{"title":"Bacterial Blood Stream Infection in Southern Ethiopia","authors":"M. Hailemariam, Tsegaye Alemayehu, asnakech agegnehu, Mulubrhan Ali, Enkosilassie Mitiku, Elshaday Azerefegne","doi":"10.35248/2155-9597.21.S8.003","DOIUrl":null,"url":null,"abstract":"Background: Children’s blood stream infections mainly due to resistant pathogens found to be a higher risk of hospital mortality in low and middle income countries. This study intended to assess the bacterial profile and drug resistance of isolates of blood stream infection among under- 5 children in Southern Ethiopia. Methods: Retrospectively lab recorded data’s were retrieved to assess the bacterial isolates and rates antibiotic resistance at Hawassa University Comprehensive Specialized Hospital. Results: Of 323 bloods culture performed 116 (35.9%) were positive for potential bacterial BSI. Positivity of blood culture decrease with age, hence neonates blood stream infection stream infection were higher than other age groups (OR, 3; 95% CI 1.5–5.1; p=0.001). The major gram positive isolate CoNS and S. aureus have shown highest level of resistance to penicillin 61.3% and tetracycline 78.8% whereas less level of resistance was reported to Meropenem 6.4%, Ceftriaxone 13% and doxycycline 13%. Although most of gram negatives isolates were resistant for tested antibiotics, K. pneumoniae has shown leaser resistance to cefotaxime and chloramphenicol. Conclusion: A high level of blood stream infection accompanied by high drug resistant isolates was reported. The great burden in neonate than other children was reported. As a result to reduce the burden the hospital administrators need to facilities effective infection prevention and control programmes, effective hygiene practices and well-functioning environment along with educating patient about proper hygiene practices.","PeriodicalId":15045,"journal":{"name":"Journal of Bacteriology & Parasitology","volume":"242 1","pages":"1-6"},"PeriodicalIF":0.0000,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Bacteriology & Parasitology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.35248/2155-9597.21.S8.003","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Children’s blood stream infections mainly due to resistant pathogens found to be a higher risk of hospital mortality in low and middle income countries. This study intended to assess the bacterial profile and drug resistance of isolates of blood stream infection among under- 5 children in Southern Ethiopia. Methods: Retrospectively lab recorded data’s were retrieved to assess the bacterial isolates and rates antibiotic resistance at Hawassa University Comprehensive Specialized Hospital. Results: Of 323 bloods culture performed 116 (35.9%) were positive for potential bacterial BSI. Positivity of blood culture decrease with age, hence neonates blood stream infection stream infection were higher than other age groups (OR, 3; 95% CI 1.5–5.1; p=0.001). The major gram positive isolate CoNS and S. aureus have shown highest level of resistance to penicillin 61.3% and tetracycline 78.8% whereas less level of resistance was reported to Meropenem 6.4%, Ceftriaxone 13% and doxycycline 13%. Although most of gram negatives isolates were resistant for tested antibiotics, K. pneumoniae has shown leaser resistance to cefotaxime and chloramphenicol. Conclusion: A high level of blood stream infection accompanied by high drug resistant isolates was reported. The great burden in neonate than other children was reported. As a result to reduce the burden the hospital administrators need to facilities effective infection prevention and control programmes, effective hygiene practices and well-functioning environment along with educating patient about proper hygiene practices.