Journal of Analytical Science and Technology最新文献

{"title":"Correction: Antibiotic susceptibility of Staphylococcus aureus with different degrees of biofilm formation","authors":"H. Shin, Sungtae Yang, Yong Lim","doi":"10.1186/s40543-023-00403-3","DOIUrl":"https://doi.org/10.1186/s40543-023-00403-3","url":null,"abstract":"","PeriodicalId":14967,"journal":{"name":"Journal of Analytical Science and Technology","volume":"14 1","pages":"1"},"PeriodicalIF":2.4,"publicationDate":"2023-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49436435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effective investigation of murine femoral bone development utilizing correlative light and electron microscopy (CLEM)","authors":"Yong-Eun Kwon, Jung-Kyun Kim, Youn‑Joong Kim, A. R. Je, H. Guim, Jin-Gyu Kim, krJin‑Gyu Kim","doi":"10.1186/s40543-023-00402-4","DOIUrl":"https://doi.org/10.1186/s40543-023-00402-4","url":null,"abstract":"","PeriodicalId":14967,"journal":{"name":"Journal of Analytical Science and Technology","volume":"14 1","pages":"1-15"},"PeriodicalIF":2.4,"publicationDate":"2023-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45642355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Laboratory evaluation of a prototype portable gas chromatograph (GC) with a flame ionization detector (FID) for toluene, ethylbenzene, and xylenes (TEX) analysis","authors":"Seung-Taek Yang, Jeffrey Wickliffe, G. Kibelka, E. Overton, C. Lungu, Jonghwa Oh","doi":"10.1186/s40543-023-00404-2","DOIUrl":"https://doi.org/10.1186/s40543-023-00404-2","url":null,"abstract":"","PeriodicalId":14967,"journal":{"name":"Journal of Analytical Science and Technology","volume":" ","pages":"1-8"},"PeriodicalIF":2.4,"publicationDate":"2023-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42602483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ag^+ colorimetric sensor based on graphene oxide/nano-platinum composite","authors":"Yanping Qu, I. Yakub, R. Baini, Wenshuo Hu, Lizhen Wang","doi":"10.1186/s40543-023-00401-5","DOIUrl":"https://doi.org/10.1186/s40543-023-00401-5","url":null,"abstract":"","PeriodicalId":14967,"journal":{"name":"Journal of Analytical Science and Technology","volume":"14 1","pages":"1-14"},"PeriodicalIF":2.4,"publicationDate":"2023-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43710803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Liquid chromatography-tandem mass spectrometry for pharmacokinetics evaluation of AZD5305, a selective PARP1 inhibitor, in mice","authors":"Gi Ju Lee, Jin Woo Kim, Hae-In Choi, Jin Young Choi, Kwan Hyung Cho, Tae-Sung Koo","doi":"10.1186/s40543-023-00400-6","DOIUrl":"https://doi.org/10.1186/s40543-023-00400-6","url":null,"abstract":"Abstract Poly (ADP-ribose) polymerase (PARP) inhibitors that are effective against ovarian and breast cancers with breast cancer susceptibility gene (BRCA) mutations have undesirable side effects, such as hematological toxicity. AZD5305, a selective PARP1 inhibitor currently in Phase 1/2 clinical trials, may avoid the side effects caused by PARP2. However, the in vivo pharmacokinetic characteristics of AZD5305 and its bioanalytical methods are unknown. Therefore, a method based on liquid chromatography with tandem mass spectroscopy (LC–MS/MS) was developed and validated to quantify AZD5305 in plasma of mice. Optimal chromatographic separation in terms of peak intensity and symmetry was acquired using a 4-µm Polar-RP 80 Å (2.0 × 150 mm) column with ammonium acetate (5 mM) in distilled water–acetonitrile (50:50, v/v). The retention times of AZD5305 and internal standard (IS; olaparib) were 1.82 min and 1.99 min, respectively. Detection was carried out via triple quadrupole mass spectrometry in positive ion mode employing multiple reaction monitoring transitions at m / z 407.0 → 376.0 for AZD5305 and m / z 435.0 → 