Journal of atrial fibrillation最新文献

{"title":"Left Atrial Appendage Occlusion Device Embolization (The LAAODE Study): Understanding the Timing and Clinical Consequences from a Worldwide Experience.","authors":"Ghulam Murtaza,&nbsp;Mohit K Turagam,&nbsp;Tawseef Dar,&nbsp;Krishna Akella,&nbsp;Bharath Yarlagadda,&nbsp;Steffen Gloekler,&nbsp;Bernhard Meier,&nbsp;Jacqueline Saw,&nbsp;Jung-Sun Kim,&nbsp;Hong-Euy Lim,&nbsp;Nietlispach Fabian,&nbsp;James Gabriels,&nbsp;Lucas V Boersmaj,&nbsp;Martin J Swaans,&nbsp;Mohmad Tantary,&nbsp;Sibghat Tul Llah,&nbsp;Apostolos Tzikas,&nbsp;Rakesh Gopinathannair,&nbsp;Dhanunjaya Lakkireddy","doi":"10.4022/jafib.2516","DOIUrl":"https://doi.org/10.4022/jafib.2516","url":null,"abstract":"<p><strong>Background: </strong>Left atrial appendage occlusion device embolization (LAAODE) is rare but can have substantial implications on patient morbidity and mortality. Hence, we sought to perform an analysis to understand the timing and clinical consequences of LAAODE.</p><p><strong>Methods: </strong>A comprehensive search of PubMed and Web of Science databases for LAAODE cases was performed from October 2nd, 2014 to November 1st, 2017. Prior to that, we included published LAAODE cases until October 1st, 2014 reported in the systematic review by Aminian et al.</p><p><strong>Results: </strong>103 LAAODE cases including Amplatzer cardiac plug (N=59), Watchman (N=31), Amulet (N=11), LAmbre (N=1) and Watchman FLX (N=1) were included. The estimated incidence of device embolization was 2% (103/5,000). LAAODE occurred more commonly in the postoperative period compared with intraoperative (61% vs. 39%). The most common location for embolization was the descending aorta 30% (31/103) and left atrium 24% (25/103) followed by left ventricle 20% (21/103). Majority of cases 75% (77/103) were retrieved percutaneously. Surgical retrieval occurred most commonly for devices embolized to the left ventricle, mitral apparatus and descending aorta. Major complications were significantly higher with postoperative LAAODE compared with intraoperative (44.4% vs. 22.5%, p=0.03).</p><p><strong>Conclusions: </strong>LAAODE is common with a reported incidence of 2% in our study. Post-operative device embolization occurred more frequently and was associated with a higher rate of complications than intraoperative device embolizations. Understanding the timings and clinical sequelae of DE can aid physicians with post procedural follow-up and also in the selection of patients for these procedures.</p>","PeriodicalId":15072,"journal":{"name":"Journal of atrial fibrillation","volume":" ","pages":"2516"},"PeriodicalIF":0.0,"publicationDate":"2021-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8691350/pdf/jafib-13-02516.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39621007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Meta-Analysis of Catheter Ablation Compared with Drug Therapy as First Line Treatment Strategy of Paroxysmal Atrial-Fibrillation.","authors":"Ashish Kumar,&nbsp;Ahmad Al-Abdouh,&nbsp;Harshvardhan Zala,&nbsp;Ahmad Jabri,&nbsp;Awani Deshmukh,&nbsp;Abhishek Deshmukh","doi":"10.4022/jafib.2464","DOIUrl":"https://doi.org/10.4022/jafib.2464","url":null,"abstract":"","PeriodicalId":15072,"journal":{"name":"Journal of atrial fibrillation","volume":" ","pages":"2464"},"PeriodicalIF":0.0,"publicationDate":"2021-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8691348/pdf/jafib-13-02464.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39621001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Same-Day Versus Next-Day Discharge Strategies for Left Atrial Ablation Procedures: A Parallel, Intra-Institutional Comparison of Safety and Feasibility.","authors":"Matthew T Brown,&nbsp;Mary M Pelling,&nbsp;Soroosh Kiani,&nbsp;Faisal M Merchant,&nbsp;Mikhael F El-Chami,&nbsp;Angel R Leon,&nbsp;Stacy Westerman,&nbsp;Anand Shah,&nbsp;Donna Wise,&nbsp;Michael S Lloyd","doi":"10.4022/jafib.2466","DOIUrl":"https://doi.org/10.4022/jafib.2466","url":null,"abstract":"<p><strong>Background: </strong>Head-to-head comparative data for the postoperative care of patients undergoing left atrial ablation procedures are lacking.