Journal of Animal Physiology and Animal Nutrition最新文献

{"title":"The Effects of Shrimp Waste Added to Broiler Diets on Growth Performance, Slaughter and Carcass Characteristics, Intestinal Morphology, Bone Traits, and Fatty Acids in the Meat","authors":"Esin Ebru Onbaşılar,&nbsp;Umut Can Gündoğar,&nbsp;Hilal Çapar Akyüz,&nbsp;Sakine Yalçın,&nbsp;Ozan Ahlat,&nbsp;Banu Yüceer Özkul,&nbsp;Berkay Çelebi,&nbsp;Atakan Bundur,&nbsp;Emre Sunay Gebeş,&nbsp;Necmettin Ünal,&nbsp;Ceyhan Özbeyaz","doi":"10.1111/jpn.14064","DOIUrl":"10.1111/jpn.14064","url":null,"abstract":"<p>Recycling animal waste is crucial for the circular economy, promoting environmental and sustainability. This study aimed to assess the impact of shrimp waste added to broiler diets on growth performance, slaughter and carcass characteristics, intestinal morphology, bone traits, and fatty acids in the meat. In the study, 315 ROSS-308 male broiler chicks were utilised as the animal subjects. The experiment consisted of five groups based on the timing and amount of shrimp (<i>Penaeus vannamei</i>) waste addition to their diet (Control [C], 1% added the first 11 days [1% FED], 1% added during fattening [1% DF], 2% added during the first 11 days [2% FED], 2% added during fattening [2% DF]). The differences in body weight, body weight gain, total feed intake and total feed conversion ratio, carcass parameters, relative internal organ weights, and fatty acids of thigh and breast meat among the groups were found to be statistically insignificant (<i>p</i> &gt; 0.05). The addition of shrimp waste to the diet only significantly affected the VH/CD ratio in the jejunum, with the C group showing a lower ratio (<i>p</i> &lt; 0.05). Adding shrimp waste to the diet only affected the seedor index of the femur among the characteristics of the leg bones, and an interaction between the period and the group was observed for this trait (<i>p</i> &lt; 0.05). According to the results, up to 2% shrimp waste can be added to the diet without adversely affecting broiler performance, carcass quality, villus and bone properties, and fatty acid composition. The use of shrimp waste in feed can benefit the broiler industry and protect to environment.</p>","PeriodicalId":14942,"journal":{"name":"Journal of Animal Physiology and Animal Nutrition","volume":"109 2","pages":"477-486"},"PeriodicalIF":2.2,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jpn.14064","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142590627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Growth Performance and Microbial Activity Positively Responded to Interactive Effect of Nitrogen and Phosphorus in Young Holstein Dairy Calves","authors":"Vahid Mahmoudi,&nbsp;Mehdi Kazemi-Bonchenari,&nbsp;Mehdi Hossein Yazdi,&nbsp;Mehdi Mirzaei","doi":"10.1111/jpn.14061","DOIUrl":"10.1111/jpn.14061","url":null,"abstract":"<div>\u0000 \u0000 <p>We hypothesized that nitrogen (N) and phosphorus (P), as two pivotal nutrients that contributed to the growth of growing animals, may have interactive effect on growth performance and microbial development in young calves. For this purpose, feeding two starter protein contents (20% [20CP] vs. 24% [24CP], DM basis) and two phosphorus supplementation levels (0.35% [0.35P] and 0.70% [0.7P], DM basis) was evaluated on growth performance, health indicators, digestibility of nutrients and microbial protein synthesis (MPS), the latter estimated from urinary purine derivatives (PDs). Forty-eight female Holstein calves (3 days of age) were assigned randomly to the following treatments: 20CP-0.35P, 20CP-0.7P, 24CP-0.35P and 24CP-0.7P (<i>n</i> = 12, each). Milk feeding schedule was identical among treatments until weaning (d 59), but study lasted until d 73. Feeding 24CP compared to 20CP diet tended to improve starter intake, increased average daily gain (ADG) during pre-weaning period (<i>p</i> &lt; 0.05), and final body weight (<i>p</i> = 0.01). Higher P supplementation has marginal effect on starter intake but improved ADG (pre-weaning; <i>p</i> = 0.02) and microbial activity by greater MPS (<i>p</i> = 0.02) compared to 0.35P. The greatest starter intake, the most favourable general appearance score, the highest withers height, the highest hip height, the greatest organic matter and neutral detergent digestibility, and the greatest MPS were found when calves fed diets contained 24CP along with 0.7P in starter. Based on the current study results, N and P have separate effects on the growth performance of young calves; however, their positive interaction can be attributable to growth performance and microbial development, especially during the pre-weaning period.