Journal of Bacteriology & Parasitology最新文献_第10页

Investigation of In Vivo Effects of Trichomonas Vaginalis on Visceral Organs 阴道毛滴虫体内对脏器影响的研究

Journal of Bacteriology & Parasitology Pub Date : 2017-11-13 DOI: 10.4172/2155-9597.1000327

Akyshbayeva Kulbarshin, S. Elmira, Ramazanova Bakyt, Kushugulova Almagul, Khassenbekova Zhanagul, S. Sergazy, M. Alía

{"title":"Investigation of In Vivo Effects of Trichomonas Vaginalis on Visceral Organs","authors":"Akyshbayeva Kulbarshin, S. Elmira, Ramazanova Bakyt, Kushugulova Almagul, Khassenbekova Zhanagul, S. Sergazy, M. Alía","doi":"10.4172/2155-9597.1000327","DOIUrl":"https://doi.org/10.4172/2155-9597.1000327","url":null,"abstract":"Background: Urogenital trichomoniasis (UGT) is the most common sexually transmitted disease in Kazakhstan. Association of T. vaginalis infection with the development of ascites and multiple visceral abscesses was shown in experiments with intraperitoneal injection of infectious material. The effect of T. vaginalis on visceral organs in natural infection is unknown. \u0000Materials and methods: T.vaginalis effect on visceral organs was assessed with the model previously developed by us (\"The Method of Urogenital Trichomoniasis Simulation\", patent application No. 06 331 dated April 1, 2016). It was ethically carried out on animals with the approval of the KazNMU Ethics Committee (Registration No. 191). The material for histological and cytological studies was prepared in accordance with the conventional methods. \u0000Result: The changes was found in all visceral organs, most pronounced in hepatic parenchyma: parenchymal degeneration and necrosis of hepatocytes, significant edema with cellular infiltration in the portal tracts and separation of blood plasma from the formed elements in blood vessels representing changes in rheological properties of blood. Expressed changes were also observed in renal tissues. Less pronounced changes were observed in lung tissues. \u0000Conclusions: The results of our study showed high activity of T. vaginalis in visceral organs.","PeriodicalId":15045,"journal":{"name":"Journal of Bacteriology & Parasitology","volume":"56 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2017-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73839370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Genotypic Characteristics of Outpatient Antibiotic Resistance and Nosocomial Staphylococcus aureus Strains 门诊金黄色葡萄球菌耐药及院内金黄色葡萄球菌的基因型特征

Journal of Bacteriology & Parasitology Pub Date : 2017-11-13 DOI: 10.4172/2155-9597.1000328

Y. Tyurin, L. Bayazitova, T. A. Chazova, I. Reshetnikova, Tyurina Ny

引用次数: 0

RNA Interference and Nonspecific Controls in Parasitic Helminths 寄生蠕虫的RNA干扰和非特异性对照

Journal of Bacteriology & Parasitology Pub Date : 2017-11-03 DOI: 10.4172/2155-9597.1000325

M. M. Mourão, Sandra Grossi Gava

{"title":"RNA Interference and Nonspecific Controls in Parasitic Helminths","authors":"M. M. Mourão, Sandra Grossi Gava","doi":"10.4172/2155-9597.1000325","DOIUrl":"https://doi.org/10.4172/2155-9597.1000325","url":null,"abstract":"Despite of the remarkable success of RNA interference (RNAi) application in the free-living nematode Caenorhabditis elegans, the exploitation of this powerful technique to helminths parasites with complex life-cycle has been a challenge for parasitologists. It has proved to be effective only for certain parasite species and specific target genes. To date, RNAi is the only methodology available for reverse genetics in trematodes and combined to rescue studies (such heterologous complementation) have been the only alternative to genetic manipulation in nematodes and helminths parasites, thus this subject is of great interest to the scientific community involved in the field. \u0000The RNAi technique is widely used to assess gene function in helminths parasites, in order to elucidate their role in parasite development, mechanisms of drug resistance, and validate therapeutic targets for disease control. \u0000After fifteen years of the first report of RNAi in parasitic helminths, many advances have been achieved, but pitfalls remain as challenges in gene expression manipulation in these organisms. In addition to the methodological particularities of the RNAi technique for each group of helminths, there are still other reasons behind the slow progress of RNAi in those parasites, such; the lack of homology between genes related to parasitism and genes of model organisms and the complex life cycle of these organisms, which results in difficulties for in vitro cultivation. \u0000At this point, a wide assortment of approaches for doubled stranded RNA “delivery” has been proposed. Thus, deeper studies on fundamental aspects of the RNAi methodology in parasitic helminths, such as off-target and the use of controls, can be useful in determining the reason of variations between and within species, facilitating the experimental design and the use of RNAi in the study and eradication of helminths parasites.","PeriodicalId":15045,"journal":{"name":"Journal of Bacteriology & Parasitology","volume":"10 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2017-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78598529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Screening for Latent Tuberculosis Infection among Students of Healthcare Professions and Postgraduates of the Faculty of Medicine of the University of Palermo 巴勒莫大学医学院保健专业学生和研究生潜伏性结核感染筛查

Journal of Bacteriology & Parasitology Pub Date : 2017-10-26 DOI: 10.4172/2155-9597.1000324