</p><p><strong>Objective: </strong>We sought to investigate complication and readmission rates between patients undergoing same-day (SD) or next-day (ND) discharges for ablative procedures in the left atrium, primarily atrial fibrillation (AF).</p><p><strong>Methods: </strong>Two electrophysiology centers simultaneously perform left atrial ablations with differing discharge strategies. We identified all patients who underwent left atrial ablation from August 2017 to August 2019 (n = 409) undergoing either SD (n = 210) or ND (n = 199) discharge protocols. We analyzed any clinical events that resulted in procedural abortion, extended hospitalization, or readmission within 72 hours.</p><p><strong>Results: </strong>The primary endpoint of complication and readmission rate was similar between SD and ND discharge (14.3% vs 12.6%, p = 0.665). Rates of complications categorized as major (2.4% vs 3.0%, p = 0. 776) and minor (11.9% vs 9.5%, p = 0.524) were also similar.Multivariable regression modeling revealed no significant correlation between discharge strategy and complication/readmission occurrence (OR 1.565 [0.754 - 3.248], p = 0.23), but a positive association of hypertension and procedure duration (OR 3.428 [1.436 - 8.184], p = 0.006) and (OR 1.01 [1 - 1.019], p = 0.046) respectively.</p><p><strong>Conclusions: </strong>Left atrial ablation complication and readmission rates were similar between SD and ND discharge practices. Hypertension and procedural duration were associated with increased complication rates irrespective of discharge strategy. These data, which represent the first side-by-side comparison of discharge strategy, suggests same-day discharge is safe and feasible for left atrial ablation procedures.</p>","PeriodicalId":15072,"journal":{"name":"Journal of atrial fibrillation","volume":" ","pages":"2466"},"PeriodicalIF":0.0,"publicationDate":"2021-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8691351/pdf/jafib-13-02466.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39621002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intraluminal Esophageal Temperature Monitoring Using the Circa S-Cath™ Temperature Probe to Guide Left Atrial Ablation in Patients with Atrial Fibrillation.","authors":"Lisa Wm Leung,&nbsp;Zaki Akhtar,&nbsp;Jamal Hayat,&nbsp;Mark M Gallagher","doi":"10.4022/jafib.2508","DOIUrl":"10.4022/jafib.2508","url":null,"abstract":"Corresponding Author Lisa WM Leung, St George’s Hospital, Blackshaw Road, London SW17 0QT","PeriodicalId":15072,"journal":{"name":"Journal of atrial fibrillation","volume":" ","pages":"2508"},"PeriodicalIF":0.0,"publicationDate":"2021-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8691354/pdf/jafib-13-02508.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39621006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"SANS FLUORO Too Big to Fail.","authors":"Robert L Percell,&nbsp;Matthew E Johnson,&nbsp;Raghuveer Dendi","doi":"10.4022/jafib.2453","DOIUrl":"https://doi.org/10.4022/jafib.2453","url":null,"abstract":"<p><p>We present the first ever reported case of a super morbidly obese patient (BMI > 60) with drug refractory, symptomatic persistent atrial fibrillation who underwent an uncomplicated, but unsuccessful PVI ablation procedure and subsequently underwent AV node ablation and cardiac resynchronization therapy - pacemaker (CRT-P) insertion using a zero fluoroscopy technique. This case demonstrates the following two critical points: (1) difficulties in the treatment of massively obese patients with arrhythmias1; (2) increased use of fluoroless procedures2-4.