{"title":"Evaluation of the Antibacterial Potential of the Phytochemicals in Leaf Extracts of Newboudia laevis on Uropathogens","authors":"F. Alao, Z. S. Ololade, Yusuf A. Fagge","doi":"10.35248/2155-9597.21.S10.003","DOIUrl":"https://doi.org/10.35248/2155-9597.21.S10.003","url":null,"abstract":"This study was conducted to determine the secondary metabolites and antibacterial potential of the leaf extracts Newbouldia laevis on some uropathogen strains and also to carry out phytochemical screening of the sample. The antibacterial activity of N. laevis leaves extracted with methanol, hot and cold water were evaluated against medically important bacteria strains of Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Staphylococcus saprophyticus and Enterococcus faecalis. The results showed a remarkable inhibition of the bacteria growth against the tested organisms with Staphylococcus saprophyticus had highest activity (20 mm). In general, all the tested organisms showed a significant activity with the extracts. The conventional antibiotics used against these organisms showed that all the isolates were resistant to augmentin, ceftazidime, cefuroxime, and cloxacillin. The phytochemical analysis of the plants was carried out. The microbial activity of the Newbouldia laevis was due to the presence of various secondary metabolites. The GC-MS analysis showed that the most abundant phytochemical in the extract is linoleoyl chloride (76.3%). Hence, these plants can be used to discover bioactive natural products that may serve as leads in the development of new pharmaceuticals research activities.","PeriodicalId":15045,"journal":{"name":"Journal of Bacteriology & Parasitology","volume":"12 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77162661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Tsegaye, Yizengaw Aniley, Belete Negese, Zemen Mengesha
{"title":"Assessment of Knowledge and Practice of House Hold Water Treatment and Associated Factors in Rural Kebeles of Degadamot Woreda, North-West Ethiopia, 2020","authors":"D. Tsegaye, Yizengaw Aniley, Belete Negese, Zemen Mengesha","doi":"10.35248/2155-9597.21.12.403","DOIUrl":"https://doi.org/10.35248/2155-9597.21.12.403","url":null,"abstract":"Background: Household water treatment and safe storage interventions are proven to improve water quality and reduce diarrheal disease incidence in developing countries. Almost 90% of the rural population of Ethiopia did not practice any alternative water treatment methods which would pose them to high public health risks. The aim of this study was therefore to identify factors of house hold water treatment practice and knowledge in rural kebeles of Degadamot woreda, North West Ethiopia, 2020. Methods: A Community-based cross-sectional study design was conducted in Degadamot woreda, North West Ethiopia, 2020. A Multistage sampling technique was carried out to select 845 sample households. Data were entered into the Epi-Data version 4.1 and analyzed using SPSS Version 20. Binary Logistic regression analysis was conducted to identify factors of house hold water treatment practice and knowledge. Results: In this study, 14% of participants were practicing household water treatment and 28.2% had knowledge on household water treatment practice. Educational status, income earning >600 ETB per month, number of under five children in the household, ways to fetch water and knowledge on HWT were factors significantly associated with household water treatment practice. And educational status, marital status, source of water for drinking, number of containers to store water two, three and above: and place of handling utensils were factors which had significant association with knowledge of house hold water treatment practice. Conclusion: Factors that were significantly associated with household water treatment practice were educational status, income, number of under-five children, ways to fetch drinking water and good knowledge about household water treatment.","PeriodicalId":15045,"journal":{"name":"Journal of Bacteriology & Parasitology","volume":"24 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87834444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bacterial Blood Stream Infection in Southern Ethiopia","authors":"M. Hailemariam, Tsegaye Alemayehu, asnakech agegnehu, Mulubrhan Ali, Enkosilassie Mitiku, Elshaday Azerefegne","doi":"10.35248/2155-9597.21.S8.003","DOIUrl":"https://doi.org/10.35248/2155-9597.21.S8.003","url":null,"abstract":"Background: Children’s blood stream infections mainly due to resistant pathogens found to be a higher risk of hospital mortality in low and middle income countries. This study intended to assess the bacterial profile and drug resistance of isolates of blood stream infection among under- 5 children in Southern Ethiopia. Methods: Retrospectively lab recorded data’s were retrieved to assess the bacterial isolates and rates antibiotic resistance at Hawassa University Comprehensive Specialized Hospital. Results: Of 323 bloods culture performed 116 (35.9%) were positive for potential bacterial BSI. Positivity