</p>\u0000 </div>","PeriodicalId":14942,"journal":{"name":"Journal of Animal Physiology and Animal Nutrition","volume":"109 2","pages":"467-476"},"PeriodicalIF":2.2,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142576221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Estimation of Metabolizable Amino Acids and Energy Requirements and Development of Mathematical Models to Predict Average Daily Gain for Beef Cattle","authors":"Jiaqi Wang,&nbsp;Chun Shen,&nbsp;Guangyong Zhao,&nbsp;Meng M. Li","doi":"10.1111/jpn.14065","DOIUrl":"10.1111/jpn.14065","url":null,"abstract":"<div>\u0000 \u0000 <p>This study aimed to estimate metabolizable energy (ME), protein (MP) and amino acids (MAA) requirements for maintenance and growth, and to develop a mathematical model to predict ADG for beef cattle using a meta-regression approach. A data set including 91 sources of literature with 385 treatments was assembled after data collection and screening. To estimate nutrient requirements for maintenance and growth, metabolizable nutrient intakes were regressed on metabolic body weight (MBW) and ADG using a mixed model with a random study effect. A multiple linear regression model was derived to predict ADG using MBW and nutrient intakes as independent variables. The random forest analysis was used to identify the importance of independent variables associated with ADG and compare it with the multiple linear regression model. The accuracy of the model was evaluated by Monte−Carlo cross-evaluation. The ME and MP requirements for maintenance were 0.56 MJ/BW^0.75 and 4.31 g/BW^0.75. The maintenance requirements of metabolizable arginine (Arg), histidine (His), isoleucine (Ile), leucine (Leu), lysine (Lys), methionine (Met), threonine (Thr), tryptophan (Trp), phenylalanine (Phe), valine (Val) and total AA were 0.044, 0.073, 0.013, 0.13, 0.10, 0.024, 0.075, 0.026, 0.088, 0.11 and 0.76 g/BW^0.75. The estimated ME and MP requirements for growth were 45.8 MJ/kg ADG and 398.7 g/kg ADG. The growth requirements of metabolizable Arg, His, Ile, Leu, Lys, Met, Thr, Trp, Phe, Val and total AA were 4.5, 6.4, 7.3, 24.0, 2.9, 2.4, 6.1, 1.7, 9.5, 9.3 and 74.5 g/kg ADG. The multiple linear regression analysis showed that ADG was positively correlated with intakes of ME, ether extract, starch and Trp (<i>p</i> &lt; 0.05). The results of the Monte−Carlo cross-evaluation showed that the multiple regression model was more accurate in predicting ADG than the random forest model. ME and MP requirements for maintenance are consistent with previous studies, but requirements for growth tend to be overestimated. Future studies are needed to evaluate MAA requirements. An accurate model was developed to predict ADG, offering a theoretical basis and guidance to improve growth performance and feed conversion efficiency for beef cattle.</p>\u0000 </div>","PeriodicalId":14942,"journal":{"name":"Journal of Animal Physiology and Animal Nutrition","volume":"109 2","pages":"456-466"},"PeriodicalIF":2.2,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142545546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Growth Performance, Haematological Parameters and Serum Biochemistry of the Flathead Grey Mullet Mugil cephalus Under Recirculating Aquaculture System and Traditional Culture Systems","authors":"Mohamed F. Badran,&nbsp;Mervat A. M. Ali,&nbsp;Mohamed S. Yusuf","doi":"10.1111/jpn.14062","DOIUrl":"10.1111/jpn.14062","url":null,"abstract":"<div>\u0000 \u0000 <p>The present investigation explored the growth performance, haematological