</p>","PeriodicalId":15072,"journal":{"name":"Journal of atrial fibrillation","volume":" ","pages":"2453"},"PeriodicalIF":0.0,"publicationDate":"2021-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8691357/pdf/jafib-13-02453.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39760641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ICE-Derived Left Atrial and Left Ventricular Endocardial and Myocardial Speckle Tracking Strain Patterns in Atrial Fibrillation at the Time of Radiofrequency Ablation.","authors":"Jian-Fang Ren,&nbsp;Shiquan Chen,&nbsp;David J Callans,&nbsp;Qiang Liu,&nbsp;Gregory Supple,&nbsp;David S Frankel,&nbsp;Pasquale Santangeli,&nbsp;Ruhong Jiang,&nbsp;David Lin,&nbsp;Matthew Hyman,&nbsp;Lu Yu,&nbsp;Michael Riley,&nbsp;Yaxun Sun,&nbsp;Zuwen Zhang,&nbsp;Chan Yu,&nbsp;Robert D Schaller,&nbsp;Sanjay Dixit,&nbsp;Bei Wang,&nbsp;Chenyang Jiang,&nbsp;Francis E Marchlinski","doi":"10.4022/jafib.2509","DOIUrl":"https://doi.org/10.4022/jafib.2509","url":null,"abstract":"<p><strong>Objectives: </strong>Intracardiac echocardiography(ICE) has excellent imaging resolution and border recognition which increase strain measurement accuracy. We hypothesized that left atrial(LA) substrate and functional impairment can be detected by measuring LA strain deformation in patients with persistent and paroxysmal atrial fibrillation(AF), as compared to those with no AF. Strain deformation changes in LA and left ventricle(LV) can also be assessed post-ablation to determine its effect.</p><p><strong>Methods: </strong>ICE-derived speckle tracking strain(STS) was prospectively performed in 96 patients, including 62 patients with AF(31 persistent and 31 paroxysmal AF) pre-/post-ablation, and 34 patients with no AF. We measured major strain parameters including longitudinal segmental(endo/myocardial) \"average peak overall strain of all segments\"(PkAll), peak strain rate(SR),and different time-to-peak strain in LA and LV images.</p><p><strong>Results: </strong>At baseline, persistent AF patients had significantly lower(p<0.01) LA endocardial(4.3±2.5 vs. 20.3±8.9 and 25.5±12.9 %) and myocardial PkAll(4.4±2.6 vs. 15.7±7.2 and 20.9±9.2 %), endocardial(0.9±0.4 vs. 1.8±0.7 and 2.2±0.6 1/s) and myocardial peak SR(0.7±0.4 vs. 1.5±0.6 and 1.9±0.5 1/s), as compared to paroxysmal AF and no AF patients. After successful ablation, endo-/myocardial LA PkAll and peak SR were significantly improved, most dramatically in patients with persistent AF. LV endocardial/myocardial strain and SR also improved in AF patients post-ablation.</p><p><strong>Conclusion: </strong>LA longitudinal strain(%)/SR(1/s) parameters in AF patients are more abnormal than those with no AF, suggesting LA substrate/functional damage. AF ablation improved LA strains/SR but with values in paroxysmal > persistent AF suggesting background LA damage in persistent AF.</p>","PeriodicalId":15072,"journal":{"name":"Journal of atrial fibrillation","volume":"13 5","pages":"2509"},"PeriodicalIF":0.0,"publicationDate":"2021-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8691347/pdf/jafib-13-02509.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10085325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Intensive Blood Pressure Lowering on Incident Atrial Fibrillation: A Systematic Review and Meta-Analysis.","authors":"Matthew J Singleton,&nbsp;Lin Y Chen,&nbsp;S Patrick Whalen,&nbsp;Prashant D Bhave,&nbsp;Elijah H Beaty,&nbsp;Joseph Yeboah,&nbsp;Elsayed Z Soliman","doi":"10.4022/jafib.2401","DOIUrl":"https://doi.org/10.4022/jafib.2401","url":null,"abstract":"<p><p>The effect of intensive versus standard blood pressure (BP) lowering on the risk of atrial fibrillation (AF) is uncertain. Intensive BP lowering is associated with a lower risk of AF among patients with hypertension. We searched PubMed, EMBASE, and CENTRAL (inception to June 5, 2020) for randomized controlled trials evaluating