{"name":"Journal of Biology","volume":"8 11","pages":"101"},"PeriodicalIF":0.0,"publicationDate":"2009-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/jbiol205","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28641207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 16
'Validation' in genome-scale research. 基因组规模研究中的“验证”。
Journal of Biology Pub Date : 2009-01-01 DOI: 10.1186/jbiol104
Timothy R Hughes
{"title":"'Validation' in genome-scale research.","authors":"Timothy R Hughes","doi":"10.1186/jbiol104","DOIUrl":"https://doi.org/10.1186/jbiol104","url":null,"abstract":"<p><p>The individual 'validation' experiments typically included in papers reporting genome-scale studies often do not reflect the overall merits of the work.</p>","PeriodicalId":15075,"journal":{"name":"Journal of Biology","volume":" ","pages":"3"},"PeriodicalIF":0.0,"publicationDate":"2009-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/jbiol104","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39969533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 23
The genomic 'inner fish' and a regulatory enigma in the vertebrates. 基因组的“内在鱼”和脊椎动物的调控之谜。
Journal of Biology Pub Date : 2009-01-01 Epub Date: 2009-04-16 DOI: 10.1186/jbiol131
John Malone, Brian Oliver
{"title":"The genomic 'inner fish' and a regulatory enigma in the vertebrates.","authors":"John Malone,&nbsp;Brian Oliver","doi":"10.1186/jbiol131","DOIUrl":"https://doi.org/10.1186/jbiol131","url":null,"abstract":"<p><p>Information on how genomic information from fish to human encodes the same tissues has until now emerged one gene at a time. The study published in this issue now provides lists of genes and their expression levels for 20 vertebrate tissues spanning 450 million years of vertebrate evolution. It reveals a core set of genes with similar tissue-expression patterns yet no common regulatory signatures--a gene-expression paradox.</p>","PeriodicalId":15075,"journal":{"name":"Journal of Biology","volume":"8 3","pages":"32"},"PeriodicalIF":0.0,"publicationDate":"2009-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/jbiol131","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28168493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Why do taste cells generate action potentials? 为什么味觉细胞会产生动作电位?
Journal of Biology Pub Date : 2009-01-01 Epub Date: 2009-04-28 DOI: 10.1186/jbiol138
Aurelie Vandenbeuch, Sue C Kinnamon
{"title":"Why do taste cells generate action potentials?","authors":"Aurelie Vandenbeuch,&nbsp;Sue C Kinnamon","doi":"10.1186/jbiol138","DOIUrl":"https://doi.org/10.1186/jbiol138","url":null,"abstract":"<p><p>Taste cells regularly generate action potentials, but their functional significance in taste signaling is unclear. A paper in BMC Neuroscience reveals the identity of the voltage-gated Na+ channels underlying action potentials, providing the foundation for insights into their function.</p>","PeriodicalId":15075,"journal":{"name":"Journal of Biology","volume":"8 4","pages":"42"},"PeriodicalIF":0.0,"publicationDate":"2009-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/jbiol138","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28172146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 41
Lateral inhibition and concentration-invariant odor perception. 侧抑制和浓度不变气味感知。
Journal of Biology Pub Date : 2009-01-01 Epub Date: 2009-01-26 DOI: 10.1186/jbiol106
Susy M Kim, Jing W Wang
{"title":"Lateral inhibition and concentration-invariant odor perception.","authors":"Susy M Kim,&nbsp;Jing W Wang","doi":"10.1186/jbiol106","DOIUrl":"https://doi.org/10.1186/jbiol106","url":null,"abstract":"<p><p>Sensory identity usually remains constant across a large intensity range. Vertebrates use lateral inhibition to match the sensitivity of retinal ganglion cells to the intensity of light. A new study published in Journal of Biology suggests that lateral inhibition in the Drosophila antennal lobe is similarly required for concentration-invariant perception of odors.</p>","PeriodicalId":15075,"journal":{"name":"Journal of Biology","volume":"8 1","pages":"4"},"PeriodicalIF":0.0,"publicationDate":"2009-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/jbiol106","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27985679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Biologists who count. 数数的生物学家。
Journal of Biology Pub Date : 2009-01-01 Epub Date: 2009-05-27 DOI: 10.1186/jbiol146
Miranda Robertson
{"title":"Biologists who count.","authors":"Miranda Robertson","doi":"10.1186/jbiol146","DOIUrl":"https://doi.org/10.1186/jbiol146","url":null,"abstract":"","PeriodicalId":15075,"journal":{"name":"Journal of Biology","volume":"8 4","pages":"34"},"PeriodicalIF":0.0,"publicationDate":"2009-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/jbiol146","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28212579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Letting go: modification of cell adhesion during apoptosis. 放手:细胞凋亡过程中细胞粘附的改变。
Journal of Biology Pub Date : 2009-01-01 Epub Date: 2009-05-28 DOI: 10.1186/jbiol152
Magali Suzanne, Hermann Steller
{"title":"Letting go: modification of cell adhesion during apoptosis.","authors":"Magali Suzanne,&nbsp;Hermann Steller","doi":"10.1186/jbiol152","DOIUrl":"https://doi.org/10.1186/jbiol152","url":null,"abstract":"<p><p>Apoptosis appears to be a carefully orchestrated process for the ordered dismantling of cells. A recent paper in BMC Developmental Biology shows that the disassembly of adherens junctions during apoptosis in Drosophila is progressive and requires the amino-terminal cleavage of the beta-catenin Armadillo by the apoptotic effector caspase DrICE.</p>","PeriodicalId":15075,"journal":{"name":"Journal of Biology","volume":"8 5","pages":"49"},"PeriodicalIF":0.0,"publicationDate":"2009-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/jbiol152","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28237204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 22
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