parameters and serum biochemistry of flathead grey mullet under recirculating aquaculture system (RAS) and traditional culture systems. Nine hundred healthy fish, weighing 43.80 ± 3.55 g and length 16.54 ± 0.82 cm were randomly distributed to three treatments of RAS and traditional culture systems (T₁: 20% of water changed daily; T₂: once-through system 250 L/h; T₃: RAS—20% of water changed weekly) in nine concrete tanks of 4000 L at stocking density of 100 fish/tank and each treatment had three replicates. Fish were fed (33.1% crude protein, 3 mm pellets) twice a day at a rate of 3% for 12 weeks. These findings suggest that the T₃ followed by T₂ led to notable improvements in growth performance compared to other culture systems. Significantly elevated values of weight gain, length gain, specific growth rate, average daily gain and survival % were observed in T₃. The RBCs exhibited a significant decrease under T₂. Haemoglobin concentrations and WBC counts significantly increased under RAS. Significant values of mean cell haemoglobin and mean cell haemoglobin concentration were recorded in T₂. Total protein, albumin and globulin enhanced significantly under RAS, whereas the highest values of cortisol were observed in T₂ and T₃. These findings demonstrate that the RAS followed by once-through system significantly improve growth performance, feed efficiency and survival, as well as enhancing the haematology and serum biochemical status of flathead grey mullet. In conclusion, RAS provides ideal conditions for optimizing physiological functions, growth performance and fish health.</p>\u0000 </div>","PeriodicalId":14942,"journal":{"name":"Journal of Animal Physiology and Animal Nutrition","volume":"109 2","pages":"449-455"},"PeriodicalIF":2.2,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142545575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Protein/Carbohydrate Ratio in the Diet Affects Zootechnical Performance and the Regulation of Intermediary Metabolism in Juveniles Tambaqui (Colossoma macropomum)","authors":"Gabriela Castellani Carli,&nbsp;Mariana Palma,&nbsp;Thaise Mota Satiro,&nbsp;Hugo Henrique D'Amore Soares,&nbsp;Jeisson Emerson Casimiro Ferrari,&nbsp;Ivan Viegas,&nbsp;Leonardo Susumu Takahashi","doi":"10.1111/jpn.14060","DOIUrl":"10.1111/jpn.14060","url":null,"abstract":"<div>\u0000 \u0000 <p>The use of carbohydrates in animal feed is a way to save protein in the diet. This study evaluated the effect of protein/starch ratio on the performance, hepatic metabolism, and body composition of juvenile tambaqui (<i>Colossoma macropomum</i>). Six isoenergetic experimental diets were formulated containing three levels of digestible protein (P: 230, 260 and 290 g kg⁻¹) and two levels of starch (S: 180 and 280 g kg⁻¹): P23S18, P23S28, P26S18, P26S28, P29S18 and P29S28. Juveniles tambaqui (<i>N</i> = 288; initial weight = 30.0 ± 3.8 g) were fed experimental diets for 90 days and the zootechnical performance was evaluated. Nine fish from each treatment group were sampled to determine somatic indices, blood metabolites, tissue energy reserves, body composition and activity of key hepatic enzymes. Blood triglycerides, hepatosomatic index, liver and muscle lipids, and hepatic glycogen increased significantly with starch while blood glucose, triglycerides and cholesterol, muscle lipids were significantly impacted by protein levels. Fish-fed S28 had increased feed intake (1714–1829 g; <i>p</i> &lt; 0.0001) and fish-fed diet P26S18 had a higher protein efficiency rate (23.62%; <i>p</i> = 0.0356). Fish fed P23 had lower crude protein retention in the carcass (<i>p</i> = 0.0018) and high lipogenesis and lipid deposition in the muscle (<i>p</i> = 0.0069). These results suggest that dietary carbohydrates have a protein-sparing effect. Tambaqui adapted well to diets containing starch, even at higher levels, resulting in an overall increase in lipogenesis from S18 to S28. Thus, we recommend P26S18 as a cost-effective feed that ensures both zootechnical performance and quality of the final product.