the effect of intensive versus standard (target systolic BP < 140 mmHg) BP lowering on incident AF. We assessed heterogeneity using the I2 statistic then used fixed-effects meta-analysis models to report pooled treatment effects and 95% confidence intervals. We also tested for publication bias by three funnel plot-based methods. The quality of each study was assessed with the Cochrane Risk of Bias tool. We assessed 16 candidate studies for eligibility from 2,312 published articles, but only three randomized clinical trials were eligible for inclusion and included a combined 12,219 participants with hypertension: Cardio-Sis (Studio Italiano Sugli Effetti Cardiovascolari del Controllo della Pressione Arteriosa Sistolica), ACCORD-BP (Action to Control Cardiovascular Risk in Diabetes Blood Pressure trial), and SPRINT (Systolic Blood Pressure Intervention Trial). The target systolic BP in the intensive BP arm was <120 mmHg for participants in SPRINT and ACCORD-BP, but <130 mmHg for participants in Cardio-Sis. Participants randomized to intensive BP lowering had significantly lower risk of incident AF compared with those randomized to standard BP lowering (AF incidence 2.2% vs. 3.0%, respectively; pooled hazard ratio (95% confidence interval): 0.74 (0.59 - 0.93)). Intensive BP lowering is associated with a significantly lower risk of incident AF in patients with hypertension. These findings add to the current evidence supporting the benefits of intensive BP control.</p>","PeriodicalId":15072,"journal":{"name":"Journal of atrial fibrillation","volume":"13 4","pages":"2401"},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8691291/pdf/jafib-13-02401.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39758641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recurrent Takotsubo Cardiomyopathy During Cryoablation Procedure for Atrial Fibrillation: A Case Report.","authors":"Nadeem Khan,&nbsp;Alejandro Jimenez Restrepo,&nbsp;Sanjay Kumar","doi":"10.4022/jafib.2446","DOIUrl":"https://doi.org/10.4022/jafib.2446","url":null,"abstract":"<p><p>We report a case of 72-year-old female with prior history of takotsubo cardiomyopathy (TSC) who had recurrence of TSC during cryoablation of pulmonary veins for atrial fibrillation (AF) ablation. This case is unique because this is the first report of TSC detected during cryoablation and the procedure being stressor for recurrent TSC. We discuss possible mechanism of TSC and management of this case. Readers would have higher alertness of detecting TSC during AF ablation and therefore would be able to manage this serious condition properly.</p>","PeriodicalId":15072,"journal":{"name":"Journal of atrial fibrillation","volume":"13 4","pages":"2446"},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8691292/pdf/jafib-13-02446.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39760637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intraluminal Esophageal Temperature Monitoring Using the Circa S-Cath™ Temperature Probe to Guide Left Atrial Ablation in Patients with Atrial Fibrillation.","authors":"Sapan Bhuta,&nbsp;Jonathan Hsu,&nbsp;Kurt S Hoffmayer,&nbsp;Michael Mello,&nbsp;Thomas Savides,&nbsp;Malek Bashti,&nbsp;Jessica Hunter,&nbsp;Kathryn Lewis,&nbsp;Gregory K Feld","doi":"10.4022/jafib.2386","DOIUrl":"https://doi.org/10.4022/jafib.2386","url":null,"abstract":"Introduction Radiofrequency catheter ablation is a common treatment for atrial fibrillation (AF), during which thermal esophageal injury may rarely occur and lead to an atrio-esophageal fistula. Therefore, we studied the utility of the Circa S-Cath™ multi-sensor luminal esophageal temperature (LET) probe to prevent esophageal thermal injury. Methods and Results Thirty-six patients, enrolled prospectively, underwent circumferential or segmental pulmonary vein isolation for treatment of AF. A maximum ablation electrode temperature of 