of blood culture decrease with age, hence neonates blood stream infection stream infection were higher than other age groups (OR, 3; 95% CI 1.5–5.1; p=0.001). The major gram positive isolate CoNS and S. aureus have shown highest level of resistance to penicillin 61.3% and tetracycline 78.8% whereas less level of resistance was reported to Meropenem 6.4%, Ceftriaxone 13% and doxycycline 13%. Although most of gram negatives isolates were resistant for tested antibiotics, K. pneumoniae has shown leaser resistance to cefotaxime and chloramphenicol. Conclusion: A high level of blood stream infection accompanied by high drug resistant isolates was reported. The great burden in neonate than other children was reported. As a result to reduce the burden the hospital administrators need to facilities effective infection prevention and control programmes, effective hygiene practices and well-functioning environment along with educating patient about proper hygiene practices.","PeriodicalId":15045,"journal":{"name":"Journal of Bacteriology & Parasitology","volume":"242 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80518028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Oxysterols: A New Hope for an Effective and Safe Therapy for COVID-19, Another Light at the End of the Tunnel","authors":"F. Parhami, Feng Wang, F. Stappenbeck","doi":"10.35248/2155-9597.21.12.404","DOIUrl":"https://doi.org/10.35248/2155-9597.21.12.404","url":null,"abstract":"The COVID-19 pandemic and its lasting consequences have dealt a huge, irreversible blow to the vitality of the global economy and the livelihood of all populations affected by it. Millions of lives lost, businesses destroyed, hopes and dreams shattered and the pandemic still persists despite the remarkable impact of newly developed vaccines. Unfortunately, there are still many uncertainties that threaten our future: • Harmful new variants of SARS-CoV-2, the COVID-19 virus, emerging from a constantly mutating virus that may render the existing vaccines less effective or even ineffective. • The colossal task of vaccinating the entire world population, combined with a likely need for repeat vaccination. • The side effects of the available vaccines, especially in certain segments of the population, including young men and pregnant or to be pregnant women. Unfortunately, not much is currently known about potential long term side effects of the newly developed vaccines.","PeriodicalId":15045,"journal":{"name":"Journal of Bacteriology & Parasitology","volume":"39 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88679124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Rodríguez, Mondeja Ba, Lau Ld, A. Vizcaino, Acosta Ef, Y. González
{"title":"The SARS-Cov-2 Novel Coronavirus: A Reflection about Enhancement of High-Resolution Microscopic Images","authors":"R. Rodríguez, Mondeja Ba, Lau Ld, A. Vizcaino, Acosta Ef, Y. González","doi":"10.35248/2155-9597.21.S10.004","DOIUrl":"https://doi.org/10.35248/2155-9597.21.S10.004","url":null,"abstract":"After a year of hard battling with the novel coronavirus SARS Cov-2, the COVID-19 pandemic continues had a catastrophic effect on society and health worldwide. This pandemic has changed labor and economic relations in almost every country in the world, and the investment that has been made in the development of new treatment protocols and the creation of vaccines has been enormous. Important laboratories, hospitals and research centers around the world have been fighting against SARS-Cov-2, and within these researches computer vision has played a prominent role. The main aim of this work is to carry out a reflection on the enhancement of the microscopic images of the novel coronavirus SARS-Cov-2 from the results obtained and published. We will analyze the effectiveness of the algorithms proposed to highlight the S-spikes, and we will detail why deep learning, despite the popularity achieved, in this case was not beneficial.","PeriodicalId":15045,"journal":{"name":"Journal of Bacteriology & Parasitology","volume":"17 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83107101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Strongyloides Stercoralis Infection in a Case of Ankylosing Spondylitis","authors":"L. Pezone","doi":"10.35248/2155-9597.21.12.393","DOIUrl":"https://doi.org/10.35248/2155-9597.21.12.393","url":null,"abstract":"A 69 year old man was admitted in the hospital with chief complaints of fever of 2 days duration, swelling and pain of lower limb and knee joint for 4 days. He was a known case of ankylosing spondylitis for last 10 years with chronic intake of corticosteroids. On admission the patient was diagnosed with right lower limb cellulitis and right lung consolidation and pleural effusion. Blood culture and synovial fluid culture showed growth of Staphylococcus aureus. 2 days later patient complained of diarrhoea. Routine stool examination showed plenty of rhabditiform Strongyloides Stercoralis larva. The patient was treated with Ivermectin for Strongyloides and was discharged after total resolution of infection with advice of regular follow-ups for any dissemination or hyperinfection.","PeriodicalId":15045,"journal":{"name":"Journal of Bacteriology & Parasitology","volume":"27 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79259130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Sargın, Mert Akbulut, S. Karaduman, H. Sungurtekin