281.2 for the IS. The LC–MS/MS method was linear in the range 1–1000 ng/mL with a correlation coefficient ≥ 0.990 and showed acceptable values of major parameters including accuracy, precision, and recovery. Additionally, AZD5305 showed high stability under various conditions. The in vivo and in vitro pharmacokinetics of AZD5305 were successfully characterized by employing the validated LC–MS/MS method. A high level of drug exposure and linear pharmacokinetics were observed after intravenous (IV) bolus and oral administration (PO) of AZD5305 at 0.1–1 mg/kg and 0.1–3 mg/kg, respectively. The bioavailability was close to 100%, and the metabolic stability of AZD5305 in hepatic microsomes of mice and humans was very high. These results may contribute to the improvement of PARP inhibitors that are used to treat malignancies originating from BRCA mutations.","PeriodicalId":14967,"journal":{"name":"Journal of Analytical Science and Technology","volume":"75 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135652827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of central PxxP motif in amphipathic alpha-helical peptides on antimicrobial activity and mode of action","authors":"Hyunhee Lee, Sungtae Yang, Sung-Heui Shin","doi":"10.1186/s40543-023-00398-x","DOIUrl":"https://doi.org/10.1186/s40543-023-00398-x","url":null,"abstract":"","PeriodicalId":14967,"journal":{"name":"Journal of Analytical Science and Technology","volume":" ","pages":"1-10"},"PeriodicalIF":2.4,"publicationDate":"2023-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45853396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Backbone assignment and inhibitor binding studies of IL-33 mutants by NMR spectroscopy","authors":"Minhee Kang, Soyun Kim, Chan Haeng Heo, Sang-Hyun Son, Youngjoo Byun, Young-Ho Jeon","doi":"10.1186/s40543-023-00392-3","DOIUrl":"https://doi.org/10.1186/s40543-023-00392-3","url":null,"abstract":"","PeriodicalId":14967,"journal":{"name":"Journal of Analytical Science and Technology","volume":"14 1","pages":"1-4"},"PeriodicalIF":2.4,"publicationDate":"2023-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42417374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Real-time observation of phase transition from layered to spinel phase under electron beam irradiation","authors":"J. H. Seo, Joon Yong Park, Yong-Il Kim, K. Nam, Jae Hyuck Jang, Ji-Hwan Kwon","doi":"10.1186/s40543-023-00395-0","DOIUrl":"https://doi.org/10.1186/s40543-023-00395-0","url":null,"abstract":"","PeriodicalId":14967,"journal":{"name":"Journal of Analytical Science and Technology","volume":" ","pages":"1-8"},"PeriodicalIF":2.4,"publicationDate":"2023-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47216235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impedance and voltammetry detection of bromate in food samples using NiPcMWCNTs modified glassy carbon electrode","authors":"Sheriff A Balogun, O. E. Fayemi","doi":"10.1186/s40543-023-00396-z","DOIUrl":"https://doi.org/10.1186/s40543-023-00396-z","url":null,"abstract":"","PeriodicalId":14967,"journal":{"name":"Journal of Analytical Science and Technology","volume":"14 1","pages":"1-18"},"PeriodicalIF":2.4,"publicationDate":"2023-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43410383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mass spectrometry-based metabolomics study for delay tomato fruit ripening by sound waves","authors":"M. Jeong, Byoung Joon Ko, J. Y. Kim","doi":"10.1186/s40543-023-00384-3","DOIUrl":"https://doi.org/10.1186/s40543-023-00384-3","url":null,"abstract":"","PeriodicalId":14967,"journal":{"name":"Journal of Analytical Science and Technology","volume":"14 1","pages":"1-11"},"PeriodicalIF":2.4,"publicationDate":"2023-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42510422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}