42ºC was programmed for automatic power delivery cutoff. In addition, energy delivery was manually discontinued when the maximum LET on any sensor of the probe rose abruptly (i.e. ˃0.2ºC) or exceeded 39º C. Esophagoscopy was performed immediately after ablation in 18 patients (with the temperature probe still in place) and at approximately 24 hours after ablation in 18 patients. Esophageal lesions were classified as likely traumatic or thermally related. Of the 36 patients enrolled in the study, 21 had persistent and 15 had paroxysmal AF, average LVEF 57±16% and CHA2DS2VASc score 1.6±1.2 (range 0-4). Average maximum LET was 37.8±1.4ºC, power delivery 31.1±8 watts and ablation electrode temperature 36.4±4.1ºC. Average maximum contact force was 44.5±20.5 grams where measured. Only 1 patient (<3%) had an esophageal lesion that could potentially represent thermal injury and 4 patients (11.1%) had minor traumatic mechanical injury. Conclusions LET guided titration of power and duration of energy application, using an insulated multi-sensor esophageal temperature probe, is associated with a low risk of esophageal thermal injury during AF ablation. In only rare cases, LET monitoring resulted in the need to manipulate the esophagus to avoid unacceptable temperature rises, that could not be achieved by adjustment of power and duration of energy application.","PeriodicalId":15072,"journal":{"name":"Journal of atrial fibrillation","volume":"13 4","pages":"2386"},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8691294/pdf/jafib-13-02386.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39758639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Role of Magnesium in the Management of Atrial Fibrillation with Rapid Ventricular Rate.","authors":"Harneet Bhatti,&nbsp;Billal Mohmand,&nbsp;Niranjan Ojha,&nbsp;Christos P Carvounis,&nbsp;Robert L Carhart","doi":"10.4022/jafib.2389","DOIUrl":"https://doi.org/10.4022/jafib.2389","url":null,"abstract":"<p><strong>Background: </strong>Atrial fibrillation is currently managed with a variety of rate controlling and antiarrhythmic agents. Often, magnesium is used as adjunctive therapy, however, the benefit it provides in managing Afib with RVR has been debated. This study aimed to determine if IV MgSO4 administration in conjunction with standard therapy provides any synergistic effect in acute and prolonged control of Afib with RVR.</p><p><strong>Methods: </strong>This was a retrospective study involving ninety patients with episodes of Afib with RVR during their hospitalization. The treatment group included those that had received magnesium (n=32) along with standard management and the control group (n=58) received only standard management. Heart rates at different time intervals were collected. Dose dependent effects of IV MgSO4 on heart rates were also evaluated.</p><p><strong>Results: </strong>Patients that received magnesium had a lower mean heart rate (85 BPM versus 96 BPM, P<0.05) 24 hours after onset of the episode. Also, in the last 16 hours of observation, it appeared that administration of higher levels of magnesium resulted in statistically lower heart rates. In the group of patients that received 2 grams of magnesium, the mean heart rate at 8 hours was 103.4 beats/min and 84.8 beats/min at 24 hours (p<0.01). This same trend was not seen in patients that received 1 gram of magnesium or in the control group.</p><p><strong>Conclusions: </strong>Overall, the use of IV MgSO4 as an adjunctive treatment permitted normalization of the heart rate progressively that continued to at least 24 hours.</p>","PeriodicalId":15072,"journal":{"name":"Journal of atrial fibrillation","volume":"13 4","pages":"2389"},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8691303/pdf/jafib-13-02389.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39758640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}