{"title":"Severe Rhinocerebral Mucormycosis Case Developed after COVID-19","authors":"F. Sargın, Mert Akbulut, S. Karaduman, H. Sungurtekin","doi":"10.36648/2155-9597.21.12.386","DOIUrl":"https://doi.org/10.36648/2155-9597.21.12.386","url":null,"abstract":"In this article, a case of rhinocerebral mucormycosis developing after COVID-19 infection in a diabetic patient is presented. Early diagnosis and treatment of those high morbidity conditions is vital to better outcomes.","PeriodicalId":15045,"journal":{"name":"Journal of Bacteriology & Parasitology","volume":"46 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72857025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Diop-Ndiaye, A. Dieng, A. Gaye, A. Ba-Diallo, Lobach Sm, A. Tinè, M. Mboup, Ndiaye Ajs, Diaz Cf, B. Dembele, Ngom Cs, N. Sene, A. Diouf, A. Sow, A. Sarr, B. Ndiaye, H. Diagne, M. Camara, Boye Csb
{"title":"Sexually Transmitted Pathogens in Key Populations Attending the Institute of Social Hygiene Hospital in Dakar, Senegal","authors":"H. Diop-Ndiaye, A. Dieng, A. Gaye, A. Ba-Diallo, Lobach Sm, A. Tinè, M. Mboup, Ndiaye Ajs, Diaz Cf, B. Dembele, Ngom Cs, N. Sene, A. Diouf, A. Sow, A. Sarr, B. Ndiaye, H. Diagne, M. Camara, Boye Csb","doi":"10.35248/2155-9597.21.12.395","DOIUrl":"https://doi.org/10.35248/2155-9597.21.12.395","url":null,"abstract":"Introduction: Chlamydia trachomatis urogenital infection is one of the leading causes of bacterial Sexually Transmitted Infections (STIs) and responsible for many complications. This study aimed to assess the prevalence of sexually transmitted pathogens in key populations in Senegal. Materials and methods: A retrospective study from January to December 2018 was carried out at the Institute of Social Hygiene in 2 key populations namely Men who have Sex with Men (MSM) and Female Sex Workers (FSW) presented symptoms of STIs. For each patient, blood samples and urethral or vaginal sample were collected. Diagnostic of STIs microorganisms including Treponema pallidum, C. trachomatis, Neisseria gonorrhoeae and Trichomonas vaginalis was performed. Results: Two hundred fourteen patients (173 FSW and 41 MSMS) with STIs symptoms were included in this study. STI diagnosis was confirmed in 176 participants giving an overall STIs rate of 82% (176/214). Among them, 80% (141/176) were FSW and 20% (35/176) were MSM. C. trachomatis was found in 55% of cases (97/176) followed by N. gonorrhoeae (18%; n=32/176), T. vaginalis (15%; n=26/176) and T. Pallidum (12%; n=21/176). Interestingly, C. trachomatis infection was exclusively detected in FSW with a rate of 68.8% (97/141). In addition, C. trachomatis was associated with other STIs agents in 22 cases (23%) namely T. pallidum (5.2%; n=5/97), N. gonorrhoeae (3.1%; n=3/97), and T. vaginalis (14.4%; n=14/97). C. trachomatis was found in all age groups, however, young people (<30 years) seems to be more affected with 58.8% (57/97). Conclusion: This study showed a predominance of C. trachomatis infections among FSW suggesting the importance to consider this STI’s pathogen in the management of key populations in Senegal.","PeriodicalId":15045,"journal":{"name":"Journal of Bacteriology & Parasitology","volume":"70 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76177948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Commentary on the Corona Virus before the Next Pandemic","authors":"J. Slingenbergh","doi":"10.35248/2155-9597.21.12.390","DOIUrl":"https://doi.org/10.35248/2155-9597.21.12.390","url":null,"abstract":"Making it to the next host goes to the heart of virus fitness. There are in this regard two broadly opposing virus life history strategies. Acute viruses tend to be replicative and swiftly transmit to the next host. Instead, a persistent virus may be shed in minor quantities, if at all, keeping virus replication costs and host damage to a minimum.","PeriodicalId":15045,"journal":{"name":"Journal of Bacteriology & Parasitology","volume":"107 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76324090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Telemedicine in Time of COVID-19","authors":"John R Maese, D. Seminara, Zeel Shah","doi":"10.36648/2155-9597.21.12.389","DOIUrl":"https://doi.org/10.36648/2155-9597.21.12.389","url":null,"abstract":"It is safe to say that 2020 has been an extraordinary year. In the past nine months, we have seen changes in telehealth that we could not accomplish in the past 15 years. The alignment of technology, policy and reimbursement have been powerful forces that have propelled telemedicine into the 21st century.","PeriodicalId":15045,"journal":{"name":"Journal of Bacteriology & Parasitology","volume":"46 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74412868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}