</p>\u0000 </div>","PeriodicalId":14942,"journal":{"name":"Journal of Animal Physiology and Animal Nutrition","volume":"109 2","pages":"423-436"},"PeriodicalIF":2.2,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142500843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antioxidant Capacity of Thyme (Thymus vulgaris) Essential Oil and Its Effect on In Vivo Fertility of Rams Subjected to Testicle Heat Stress","authors":"Samia Khnissi,&nbsp;Imène Ben Salem,&nbsp;Bochra Bejaoui,&nbsp;Sami Fattouch,&nbsp;Souha ben Mustapha,&nbsp;Rami Haj-Kacem,&nbsp;Naceur M'Hamdi,&nbsp;Patrick Martin,&nbsp;Maria Dattena,&nbsp;Narjess Lassoued","doi":"10.1111/jpn.14063","DOIUrl":"10.1111/jpn.14063","url":null,"abstract":"<p>The detrimental effects of hyperthermia on the testes and the protective effect of thyme essential oil against testicular damage induced by this stress in rams were studied. Twenty-four rams of the Barbarine breed with an average weight of 62.5 ± 0.3 kg and an average age of 24 ± 0.6 months. The experiment consisted of inducing localized heat stress on the first group of rams by applying heat bags to both testicles of six rams (G s). The second group underwent the same heat stress on the testes but received orally 100 µL/day/animal of thyme essential oil (G s-he). A positive control did not undergo stress but received thyme essential oil (G he) with the same doses as the (G s-he) group, and the negative control did not undergo either stress or receive the essential oil of thyme (G c). One hundred twenty-eight adult ewes of the same breed divided into four groups of 32 ewes were used to study the effect of different treatments on the in vivo ram's fertility. Ewes are synchronized and we have applied natural mating with oestrus control, the reproduction balance sheet is calculated after lambing. The results showed that tests of heat stress (HS) negatively affect semen quality but did not cause infertility. However, neither tests for heat stress nor treatment with thyme EO significantly affected the haematological profile. The study of the effect of heat stress on the testes on fertility in vivo showed a drop in the number of females who were fertilized at the first oestrus and consequently a drop in fertility. However, the rams that suffered the same stress but were treated with EO thymus recorded an improvement in these parameters.</p>","PeriodicalId":14942,"journal":{"name":"Journal of Animal Physiology and Animal Nutrition","volume":"109 2","pages":"437-448"},"PeriodicalIF":2.2,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jpn.14063","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142521975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Standardized Ileal Digestibility of Amino Acids in Hybrid Rye Ground to Two Particle Sizes and Fed With or Without Multienzyme Supplement to Young Growing Pigs","authors":"Jichen Song,&nbsp;Claus H. Heuer,&nbsp;Rob Patterson,&nbsp;Charles M. Nyachoti","doi":"10.1111/jpn.14053","DOIUrl":"10.1111/jpn.14053","url":null,"abstract":"<p>A newly developed hybrid rye with enhanced ergot resistance has potential as an alternative energy source for pigs. An experiment was conducted to evaluate the effects of particle size (PS) and multienzyme supplement (MES) on the apparent total tract digestibility (ATTD) of energy and nutrients and the standardized ileal digestibility (SID) of amino acids (AA) in hybrid rye fed to growing pigs. Bono and Gatano, two hybrid rye varieties, were ground to either a coarse (1111 and 1210 μm) or a fine (594 and 717 μm) PS using a hammer mill. Eighteen ileal-cannulated barrows (initial BW = 18.2 ± 1.0 kg) were randomly assigned to 1 of 9 dietary treatments in a replicated 9 × 3 incomplete Latin square design to give six observations per treatment. Among the nine experimental diets, eight featured two hybrid rye varieties (Bono or Gatano), either coarsely or finely ground, as the only source of AA with or without MES, while an N-free diet was used to estimate the endogenous losses of AA at the distal ileum. All diets contained titanium dioxide as an indigestible marker. Each period lasted 9 days, with the