M. G. Verso, D. Picciotto, N. LoCascio, E. NotoLaddeca, E. Amodio

{"title":"Screening for Latent Tuberculosis Infection among Students of Healthcare Professions and Postgraduates of the Faculty of Medicine of the University of Palermo","authors":"M. G. Verso, D. Picciotto, N. LoCascio, E. NotoLaddeca, E. Amodio","doi":"10.4172/2155-9597.1000324","DOIUrl":"https://doi.org/10.4172/2155-9597.1000324","url":null,"abstract":"Introduction and objective: Italy is a country with a low incidence of tuberculosis and in the last fifty years the annual number of TB cases decreased from 12,247 to 4,418, showing a reduction of approximately 64% in the number of cases and 71% in incidence. Despite of this encouraging trend, in the last years the epidemiology of tuberculosis changed and today it is a re-emerging infectious. The aim of this study is to measure the prevalence of positivity to tuberculosis infection (latent TB) in students, without any obvious manifestation of disease, attending degree courses of the health care professions and postgraduate medical courses of the School of Medicine of the University of Palermo, Italy. \u0000Materials and methods: A cross-sectional observational study in students of nursing, midwifery, dentistry degree courses and in resident physicians of postgraduate medical schools was carried out from January 2012 to July 2016. Mantoux test was performed and all positive cases were tested with Interferon-Gamma Release Assay (IGRA). \u0000Results: The 1,351 subjects evaluated, 25 (1.8%) resulted positive to Mantoux test; in 17 students (1.2%) the diagnosis was confirmed with IGRA. Positive cases were significantly more frequent among students attending Postgraduated Medical School Courses (p<0.001) and were older than negative cases (p<0.001). \u0000Conclusion: This study suggests that in our geographic area, latent TB shows a relatively low prevalence among students of medical schools. Despite of this evidence, and considering that several students have been found to be positive for TB, this infectious disease has to be considered a re-emerging biohazard that requires preventive strategies for the containment of the risk in exposed workers as well as in the general population.","PeriodicalId":15045,"journal":{"name":"Journal of Bacteriology & Parasitology","volume":"9 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2017-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82425315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effectiveness of quick sequential organ failure assessment (qSOFA) as sepsis screening tool in the emergency department (ED) 快速顺序器官衰竭评估(qSOFA)作为急诊科脓毒症筛查工具的有效性

Journal of Bacteriology & Parasitology Pub Date : 2017-10-23 DOI: 10.4172/2155-9597-c1-044

Ajibola K Ibironke

引用次数: 0

Tips for a successful technology transfer in life sciences 生命科学技术成功转让的秘诀

Journal of Bacteriology & Parasitology Pub Date : 2017-10-17 DOI: 10.4172/2155-9597-C1-040

A. Richard

引用次数: 1

Structure of AcrH-AopB chaperone-translocator complex reveals a role for membrane hairpins in type III secretion system translocon assembly AcrH-AopB伴侣-转运子复合物的结构揭示了膜发夹在III型分泌系统转运体组装中的作用

Journal of Bacteriology & Parasitology Pub Date : 2017-10-17 DOI: 10.4172/2155-9597-C1-036

Mok Yu-Keung

引用次数: 23

Nanoparticle-based vaccine platforms against apicomplexan 基于纳米颗粒的抗顶复蛋白疫苗平台

Journal of Bacteriology & Parasitology Pub Date : 2017-10-03 DOI: 10.4172/2155-9597-C1-034

F. Debierre-Grockiego

引用次数: 1

Linezolid use in Medicine Therapy against Multiresistant Bacteria-AReview 利奈唑胺在多重耐药细菌药物治疗中的应用综述

Journal of Bacteriology & Parasitology Pub Date : 2017-09-22 DOI: 10.4172/2155-9597.1000320

N. S. Mendes, M. Costa, T. Paulino, F. Agostinho, M. Ribeiro, R. Paludo, W. Rodrigues, C. B. Miguel

{"title":"Linezolid use in Medicine Therapy against Multiresistant Bacteria-AReview","authors":"N. S. Mendes, M. Costa, T. Paulino, F. Agostinho, M. Ribeiro, R. Paludo, W. Rodrigues, C. B. Miguel","doi":"10.4172/2155-9597.1000320","DOIUrl":"https://doi.org/10.4172/2155-9597.1000320","url":null,"abstract":"After the description of an element with ability to combat the infectious processes originating from bacteria, starts a race for survival between the interrelationship of species, bacterial and human. With the evolution scientifictechnical, the man was able to synthesize new antibacterial substances, on the other hand the mechanisms of gene evolution enabled the emergence of multidrug-resistant bacteria. Some of this organisms are frequent on hospital environment and have high adaptability to new drugs, such as Staphylococcus aureus and Enterococcus spp. resistant to oxacillin and vancomycin, considered drugs of choice against multidrug-resistant microorganisms. So, a new antibiotics class was developed, superior to vancomycin and oxazolidinone, the linezolid. Thus, the present study aimed at understanding the use of linezolid in drug therapy against multi-resistant bacteria. To perform this study, a literature review of last 10 years was performed. In 2002, after the liberation of the use of linezolid as treatment for infectious processes against gram-positive bacteria, this drug was commonly used throughout the world. Similarly, the pressure of natural selection stood out, and there were records of resistant strains to linezolid. As prospects for control of infections caused by these resistant strains, was approved by the FDA in 2014 the use of drugs with linezolid resistant anti-strains activity. However, we conclude that, in addition to natural selection and genetic variation process, human behavior regarding the use of antibiotics, increases the selection of resistant microorganisms to antibiotic, including linezolid.","PeriodicalId":15045,"journal":{"name":"Journal of Bacteriology & Parasitology","volume":"110 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2017-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76061825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antibiotic Resistance Bacteria from Rivers Water in Algeria 阿尔及利亚河水中的抗生素耐药性细菌

Journal of Bacteriology & Parasitology Pub Date : 2017-09-11 DOI: 10.4172/2155-9597.1000319

K. Djenadi

引用次数: 7