first 5 days being for adaptation followed by 2 days each for faecal and ileal digesta collection. Data were analysed using the MIXED procedure of SAS, with the final model having variety, PS, MES, their two-way interactions, and a three-way interaction. No interactions were noted except that the apparent ileal digestibility and SID of crude protein (CP) and most AA in Gatano had greater effects of MES than Bono (Variety × MES; <i>p</i> &lt; 0.05). The ATTD of dry matter (DM), gross energy (GE) and CP were greater (<i>p</i> &lt; 0.05) in Bono diets than in Gatano diets. Finely ground hybrid rye diets had higher (<i>p</i> &lt; 0.05) ATTD of neutral detergent fibre assayed with a heat stable amylase and expressed inclusive of residual ash (NDF) and ether extract compared to coarsely ground hybrid rye diets. Dietary MES supplementation increased (<i>p</i> &lt; 0.05) the ATTD of DM, GE, CP, NDF, acid detergent fibre expressed inclusive of residual ash, and ash in hybrid rye diets. In conclusion, the nutrients digestibility of hybrid rye can be affected by its variety. PS reduction improved the nutrient digestibility in hybrid rye, and MES supplementation improved the energy and AA digestibility in hybrid rye fed to growing pigs.</p>","PeriodicalId":14942,"journal":{"name":"Journal of Animal Physiology and Animal Nutrition","volume":"109 2","pages":"411-422"},"PeriodicalIF":2.2,"publicationDate":"2024-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jpn.14053","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142500842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes in Microbial Ecosystems and Serum Metabolomics by Diet Supplementation With Enramycin in Weaning Piglets","authors":"Kana Umemura,&nbsp;Shiho Miyata,&nbsp;Guanlin Lyu,&nbsp;Yoshihito Suda,&nbsp;Yuto Yoshimoto,&nbsp;Taiki Terajima,&nbsp;Hong Liu,&nbsp;Jun Kambe,&nbsp;Yuko Makioka-Itaya,&nbsp;Ryo Inoue,&nbsp;Chunmei Li,&nbsp;Yuki Yamamoto,&nbsp;Kentaro Nagaoka","doi":"10.1111/jpn.14059","DOIUrl":"10.1111/jpn.14059","url":null,"abstract":"<div>\u0000 \u0000 <p>Antibiotics are used in swine production for growth promotion and disease prevention, raising concerns about environmental contamination and antibiotic resistance. In this study, we investigated the effects of enramycin supplementation on piglet growth, gut microbiota and blood metabolites. Enramycin promotes piglet growth and temporarily reduces diarrhoea. Gut microbiota analysis revealed changes in microbial composition, including an increase in the abundance of <i>Limosilactobacillus reuteri</i>. Metabolomic analysis has identified elevated levels of dimethylglycine, a known growth-promoting factor, in the enramycin group. Liver gene expression analysis revealed increased mRNA levels of ALDH and dimethylglycine dehydrogenase, which are enzymes involved in dimethylglycine metabolism. The enramycin-treated group had a higher concentration of acetic acid in caecal contents, and their caecal acetic acid concentrations were positively correlated with the abundance of <i>L. reuteri</i> and the content of serum dimethylglycine, respectively. These findings suggest that the promotion effect of enramycin on piglet growth is related to the gut microbiota, blood metabolites and liver gene expression, which provide insights into antibiotic alternatives for swine production.</p>\u0000 </div>","PeriodicalId":14942,"journal":{"name":"Journal of Animal Physiology and Animal Nutrition","volume":"109 2","pages":"402-410"},"PeriodicalIF":2.2,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142466083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Natural Feed Supplements From Crustacean Processing Side Streams for Improved Growth of Finfishes and Crustaceans: A Review","authors":"Ancy Ashraf,&nbsp;Sarasan Sabu,&nbsp;Abhilash Sasidharan,&nbsp;Kappat Valiyapeediyekkal Sunooj","doi":"10.1111/jpn.14058","DOIUrl":"10.1111/jpn.14058","url":null,"abstract":"<p>Natural feed additives of plant/animal/microbial origin are researched as supplements in aquaculture to improve the properties of feed, minimize the usage of chemical alternatives, reduce food safety risks and ensure sustainability to combat global food and nutritional security. Side streams generated during shellfish processing possess valuable ingredients: protein, lipids, carotenoids, minerals and chitins. Considering the current trend of organic farming and antibiotic-free fish and shellfish, crustacean processing side streams and their derivatives seem promising and emerging resources as natural additives/supplements for formulating high-quality feeds with superior benefits. Lower concentrations of chitin and chitosan in diets are reported to stimulate the growth of shellfish and finfish under controlled conditions. Oligomers of chitosan and nano-chitosan are also the other potential derivatives as natural supplements in feed for better growth performance of aquaculture varieties. This review focuses on the significance of crustacean processing side streams and their derivatives, especially shrimp head meal, chitin, chitosan and chitosan oligosaccharides as potential natural additives in aquafeeds for promoting the growth performance of cultured fin fishes and shell fishes. Utilization in aquafeeds and the development of natural value-added supplements from crustacean processing side streams, especially shrimp head and shell leftover, offer an answer to the negative environmental impact due to its dumping; reduce the dependency on food fish for fish meal production &amp; fishmeal for aquafeeds; solution to maintain the economic viability of the fish farmers &amp; industry as well as to ensure the supply of safer and healthy aquatic foods to meet the objectives of sustainable development goals.</p>","PeriodicalId":14942,"journal":{"name":"Journal of Animal Physiology and Animal Nutrition","volume":"109 2","pages":"376-401"},"PeriodicalIF":2.2,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jpn.14058","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142466084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Soybean Agglutinin Induced Apoptotic Effects by Down-Regulating ANXA2 Through FAK Pathway in IPEC-J2 Cells","authors":"Tianjiao E,&nbsp;Chengyu Xu,&nbsp;Xiapu Fan,&nbsp;Jiawei Liu,&nbsp;Jinpeng Zhao,&nbsp;Nan Bao,&nbsp;Yuan Zhao,&nbsp;Mohammed Hamdy Farouk,&nbsp;Yun Ji,&nbsp;Zhenlong Wu,&nbsp;Li Pan,&nbsp;Guixin Qin","doi":"10.1111/jpn.14051","DOIUrl":"10.1111/jpn.14051","url":null,"abstract":"<div>\u0000 \u0000 <p>Soybean agglutinin (SBA) is an anti-nutritional factor in soybean, possesses toxic effects by binding to intestinal epithelial cells, and finally interferes the digestion and absorption of nutrients in humans and animals. Annexin A2 (ANXA2) is one of the SBA-specific binding proteins in intestinal epithelial cells and participates in multiple cellular biological processes. However, whether SBA affects apoptosis through ANXA2 and its apoptosis-related pathway remains unclear. IPEC-J2 is an ideal model to study human intestinal health. Therefore, this study aims to investigate the effects of ANXA2 on SBA-induced intestinal epithelial cell apoptosis and the related pathway mechanism using IPEC-J2 as a cell model. The results showed that SBA induced the apoptosis through FAK signal pathway and decreased the gene and protein expressions of ANXA2 in IPEC-J2. The expression of ANXA2 protein had a negative correlation with the apoptosis rates, and a positive correlation with the expression of FAK protein and FAK pathway downstream proteins. In conclusion, SBA induced apoptosis of IPEC-J2 cells by downregulating the expression of ANXA2, which activated the FAK pathway. These findings highlight the toxic mechanism of SBA, which will provide basis for studying the toxicity mechanisms of other food-derived anti-nutrients and provide a new perspective for human gastrointestinal health and related cancer treatment.</p>\u0000 </div>","PeriodicalId":14942,"journal":{"name":"Journal of Animal Physiology and Animal Nutrition","volume":"109 2","pages":"350-361"},"PeriodicalIF":2.2,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142466085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}